Article
Agronomy
Susmita Dey, Ashok Biswas, Siqi Huang, Defang Li, Liangliang Liu, Yong Deng, Aiping Xiao, Ziggiju Mesenbet Birhanie, Jiangjiang Zhang, Jianjun Li, Youcai Gong
Summary: The study revealed that varieties Y49 and M33 showed high chlorophyll and carotenoid content and could withstand low-temperature stress by accumulating different antioxidants. Osmolytes compounds significantly increased in Y49 and M33, serving as a defense mechanism for osmotic readjustment to reduce oxidative damage induced by low temperature. PCA and hierarchical cluster analysis identified three groups, with Y49 and M33 being low-temperature tolerant, M18 and W57 being intermediate, and Y38, T8, and Y1 being low temperature susceptible.
Review
Chemistry, Multidisciplinary
Marwa A. M. Abdel-Razek, Miada F. Abdelwahab, Usama Ramadan Abdelmohsen, Ashraf N. E. Hamed
Summary: Corchorus olitorius L. is a nutritious leafy vegetable with potential nutraceutical benefits. Its leaves are rich in minerals, vitamins, and various bioactive compounds, which have shown multiple health-promoting effects.
Article
Biochemistry & Molecular Biology
Rui Yan, Jie Ding, Yuanjie Wei, Qianlei Yang, Xiaoyun Zhang, Hairu Huang, Zhuoyue Shi, Yue Feng, Heran Li, Hengdong Zhang, Wenjun Ding, Yan An
Summary: Melatonin protects against NaAsO2-induced heart malformations in zebrafish by inhibiting oxidative stress and apoptosis.
Article
Environmental Sciences
Dingnian Bi, Dan Zheng, Mingyang Shi, Qian Hu, Hongling Wang, Haiyan Zhi, Didong Lou, Aihua Zhang, Yong Hu
Summary: According to the study, arsenic, a widely distributed environmental poison, can cause liver injury by inducing oxidative stress and damaging lysosomes and autophagy through the activation of the SESTRIN2/AMPK/ULK1 pathway. This eventually leads to necrosis in the liver. Additionally, the damage to lysosomes and autophagy can be alleviated by NAC treatment but aggravated by Leu-peptin treatment, and the decrease of RIPK1 and RIPK3 expression levels can mitigate the necrotic effects.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Biotechnology & Applied Microbiology
Shaimaa El-Tohory, Wenzhi Zeng, Jiesheng Huang, Mohamed G. Moussa, Liming Dong, Abdelkader Mohamed, Omar Khalifa, Muhammad Hamzah Saleem, Mostafa Zhran, M. A. Salama, Jingwei Wu
Summary: Heavy metals in farmlands pose a serious threat to food security. Intercropping and biochar amendments have been found to be effective strategies for remediation. This study compared the effects of intercropping and biochar amendments on reducing the potential risk of Cd in Corchorus olitorius and Zea mays in alkaline soils, and found that the combination of intercropping and biochar amendment significantly increased metal removal efficiency and improved Cd remediation efficiency in different crops.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2023)
Article
Biochemistry & Molecular Biology
Mirza Hasanuzzaman, Md. Rakib Hossain Raihan, Ebtihal Khojah, Bassem N. Samra, Masayuki Fujita, Kamrun Nahar
Summary: The supplementation of biochar and chitosan significantly alleviated the oxidative damage caused by salt stress in jute plants by enhancing antioxidant systems and glyoxalase enzyme activities, improving stress tolerance, reducing Na+ accumulation and ionic toxicity, and decreasing the Na+/K+ ratio.
Article
Food Science & Technology
Moon Ho Do, Hyun Hee L. Lee, Yoonsook Kim, Hye-Bin Lee, Eunjung Lee, Jae Ho Park, Ho-Young Park
Summary: This study suggests that water-soluble extract from molokhia (WM) can alleviate alcohol-induced liver damage by improving gut microbial composition and gut barrier function.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Engineering, Environmental
Canhui Deng, Zemao Yang, Chaohua Cheng, Zhigang Dai, Qing Tang, Ying Xu, Xiaojun Chen, Jianguang Su
Summary: The study found that low concentrations of GO can promote the growth of jute, stimulate antioxidant enzyme activities, reduce oxidative stress, facilitate Cd uptake, and improve Cd tolerance; while high concentrations of GO can inhibit plant growth, decrease Cd uptake, and increase oxidative stress.
