IL‐17A expressed on neutrophil extracellular traps promotes mesenchymal stem cell differentiation toward bone‐forming cells in ankylosing spondylitis

GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis

(2020) Daniel Regan-Komito et al.   Nature Communications

The Effect of Therapy on Radiographic Progression in Axial Spondyloarthritis: A Systematic Review and Meta‐Analysis

(2020) Paras Karmacharya et al.   Arthritis & Rheumatology

Bone formation in axial spondyloarthritis: Is disease modification possible?

(2020) Akihiro Nakamura et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Neutrophil extracellular traps mediate articular cartilage damage and enhance cartilage component immunogenicity in rheumatoid arthritis

(2020) Carmelo Carmona-Rivera et al.   JCI Insight

Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

(2020) Panagiotis Skendros et al.   JOURNAL OF CLINICAL INVESTIGATION

To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps

(2019) Sebastian Boeltz et al.   CELL DEATH AND DIFFERENTIATION

Life and death of circulating cell-free DNA

(2019) Anatoli Kustanovich et al.   CANCER BIOLOGY & THERAPY

Neutrophil extracellular traps may contribute to the pathogenesis in adult-onset Still’s disease

(2019) Mi-Hyun Ahn et al.   JOURNAL OF RHEUMATOLOGY

The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies

(2019) Dennis G McGonagle et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophil Diversity in Health and Disease

(2019) Carlos Silvestre-Roig et al.   TRENDS IN IMMUNOLOGY

The IL-1 family of cytokines and receptors in rheumatic diseases

(2019) Charles Anthony Dinarello   Nature Reviews Rheumatology

IL‐17 alters the mesenchymal stem cell niche towards osteogenesis in cooperation with osteocytes

(2019) Chongshan Liao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Deadliest catch

(2019) Rishi R. Goel et al.   CURRENT OPINION IN RHEUMATOLOGY

Nature versus nurture in the spectrum of rheumatic diseases: Classification of spondyloarthritis as autoimmune or autoinflammatory

(2018) Elena Generali et al.   AUTOIMMUNITY REVIEWS

REDD1/Autophagy Pathway Is Associated with Neutrophil-Driven IL-1β Inflammatory Response in Active Ulcerative Colitis

(2018) Iliana Angelidou et al.   JOURNAL OF IMMUNOLOGY

Interleukin-17A promotes osteogenic differentiation by increasing OPG/RANKL ratio in stem cells from human exfoliated deciduous teeth (SHED)

(2018) Alphy-Alphonsa Sebastian et al.   Journal of Tissue Engineering and Regenerative Medicine

IL17/IL17RA as a Novel Signaling Axis Driving Mesenchymal Stem Cell Therapeutic Function in Experimental Autoimmune Encephalomyelitis

(2018) Mónica Kurte et al.   Frontiers in Immunology

Effects of the IL-23–IL-17 pathway on bone in spondyloarthritis

(2018) Ellen M. Gravallese et al.   Nature Reviews Rheumatology

Clarithromycin Enhances the Antibacterial Activity and Wound Healing Capacity in Type 2 Diabetes Mellitus by Increasing LL-37 Load on Neutrophil Extracellular Traps

(2018) Athanasios Arampatzioglou et al.   Frontiers in Immunology

REDD1/autophagy pathway promotes thromboinflammation and fibrosis in human systemic lupus erythematosus (SLE) through NETs decorated with tissue factor (TF) and interleukin-17A (IL-17A)

(2018) Eleni Frangou et al.   ANNALS OF THE RHEUMATIC DISEASES

IL-17A Inhibition Diminishes Inflammation and New Bone Formation In Experimental Spondyloarthritis

(2018) Melissa N. van Tok et al.   Arthritis & Rheumatology

Regulated in development and DNA damage responses 1 (REDD1) links stress with IL-1β–mediated familial Mediterranean fever attack through autophagy-driven neutrophil extracellular traps

(2017) Panagiotis Skendros et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An emerging role for neutrophil extracellular traps in noninfectious disease

(2017) Selina K Jorch et al.   NATURE MEDICINE

Enthesitis: from pathophysiology to treatment

(2017) Georg Schett et al.   Nature Reviews Rheumatology

In vitro induction of NETosis: Comprehensive live imaging comparison and systematic review

(2017) Tamara Hoppenbrouwers et al.   PLoS One

What is the best treatment target in axial spondyloarthritis: tumour necrosis factor α, interleukin 17, or both?

