High-content imaging-based pooled CRISPR screens in mammalian cells

Pooled CRISPR screens with imaging on microraft arrays reveals stress granule-regulatory factors

(2020) Emily C. Wheeler et al.   NATURE METHODS

High‐throughput, microscope‐based sorting to dissect cellular heterogeneity

(2020) Nicholas Hasle et al.   Molecular Systems Biology

Imaging-based pooled CRISPR screening reveals regulators of lncRNA localization

(2019) Chong Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unravelling nuclear size control

(2019) Helena Cantwell et al.   CURRENT GENETICS

TICRR Contributes to Tumorigenesis Through Accelerating DNA Replication in Cancers

(2019) Qin Yu et al.   Frontiers in Oncology

Optical Pooled Screens in Human Cells

(2019) David Feldman et al.   CELL

High-throughput genetic screens using CRISPR–Cas9 system

(2018) Jiyeon Kweon et al.   ARCHIVES OF PHARMACAL RESEARCH

Large‐scale image‐based profiling of single‐cell phenotypes in arrayed CRISPR‐Cas9 gene perturbation screens

(2018) Reinoud de Groot et al.   Molecular Systems Biology

A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters

(2018) Kiryl D. Piatkevich et al.   Nature Chemical Biology

Label-free prediction of three-dimensional fluorescence images from transmitted-light microscopy

(2018) Chawin Ounkomol et al.   NATURE METHODS

RNAi/CRISPR Screens: from a Pool to a Valid Hit

(2018) Anne Schuster et al.   TRENDS IN BIOTECHNOLOGY

Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens

(2018) Aleksandra Wroblewska et al.   CELL

Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks

(2018) Adam J. Rubin et al.   CELL

RAD-ical New Insights into RAD51 Regulation

(2018) Meghan R. Sullivan et al.   Genes

DNA2—An Important Player in DNA Damage Response or Just Another DNA Maintenance Protein?

(2017) Elzbieta Pawłowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pooled CRISPR screening with single-cell transcriptome readout

(2017) Paul Datlinger et al.   NATURE METHODS

Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

(2016) Diego Adhemar Jaitin et al.   CELL

Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

(2016) Atray Dixit et al.   CELL

Mechanisms behind Topoisomerase II SUMOylation in chromosome segregation

(2016) Makoto M. Yoshida et al.   CELL CYCLE

Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion

(2016) Maria Sokolova et al.   CELL CYCLE

Applications of CRISPR technologies in research and beyond

(2016) Rodolphe Barrangou et al.   NATURE BIOTECHNOLOGY

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

(2016) Max A Horlbeck et al.   eLife

The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochores

(2016) Sushama Sivakumar et al.   eLife

Recent advances in understanding nuclear size and shape

(2016) Richik N. Mukherjee et al.   Nucleus

Recent advances in understanding nuclear size and shape

(2016) Richik N. Mukherjee et al.   Nucleus

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

(2015) Oren Parnas et al.   CELL

Photostick: a method for selective isolation of target cells from culture

(2015) Miao-Ping Chien et al.   Chemical Science

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

(2014) Luke A. Gilbert et al.   CELL

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

The spindle and kinetochore–associated (Ska) complex enhances binding of the anaphase-promoting complex/cyclosome (APC/C) to chromosomes and promotes mitotic exit

(2014) Sushama Sivakumar et al.   MOLECULAR BIOLOGY OF THE CELL

Rad51 Regulates Cell Cycle Progression by Preserving G2/M Transition in Mouse Embryonic Stem Cells

(2014) Sang-Wook Yoon et al.   STEM CELLS AND DEVELOPMENT

Nucleoporin Nup62 maintains centrosome homeostasis

(2013) Chieko Hashizume et al.   CELL CYCLE

Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells

(2013) M. Kampmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

(2013) Tim Wang et al.   SCIENCE

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

(2012) Mar Carmena et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nuclear size regulation: from single cells to development and disease

(2012) Lisa J. Edens et al.   TRENDS IN CELL BIOLOGY

Cell-Nonautonomous Regulation of C. elegans Germ Cell Death by kri-1

(2010) Shu Ito et al.   CURRENT BIOLOGY

A vertebrate gene, ticrr, is an essential checkpoint and replication regulator

(2010) C. L. Sansam et al.   GENES & DEVELOPMENT

Topoisomerase IIα maintains genomic stability through decatenation G2 checkpoint signaling

(2010) J J Bower et al.   ONCOGENE

Sizing up the nucleus: nuclear shape, size and nuclear-envelope assembly

(2009) M. Webster et al.   JOURNAL OF CELL SCIENCE

Human Dna2 Is a Nuclear and Mitochondrial DNA Maintenance Protein

(2009) J. P. Duxin et al.   MOLECULAR AND CELLULAR BIOLOGY

A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex

(2008) R. Gassmann et al.   GENES & DEVELOPMENT

The NIMA-family kinase Nek6 phosphorylates the kinesin Eg5 at a novel site necessary for mitotic spindle formation

(2008) J. Rapley et al.   JOURNAL OF CELL SCIENCE