Extracellular RNAs in Bacterial Infections: From Emerging Key Players on Host-Pathogen Interactions to Exploitable Biomarkers and Therapeutic Targets

Small RNAs in eucaryotes: new clues for amplifying microRNA benefits

(2020) Bernardetta Ledda et al.   Cell and Bioscience

Comparative Genomics and Evolutionary Analysis of RNA-Binding Proteins of Burkholderia cenocepacia J2315 and Other Members of the B. cepacia Complex

(2020) Joana R. Feliciano et al.   Genes

Extracellular Vesicles for Cancer Therapy: Impact of Host Immune Response

(2020) Katie E. Gilligan et al.   Cells

Fecal microRNAs as Innovative Biomarkers of Intestinal Diseases and Effective Players in Host-Microbiome Interactions

(2020) Meysam Sarshar et al.   Cancers

Staphylococcus aureus secretes immunomodulatory RNA and DNA via membrane vesicles

(2020) Blanca V. Rodriguez et al.   Scientific Reports

Helicobacter pylori-Derived Outer Membrane Vesicles (OMVs): Role in Bacterial Pathogenesis?

(2020) Miroslaw Jarzab et al.   Microorganisms

Identification of Genes Involved in Biogenesis of Outer Membrane Vesicles (OMVs) in Salmonella enterica Serovar Typhi

(2019) Jan Nevermann et al.   Frontiers in Microbiology

The current state and future directions of RNAi-based therapeutics

(2019) Ryan L. Setten et al.   NATURE REVIEWS DRUG DISCOVERY

Extracellular vesicles deliver Mycobacterium RNA to promote host immunity and bacterial killing

(2019) Yong Cheng et al.   EMBO REPORTS

Diversity and heterogeneity of extracellular RNA in human plasma

(2019) Adeline Galvanin et al.   BIOCHIMIE

The sncRNA Zoo: a repository for circulating small noncoding RNAs in animals

(2019) Tobias Fehlmann et al.   NUCLEIC ACIDS RESEARCH

Interplay Between ncRNAs and Cellular Communication: A Proposal for Understanding Cell-Specific Signaling Pathways

(2019) Santiago Ramón y Cajal et al.   Frontiers in Genetics

Extracellular RNAs in periodontopathogenic outer membrane vesicles promote TNF-α production in human macrophages and cross the blood–brain barrier in mice

(2019) Eun-Chong Han et al.   FASEB JOURNAL

sncRNAs packaged by Helicobacter pylori outer membrane vesicles attenuate IL-8 secretion in human cells

(2019) Hongxia Zhang et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Microbe Profile: Pseudomonas aeruginosa: opportunistic pathogen and lab rat

(2019) Stephen P. Diggle et al.   MICROBIOLOGY-SGM

The secRNome of Listeria monocytogenes Harbors Small Noncoding RNAs That Are Potent Inducers of Beta Interferon

(2019) Renate Frantz et al.   mBio

An RNA-Binding Protein Secreted by a Bacterial Pathogen Modulates RIG-I Signaling

(2019) Alessandro Pagliuso et al.   Cell Host & Microbe

miR‐18a promotes Mycobacterial survival in macrophages via inhibiting autophagy by down‐regulation of ATM

(2019) Qiulu Yuan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Bacterial regulatory RNAs: complexity, function, and putative drug targeting

(2018) Hong-Leong Cheah et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Clinical utility of circulating non-coding RNAs — an update

(2018) Simone Anfossi et al.   Nature Reviews Clinical Oncology

Outer Membrane Vesicles: Current Status and Future Direction of These Novel Vaccine Adjuvants

(2018) Kuang Tan et al.   Frontiers in Microbiology

Exosomes in Pathogen Infections: A Bridge to Deliver Molecules and Link Functions

(2018) Wenchao Zhang et al.   Frontiers in Immunology

Helicobacter pylori Outer Membrane Vesicle Size Determines Their Mechanisms of Host Cell Entry and Protein Content

(2018) Lorinda Turner et al.   Frontiers in Immunology

The RNA Complement of Outer Membrane Vesicles From Salmonella enterica Serovar Typhimurium Under Distinct Culture Conditions

(2018) Antoine Malabirade et al.   Frontiers in Microbiology

Small Noncoding Regulatory RNAs from Pseudomonas aeruginosa and Burkholderia cepacia Complex

(2018) Tiago Pita et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Types and origins of bacterial membrane vesicles

(2018) Masanori Toyofuku et al.   NATURE REVIEWS MICROBIOLOGY

Secretable Small RNAs via Outer Membrane Vesicles in Periodontal Pathogens

(2017) J.-W. Choi et al.   JOURNAL OF DENTAL RESEARCH

Prophage-triggered membrane vesicle formation through peptidoglycan damage in Bacillus subtilis

