Advances in the Synthesis of Benzo‐Fused Spiro Nitrogen Heterocycles: New Approaches and Modification of Old Strategies

Rational Synthesis of 5,5,5‐tricyclic Fused Thia‐heptaphyrin (1.1.1.1.1.1.0) From a Helical Oligopyrrin Hybrid

(2020) Yating Fu et al.   Chemistry-An Asian Journal

Synthesis of spiro(indoline‐3,1′‐pyrazolo[1,2‐ a ]pyrazoles) by 1,3‐dipolar cycloadditions of isatin N , N ′‐cyclic azomethine imines with alkynes

(2020) Yang Shi et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Three‐component electrosynthesis of spirooxindole‐pyran derivatives through a simple and efficient method

(2020) Somayeh Makarem   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis of (1′ S *,2 R *,3 R *)‐ and (1′ S *,2 R *,3 S *)‐ N ‐arylsulfonyl‐2‐(1′‐halogenethyl)‐3‐methylindolines and their selective toxicity against SH‐SY5Y cell line

(2020) Rail R. Gataullin et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Regioselectivity of (3+2) cycloaddition of azomethine ylides to activated olefins in the synthesis of spiro[oxindole-3,2′-pyrrolidine] derivatives

(2020) Alexei N. Izmest’ev et al.   Chemistry of Heterocyclic Compounds

Visible‐Light‐Promoted Selenylative Spirocyclization of Indolyl‐ynones toward the Formation of 3‐Selenospiroindolenine Anticancer Agents

(2020) Xiu‐Jie Zhou et al.   Chemistry-An Asian Journal

3-(2-Isocyanoethyl)indole: A Versatile Reagent for Polycyclic Spiroindoline Synthesis

(2020) Guo-Shu Chen et al.   SYNLETT

A Facile L‐Proline Catalyzed One‐Pot Synthesis of Xanthene and Acridine Based Quinolones via Knoevenagel Condensation Reaction

(2020) Manne Madhava Reddy et al.   ChemistrySelect

NHC-Catalyzed Generation of α,β-Unsaturated Acylazoliums for the Enantioselective Synthesis of Heterocycles and Carbocycles

(2019) Santigopal Mondal et al.   ACCOUNTS OF CHEMICAL RESEARCH

Organocatalyzed Dearomative Cycloaddition of 2-Nitrobenzofurans and Isatin-Derived Morita–Baylis–Hillman Carbonates: Highly Stereoselective Construction of Cyclopenta[b]benzofuran Scaffolds

(2019) Jian-Qiang Zhao et al.   ORGANIC LETTERS

Manganese-Catalyzed Asymmetric Oxidation of Methylene C–H of Spirocyclic Oxindoles and Dihydroquinolinones with Hydrogen Peroxide

(2019) Bin Qiu et al.   ORGANIC LETTERS

Multicomponent domino protocol for the stereoselective synthesis of novel pyrrolo[3,2–c]quinolinone hybrid heterocycles

(2019) Natarajan Arumugam et al.   TETRAHEDRON LETTERS

Four-Component Regio- and Diastereoselective Synthesis of Pyrrolizidines Incorporating Spiro-Oxindole/Indanedione via 1,3-Dipolar Cycloaddition Reaction of Azomethine Ylides

(2019) Abdolali Alizadeh et al.   ChemistrySelect

Rapid Oxidation of the Hole Transport Layer in Perovskite Solar Cells by A Low-Temperature Plasma

(2019) Yumeng Wang et al.   Scientific Reports

Asymmetric Synthesis of Vicinally Bis(trifluoromethyl)-Substituted 3,3′-Pyrrolidinyl Spirooxindoles via Organocatalytic 1,3-Dipolar Cycloaddition Reactions

(2019) Ning Lin et al.   SYNTHESIS-STUTTGART

Similar or different: the same Spiro-core but different alkyl chains with apparently improved device performance of perovskite solar cells

(2019) Fan Liu et al.   Science China-Chemistry

Gold-Catalyzed Cascade Reactions of 4H-Furo[3,2-b]indoles with Allenamides: Synthesis of Indolin-3-one Derivatives

(2019) Valentina Pirovano et al.   JOURNAL OF ORGANIC CHEMISTRY

Discovery of novel glycerolated quinazolinones from Streptomyces sp. MBT27

(2019) Nataliia V. Machushynets et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Synthesis of Spiropyrazolines via a Pseudo-Six Component Reaction

(2019) Atieh Rezvanian et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Hypervalent Iodine-Mediated Cyclization of Homotryptamine Derivatives

(2019) Xinpeng Jiang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Asymmetric Synthesis of Bridged O,O-Ketals with Spirooxindole Motif

(2019) Megha Balha et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Spirooxindole-pyrrolidine heterocyclic hybrids promotes apoptosis through activation of caspase-3

(2019) Raju Suresh Kumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design and synthesis of new substituted spirooxindoles as potential inhibitors of the MDM2–p53 interaction

(2019) Assem Barakat et al.   BIOORGANIC CHEMISTRY

Synthesis of Spirooxindole Oxetanes via a Domino Reaction of 3-Hydroxyoxindoles and Phenyl Vinyl Selenone

(2019) Martina Palomba et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Efficient green synthesis of antioxidant azacoumarin dye bearing spiro-pyrrolidine for enhancing electro-optical properties of perovskite solar cells

(2019) S.K. Attia et al.   JOURNAL OF MOLECULAR STRUCTURE

Sequential Assembly of Morita–Baylis–Hillman Carbonates and Activated ortho-Vinylbenzaldehydes To Construct Chiral Methanobenzo[7]annulenone Frameworks

(2019) Bo Jiang et al.   ORGANIC LETTERS

Synthesis of Bridged Biaryl Atropisomers via Sequential Cu- and Pd-Catalyzed Asymmetric Ring Opening and Cyclization

(2019) Xiaoping Xue et al.   ORGANIC LETTERS

An efficient protocol for the synthesis of spiroindenoquinoxaline derivatives using novel NiFe2O4/Ag3PO4 as a nano magnetically heterogeneous catalyst

(2019) Narges Hosseini Nasab et al.   POLYHEDRON

Manganese(III)-Based Oxidative Cyclization of N-Aryl-2-oxocyclo­alkane-1-carboxamides: Synthesis of Spiroindolinones

(2019) Shintaro Katayama et al.   SYNTHESIS-STUTTGART

Sodium Formate-Catalyzed One-Pot Synthesis of Functionalized Spiro[indoline-3,5′-pyrido[2,3-d ]pyrimidine]/Spiro[acenaphthylene-1,5′-pyrido[2,3-d ]-pyrimidine] Derivatives

