Small RNAs in eucaryotes: new clues for amplifying microRNA benefits

The Potential for microRNA Therapeutics and Clinical Research

(2019) Johora Hanna et al.   Frontiers in Genetics

Small RNA profiling of low biomass samples: identification and removal of contaminants

(2018) Anna Heintz-Buschart et al.   BMC BIOLOGY

The potential atheroprotective role of plant MIR156a as a repressor of monocyte recruitment on inflamed human endothelial cells

(2018) Dongxia Hou et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Identification of exosome-like nanoparticle-derived microRNAs from 11 edible fruits and vegetables

(2018) Juan Xiao et al.   PeerJ

Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota

(2018) Yun Teng et al.   Cell Host & Microbe

Detection of Plant miRNAs Abundance in Human Breast Milk

(2017) Anna Lukasik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Survey of 800+ data sets from human tissue and body fluid reveals xenomiRs are likely artifacts

(2017) Wenjing Kang et al.   RNA

Plant-derived phosphocholine facilitates cellular uptake of anti-pulmonary fibrotic HJT-sRNA-m7

(2017) Jianchao Du et al.   Science China-Life Sciences

Plant microRNAs in larval food regulate honeybee caste development

(2017) Kegan Zhu et al.   PLoS Genetics

Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine

(2017) Chiranjib Chakraborty et al.   Molecular Therapy-Nucleic Acids

Exosomal microRNAs in giant panda (Ailuropoda melanoleuca) breast milk: potential maternal regulators for the development of newborn cubs

(2017) Jideng Ma et al.   Scientific Reports

Detection of dietetically absorbed maize-derived microRNAs in pigs

(2017) Yi Luo et al.   Scientific Reports

Cross-kingdom inhibition of breast cancer growth by plant miR159

(2016) Andrew R Chin et al.   CELL RESEARCH

Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution

(2016) Marta Mauri et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs in Honey Bee Caste Determination

(2016) Regan Ashby et al.   Scientific Reports

Plant microRNAs as novel immunomodulatory agents

(2016) Duccio Cavalieri et al.   Scientific Reports

Differential expression of miRNAs related to caste differentiation in the honey bee, Apis mellifera

(2015) Xiangqian Guo et al.   APIDOLOGIE

A novel chemopreventive strategy based on therapeutic microRNAs produced in plants

(2015) Sizolwenkosi Mlotshwa et al.   CELL RESEARCH

Detection of dietary plant-based small RNAs in animals

(2015) Jian Yang et al.   CELL RESEARCH

Plant miRNAs: biogenesis, organization and origins

(2015) Hikmet Budak et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

Bovine milk exosomes contain microRNA and mRNA and are taken up by human macrophages

(2015) Hirohisa Izumi et al.   JOURNAL OF DAIRY SCIENCE

Effective detection and quantification of dietetically absorbed plant microRNAs in human plasma

(2015) Hongwei Liang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA

(2015) Gaspare La Rocca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonfunctional ingestion of plant miRNAs in silkworm revealed by digital droplet PCR and transcriptome analysis

(2015) Ling Jia et al.   Scientific Reports

Commercial Cow Milk Contains Physically Stable Extracellular Vesicles Expressing Immunoregulatory TGF-β

(2015) Bartijn C. H. Pieters et al.   PLoS One

Detection of an Abundant Plant-Based Small RNA in Healthy Consumers

(2015) Jian Yang et al.   PLoS One

Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses

(2014) Zhen Zhou et al.   CELL RESEARCH

Development of microRNA therapeutics is coming of age

(2014) E. van Rooij et al.   EMBO Molecular Medicine

Cnidarian microRNAs frequently regulate targets by cleavage

(2014) Y. Moran et al.   GENOME RESEARCH

Interspecies communication between plant and mouse gut host cells through edible plant derived exosome-like nanoparticles

(2014) Jingyao Mu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Regulation of microRNA biogenesis

(2014) Minju Ha et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Time-Dependent Expression Profiles of microRNAs and mRNAs in Rat Milk Whey