ENVIRONMENTAL ENGINEERING SCIENCE
(2021)
Article
Polymer Science
Songmin Oh, Do-Yeong Kim
Summary: This study extracted and characterized the mucilage from Corchorus olitorius L. and investigated its potential applications in various fields. The mucilage showed good solubility, swelling index, water-holding capacity, and oil-binding capacity, as well as antioxidant activity. It can be utilized as a new hydrocolloid source with potential applications in foods, cosmetics, and pharmaceuticals.
Article
Chemistry, Multidisciplinary
Yanchun Deng, Xiai Yang, Jiquan Chen, Sa Yang, Haiyang Chi, Chenxiao Chen, Xiushi Yang, Chunsheng Hou
Summary: The study found that natural plant nanocrystalline cellulose (NCC) has antiviral effects in honey bees. Feeding bees infected with Israeli acute paralysis virus (IAPV) with jute NCC (JNCC) can reduce virus proliferation and improve gut health. Furthermore, JNCC can regulate gut microbiota, promote the expression of antimicrobial peptides (AMPs), and activate antiviral signaling pathways.
Article
Crystallography
Nada S. Al-Kadhi, Ghadah M. Al-Senani, Rasmiah S. Almufarij, Omar H. Abd-Elkader, Nasrallah M. Deraz
Summary: This study aimed to develop a self-combustion method for preparing copper and cobalt ferrites using dry leaves of the Corchorus olitorius plant. The fabrication of CuFe2O4 and CoFe2O4 with spinel-type structures and the Fd3m space group was confirmed through XRD and FTIR investigations. The materials showed two stages of thermal behavior, with the first stage indicating the formation of reacting oxides and the second stage indicating ferrite growth. Surface morphological analysis displayed the formation of uniform and nanosized particles, with the samples containing CoFe2O4 showing superior surface properties compared to those without CuFe2O4. Magnetic characteristics evaluated using VSM showed that cobalt ferrites had higher magnetization, squareness, and coercivity compared to copper ferrites.
Article
Biology
Oladele Ayobami Afolabi, Babatunde Adebola Alabi, Richard Adedamola Ajike, Olubunmi Simeon Oyekunle, Wakeel Adegoke, Abodunrin Adebayo Ojetola
Summary: This study investigated the effectiveness of phytochemicals combined with surgical detorsion in the management of testicular torsion (TT). The results showed that surgical detorsion alone was not effective and additional medication was needed. The use of phytochemicals reduced oxidative stress and inflammation, and suppressed pro-apoptotic protein expression, leading to improved outcomes in testicular torsion.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2023)
Article
Agricultural Engineering
Shah Md Tamim Kabir, Md. Sabbir Hossain, Kazi Khayrul Bashar, Ummay Honi, Borhan Ahmed, Emdadul Mannan Emdad, Md. Monjurul Alam, Md. Samiul Haque, Md. Shahidul Islam
Summary: The ethylene-responsive element (AP2/ERF) is a key and conserved transcription factor in plants, playing a vital role in regulating plant growth, development, and stress response. The CoAP2/ERF genes in dark jute are regulated by various growth stages and stresses, with some genes significantly upregulated under waterlogging stress conditions. Gene evolution analysis showed dark jute separated from cacao and cotton millions of years ago, and gene duplication played a role in expanding and enhancing the functions of superfamily genes.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Plant Sciences
Zemao Yang, Shilin Tian, Xiangkong Li, Zhigang Dai, An Yan, Zhong Chen, Jiquan Chen, Qing Tang, Chaohua Cheng, Ying Xu, Canhui Deng, Chan Liu, Ling Kang, Dongwei Xie, Jian Zhao, Xiaojun Chen, Xiaoyu Zhang, Yupeng Wu, Alei Li, Jianguang Su
Summary: We investigated the domestication and improvement of dark jute through multi-omics analysis, and found that soil salinity played an important role in domestication. We also identified abundant candidate loci and speculated a protein that may affect fiber yield.
Article
Multidisciplinary Sciences
Omar H. Abd-Elkader, Nasrallah M. Deraz, Lotfi Aleya
Summary: The main objective of this study was to develop a method for preparing Ni and Mn ferrites, which are important materials in high-frequency applications. These ferrites were made by assisting combustion with dried leaves of Corchorus olitorius and then heating them to 700 ?. Several characterization methods were used to determine the properties of the as-prepared materials. The results showed that the method used is cheap, economical, environmentally friendly, and easy to produce the studied ferrites.