(2017) Masanori Toyofuku et al.   Nature Communications

Salmonella produce microRNA-like RNA fragment Sal-1 in the infected cells to facilitate intracellular survival

(2017) Hongwei Gu et al.   Scientific Reports

A Novel Role of Listeria monocytogenes Membrane Vesicles in Inhibition of Autophagy and Cell Death

(2017) Svitlana Vdovikova et al.   Frontiers in Cellular and Infection Microbiology

Outer Membrane Vesicles (OMVs) of Gram-negative Bacteria: A Perspective Update

(2017) Arif Tasleem Jan   Frontiers in Microbiology

Circulating microRNAs as Potential Biomarkers of Infectious Disease

(2017) Carolina N. Correia et al.   Frontiers in Immunology

Membrane association of the bacterial riboregulator Hfq and functional perspectives

(2017) Antoine Malabirade et al.   Scientific Reports

Sources and Functions of Extracellular Small RNAs in Human Circulation

(2016) Joëlle V. Fritz et al.   Annual Review of Nutrition

Isolation and Characterization of a microRNA-size Secretable Small RNA in Streptococcus sanguinis

(2016) Ji-Woong Choi et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Hfq: a multifaceted RNA chaperone involved in virulence

(2016) Joana R Feliciano et al.   Future Microbiology

Commercial Dairy Cow Milk microRNAs Resist Digestion under Simulated Gastrointestinal Tract Conditions

(2016) Abderrahim Benmoussa et al.   JOURNAL OF NUTRITION

Grad-seq guides the discovery of ProQ as a major small RNA-binding protein

(2016) Alexandre Smirnov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Two-Component Regulatory System Impacts Extracellular Membrane-Derived Vesicle Production in Group A Streptococcus

(2016) Ulrike Resch et al.   mBio

Explosive cell lysis as a mechanism for the biogenesis of bacterial membrane vesicles and biofilms

(2016) Lynne Turnbull et al.   Nature Communications

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

(2016) Sandro Roier et al.   Nature Communications

KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

(2016) Andrew J. McKenzie et al.   Cell Reports

The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting

(2016) Laura Santangelo et al.   Cell Reports

A Novel Mechanism of Host-Pathogen Interaction through sRNA in Bacterial Outer Membrane Vesicles

(2016) Katja Koeppen et al.   PLoS Pathogens

Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction

(2016) Matthew J Shurtleff et al.   eLife

Roles, Functions, and Mechanisms of Long Non-coding RNAs in Cancer

(2016) Yiwen Fang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Uropathogenic Escherichia coli Releases Extracellular Vesicles That Are Associated with RNA

(2016) Cherie Blenkiron et al.   PLoS One

Evidence of the presence of nucleic acids and β-glucan in the matrix of non-typeable Haemophilus influenzae in vitro biofilms

(2016) Mirian Domenech et al.   Scientific Reports

Exosomes: Vehicles of Intercellular Signaling, Biomarkers, and Vectors of Cell Therapy

(2015) Stella Kourembanas   Annual Review of Physiology

MicroRNA expression profiles of bovine milk exosomes in response to Staphylococcus aureus infection

(2015) Jiajie Sun et al.   BMC GENOMICS

Talk among yourselves: RNA sponges mediate cross talk between functionally related messenger RNAs

(2015) M. S. Azam et al.   EMBO JOURNAL

Vps4A functions as a tumor suppressor by regulating the secretion and uptake of exosomal microRNAs in human hepatoma cells

(2015) Jin-xing Wei et al.   HEPATOLOGY

Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi

(2015) Lisa Brown et al.   NATURE REVIEWS MICROBIOLOGY

New hypotheses derived from the structure of a flaviviral Xrn1-resistant RNA: Conservation, folding, and host adaptation

(2015) Jeffrey S Kieft et al.   RNA Biology

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

(2015) Margaret Alexander et al.   Nature Communications

The extracellular RNA complement ofEscherichia coli

(2015) Anubrata Ghosal et al.   MicrobiologyOpen

Functional Advantages of Porphyromonas gingivalis Vesicles

(2015) Meng-Hsuan Ho et al.   PLoS One

MiR-486 and miR-92a Identified in Circulating HDL Discriminate between Stable and Vulnerable Coronary Artery Disease Patients

(2015) Loredan S. Niculescu et al.   PLoS One

Membrane vesicle-mediated release of bacterial RNA

(2015) Annika E. Sjöström et al.   Scientific Reports

Effects of different target sites on antisense RNA-mediated regulation of gene expression

(2014) Hongmarn Park et al.   BMB Reports

Small RNAs from plants, bacteria and fungi within the order Hypocreales are ubiquitous in human plasma

(2014) Meabh Beatty et al.   BMC GENOMICS

Identification and Characterization of Outer Membrane Vesicle-Associated Proteins in Salmonella enterica Serovar Typhimurium