(2019) Khondekar Nurjamal et al.   ChemistrySelect

An Efficient Ultrasound Promoted Three‐Component and Regioselective Synthesis of Indenoquinoxaline Compounds Containing Pyrrolopyrimidine Skeleton

(2019) Abdolali Alizadeh et al.   ChemistrySelect

TFAA‐Catalyzed Annulation Synthesis of Spiro Pyrrolo[1,2‐ a ]quinoxaline Derivatives from 1‐(2‐Aminophenyl)pyrroles and Benzoquinones/Ketones

(2019) Jixiang Ni et al.   Chemistry-An Asian Journal

Copper-Catalyzed Dimerization of Sulfoxonium Ylides with 3-Diazoindolin-2-imines: A Practical and Efficient Approach to Spiro[cyclopropane-1,3′-indolin]-2′-imines

(2019) Muhammad Suleman et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Visible-Light-Induced Ring-Opening of Hydrogenolysis Spirocyclopropyl Oxindoles Through Photoredox Catalysis

(2019) Zhi-Ping Liu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Cycloaddition Reactions of Oxindole α-Keto Esters via Cascade Dienamine-Enamine and Trienamine Strategies

(2019) Subramaniam Muthusamy et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

An Efficient and Easy Method for the One‐pot Synthesis of Spirooxindoles in the Presence of Na 2 CO 3

(2019) Khadhar Navaz Umar Basha et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis of spiro-fused heterocycles under aerobic conditions by using polymer gel-entrapped catalyst

(2019) Audumbar Patil et al.   RESEARCH ON CHEMICAL INTERMEDIATES

One-pot multicomponent construction of chromanone-fused pyrrolidinyl spirooxindole collections through a decarboxylative 1,3-dipolar [3 + 2] cycloaddition reaction

(2019) Shuang Chen et al.   SYNTHETIC COMMUNICATIONS

Synthetic and Mechanistic Studies into the Rearrangement of Spirocyclic Indolenines into Quinolines

(2019) Ryan G. Epton et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Asymmetric Michael/Dieckmann Cyclization Reaction of Alkynones To Construct Spirocyclopentene Oxindoles

(2019) Jiawen Lang et al.   ORGANIC LETTERS

Double Thiol-Chiral Brønsted Base Catalysis: Asymmetric Cross Rauhut–Currier Reaction and Sequential [4 + 2] Annulation for Assembly of Different Activated Olefins

(2019) Zhi Zhou et al.   ORGANIC LETTERS

Three-Component Spiro Heterocyclization of Pyrrolediones with Aminoindenones. Synthesis of Spiro[diindeno[1,2-b:2′,1′-e]pyridine-11,3′-pyrroles]

(2019) D. I. Antonov et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

CF3COOH/O2-Mediated Metal-Free Domino Construction of the Isatin Skeleton

(2019) Jiadi Zhou et al.   SYNLETT

Synthesis of dispiro[1-benzothiophene-2,3'-pyrrolidine-2',3”-indoline]-2”,3-diones in cycloaddition reaction

(2019) Ying Zhou et al.   Chemistry of Heterocyclic Compounds

Regioselective synthesis of spiro isoxazole‐oxindole‐tetrahydrothiophene hybrids via cascade reactions under catalyst‐free conditions

(2019) Sakkani Nagaraju et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Regioselective synthesis and biological evaluation of novel dispiropyrrolidine derivatives via one-pot four-component reaction

(2019) Subramanya Gopal Hegde et al.   SYNTHETIC COMMUNICATIONS

Highly efficient green synthesis of the photochromic spironaphthoxazines using an eco-friendly choline hydroxide catalyst

(2019) Shailesh N. Vajekar et al.   SYNTHETIC COMMUNICATIONS

An anti‐Michael route for the synthesis of indole‐spiro (indene‐pyrrolidine) by 1,3‐cycloaddition of azomethineylide with indole‐derivatised olefins

(2019) Shivaraj Yellappa   JOURNAL OF HETEROCYCLIC CHEMISTRY

CsF promoted rapid synthesis of spirooxindole‐pyran annulated heterocycles at room temperature in ethanol

(2019) Yogesh B. Wagh et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Regio- and Diastereoselective Synthesis of Novel Polycyclic Pyrrolo[2,1-a]isoquinolines Bearing Indeno[1,2-b]quinoxaline Moieties by a Three-Component [3+2]-Cycloaddition Reaction

(2019) Firouz Matloubi Moghaddam et al.   SYNLETT

Synthesis of spirooxindole analogues from 2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde

(2019) Venkata Nookaapparao Gorli et al.   SYNTHETIC COMMUNICATIONS

Enantioselective Synthesis of the Spirotropanyl Oxindole Scaffold through Bimetallic Relay Catalysis

(2018) Zhi-Jun Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Domino Pd0-Catalyzed C(sp3)-H Arylation/Electrocyclic Reactions via Benzazetidine Intermediates

(2018) Ronan Rocaboy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New thiophene-acridine compounds: Synthesis, antileishmanial activity, DNA binding, chemometric, and molecular docking studies

(2018) Vanessa de Lima Serafim et al.   Chemical Biology & Drug Design

An atmosphere and light tuned highly diastereoselective synthesis of cyclobuta/penta[b]indoles from aniline-tethered alkylidenecyclopropanes with alkynes

(2018) Bo Cao et al.   CHEMICAL COMMUNICATIONS

Synthesis of 1H-pyrrol-2(5H)-ones (microreview)

(2018) Seyed Sajad Sajadikhah   Chemistry of Heterocyclic Compounds

Recent advances in the synthesis and reactivity of spiro-epoxyoxindoles

(2018) Serena Monticelli et al.   Chemistry of Heterocyclic Compounds

Synthesis and Biological Activities of 1-Azaaurone Derivatives

(2018) Min Zhang et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis of spiro[pyrazoloquinoline-oxindoles] and spiro[chromenopyrazolo-oxindoles] promoted by guanidine-functionalized magnetic Fe3O4 nanoparticles

(2018) Fatemeh Alemi Tameh et al.   Journal of the Iranian Chemical Society

Preparation and Gas Separation Properties of Spirobichroman-Based Polyimides

(2018) Caili Zhang et al.   MACROMOLECULAR CHEMISTRY AND PHYSICS

Synthesis of spiro compounds based on 1H-pyrrole-2,3-diones

(2018) Konovalova Valeriya et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

Synthesis of 1′-tetrazolylmethyl-spiro[pyrrolidine-3,3′-oxindoles] via two coupled one-pot processes Ugi-azide/Pictet–Spengler and oxidative spiro-rearrangement

(2018) Nancy V. Alvarez-Rodríguez et al.   NEW JOURNAL OF CHEMISTRY

Low-cost synthesis of heterocyclic spiro-type hole transporting materials for perovskite solar cell applications

(2018) Venkatesan Govindan et al.   NEW JOURNAL OF CHEMISTRY

A comparative study of the effects of terminal aromatic moieties in spirobifluorene core-based diketopyrrolopyrrole non-fullerene acceptors

(2018) Zhi-Cai Chen et al.   NEW JOURNAL OF CHEMISTRY

A facile and efficient procedure for one-pot four-component synthesis of polysubstituted spiro pyrano[2,3-c]pyrazole and spiro 1,4-dihydropyridine catalyzed by a Dabco-based ionic liquid under mild conditions

(2018) Tong Liu et al.   NEW JOURNAL OF CHEMISTRY

Synthesis of New Spiro Pyrrole/Pyrrolizine/Thiazole Derivatives via (3+2) Cycloaddition Reaction

(2018) Pravin R. Likhar et al.   NEW JOURNAL OF CHEMISTRY

PhI(OAc)2-mediated dearomative C–N coupling: facile construction of the spiro[indoline-3,2′-pyrrolidine] skeleton

(2018) Yali Zhou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Divergent biosynthesis of indole alkaloids FR900452 and spiro-maremycins

(2018) Yingyi Duan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Divergent Synthesis of Oxindolylidene Acetates and Spirooxindolopyrrolidones from Arynes

(2018) Virat G. Pandya et al.   ORGANIC LETTERS

When Ethyl Isocyanoacetate Meets Isatins: A 1,3-Dipolar/Inverse 1,3-Dipolar/Olefination Reaction for Access to 3-Ylideneoxindoles

(2018) Wen-Kui Yuan et al.   ORGANIC LETTERS

Synthesis and Complex Formation of Rhodamine-Substituted Spirobenzopyranindolines

(2018) E. V. Solov’eva et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Exocyclic Double Bond in Benzo-Fused Nitrogen Heterocycles: Methods of Introduction and Syntheses with Its Participation

(2018) R. R. Gataullin   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Hydrolytic Degradation of Some Fused and Spiro Compounds Containing a System of 2-Amino-3-Cyano-4H-Pyran

(2018) A. N. Andin   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Divergent Reactivity of Indole-Tethered Ynones with Silver(I) and Gold(I) Catalysts: A Combined Synthetic and Computational Study

(2018) Jason Lynam et al.   SYNTHESIS-STUTTGART

Regio- and diastereoselective synthesis of anticancer spirooxindoles derived from tryptophan and histidine via three-component 1,3-dipolar cycloadditions in an ionic liquid

(2018) Natarajan Arumugam et al.   TETRAHEDRON

Trapping rhodium carbenoids with aminoalkynes for the synthesis of diverse N -heterocycles

(2018) Arianne C. Hunter et al.   TETRAHEDRON

An expeditious access of 2,5′-dioxo-5′,6′,7′,8′-tetrahydro-1′H-spiro[indoline-3,4′-quinoline]-3′-carboxylate by reaction of isatin, ethyl cyanoacetate and enaminone in water

(2018) Keshri Nath Tiwari et al.   TETRAHEDRON

Highly efficient construction of chiral dispirocyclic oxindole/thiobutyrolactam/chromanone complexes through Michael/cyclization cascade reactions with a rosin-based squaramide catalyst

(2018) Ning Lin et al.   TETRAHEDRON

One-pot, five-component 1,3-dipolar cycloaddition: A facile synthesis of spiropyrrolidine and spiropyrrolizidine derivatives

(2018) Ren Wen et al.   TETRAHEDRON LETTERS

One pot, three component 1,3 dipolar cycloaddition: Regio and diastereoselective synthesis of spiropyrrolidinyl indenoquinoxaline derivatives

(2018) Priyabrata Pattanaik et al.   TETRAHEDRON LETTERS

An expedient regio and diastereoselective synthesis of novel spiropyrrolidinylindenoquinoxalines via 1,3-dipolar cycloaddition reaction

(2018) Marri Sameer Reddy et al.   TETRAHEDRON LETTERS

Stereoselective synthesis of spiro[pyrrolidin-3,3′-oxindoles] via organocatalyzed asymmetric Mannich-type reaction

(2018) Hui Shao et al.   TETRAHEDRON LETTERS

Zn-Catalyzed Diastereo- and Enantioselective Dearomative [3+2] Cycloaddition Reaction of 2-Nitroindoles and 2-Nitrobenzothiophenes

(2018) Jian-Qiang Zhao et al.   ADVANCED SYNTHESIS & CATALYSIS

Cascade Formation of C3 -Unsymmetric Spirooxindoles via PhI(OAc)2 -Mediated Oxidative C−C/C−N Bond Formation

(2018) Jiyun Sun et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of novel spiro[chromeno[4′,3′:3,4]pyrazolo[1,2-b]phthalazine-7,3′-indoline]-2′,6,9,14-tetraone

(2018) Somaye Nikzad Shalkouhi et al.   Journal of the Iranian Chemical Society

Recent advances in the synthesis of cyclopropanes

(2018) Wanqing Wu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Spiro[indole-3,2′-pyrroles] from Pyrrolopyrazinetriones and Aminocyclohexenones

(2018) A. V. Chervyakov et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Catalyst-Free Three-Component Synthesis of Spirobenzimidazolidines Bearing an Indole Scaffold

(2018) F. Moghaddam et al.   SYNLETT

N-Heterocycle-Triggered MCRs: An Approach to the Concise Synthesis of Perfluoroalkylated Spiro-1,3-oxazines

(2018) Hui Zhang et al.   SYNTHESIS-STUTTGART

The rearrangement of 1H,1′H-spiro[quinoline-4,2′-quinoxaline]-2,3′ (3H,4′H)-diones – a new and efficient method for the synthesis of 4-(benzimidazol-2-yl)quinolin-2(1H)-ones

(2018) Vakhid A. Mamedov et al.   TETRAHEDRON

Reactivity of spiroanthraceneoxazolidines with cyclopropanes: An approach to the oxindole alkaloid scaffold

(2018) Evgeny M. Buev et al.   TETRAHEDRON LETTERS

Synthesis of dihydrobenzoxazine pyrrolidone spirocyclic compounds

(2018) Wenqin Liu et al.   TETRAHEDRON LETTERS

Copper-Catalyzed [3+2] Cycloaddition and Interrupted Fischer Indolization to Prepare Polycyclic Furo[2,3-b]indolines from N -Aryl Isatin Nitrones and Methylenecyclopropanes

(2018) Si-Yi Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Spiro[indoline‐3,4′‐pyrano[3,2‐ c ]chromene]diones

(2018) Sakineh Ghadiri et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Catalytic Asymmetric Ring-Opening/Cyclopropanation of Cyclic Sulfur Ylides: Construction of Sulfur-Containing Spirocyclopropyloxindoles with Three Vicinal Stereocenters

(2018) Hongjiang Mei et al.   ORGANIC LETTERS

Green metal-free synthesis of spiro-fused 3,4′-pyrazolo[4′,3′:5,6]pyrido[2,3-d]pyrimidine derivatives via deamination cyclization reactions in aqueous medium

(2018) Lei Dai et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Synthesis of Spiro[1,4-benzothiazine-2,2′-pyrroles] by Reaction of Pyrrolo[1,2-c][4,1]benzoxazepinetriones with 2-Aminobenzenethiol

(2018) A. A. Maslivets et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Catalyst-Free Synthesis of Aminals from Indole-Derived α,α-Di­cyanoolefins

(2018) Hai-Lei Cui et al.   SYNLETT

Utilization of 1H-Indole-3-carboxaldehyde as a Precursor for the Synthesis of Bioactive Indole Alkaloids

(2018) Gilbert Kirsch et al.   SYNTHESIS-STUTTGART

Concise Synthesis of Tryptanthrin Spiro Analogues with In Vitro Antitumor Activity Based on One-Pot, Three-Component 1,3-Dipolar Cycloaddition of Azomethine Ylides to Сyclopropenes

(2018) Vitali Boitsov et al.   SYNTHESIS-STUTTGART

4-(N,N-Dimethylamino)pyridine (DMAP)-Catalyzed 1,3-Dipolar Cycloaddition of 3-Aminooxindole-Based Azomethine Ylides with α,β-Unsaturated Acyl Phosphonates for the Construction of Spiropyrrolidinyl-2,3′-oxindoles

(2018) Zhuo Chen et al.   SYNTHESIS-STUTTGART

Synthesis of Chiral 3-Substituted 3-Amino-2-oxindoles through Enantioselective Catalytic Domino and Tandem Reactions

(2018) Hélène Pellissier   SYNTHESIS-STUTTGART

Diastereospecific entry to pyrrolidinyldispirooxindole skeletons via three-component 1,3-dipolar cycloadditions

(2018) Yu-Lun Qian et al.   TETRAHEDRON

Synthesis of spiro-linked quinolinone-pyrrolidine/pyrrolo[1,2-c]thiazole-oxindole/acenaphthalene hybrids via multi-component [3 + 2] cycloaddition

(2018) Remani Vasudevan Sumesh et al.   TETRAHEDRON LETTERS

Cycloaddition of isatin-derived MBH carbonates and 3-methyleneoxindoles to construct diastereoselective cyclopentenyl bis-spirooxindoles and cyclopropyl spirooxindoles: Catalyst controlled [3 + 2] and [2 + 1] annulations

(2018) Prakash K. Warghude et al.   TETRAHEDRON LETTERS

Diversity-oriented one-pot multicomponent synthesis of chromanone-based 3,3′-pyrrolidinyl-spirooxindoles via a 1,3-dipolar cycloaddition reaction

(2018) Jing Yue et al.   TETRAHEDRON LETTERS

Merging π-Acid and Pd Catalysis: Dearomatizing Spirocyclization/Cross-Coupling Cascade Reactions of Alkyne-Tethered Aromatics

(2018) Hon Eong Ho et al.   ACS Catalysis

A catalyst-free 1,3-dipolar cycloaddition of C,N-cyclic azomethine imines and 3-nitroindoles: an easy access to five-ring-fused tetrahydroisoquinolines

(2017) Xihong Liu et al.   GREEN CHEMISTRY

Polyarylenediphthalides

(2017) Vladimir A Kraikin et al.   HIGH PERFORMANCE POLYMERS

α-Amino Acid Derived Benzimidazole-Linked Rhodamines: A Case of Substitution Effect at the Amino Acid Site toward Spiro Ring Opening for Selective Sensing of Al3+ Ions

(2017) Anupam Majumdar et al.   INORGANIC CHEMISTRY

Synthesis of New Spirooxindole-Fused Isoxazoline/Triazole and Isoxazoline/Isoxazole Derivatives from Three-Component 1,3-Dipolar Cycloaddition

(2017) Randa Sakly et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Catalyst-free Synthesis of Spiro[indoline-3,1′-pyrazolo[5,1-a]isoquinolines] via Diastereoselective 1,3-dipolar Cycloaddition under Mild Conditions

(2017) Fangzhi Hu et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Efficient catalytic application of a binary ionic liquid mixture in the synthesis of novel spiro[4H-pyridine-oxindoles]

(2017) Sorayya Yaghoubi Kalurazi et al.   NEW JOURNAL OF CHEMISTRY

Organocatalytic diastereoselective synthesis of spirooxindoles via [3+2] cycloadditions of azomethine ylides with α,β-unsaturated esters

(2017) Tibor Peňaška et al.   NEW JOURNAL OF CHEMISTRY

Quinine-Based Trifunctional Organocatalyst for Tandem Aza-Henry Reaction-Cyclization: Asymmetric Synthesis of Spiroxindole-Pyrrolidine/Piperidines

(2017) Saumen Hajra et al.   ORGANIC LETTERS

Rearrangement of an Intermediate Cyclopropyl Ketene in a RhII-Catalyzed Formal [4 + 1]-Cycloaddition Employing Vinyl Ketenes as 1,4-Dipoles and Donor–Acceptor Metallocarbenes

(2017) Kevin X. Rodriguez et al.   ORGANIC LETTERS

Spiroannulation of Oxindoles via Aryne and Alkyne Incorporation: Substituent-Diverted, Transition-Metal-Free, One-Pot Access to Spirooxindoles

(2017) Ramesh Samineni et al.   ORGANIC LETTERS

Synthesis and antimicrobial activity of fused isatin and diazepine derivatives derived from 2-acetyl benzofuran

(2017) R. Kenchappa et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Synthesis and complex formation of spirobenzopyranindolines containing rhodamine fragment

(2017) E. V. Solovyova et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

A facile synthesis of novel endo -selective polycyclic spiropyrrolidine oxindoles via 1,3-dipolar cycloaddition of α,γ-dialkylallenoate esters

(2017) Yingwei Wang et al.   TETRAHEDRON LETTERS

Regio- and stereoselective route to bis-[3-methyl-1,1′,4′-triaryl-5-oxo-spiro-pyrazoline-4,5′-pyrazoline] derivatives via 1,3-dipolar cycloaddition under sonication

(2017) Haider Behbehani et al.   Arabian Journal of Chemistry

Zinc triflate-mediated cyclopropanation of oxindoles with vinyl diphenyl sulfonium triflate: a mild reaction with broad functional group compatibility

(2017) Mingwei Zhou et al.   RSC Advances

Part I: Diastereoselective Reactions Involving β-Mono- and β,β′-Disubstituted Alkylidene Oxindoles: Pondering Alkene Geometry

(2017) Madhu Ganesh et al.   Asian Journal of Organic Chemistry

Synthesis of spiro[indoline-3,3′-pyrrolizines] by 1,3-dipolar reactions between isatins, L-proline and electron-deficient alkenes

(2017) Jairo Quiroga et al.   Acta Crystallographica Section C-Structural Chemistry

Sodium Iodide/Hydrogen Peroxide-Mediated Oxidation/Lactonization for the Construction of Spirocyclic Oxindole-Lactones

(2016) Guofeng Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Synthesis of Spirobenzazepinones with Atroposelectivity and Spiro-1,2-Diazepinones by NHC-Catalyzed [3+4] Annulation Reactions

(2016) Lei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of spiro[isoindole-1,5’-isoxazolidin]-3(2H)-ones as potential inhibitors of the MDM2-p53 interaction

(2016) Salvatore V Giofrè et al.   Beilstein Journal of Organic Chemistry

Design and optimization of (3-aryl-1 H -indazol-6-yl)spiro[cyclopropane-1,3′-indolin]-2′-ones as potent PLK4 inhibitors with oral antitumor efficacy

(2016) Sze-Wan Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Highly diastereoselective entry into chiral spirooxindole-based 4-methyleneazetidines via formal [2+2] annulation reaction

(2016) G. Rainoldi et al.   CHEMICAL COMMUNICATIONS

Highly Stereoselective [3+2] Cycloadditions of Chiral Palladium-ContainingN1-1,3-Dipoles: A Divergent Approach to Enantioenriched Spirooxindoles

(2016) Tian-Ren Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Hydrogen-Bonding Network Promoted [3+2] Cycloaddition: Asymmetric Catalytic Construction of Spiro-pseudoindoxyl Derivatives

(2016) Liang-Jie Zhang et al.   Chemistry-An Asian Journal

A Convenient 1,3-Dipolar Cycloaddition Reaction for the Synthesis of Spirooxindoles and Some Other Spirocompounds Containing the 1,3,4-Oxadiazole Moiety

(2016) Abdolali Alizadeh et al.   HELVETICA CHIMICA ACTA

Anti-inflammatory Activity of Two New Indole Alkaloids from the Stems ofNauclea officinalis

(2016) De-Li Chen et al.   HELVETICA CHIMICA ACTA

An Organocatalytic Asymmetric Diels-Alder Strategy for the Enantioselective Synthesis of Spirocyclic Oxindole-Cyclohexenones

(2016) Hiyoshizo Kotsuki et al.   HETEROCYCLES

Novel and one-pot Synthesis of Tetrahydropyrrolo[1,2-a ]-2-Methylbenzothiazole-3-Spiro-1′ -Cyclohexa-2′ ,5′ -Dien-4′ -one-4,5-Dicarboxylate Derivatives via a Three Component Reaction

(2016) F. J. Milani et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Electrocatalytic Multicomponent Reaction for Synthesis of Nanoparticles of Spirooxindole Derivatives from Isatins, Malononitrile, and Dimedone

(2016) Zahra Mohammad Darvish et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Synthesis and biological evaluation of new spirooxindoles with embedded pharmacophores

(2016) Sadasivam Mathusalini et al.   NEW JOURNAL OF CHEMISTRY

Pd-catalyzed cascade allylic alkylation and dearomatization reactions of indoles with vinyloxirane

(2016) Run-Duo Gao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

DABCO-catalyzed unusual [4 + 2] cycloaddition reaction: non-substituted allenoate acts as a four-carbon synthon and facile synthesis of spirooxindoles

(2016) Yufen Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Stereoselective Synthesis of Alkylidene Phthalides

(2016) Andrei Dragan et al.   ORGANIC LETTERS

Preparation and Reactions of Indoleninyl Halides: Scaffolds for the Synthesis of Spirocyclic Indole Derivatives

(2016) John T. R. Liddon et al.   ORGANIC LETTERS

Synthesis of new substituted acetamide derivatives of 6′,7′-dimethoxy-2′,3′-dihydro-1′H-spiro[isoquinoline-1,4′-cyclopentane]-1′-carboxamide

(2016) A. A. Aghekyan et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of new heterocyclic systems—substituted spiro[chromene-4,3′-indoles] and spiro[indole-3,4′-quinolines]

(2016) S. A. Pogosyan et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Recyclization of 5′-acetyl-2′-amino-6′-methyl-2-oxo-1,2-dihydrospiro[indole-3,4′-pyran]-3′-carbonitrile in reactions with some nitrogen binucleophiles

(2016) A. V. Andina et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Efficient Synthesis of Spirooxindole-Fused 3-Thiazoline Derivatives by a One-Pot Asinger-Type Reaction

(2016) Alessandra Silvani et al.   SYNLETT

Palladium-Catalyzed Nitration of Arenes by 1,2,3-Triazole-Directed C–H Activation

(2016) Yubo Jiang et al.   SYNTHESIS-STUTTGART

Regioselective Michael Addition of Anthrone to Methylene­indolinones

(2016) Liang Wang et al.   SYNTHESIS-STUTTGART

Rh2(OAc)4 catalyzed highly diastereoselective synthesis of 2,4,5-triaryl-1,3-oxazolidines and spirooxindolyl oxazolidines

(2016) Tamilselvan Rajasekaran et al.   TETRAHEDRON

Highly regio- and stereoselective 1,3-dipolar cycloaddition of stabilised azomethine ylides to 3,3,3-trihalogeno-1-nitropropenes: synthesis of trihalomethylated spiro[indoline-3,2′-pyrrolidin]-2-ones and spiro[indoline-3,3′-pyrrolizin]-2-ones

(2016) Alexey Yu. Barkov et al.   TETRAHEDRON

A highly stereoselective, catalytic four-component synthesis of dispiroindolo-pyrrolidines/-imidazolidines via azomethine ylides

(2016) Sengodagounder Muthusamy et al.   TETRAHEDRON

Highly efficient synthesis of enantioenriched fully-substituted spirocyclohexane oxindoles via a Michael-Michael-aldol cascade reaction