Article
Chemistry, Multidisciplinary
Tarun Kumar Dua, Simran Giri, Gouranga Nandi, Ranabir Sahu, Tapan Kumar Shaw, Paramita Paul
Summary: The green synthesis of silver nanoparticles (AgNPs) using an aqueous Eupatorium adenophorum leaf extract as a bioreductant is reported in this article. The E. adenophorum extract not only served as a bioreductant but also acted as a capping agent to stabilize the nanoparticles. Various characterization techniques were adopted to analyze the biosynthesized AgNPs. The AgNPs showed improved antioxidant, antibacterial and photocatalytic activities, suggesting their potential applications in various fields.
Article
Chemistry, Organic
Sovan Dey, Arindam Das, Ram Naresh Yadav, Palash Jyoti Boruah, Prerana Bakli, Tania Baishya, Koushik Sarkar, Anup Barman, Ranabir Sahu, Biplab Maji, Amit Kumar Paul, Md. Firoj Hossain
Summary: A mild and eco-friendly visible-light-induced synthesis of 2-(2-hydrazinyl) thiazole from readily accessible starting materials is reported. The reaction proceeds without the need for a metal catalyst or extrinsic photosensitizer, and only requires visible light and a green solvent. The synthesized compounds showed significant antioxidant and antidiabetic properties in vitro.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Tania Baishya, Priya Das, Gouhar Jahan Ashraf, Tarun Kumar Dua, Paramita Paul, Gouranga Nandi, Malay Bhattacharya, Ranabir Sahu
Summary: Different parts of Camellia sinensis (L.) were extracted using solvents of varying polarity to examine their phytochemical profiling and biological activities. The highest levels of total phenolic and flavonoid contents were observed in polar solvents, which also showed increased antioxidant, anti-inflammatory, and antidiabetic activities. HPTLC analysis revealed that polar solvents like hydroalcohol, methanol, and water yielded the highest levels of phenolic acids, epigallocatechin gallate, gallocatechin, and theaflavin, particularly in tea leaves. The findings suggested that polar solvents and young tea leaves were beneficial for obtaining extracts and that phenolics exhibited potent antioxidant, anti-inflammatory, and antidiabetic properties.
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
(2023)
Article
Pharmacology & Pharmacy
Ankita Mallick, Ranabir Sahu, Gouranga Nandi, Tarun Kumar Dua, Tapan Kumar Shaw, Ankita Dhar, Aditya Kanu, Paramita Paul
Summary: The purpose of this study was to prepare a suitable carrier system to enhance the bioavailability of valacyclovir (VCV) and reduce dose-related side effects for the treatment of herpes. Liposomes encapsulating VCV were synthesized using thin film hydration and reverse-phase evaporation methods. The liposomes showed nanosize range, good colloidal stability, and appreciable drug loading capability. In vitro release studies revealed a biphasic release pattern with initial burst release followed by continuous drug release. The findings suggest that VCV formulated as a liposome can effectively treat herpes with a lower dose and improved bioavailability.
JOURNAL OF PHARMACEUTICAL INNOVATION
(2023)
Review
Chemistry, Medicinal
Bhuvi Sachdeva, Punya Sachdeva, Arvind Negi, Shampa Ghosh, Sungsoo Han, Saikat Dewanjee, Saurabh Kumar Jha, Rakesh Bhaskar, Jitendra Kumar Sinha, Ana Claudia Paiva-Santos, Niraj Kumar Jha, Kavindra Kumar Kesari
Summary: Chitin is a biopolymer derived from marine crustaceans and organisms like bacteria, fungi, and algae, which offers biodegradability and biocompatibility properties suitable for biomedical applications. Its deacetylated derivative, chitosan, also possesses similar properties and can be used as a support material in biomedical applications. Additionally, both chitin and chitosan have intrinsic material properties such as antioxidant, antibacterial, and antitumor activities. This paper focuses on the use of chitin and chitosan biopolymers in drug delivery strategies for cancer treatment.
Review
Biochemistry & Molecular Biology
Nilanjan Ghosh, Leena Chacko, Hiranmoy Bhattacharya, Jayalakshmi Vallamkondu, Sagnik Nag, Abhijit Dey, Tanushree Karmakar, P. Hemachandra Reddy, Ramesh Kandimalla, Saikat Dewanjee
Summary: Diabetes mellitus (DM) and cardiovascular complications often occur together, creating a challenging situation. The development of diabetic cardiomyopathy (DCM) involves complex pathophysiological pathways at the metabolic and molecular level, leading to structural and functional alterations of the heart. Glucagon-like peptide-1 (GLP-1) analogues and sodium-glucose cotransporter-2 (SGLT-2) inhibitors have shown promising results in improving cardiovascular outcomes in diabetes. This article highlights the pathways contributing to DCM and discusses potential future therapies.