(2014) Jaewoo Bai et al.   INFECTION AND IMMUNITY

Microvesicles: ubiquitous contributors to infection and immunity

(2014) Frances W. Lai et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Proteomic Characterization of the Outer Membrane Vesicle of Pseudomonas putida KT2440

(2014) Chi-Won Choi et al.   JOURNAL OF PROTEOME RESEARCH

Biogenesis and multifaceted roles of outer membrane vesicles from Gram-negative bacteria

(2014) H. M. Kulkarni et al.   MICROBIOLOGY-SGM

Physiological roles of small RNA molecules

(2014) C. Michaux et al.   MICROBIOLOGY-SGM

Search for MicroRNAs Expressed by Intracellular Bacterial Pathogens in Infected Mammalian Cells

(2014) Yuki Furuse et al.   PLoS One

Bacterial Vesicles in Marine Ecosystems

(2014) S. J. Biller et al.   SCIENCE

Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells

(2014) Mario Leonardo Squadrito et al.   Cell Reports

The carrying pigeons of the cell: exosomes and their role in infectious diseases caused by human pathogens

(2014) Adam Fleming et al.   Pathogens and Disease

Antibiotic drugs targeting bacterial RNAs

(2014) Weiling Hong et al.   Acta Pharmaceutica Sinica B

Classification and Comparison of Small RNAs from Plants

(2013) Michael J. Axtell   Annual Review of Plant Biology

Identification of microRNA-Size, Small RNAs in Escherichia coli

(2013) Sung-Min Kang et al.   CURRENT MICROBIOLOGY

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

RIG-I detects infection with liveListeriaby sensing secreted bacterial nucleic acids

(2012) Zeinab Abdullah et al.   EMBO JOURNAL

Unbiased approach to profile the variety of small non-coding RNA of human blood plasma with massively parallel sequencing technology

(2012) Dmitry V. Semenov et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy

(2012) Y. Lee et al.   HUMAN MOLECULAR GENETICS

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

(2012) Eduard Hergenreider et al.   NATURE CELL BIOLOGY

Stable Extracellular RNA Fragments of Mycobacterium tuberculosis Induce Early Apoptosis in Human Monocytes via a Caspase-8 Dependent Mechanism

(2012) Andrés Obregón-Henao et al.   PLoS One

The Complex Exogenous RNA Spectra in Human Plasma: An Interface with Human Gut Biota?

(2012) Kai Wang et al.   PLoS One

The mammalian microRNA response to bacterial infections

(2012) Ana Eulalio et al.   RNA Biology

The hallmarks of cancer

(2012) Tony Gutschner et al.   RNA Biology

Extracellular miRNAs: the mystery of their origin and function

(2012) Andrey Turchinovich et al.   TRENDS IN BIOCHEMICAL SCIENCES

A Bilayer-Couple Model of Bacterial Outer Membrane Vesicle Biogenesis

(2012) J. W. Schertzer et al.   mBio

Crp Induces Switching of the CsrB and CsrC RNAs in Yersinia pseudotuberculosis and Links Nutritional Status to Virulence

(2012) Ann Kathrin Heroven et al.   Frontiers in Cellular and Infection Microbiology

Regulation of Listeria virulence: PrfA master and commander

(2011) Aitor de las Heras et al.   CURRENT OPINION IN MICROBIOLOGY

Analysis of microRNA-size, small RNAs in Streptococcus mutans by deep sequencing

(2011) Heon-Jin Lee et al.   FEMS MICROBIOLOGY LETTERS

Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice

(2011) Lilla Turiák et al.   Journal of Proteomics

The small RNA PhrS stimulates synthesis of the Pseudomonas aeruginosa quinolone signal

(2011) Elisabeth Sonnleitner et al.   MOLECULAR MICROBIOLOGY

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biological Functions and Biogenesis of Secreted Bacterial Outer Membrane Vesicles

(2010) Adam Kulp et al.   Annual Review of Microbiology

Variation of Physiochemical Properties and Cell Association Activity of Membrane Vesicles with Growth Phase in Pseudomonas aeruginosa

(2010) Y. Tashiro et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Microparticles

(2010) Sebastian F. Mause et al.   CIRCULATION RESEARCH

Outer Membrane Vesicles of Helicobacter pylori TK1402 are Involved in Biofilm Formation

(2009) Hideo Yonezawa et al.   BMC MICROBIOLOGY

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Caught at its own game: regulatory small RNA inactivated by an inducible transcript mimicking its target

(2009) N. Figueroa-Bossi et al.   GENES & DEVELOPMENT

Gram-positive bacteria produce membrane vesicles: Proteomics-based characterization of Staphylococcus aureus-derived membrane vesicles

(2009) Eun-Young Lee et al.   PROTEOMICS

The birth and death of microRNA genes in Drosophila

(2008) Jian Lu et al.   NATURE GENETICS

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS