PL-S2, a homogeneous polysaccharide from Radix Puerariae lobatae, attenuates hyperlipidemia via farnesoid X receptor (FXR) pathway-modulated bile acid metabolism

Dysregulated FXR-FGF19 Signaling and Choline Metabolism is Associated with Gut Dysbiosis and Hyperplasia in a Novel Pig Model of Pediatric NASH

(2020) Gabriella V. Hernandez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Geniposide reduces cholesterol accumulation and increases its excretion by regulating the FXR-mediated liver-gut crosstalk of bile acids

(2020) Jinxin Liu et al.   PHARMACOLOGICAL RESEARCH

Reading and interpreting reviews for health professionals: a practical review

(2020) Michele Antonelli et al.   Internal and Emergency Medicine

Comparison of the Extraction Efficiency of Isoflavone Compounds from Puerariae lobatae by Ionic Liquids with 11 Anions and 8 Imidazolium-Based Cations

(2020) Yan Cheng et al.   ACS Omega

Purification, structural elucidation and physicochemical properties of a polysaccharide from Abelmoschus esculentus L (okra) flowers

(2020) Weijie Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Isolation and purification of acidic polysaccharides from Agaricus blazei Murill and evaluation of their lipid-lowering mechanism

(2020) Yuxin Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

IL-17A-producing γδ T cells promote liver pathology in acute murine schistosomiasis

(2020) Lei Sun et al.   Parasites & Vectors

Evaluating the Utility of Permethylated Polysaccharide Solution NMR Data for Characterization of Insoluble Plant Cell Wall Polysaccharides

(2020) Ikenna E. Ndukwe et al.   ANALYTICAL CHEMISTRY

Effects of polysaccharide from Pueraria lobata on gut microbiota in mice

(2020) Rong Chen et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

GC–MS-based metabolomics research on the anti-hyperlipidaemic activity of Prunella vulgaris L. polysaccharides

(2020) Zhimin Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Sulfated polysaccharide from the red algae Gelidiella acerosa: Anticoagulant, antiplatelet and antithrombotic effects

(2020) Francisco Diêgo da Silva Chagas et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Lycium ruthenicum Murr polysaccharide protects cortical neurons against oxygen-glucose deprivation/reperfusion in neonatal hypoxic-ischemic encephalopathy

(2020) Kewei Deng et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Rapid determination of polysaccharides and antioxidant activity of Poria cocos using near-infrared spectroscopy combined with chemometrics

(2020) Yuan Yi et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters

(2019) Lulu Sun et al.   Acta Pharmaceutica Sinica B

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

(2019) Emelia J. Benjamin et al.   CIRCULATION

A systematic investigation of the effects of long-term administration of a high-fat diet on drug transporters in the mouse liver, kidney and intestine

(2019) Xianyuan Lu et al.   CURRENT DRUG METABOLISM

Probiotic LGG prevents liver fibrosis through inhibiting hepatic bile acid synthesis and enhancing bile acid excretion in mice

(2019) Yunhuan Liu et al.   HEPATOLOGY

Hepatic cholesterol accumulation ascribed to the activation of ileum Fxr-Fgf15 pathway inhibiting hepatic Cyp7a1 in high-fat diet-induced obesity rats

(2019) Yingting Duan et al.   LIFE SCIENCES

Colesevelam enhances the beneficial effects of brown fat activation on hyperlipidaemia and atherosclerosis development

(2019) Enchen Zhou et al.   CARDIOVASCULAR RESEARCH

Structural characterization and immunomodulatory activity of a novel polysaccharide from Pueraria lobata (Willd.) Ohwi root

(2019) Zhou Dong et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Moxibustion for treating patients with hyperlipidemia

(2019) Qin Yao et al.   MEDICINE

Polyphenol Effects on Cholesterol Metabolism via Bile Acid Biosynthesis, CYP7A1: A Review