(2016) Qiang-Sheng Sun et al.   TETRAHEDRON LETTERS

NHC-Catalyzed Enantioselective Dearomatizing Hydroacylation of Benzofurans and Benzothiophenes for the Synthesis of Spirocycles

(2016) Daniel Janssen-Müller et al.   ACS Catalysis

One-pot green synthesis of biologically relevant novel spiro[indolin-2-one-3,4′-pyrano[2,3-c]pyrazoles] and studies on their spectral and X-ray crystallographic behaviors

(2016) Sakshi Sharma et al.   Acta Crystallographica Section B-Structural Science Crystal Engineering and Materials

Palladium(0)-Catalyzed Iminohalogenation of Alkenes: Synthesis of 2-Halomethyl Dihydropyrroles and Mechanistic Insights into the Alkyl Halide Bond Formation

(2015) Chen Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Synthesis of N-Heterocycles by Catalyst-Controlled, Activity-Directed Tandem Annulation of Diazo Compounds with Amino Alkynes

(2015) Kai Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sulfamic acid promoted one-pot three-component synthesis and cytotoxic evaluation of spirooxindoles

(2015) Ahmed Kamal et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Stability enhancement of fluorophores for lighting up practical application in bioimaging

(2015) Xumeng Wu et al.   CHEMICAL SOCIETY REVIEWS

Small molecule-based ratiometric fluorescence probes for cations, anions, and biomolecules

(2015) Min Hee Lee et al.   CHEMICAL SOCIETY REVIEWS

Furan's Gambit: Electrophile-Attack-Triggered Sacrifice of Furan Rings for the Intramolecular Construction of Azaheterocycles

(2015) Igor V. Trushkov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Cottoquinazolines E and F fromNeosartorya fischeriNRRL 181

(2015) Wei-Guang Shan et al.   HELVETICA CHIMICA ACTA

An Efficient Synthesis of Spiro-oxindole Derivatives by Three-Component Reactions in Water

(2015) Abdolali Alizadeh et al.   HELVETICA CHIMICA ACTA

Synthesis of spiro[indoline-3,4′-pyrano[2,3-c]pyrazole] and spiro[indoline-3,4′-pyrano[2,3-c]chromene] derivatives using silica-bonded ionic liquids as a recyclable catalyst in aqueous medium

(2015) Khodabakhsh Niknam et al.   Journal of the Iranian Chemical Society

New efficient fused-ring spiro[benzoanthracene-fluorene] dopant materials for blue fluorescent organic light-emitting diodes

(2015) Jae-Ryung Cha et al.   NEW JOURNAL OF CHEMISTRY

Diverse synthesis of natural product inspired fused and spiro-heterocyclic scaffolds via ring distortion and ring construction strategies

(2015) Chandramohan Bathula et al.   NEW JOURNAL OF CHEMISTRY

Construction of dispirocyclohexanes via amine-catalyzed [2 + 2 + 2] annulations of Morita–Baylis–Hillman acetates with exocyclic alkenes

(2015) Rongshun Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Facile synthesis of spirooxindole-pyrazolines and spirobenzofuranone-pyrazolines and their fungicidal activity

(2015) Changjiang Yang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Convenient synthesis of functionalized spiro[indoline-3,2′-pyrrolizines] or spiro[indoline-3,3′-pyrrolidines] via multicomponent reactions

(2015) Jing Sun et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

One-pot three components synthesis of novel 2-iminoquinazolines and 2-imino spiro[indoline-quinazoline/pyrimidine]ones catalyzed by sodium fluoride

(2015) Hassan Kefayati et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Synthesis of new spiro compounds proceeding from 11H-Indeno[1,2-b]quinoxalin-2-one

(2015) A. V. Velikorodov et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 2-propanol derivatives of N-methyl-6′,7′-dimethoxy-2′,3′-dihydro-1′H-spiro[cyclopentan-1,4′-isoquinoline]-1′-carboxamide

(2015) A. A. Aghekyan et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Rhodamine-chloronicotinaldehyde-based “OFF–ON” chemosensor for the colorimetric and fluorescent determination of Al3+ ions

(2015) Jong Woo Jeong et al.   SENSORS AND ACTUATORS B-CHEMICAL

Recent Advances in Organocatalytic Cascade Reactions toward the Formation of Quaternary Stereocenters

(2015) Tecla Gasperi et al.   SYNTHESIS-STUTTGART

Diastereoselective synthesis of spirooxindole derivatives via biocatalytic domino reaction

(2015) Yi-Ru Liang et al.   TETRAHEDRON

Polar [3+2] cycloaddition of isatin-3-imines with electrophilically activated heteroaromatic N-ylides: Synthesis of spirocyclic imidazo[1,2-a]pyridine and isoquinoline derivatives

(2015) Tayebeh Sattaei Mokhtari et al.   Arabian Journal of Chemistry

Organocatalytic Asymmetric Vinylogous Michael Addition of 3-(2-Oxoindolin-3-ylidene)butanoates to Nitroalkenes Catalyzed by a Bifunctional Cinchona-Based Squaramide

(2015) Chen Zheng et al.   Asian Journal of Organic Chemistry

Diverse Applications of Nitrones for the Synthesis of Heterocyclic Compounds

(2015) Laura L. Anderson   Asian Journal of Organic Chemistry

Oxidation reactions of azines: XIII. Synthesis, molecular structure, and oxidation reactions of 3-methyl-3,3′,4,4′,5,6-hexahydro-1′H,2H-spiro[benzo[f]isoquinoline-1,2′-naphthalen]-1′-one

(2015) A. V. Malkova et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Catalytic Enantioselective 1,3-Dipolar Cycloadditions of Azomethine Ylides for Biology-Oriented Synthesis

(2014) Rishikesh Narayan et al.   ACCOUNTS OF CHEMICAL RESEARCH

N-Heterocyclic Carbene Catalyzed Formal [3+2] Annulation Reaction of Enals: An Efficient Enantioselective Access to Spiro-Heterocycles

(2014) Chang Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly diastereo- and enantioselective construction of a spiro[cyclopenta[b]indole-1,3′-oxindole] scaffold via catalytic asymmetric formal [3+2] cycloadditions

(2014) Wei Tan et al.   CHEMICAL COMMUNICATIONS

Metal Complex Catalysis in the Synthesis of Spirocarbocycles

(2014) Vladimir A. D’yakonov et al.   CHEMICAL REVIEWS

Four-Membered Ring-Containing Spirocycles: Synthetic Strategies and Opportunities

