Counteracting arsenic toxicity: Curcumin to the rescue?

Protective effects of curcumin on biochemical and molecular changes in sodium arsenite‐induced oxidative damage in embryonic fibroblast cells

(2019) Mehmet Can Perker et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Transient receptor potential melastatin 4 contributes to early-stage endothelial injury induced by arsenic trioxide

(2019) Chun-Xiao Yu et al.   TOXICOLOGY LETTERS

Combinatorial drug delivery strategy employing nano -curcumin and nano -MiADMSA for the treatment of arsenic intoxication in mouse

(2018) Pramod Kushwaha et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PI3K/Akt/GSK3β induced CREB activation ameliorates arsenic mediated alterations in NMDA receptors and associated signaling in rat hippocampus: Neuroprotective role of curcumin

(2018) Pranay Srivastava et al.   NEUROTOXICOLOGY

Nerve growth factor prevents arsenic-induced toxicity in PC12 cells through the AKT/GSK-3β/NFAT pathway

(2018) Zhen Tan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Immunological dysfunction in chronic arsenic exposure: From subclinical condition to skin cancer

(2018) Sebastian Yu et al.   JOURNAL OF DERMATOLOGY

Therapeutic potential of curcumin in diabetic complications

(2018) Negin Parsamanesh et al.   PHARMACOLOGICAL RESEARCH

Prevalence of brucellosis in ruminants in Bangladesh

(2018) MS Rahman et al.   VETERINARNI MEDICINA

Effects of curcumin on hypoxia-inducible factor as a new therapeutic target

(2018) Afsane Bahrami et al.   PHARMACOLOGICAL RESEARCH

Effect of curcumin on kidney histopathological changes, lipid peroxidation and total antioxidant capacity of serum in sodium arsenite-treated mice

(2017) Hamid Reza Momeni et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Curcumin Attenuates N-Nitrosodiethylamine-Induced Liver Injury in Mice by Utilizing the Method of Metabonomics

(2017) Peiyu Qiu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Therapeutic effects of curcumin in inflammatory and immune-mediated diseases: A nature-made jack-of-all-trades?

(2017) Elham Abdollahi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ameliorative effect of two Ayurvedic herbs on experimentally induced arsenic toxicity in calves

(2017) Suman Biswas et al.   JOURNAL OF ETHNOPHARMACOLOGY

Curcumin: A potentially powerful tool to reverse cisplatin-induced toxicity

(2017) Ramin Rezaee et al.   PHARMACOLOGICAL RESEARCH

Metabolism, toxicity and anticancer activities of arsenic compounds

(2017) Islam Khairul et al.   Oncotarget

Effects of curcumin on serum cytokine concentrations in subjects with metabolic syndrome: A post-hoc analysis of a randomized controlled trial

(2016) Yunes Panahi et al.   BIOMEDICINE & PHARMACOTHERAPY

Difluorinated Curcumin: A Promising Curcumin Analogue with Improved Anti-Tumor Activity and Pharmacokinetic Profile

(2016) Amir Abbas Momtazi et al.   CURRENT PHARMACEUTICAL DESIGN

Metabolism and toxicity of arsenicals in mammals

(2016) Adeel Sattar et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Inorganic arsenic: A non-genotoxic carcinogen

(2016) Samuel M. Cohen et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Autophagy in acute kidney injury

(2016) Gur P. Kaushal et al.   KIDNEY INTERNATIONAL

Role of microRNAs in the Therapeutic Effects of Curcumin in Non-Cancer Diseases

(2016) Amir Abbas Momtazi et al.   Molecular Diagnosis & Therapy

Protective Effect of Curcumin by Modulating BDNF/DARPP32/CREB in Arsenic-Induced Alterations in Dopaminergic Signaling in Rat Corpus Striatum

(2016) Pranay Srivastava et al.   MOLECULAR NEUROBIOLOGY

Exaggerated arsenic nephrotoxicity in female mice through estrogen-dependent impairments in the autophagic flux