(2019) Karen F. Chambers et al.   Nutrients

Mass spectrometry-based metabolomics approach to reveal differential compounds in pufferfish soups: Flavor, nutrition, and safety

(2019) Hongyan Bi et al.   FOOD CHEMISTRY

Extraction of high-amylose starch from Radix Puerariae using high-intensity low-frequency ultrasound

(2019) Yuanhui Li et al.   ULTRASONICS SONOCHEMISTRY

Metabolomics and 16S rRNA Gene Sequencing Analyses of Changes in the Intestinal Flora and Biomarkers Induced by Gastrodia-Uncaria Treatment in a Rat Model of Chronic Migraine

(2019) Zhiqi Wen et al.   Frontiers in Pharmacology

Cyp7a1 is continuously increased with disrupted Fxr-mediated feedback inhibition in hypercholesterolemic TALLYHO/Jng mice

(2018) Eun-Ah Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Study of soy-fortified green tea curd formulated using potential hypocholesterolemic and hypotensive probiotics isolated from locally made curd

(2018) Sahoo Moumita et al.   FOOD CHEMISTRY

Comparative Metabolomics Analysis of Cervicitis in Human Patients and a Phenol Mucilage-Induced Rat Model Using Liquid Chromatography Tandem Mass Spectrometry

(2018) Xiaoyong Zhang et al.   Frontiers in Pharmacology

Analyzing the hepatoprotective effect of the Swertia cincta Burkill extract against ANIT-induced cholestasis in rats by modulating the expression of transporters and metabolic enzymes

(2017) Lili Xu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Bile Salt Homeostasis in Normal and Bsep Gene Knockout Rats with Single and Repeated Doses of Troglitazone

(2017) Yaofeng Cheng et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Purification and characterization of a novel polysaccharide–peptide complex from Clinacanthus nutans Lindau leaves

(2016) Danmin Huang et al.   CARBOHYDRATE POLYMERS

Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice

(2016) Yang Xu et al.   HEPATOLOGY

Cholesterol-Lowering Effects and Mechanisms in View of Bile Acid Pathway of Resveratrol and Resveratrol Glucuronides

(2016) Dongyan Shao et al.   JOURNAL OF FOOD SCIENCE

Effects of Gegen (Puerariae lobatae Radix) water extract on improving detrusor overactivity in spontaneously hypertensive rats

(2016) Xuelin Zhou et al.   PHYTOMEDICINE

Structural characterization and anticoagulant activity of a sulfated polysaccharide from the green alga Codium divaricatum

(2015) Na Li et al.   CARBOHYDRATE POLYMERS

Bile Acids as Hormones: The FXR-FGF15/19 Pathway

(2015) Steven A. Kliewer et al.   DIGESTIVE DISEASES

Comparing morphological, chemical and anti-diabetic characteristics of Puerariae Lobatae Radix and Puerariae Thomsonii Radix

(2015) Ka H. Wong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Complement, a target for therapy in inflammatory and degenerative diseases

(2015) B. Paul Morgan et al.   NATURE REVIEWS DRUG DISCOVERY

The Fibroblast Growth Factor signaling pathway

(2015) David M. Ornitz et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Chemical studies on the polysaccharides of Salicornia brachiata

(2014) Naresh D. Sanandiya et al.   CARBOHYDRATE POLYMERS

Isolation, characterization and antioxidant activity of polysaccharide from Schisandra sphenanthera

(2014) Ting Zhao et al.   CARBOHYDRATE POLYMERS

Atomic force microscopy and force spectroscopy on the assessment of protein folding and functionality

(2012) Filomena A. Carvalho et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR

(2012) Anna C. Calkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Interference with Bile Salt Export Pump Function Is a Susceptibility Factor for Human Liver Injury in Drug Development

(2010) Ryan E. Morgan et al.   TOXICOLOGICAL SCIENCES

The membrane protein ATPase class I type 8B member 1 signals through protein kinase C zeta to activate the farnesoid X receptor

(2008) Tamara Frankenberg et al.   HEPATOLOGY