(2014) Hirohisa Izumi et al.   PLoS One

Drug target miRNAs: chances and challenges

(2014) Marco F. Schmidt   TRENDS IN BIOTECHNOLOGY

Grape Exosome-like Nanoparticles Induce Intestinal Stem Cells and Protect Mice From DSS-Induced Colitis

(2013) Songwen Ju et al.   MOLECULAR THERAPY

Lack of detectable oral bioavailability of plant microRNAs after feeding in mice

(2013) Brent Dickinson et al.   NATURE BIOTECHNOLOGY

Biogenesis, Turnover, and Mode of Action of Plant MicroRNAs

(2013) K. Rogers et al.   PLANT CELL

Transcriptome Profiling of microRNA by Next-Gen Deep Sequencing Reveals Known and Novel miRNA Species in the Lipid Fraction of Human Breast Milk

(2013) Erika M. Munch et al.   PLoS One

Recipe for a Busy Bee: MicroRNAs in Honey Bee Caste Determination

(2013) Xiangqian Guo et al.   PLoS One

Real-time quantitative PCR and droplet digital PCR for plant miRNAs in mammalian blood provide little evidence for general uptake of dietary miRNAs

(2013) Kenneth W. Witwer et al.   RNA Biology

Ineffective delivery of diet-derived microRNAs to recipient animal organisms

(2013) Jonathan W. Snow et al.   RNA Biology

Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

(2012) Alexander V. Vlassov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Large-scale analysis of microRNA evolution

(2012) José Guerra-Assunção et al.   BMC GENOMICS

Next-generation small RNA sequencing for microRNAs profiling in Apis mellifera: comparison between nurses and foragers

(2012) F. Liu et al.   INSECT MOLECULAR BIOLOGY

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors

(2012) Jun Xie et al.   NATURE METHODS

The Complex Exogenous RNA Spectra in Human Plasma: An Interface with Human Gut Biota?

(2012) Kai Wang et al.   PLoS One

Alternative RISC assembly: Binding and repression of microRNA-mRNA duplexes by human Ago proteins

(2012) M. M. Janas et al.   RNA

Role of miRNAs and siRNAs in biotic and abiotic stress responses of plants

(2011) Basel Khraiwesh et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

(2011) Lin Zhang et al.   CELL RESEARCH

Target-Mediated Protection of Endogenous MicroRNAs in C. elegans

(2011) Saibal Chatterjee et al.   DEVELOPMENTAL CELL

Chemical modification and design of anti-miRNA oligonucleotides

(2011) K A Lennox et al.   GENE THERAPY

microRNA Replacement Therapy for Cancer

(2011) Jon C. Henry et al.   PHARMACEUTICAL RESEARCH

MapMi: automated mapping of microRNA loci

(2010) Jose Afonso Guerra-Assuncao et al.   BMC BIOINFORMATICS

An endogenous, systemic RNAi pathway in plants

(2010) Patrice Dunoyer et al.   EMBO JOURNAL

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

(2010) H. R. Chiang et al.   GENES & DEVELOPMENT

Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence

(2010) E. Berezikov et al.   GENOME RESEARCH

Target RNA-Directed Trimming and Tailing of Small Silencing RNAs

(2010) S. L. Ameres et al.   SCIENCE

Origin, Biogenesis, and Activity of Plant MicroRNAs

(2009) Olivier Voinnet   CELL

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Active turnover modulates mature microRNA activity in Caenorhabditis elegans

(2009) Saibal Chatterjee et al.   NATURE

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Expanded RNA-binding activities of mammalian Argonaute 2

(2009) Grace S. Tan et al.   NUCLEIC ACIDS RESEARCH

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

(2008) Yanli Wang et al.   NATURE

Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals

(2008) Andrew Grimson et al.   NATURE

MicroRNAs and the advent of vertebrate morphological complexity

(2008) A. M. Heimberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of Jasmonate Biosynthesis and Senescence by miR319 Targets

(2008) Carla Schommer et al.   PLOS BIOLOGY

Differentiating Protein-Coding and Noncoding RNA: Challenges and Ambiguities

(2008) Marcel E. Dinger et al.   PLoS Computational Biology