(2016) Akihiko Kimura et al.   TOXICOLOGY

Molecular targets of curcumin for cancer therapy: an updated review

(2016) Pandima Devi Kasi et al.   TUMOR BIOLOGY

Biochemical and Molecular Alterations Following Arsenic-Induced Oxidative Stress and Mitochondrial Dysfunction in Rat Brain

(2015) Chandra Prakash et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Ameliorative efficacy of tetrahydrocurcumin against arsenic induced oxidative damage, dyslipidemia and hepatic mitochondrial toxicity in rats

(2015) M. Muthumani et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Lipopolysaccharide (LPS) exposure differently affects allergic asthma exacerbations and its amelioration by intranasal curcumin in mice

(2015) Asha Kumari et al.   CYTOKINE

Arsenic and fluoride contaminated groundwaters: A review of current technologies for contaminants removal

(2015) Sachin V. Jadhav et al.   JOURNAL OF ENVIRONMENTAL MANAGEMENT

Neuroprotective effects of curcumin on endothelin-1 mediated cell death in hippocampal neurons

(2015) Dorota L. Stankowska et al.   NUTRITIONAL NEUROSCIENCE

Effect of curcuminoids on oxidative stress: A systematic review and meta-analysis of randomized controlled trials

(2015) Amirhossein Sahebkar et al.   Journal of Functional Foods

Metabolomic study in plasma, liver and kidney of mice exposed to inorganic arsenic based on mass spectrometry

(2014) M. A. García-Sevillano et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Arsenic Exposure May Be a Risk Factor for Alzheimer’s Disease

(2014) Shahriar Gharibzadeh et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

Protective action of curcumin and nano-curcumin against arsenic-induced genotoxicity in rats in vivo

(2014) Palanisamy Sankar et al.   MOLECULAR BIOLOGY REPORTS

Unraveling the mechanism of neuroprotection of curcumin in arsenic induced cholinergic dysfunctions in rats

(2014) Pranay Srivastava et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The Broad Scope of Health Effects from Chronic Arsenic Exposure: Update on a Worldwide Public Health Problem

(2013) Marisa F. Naujokas et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Effects of nanoparticle-encapsulated curcumin on arsenic-induced liver toxicity in rats

(2013) Palanisamy Sankar et al.   ENVIRONMENTAL TOXICOLOGY

Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion

(2013) Shuang Gao et al.   FOOD AND CHEMICAL TOXICOLOGY

Immunomodulatory effects of nanocurcumin in arsenic-exposed rats

(2013) Palanisamy Sankar et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The biology of the glucocorticoid receptor: New signaling mechanisms in health and disease

(2013) Robert H. Oakley et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Curcumin Protects Human Keratinocytes against Inorganic Arsenite-Induced Acute Cytotoxicity through an NRF2-Dependent Mechanism

(2013) Rui Zhao et al.   Oxidative Medicine and Cellular Longevity

Are Curcuminoids Effective C-Reactive Protein-Lowering Agents in Clinical Practice? Evidence from a Meta-Analysis

(2013) Amirhossein Sahebkar   PHYTOTHERAPY RESEARCH

In utero and early life arsenic exposure in relation to long-term health and disease

(2013) Shohreh F. Farzan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oral nanoparticulate curcumin combating arsenic-induced oxidative damage in kidney and brain of rats

(2013) Palanisamy Sankar et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Arsenic upregulates the expression of angiotensin II Type I receptor in mouse aortic endothelial cells

(2013) Ekhtear Hossain et al.   TOXICOLOGY LETTERS

Curcumin encapsulated in chitosan nanoparticles: A novel strategy for the treatment of arsenic toxicity

(2012) Abhishek Yadav et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Modulation of arsenic-induced epidermal growth factor receptor pathway signalling by resveratrol

(2012) Katharine J. Herbert et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The Targets of Curcumin

(2012) Hongyu Zhou et al.   CURRENT DRUG TARGETS

The glomerular basement membrane

(2012) Jeffrey H. Miner   EXPERIMENTAL CELL RESEARCH

Novel lipid based oral formulation of curcumin: Development and optimization by design of experiments approach

(2012) Yogesh B. Pawar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Arsenic Promotes Ubiquitinylation and Lysosomal Degradation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channels in Human Airway Epithelial Cells