Review
Biochemistry & Molecular Biology
Hafiza Padinharayil, Jinsu Varghese, Mithun Chacko John, Golgodu Krishnamurthy Rajanikant, Cornelia M. Wilson, Minnatallah Al-Yozbaki, Kaviyarasi Renu, Saikat Dewanjee, Rupa Sanyal, Abhijit Dey, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Alex George
Summary: Continuous revision of the histologic and stage-wise classification of lung cancer by the World Health Organization (WHO) supports therapeutic advances and accurate diagnosis. Cancer epidemiologic data provide helpful information for cancer prevention and management. Global cancer mortality projections indicate that cancer will become the leading cause of death, particularly non-small cell lung cancer (NSCLC) which accounts for a significant portion of lung cancers. Early diagnosis and proper management play crucial roles in NSCLC therapies. Advanced techniques, such as immune checkpoint inhibitors (ICIs) and targeted molecular therapies, have improved the treatment of late-stage NSCLC. However, the improvement of cancer biomarkers and the development of prospective studies are needed for better therapeutic outcomes.
Article
Biochemistry & Molecular Biology
Md. Latifur Rahman, Subhajit Mandal, Priya Das, Gouhar Jahan Ashraf, Tarun Kumar Dua, Paramita Paul, Gouranga Nandi, Ranabir Sahu
Summary: This study aimed to investigate the effects of different extraction methods on the antioxidant activity and phenolic profiling of black rice. The highest contents of various phenolic compounds and antioxidant activity were observed in microwave-assisted extraction (MAE). MAE also showed the most abundant phenolic compounds. The results suggest that extraction techniques have an impact on the bioactive compounds and their properties.
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
(2023)
Review
Endocrinology & Metabolism
Paramita Paul, Leena Chacko, Tarun K. Dua, Pratik Chakraborty, Udita Paul, Vishwakarma Vishal Phulchand, Niraj K. Jha, Saurabh K. Jha, Ramesh Kandimalla, Saikat Dewanjee
Summary: Diabetic nephropathy is a serious complication of diabetes mellitus, and early detection and effective treatment are crucial. Nanosystems have shown promise in the diagnosis and treatment of diabetic nephropathy, offering advantages such as early and accurate diagnosis, site-specific delivery, and improved pharmacokinetic profile.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Pharmacology & Pharmacy
Simran Giri, G. Dey, R. Sahu, Paramita Paul, G. Nandi, T. K. Dua
Summary: Woodfordia fruticosa is a traditional medicinal plant with numerous therapeutic properties. Phytochemical investigations have identified 61 compounds belonging to various classes, such as glycosides, terpenes, flavonoids, tannins, sterols, phenolics, and essential oils. Pharmacological studies have shown that the plant possesses antihyperglycemic, antioxidant, anti-inflammatory, analgesic, hepatoprotective, antibacterial, gastroprotective, and wound healing properties. However, further studies on the isolated compounds are needed to fully explore the plant's potential applications.
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2023)
Article
Food Science & Technology
Subhajit Mandal, Md. Latifur Rahman, Priya Das, Gouhar Jahan Ashraf, Tarun Kumar Dua, Paramita Paul, Gouranga Nandi, Ranabir Sahu
Summary: This study investigated the effects of maceration, ultrasonic, and microwave-assisted extraction on the phenolic compounds of Tulaipanji rice flour. It was found that microwave-assisted extraction showed the highest phenolic content and antioxidant activity, particularly in bound phenolics.
INTERNATIONAL JOURNAL OF FOOD ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Abhijit Changder, Sanat Kumar Mandal, Saurav Sarkar, Riyasree Paul, Ananya Ghosh, Paramita Paul, Tarun Kumar Dua, Ranabir Sahu, Gouranga Nandi, Lakshmi Kanta Ghosh
Summary: The present study evaluated the application of Cassia fistula seed galactomannan (CFSG) as a tablet binder for diclofenac sodium. The research confirmed the excellent binding capacity of CFSG and its potential as an alternative tablet binder.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