(2017) Denis Poddubnyy et al.   RHEUMATOLOGY

Interleukin-17A-promoted MSC2 polarization related with new bone formation of ankylosing spondylitis

(2017) Tao He et al.   Oncotarget

Differential expression of cell cycle and WNT pathway-related genes accounts for differences in the growth and differentiation potential of Wharton’s jelly and bone marrow-derived mesenchymal stem cells

(2017) Aristea K. Batsali et al.   Stem Cell Research & Therapy

Mechanism of New Bone Formation in Axial Spondyloarthritis

(2017) Denis Poddubnyy et al.   Current Rheumatology Reports

NETopathies? Unraveling the Dark Side of Old Diseases through Neutrophils

(2017) Alexandros Mitsios et al.   Frontiers in Immunology

Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?

(2016) Q Chen et al.   CELL DEATH AND DIFFERENTIATION

Ankylosing Spondylitis and Axial Spondyloarthritis

(2016) Joel D. Taurog et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-17-producing γδ T cells enhance bone regeneration

(2016) Takehito Ono et al.   Nature Communications

Immunomodulatory Role of Clarithromycin in Acinetobacter baumannii Infection via Formation of Neutrophil Extracellular Traps

(2015) Theocharis Konstantinidis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction

(2015) Dimitrios A. Stakos et al.   EUROPEAN HEART JOURNAL

The 3 major types of innate and adaptive cell-mediated effector immunity

(2015) Francesco Annunziato et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

The Association Between Neutrophil/Lymphocyte Ratio and Disease Activity in Rheumatoid Arthritis and Ankylosing Spondylitis

(2015) Ridvan Mercan et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Release of Neutrophil Extracellular Traps by Neutrophils Stimulated With Antiphospholipid Antibodies: A Newly Identified Mechanism of Thrombosis in the Antiphospholipid Syndrome

(2015) Srilakshmi Yalavarthi et al.   Arthritis & Rheumatology

Neutrophil extracellular traps regulate IL-1β-mediated inflammation in familial Mediterranean fever

(2014) Eirini Apostolidou et al.   ANNALS OF THE RHEUMATIC DISEASES

Neutrophil extracellular traps promote differentiation and function of fibroblasts

(2014) Akrivi Chrysanthopoulou et al.   JOURNAL OF PATHOLOGY

Health-related quality of life in patients with ankylosing spondylitis: a comprehensive review

(2014) Konstantinos Kotsis et al.   Expert Review of Pharmacoeconomics & Outcomes Research

Effects of Interleukin-17A on Osteogenic Differentiation of Isolated Human Mesenchymal Stem Cells

(2014) Bilal Osta et al.   Frontiers in Immunology

Complex diseases require complex therapies

(2013) Ravi Iyengar   EMBO REPORTS

In Vivo Induction of Cutaneous Inflammation Results in the Accumulation of Extracellular Trap-Forming Neutrophils Expressing RORγt and IL-17

(2013) Romy R.M.C Keijsers et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2

(2013) Patricia R Taylor et al.   NATURE IMMUNOLOGY

Interleukin-1β induces differentiation of human mesenchymal stem cells into osteoblasts via the Wnt-5a/receptor tyrosine kinase-like orphan receptor 2 pathway

(2012) Koshiro Sonomoto et al.   ARTHRITIS AND RHEUMATISM

Levels of Circulating Th17 Cells and Regulatory T Cells in Ankylosing Spondylitis Patients with an Inadequate Response to Anti−TNF-α Therapy

(2012) Li Xueyi et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury

(2012) Axelle Caudrillier et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4−CD8− entheseal resident T cells

(2012) Jonathan P Sherlock et al.   NATURE MEDICINE

Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones

(2012) Mona Saffarzadeh et al.   PLoS One

T-Lymphocytes Enable Osteoblast Maturation via IL-17F during the Early Phase of Fracture Repair

(2012) Diane Nam et al.   PLoS One

Mast Cells and Neutrophils Release IL-17 through Extracellular Trap Formation in Psoriasis

(2011) A. M. Lin et al.   JOURNAL OF IMMUNOLOGY

Analysis of IL-17+ cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response

(2011) Heiner Appel et al.   ARTHRITIS RESEARCH & THERAPY

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Functional, molecular and proteomic characterisation of bone marrow mesenchymal stem cells in rheumatoid arthritis

(2007) M-C Kastrinaki et al.   ANNALS OF THE RHEUMATIC DISEASES