(2012) Jennifer M. Bomberger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protective effect of curcumin against arsenic-induced apoptosis in murine splenocytesin vitro

(2012) Saleem Khan et al.   Journal of Immunotoxicology

Transient receptor potential melastatin 4 and cell death

(2012) J. Marc Simard et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Sodium arsenite-induced cardiotoxicity in rats: protective role of p-coumaric acid, a common dietary polyphenol

(2012) Nagalakshmi Prasanna et al.   TOXICOLOGY MECHANISMS AND METHODS

Transient receptor potential melastatin 4 inhibition prevents lipopolysaccharide-induced endothelial cell death

(2011) Alvaro Becerra et al.   CARDIOVASCULAR RESEARCH

Arsenic-Associated Oxidative Stress, Inflammation, and Immune Disruption in Human Placenta and Cord Blood

(2011) Sultan Ahmed et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Apoptosis of peripheral blood mononuclear cells in children exposed to arsenic and fluoride

(2011) Diana O. Rocha-Amador et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Angiotensin II and the vascular phenotype in hypertension

(2011) Carmine Savoia et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Concomitant exposure to arsenic and organophosphates on tissue oxidative stress in rats

(2011) Nidhi Dwivedi et al.   FOOD AND CHEMICAL TOXICOLOGY

Arsenic-induced oxidative stress and its reversibility

(2011) Swaran J.S. Flora   FREE RADICAL BIOLOGY AND MEDICINE

Arsenic affects expression and processing of amyloid precursor protein (APP) in primary neuronal cells overexpressing the Swedish mutation of human APP

(2011) Sergio Zarazúa et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Neuroprotective efficacy of curcumin in arsenic induced cholinergic dysfunctions in rats

(2011) Rajesh S. Yadav et al.   NEUROTOXICOLOGY

Arsenic Exposure and Toxicology: A Historical Perspective

(2011) Michael F. Hughes et al.   TOXICOLOGICAL SCIENCES

The Arsenic Exposure Hypothesis for Alzheimer Disease

(2010) Gordon Gong et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Protective Role of Moringa oleifera (Sajina) Seed on Arsenic-Induced Hepatocellular Degeneration in Female Albino Rats

(2010) Sandip Chattopadhyay et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

Arsenic toxicity in mammals and aquatic animals: A comparative biochemical approach

(2010) Juliane Ventura-Lima et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Curcumin prevents DNA damage and enhances the repair potential in a chronically arsenic-exposed human population in West Bengal, India

(2010) Madhumita Roy et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Curcumin supplementation protects from genotoxic effects of arsenic and fluoride

(2010) Hemlata Tiwari et al.   FOOD AND CHEMICAL TOXICOLOGY

Arsenic-induced myocardial injury: Protective role of Corchorus olitorius leaves

(2010) Anup K. Das et al.   FOOD AND CHEMICAL TOXICOLOGY

Concentrations of cadmium, lead, mercury and arsenic in Chinese market milled rice and associated population health risk

(2010) Yongzhong Qian et al.   FOOD CONTROL

Curcumin protects DNA damage in a chronically arsenic-exposed population of West Bengal

(2010) Jaydip Biswas et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Arsenic trioxide induces endoplasmic reticulum stress-related events in neutrophils

(2010) François Binet et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Neuroprotective effect of curcumin in arsenic-induced neurotoxicity in rats

(2010) Rajesh S. Yadav et al.   NEUROTOXICOLOGY

Evaluation of the serum catalase and myeloperoxidase activities in chronic arsenic-exposed individuals and concomitant cytogenetic damage

(2010) Mayukh Banerjee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Monoisoamyl dimercaptosuccinic acid abrogates arsenic-induced developmental toxicity in human embryonic stem cell-derived embryoid bodies: Comparison with in vivo studies

(2009) S.J.S. Flora et al.   BIOCHEMICAL PHARMACOLOGY

Low-Dose Arsenic Compromises the Immune Response to Influenza A Infection in Vivo

(2009) Courtney D. Kozul et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Influence of repeated preexposure to arsenic on acetaminophen-induced oxidative stress in liver of male rats

