Mechanism of action of Imeglimin: A novel therapeutic agent for type 2 diabetes
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mechanism of action of Imeglimin: A novel therapeutic agent for type 2 diabetes
Authors
Keywords
-
Journal
DIABETES OBESITY & METABOLISM
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2020-12-03
DOI
10.1111/dom.14277
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Molecular Mechanisms by Which Imeglimin Improves Glucose Homeostasis
- (2020) Habib Yaribeygi et al. Journal of Diabetes Research
- Absence of QTc prolongation in a thorough QT study with imeglimin, a first in class oral agent for type 2 diabetes mellitus
- (2020) Julie Dubourg et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- In vitro investigation, pharmacokinetics and disposition of imeglimin, a novel oral antidiabetic drug, in preclinical species and humans
- (2020) Clémence Chevalier et al. DRUG METABOLISM AND DISPOSITION
- Mitochondrial Dysfunction in Type 2 Diabetes Mellitus: An Organ-Based Analysis
- (2019) Mark V Pinti et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Role of Mitochondria in the Mechanism(s) of Action of Metformin
- (2019) Guillaume Vial et al. Frontiers in Endocrinology
- Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells
- (2019) Elizabeth Haythorne et al. Nature Communications
- 2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
- (2019) John B. Buse et al. DIABETOLOGIA
- Incretin hormones: Their role in health and disease
- (2018) Michael A. Nauck et al. DIABETES OBESITY & METABOLISM
- Mechanisms of Insulin Action and Insulin Resistance
- (2018) Max C. Petersen et al. PHYSIOLOGICAL REVIEWS
- De novo NAD+ synthesis enhances mitochondrial function and improves health
- (2018) Elena Katsyuba et al. NATURE
- Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents
- (2016) Rachel J. Perry et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Metformin-associated lactic acidosis: Current perspectives on causes and risk
- (2016) Ralph DeFronzo et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- New glycemic targets for patients with diabetes from the Japan Diabetes Society
- (2016) Eiichi Araki et al. Journal of Diabetes Investigation
- NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus
- (2015) Carles Cantó et al. Cell Metabolism
- Imeglimin increases glucose-dependent insulin secretion and improves β-cell function in patients with type 2 diabetes
- (2015) G. Pacini et al. DIABETES OBESITY & METABOLISM
- Apoptosis induced by NAD depletion is inhibited by KN-93 in a CaMKII-independent manner
- (2015) Mikio Takeuchi et al. EXPERIMENTAL CELL RESEARCH
- Imeglimin Normalizes Glucose Tolerance and Insulin Sensitivity and Improves Mitochondrial Function in Liver of a High-Fat, High-Sucrose Diet Mice Model
- (2015) Guillaume Vial et al. DIABETES
- Metabolic Inflexibility: When Mitochondrial Indecision Leads to Metabolic Gridlock
- (2014) Deborah M. Muoio CELL
- The Efficacy and Safety of Imeglimin as Add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Sitagliptin Monotherapy
- (2014) Pascale Fouqueray et al. DIABETES CARE
- Pharmacology, Physiology, and Mechanisms of Action of Dipeptidyl Peptidase-4 Inhibitors
- (2014) Erin E. Mulvihill et al. ENDOCRINE REVIEWS
- Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
- (2014) Anila K. Madiraju et al. NATURE
- Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future
- (2013) Steven E Kahn et al. LANCET
- Efficacy and Safety Profile Evaluation of Acarbose Alone and in Association With Other Antidiabetic Drugs: A Systematic Review
- (2012) Giuseppe Derosa et al. CLINICAL THERAPEUTICS
- The Efficacy and Safety of Imeglimin as Add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Metformin Monotherapy
- (2012) P. Fouqueray et al. DIABETES CARE
- Imeglimin, a novel glimin oral antidiabetic, exhibits a good efficacy and safety profile in type 2 diabetic patients
- (2012) V. Pirags et al. DIABETES OBESITY & METABOLISM
- Mitochondrial Dysfunction andβ-Cell Failure in Type 2 Diabetes Mellitus
- (2011) Zhongmin Alex Ma et al. Experimental Diabetes Research
- Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis
- (2011) M. Pittelli et al. MOLECULAR PHARMACOLOGY
- Protection of pancreatic INS-1 β-cells from glucose- and fructose-induced cell death by inhibiting mitochondrial permeability transition with cyclosporin A or metformin
- (2011) S Lablanche et al. Cell Death & Disease
- Acute and long-term effects of metformin on the function and insulin secretory responsiveness of clonal β-cells
- (2010) Joan M. McKiney et al. BIOLOGICAL CHEMISTRY
- Genetics of type 2 diabetes: pathophysiologic and clinical relevance
- (2010) Christian Herder et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Acute Metformin Overdose: Examining Serum pH, Lactate Level, and Metformin Concentrations in Survivors Versus Nonsurvivors: A Systematic Review of the Literature
- (2009) Damon M. Dell'Aglio et al. ANNALS OF EMERGENCY MEDICINE
- Sodium-glucose co-transporter-2 inhibitors: an emerging new class of oral antidiabetic drug
- (2009) Iskandar Idris et al. DIABETES OBESITY & METABOLISM
- The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality
- (2009) S. E. Kahn et al. DIABETOLOGIA
- Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
- (2009) Ethan J. Anderson et al. JOURNAL OF CLINICAL INVESTIGATION
- Metabolic cycling in control of glucose-stimulated insulin secretion
- (2008) Mette V. Jensen et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Role of Mitochondrial Dysfunction in Insulin Resistance
- (2008) Jeong-a Kim et al. CIRCULATION RESEARCH
- Pancreatic β-cell mass in European subjects with type 2 diabetes
- (2008) J. Rahier et al. DIABETES OBESITY & METABOLISM
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started