(2014) Erick M. Carreira et al.   CHEMICAL REVIEWS

Iodine-Catalyzed Synthesis of Spiro[1,3,4-benzotriazepine-2,3′-indole]-2′,5(1H,1′H)-diones under Mild Conditions

(2014) Abdolali Alizadeh et al.   HELVETICA CHIMICA ACTA

The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1R,2S)-2-(3-((E)-4-(((cis)-2,6-Dimethylmorpholino)methyl)styryl)-1H-indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent

(2014) Peter B. Sampson et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3′[3H]indol]-2′(1′H)-ones as Orally Bioavailable Antitumor Agents

(2014) Peter B. Sampson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Silver-Catalyzed Tandem Hydroamination/Hydroarylation of 1-(2-Allylamino)phenyl-4-hydroxy-but-2-yn-1-ones to 1′-Allylspiro[indene-1,2′-indolin]-3′-ones

(2014) Srinivasa Reddy Mothe et al.   ORGANIC LETTERS

The Concise Synthesis of Spiro-Cyclopropane Compounds via the Dearomatization of Indole Derivatives

(2014) Jing Luo et al.   ORGANIC LETTERS

Biochemical and pharmacological characterization of isatin and its derivatives: from structure to activity

(2014) Parvaneh Pakravan et al.   Pharmacological Reports

Synthesis of 4′-[3-methyl-5-thioxo-1H-1,2,4-triazol-4(5H)-yl]-2′,5′-diphenyl-2′,4′-dihydro spiro[indolin-3,3′[1,2,4]triazol]-2-one derivatives

(2014) Atiye Bazian et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Preparation, photochromism, and complex formation with metal ions of pyrazolylazomethine derivative of spirooxazine

(2014) L. D. Popov et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Synthesis of 1′-substituted 4′,4′-dimethyl-6′-methoxy-4′H-spiro[cyclohexane-1,3′-isoquinolines]

(2014) A. N. Perevoshchikova et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Design, Synthesis, and Optimization of Balanced Dual NK1/NK3 Receptor Antagonists

(2014) Stephen Hanessian et al.   ACS Medicinal Chemistry Letters

Highly efficient [3 + 2] reaction of 3-vinylindoles with 3-indolylmethanols by Brønsted-acid catalysis

(2014) Cheng Zhang et al.   RSC Advances

Phosphine-Catalyzed Rauhut-Currier Domino Reaction: A Facile Strategy for the Construction of Carbocyclic Spirooxindoles Skeletons

(2013) Chongchong Hu et al.   Chemistry-An Asian Journal

One-Pot, Three-Component Synthesis of Novel Spiro[3H-indole-3,2′-thiazolidine]-2,4′(1H)-diones in an Ionic Liquid as a Reusable Reaction Media

(2013) Renuka Jain et al.   HELVETICA CHIMICA ACTA

Synthesis of Monospiro-2-amino-4H-pyran Derivatives Catalyzed by Propane-1-sulfonic Acid-Modified Magnetic Hydroxyapatite Nanoparticles

(2013) Leili Jalili-Baleh et al.   HELVETICA CHIMICA ACTA

One-Pot Synthesis of Dispiro[oxindole-3,3′-pyrrolidines] by Three-Component [3+2] Cycloadditions ofin situ-Generated Azomethine Ylides with 3-Benzylidene-2,3-dihydro-1H-indol-2-ones

(2013) Firouz Matloubi Moghaddam et al.   HELVETICA CHIMICA ACTA

One-Pot, Four-Component Synthesis of Novel Spiro[indeno[2,1-b]quinoxaline-11,4′-pyran]-2′-amines

(2013) Alireza Hasaninejad et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Microwave-assisted Aqueous Multicomponent Reaction: Facile Synthesis of Polyfunctionalized Indoline-spiro Fused Pyran Derivatives

(2013) Qiong Wu et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

Distinct mechanisms for spiro-carbon formation reveal biosynthetic pathway crosstalk

(2013) Yuta Tsunematsu et al.   Nature Chemical Biology

Synthetic bacteriochlorins with integral spiro-piperidine motifs

(2013) Kanumuri Ramesh Reddy et al.   NEW JOURNAL OF CHEMISTRY

Synthesis and Antimicrobial and Antifungal Activity of Carbamate-Functionized Spiro Compounds

(2013) A. V. Velikorodov et al.   PHARMACEUTICAL CHEMISTRY JOURNAL

New synthesis of nitro-substituted 3,1-benzoxazines

(2013) O. A. Andriyanova et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Spiro heterocyclization of 4,5-diaroyl-1H-pyrrole-2,3-diones with heterocyclic enamine

(2013) P. S. Silaichev et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

An organocatalytic Michael-aldol cascade: formal [3+2] annulation to construct enantioenriched spirocyclic oxindole derivatives

(2012) Shu-Wen Duan et al.   CHEMICAL COMMUNICATIONS

Isatins As Privileged Molecules in Design and Synthesis of Spiro-Fused Cyclic Frameworks

(2012) Girija S. Singh et al.   CHEMICAL REVIEWS

Fast, solvent-free and hydrogen-bonding-mediated asymmetric Michael addition in a ball mill

(2012) Yi-Feng Wang et al.   GREEN CHEMISTRY

Diketopiperazine Alkaloids Produced by the Endophytic Fungus Aspergillus fumigatus from the Stem of Erythrophloeum fordiiOliv.

(2012) Yu-Xi Liu et al.   HELVETICA CHIMICA ACTA

Enantioselective Halocyclization Using Reagents Tailored for Chiral Anion Phase-Transfer Catalysis

(2012) Yi-Ming Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Facile Synthesis of Dispirooxindole-Fused Heterocycles via Domino 1,4-Dipolar Addition and Diels–Alder Reaction of in Situ Generated Huisgen 1,4-Dipoles

(2012) Jing Sun et al.   ORGANIC LETTERS

Phenyliodine Bis(trifluoroacetate)-Mediated Oxidative C–C Bond Formation: Synthesis of 3-Hydroxy-2-oxindoles and Spirooxindoles from Anilides

(2012) Junwei Wang et al.   ORGANIC LETTERS

Two directions in spiroheterocyclization of 1H-pyrrole-2,3-diones upon the action of 3-arylamino-1H-inden-1-ones

(2012) M. V. Dmitriev et al.   RUSSIAN CHEMICAL BULLETIN

A new ligand system based on 7′-hydroxy-3-methyl-8′-formyl-3,4-dihydro-2H-1,3-benzoxazine-2-spiro-2(H)-chromene Ferrocenoylhydrazone

(2012) E. A. Raspopova et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Synthesis of spiroindoline phytoalexin (S)-(−)-spirobrassinin and its unnatural (R)-(+)-enantiomer

(2012) Mariana Budovská et al.   TETRAHEDRON

Diastereoselective synthesis of 3,3-disubstituted oxindoles from atropisomeric N-aryl oxindole derivatives

(2012) Atsuo Nakazaki et al.   TETRAHEDRON LETTERS

Aromatic Rings in Chemical and Biological Recognition: Energetics and Structures

(2011) Laura M. Salonen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Binary-Acid Catalysis with InBr3 in the Inverse-Electron-Demanding Hetero-Diels-Alder Reaction of Mono- and Bis-Substituted Cyclopentadienes: Remote Fluoro-Effect on Stereocontrol

(2011) Jian Lv et al.   CHEMISTRY-A EUROPEAN JOURNAL

Diversity-Oriented Synthesis of Novel 2′-Aminospiro[11H-indeno[1,2-b]quinoxaline-11,4′-[4H]pyran] Derivatives via a One-Pot Four-Component Reaction

(2011) Alireza Hasaninejad et al.   HELVETICA CHIMICA ACTA

Efficient and Chemoselective Methods for the Synthesis of Some Isobenzofuran and Spiro[isobenzofuran-1,2′-pyrrole] Derivatives

(2011) Mohammad R. Mohammadizadeh et al.   HELVETICA CHIMICA ACTA

A New Four-Component Reaction for the Synthesis of Spiro[4H-indeno[1,2-b]pyridine-4,3′-[3H]indoles]

(2011) Afsaneh Feiz et al.   HELVETICA CHIMICA ACTA

Organic Reaction in Water: A Highly Efficient and Environmentally Friendly Synthesis of Spiro Compounds Catalyzed by L-Proline

(2011) Minoo Dabiri et al.   HELVETICA CHIMICA ACTA

A Novel, One-Pot Four-Component Route to 2′-Thioxo-2′,3′-dihydrospiro[indole-3,6′-[1,3]thiazin]-2-one Derivatives

(2011) Abdolali Alizadeh et al.   HELVETICA CHIMICA ACTA

An efficient synthesis of fluorescent spiro[benzopyrazoloquinoline-indoline]triones and spiro[acenaphthylenebenzopyrazoloquinoline]triones

(2011) Minoo Dabiri et al.   MONATSHEFTE FUR CHEMIE

Diastereoselective synthesis of spiro derivatives of 3-substituted 2,3,4,4a,5,6-hexahydro-1H-benzo[c]quinolizines

(2011) T. V. Glukhareva et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of new spiro compounds containing a carbamate group

(2011) A. V. Velikorodov et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 3-pyrrol-3′-yloxindoles with a carbamate function

(2011) A. V. Velikorodov et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

L-proline-catalyzed 1,3-dipolar cycloaddition of some Schiff bases to methyl 4-[1-oxo-2-(2-oxo-2,3-dihydro-1H-indol-3-ylidene)ethyl]phenylcarbamate

(2011) A. V. Velikorodov et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Three-component synthesis of spiro compounds with a carbamate functionality

(2011) A. V. Velikorodov et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis of the Polycyclic Fungal Metabolite (±)-Communesin F

(2010) Peng Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Organocatalytic [3+2] Cyclisation Strategy for the Highly Enantioselective Synthesis of Spirooxindoles

(2010) Arnaud Voituriez et al.   CHEMISTRY-A EUROPEAN JOURNAL

Two Novel Sesquiterpenoids from the Roots of Ferula ferulaeoides (Steud.) Korov.

(2010) Yue Hu et al.   HELVETICA CHIMICA ACTA

Efficient and Convenient Polyethylene Glycol (PEG)-Mediated Synthesis of Spiro-oxindoles

(2010) Harshadas Mitaram Meshram et al.   HELVETICA CHIMICA ACTA

Discovery of (7R)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase

(2010) Frank Narjes et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pd-Catalyzed Assembly of Spirooxindole Natural Products: A Short Synthesis of Horsfiline

(2010) Nina Deppermann et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of a Highly Luminescent Three-Dimensional Pyrene Dye Based on the Spirobifluorene Skeleton

(2010) Kentaro Sumi et al.   MOLECULES

First C−H Activation Route to Oxindoles using Copper Catalysis

(2010) Johannes E. M. N. Klein et al.   ORGANIC LETTERS

Palladium-Catalyzed Carbo-Heterofunctionalization of Alkenes for the Synthesis of Oxindoles and Spirooxindoles

(2010) Stéphanie Jaegli et al.   ORGANIC LETTERS

Investigation of complexation of functionalized 1,3-benzoxazinone spiropyrans with metal ions

(2010) V. A. Barachevskii et al.   RUSSIAN JOURNAL OF GENERAL CHEMISTRY

Synthesis of 4′H-spiro[adamantane-2,3′-isoquinoline] derivatives

(2010) Yu. S. Rozhkova et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Three-component synthesis of 1-substituted 6′,7′-dimethoxy-4′H-spiro[adamantane-2,3′-isoquinolines]

(2010) Yu. S. Rozhkova et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Five-membered 2,3-dioxo heterocycles: LXX. Spiro heterocyclization of 1H-pyrrole-2,3-diones by the action of 1,5-binucleophiles. Crystalline and molecular structure of ethyl 1′-benzyl-7-methoxy-3,3-dimethyl-1,2′-dioxo-5′-phenyl-1′,2,2′,3,4,10-hexahydro-1H-spiro[acridine-9,3′-pyrrole]-4′-carboxylate

(2010) P. S. Silaichev et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Some condensations of methyl 4-acetylphenylcarbamate

(2010) A. V. Velikorodov et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Synthetic aspects of the oxidative amidation of phenols

(2010) Huan Liang et al.   TETRAHEDRON

Generation ofN-(tert-Butoxycarbonyl)indole-2,3-quinodimethane and Its [4+2]-Type Cycloaddition

(2009) Fuyuhiko Inagaki et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Highly Diastereoselective Oxidative Cascade Cyclization Reactions

(2009) Kai-Tai Yip et al.   ORGANIC LETTERS

Synthesis of fused 2′-amino-3′-R-spiro-[indole-3,4′-pyran]-2(1H)-ones

(2009) L. A. Shemchuk et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

An Expedient Strategy for the Synthesis of Tryptamines and Other Heterocycles

(2008) K. C. Nicolaou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Spiro Skeletons: A Class of Privileged Structure for Chiral Ligand Design

(2008) Kuiling Ding et al.   Chemistry-An Asian Journal

Mn(III)-based radical addition reactions of 2-nitroindole with activated CH compounds

(2008) Dmitry A. Androsov et al.   TETRAHEDRON LETTERS