(2009) Ayyasamy Manimaran et al.   FOOD AND CHEMICAL TOXICOLOGY

Redox-sensitive regulation of gene expression in human primary macrophages exposed to inorganic arsenic

(2009) Emilie Bourdonnay et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Effect of Arsenic on Regulatory T Cells

(2009) B. Hernández-Castro et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Inhibition of Androgen Receptor Transcriptional Activity as a Novel Mechanism of Action of Arsenic

(2009) Adena E. Rosenblatt et al.   MOLECULAR ENDOCRINOLOGY

Global effects of inorganic arsenic on gene expression profile in human macrophages

(2009) Emilie Bourdonnay et al.   MOLECULAR IMMUNOLOGY

Attenuation of arsenic neurotoxicity by curcumin in rats

(2009) Rajesh S. Yadav et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Immunotoxicity and biodistribution analysis of arsenic trioxide in C57Bl/6 mice following a 2-week inhalation exposure

(2009) Scott W. Burchiel et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Arsenic moiety in gallium arsenide is responsible for neuronal apoptosis and behavioral alterations in rats

(2009) Swaran J.S. Flora et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of in utero arsenic exposure on child immunity and morbidity in rural Bangladesh

(2009) Rubhana Raqib et al.   TOXICOLOGY LETTERS

A Systematic Review of Arsenic Exposure and Its Social and Mental Health Effects with Special Reference to Bangladesh

(2009) Johanna Brinkel et al.   International Journal of Environmental Research and Public Health

Synthesis and Anti-bacterial Properties of Mono-carbonyl Analogues of Curcumin

(2008) Guang Liang et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Phase II Trial of Curcumin in Patients with Advanced Pancreatic Cancer

(2008) N. Dhillon et al.   CLINICAL CANCER RESEARCH

Drinking-Water Arsenic Exposure Modulates Gene Expression in Human Lymphocytes from a U.S. Population

(2008) Angeline S. Andrew et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Elevated Human Telomerase Reverse Transcriptase Gene Expression in Blood Cells Associated with Chronic Arsenic Exposure in Inner Mongolia, China

(2008) Jinyao Mo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Sodium arsenite induced biochemical perturbations in rats: Ameliorating effect of curcumin

(2008) Mokhtar I. Yousef et al.   FOOD AND CHEMICAL TOXICOLOGY

Ameliorating effect of curcumin on sodium arsenite-induced oxidative damage and lipid peroxidation in different rat organs

(2008) Fatma M. El-Demerdash et al.   FOOD AND CHEMICAL TOXICOLOGY

Biomarkers of oxidative stress and damage in human populations exposed to arsenic

(2008) Andrea De Vizcaya-Ruiz et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Anti-ischemic Effect of Curcumin in Rat Brain

(2008) Pradeep K. Shukla et al.   NEUROCHEMICAL RESEARCH

Moderate perinatal arsenic exposure alters neuroendocrine markers associated with depression and increases depressive-like behaviors in adult mouse offspring

(2008) Ebany J. Martinez et al.   NEUROTOXICOLOGY

Embryotoxicity hazard assessment of cadmium and arsenic compounds using embryonic stem cells

(2008) T.C. Stummann et al.   TOXICOLOGY

Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity

(2008) Xu-Jun Qin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Arsenic interferes with the signaling transduction pathway of T cell receptor activation by increasing basal and induced phosphorylation of Lck and Fyn in spleen cells

(2008) Gerson A. Soto-Peña et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Curcumin as “Curecumin”: From kitchen to clinic

(2007) Ajay Goel et al.   BIOCHEMICAL PHARMACOLOGY

Arsenic as an Endocrine Disruptor: Arsenic Disrupts Retinoic Acid Receptor–and Thyroid Hormone Receptor–Mediated Gene Regulation and Thyroid Hormone–Mediated Amphibian Tail Metamorphosis

(2007) Jennifer C. Davey et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The role of protein binding of trivalent arsenicals in arsenic carcinogenesis and toxicity

(2007) Kirk T. Kitchin et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Protective effect of Curcumin, the active principle of turmeric (Curcuma longa) in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes in rat brain

(2007) M BISHNOI et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR