Incretin hormones: Their role in health and disease

Glucose-Dependent Insulinotropic Polypeptide Receptor Deficiency Leads to Impaired Bone Marrow Hematopoiesis

(2017) Fernanda Dana Mantelmacher et al.   JOURNAL OF IMMUNOLOGY

Liraglutide and Renal Outcomes in Type 2 Diabetes

(2017) Johannes F.E. Mann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of endogenous GLP-1 and GIP on glucose tolerance after Roux-en-Y gastric bypass surgery

(2016) Maria S. Svane et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucose-dependent insulinotropic polypeptide (GIP) dose-dependently reduces osteoclast differentiation and resorption

(2016) Guillaume Mabilleau et al.   BONE

The Cardiovascular Biology of Glucagon-like Peptide-1

(2016) Daniel J. Drucker   Cell Metabolism

Incretin therapies: highlighting common features and differences in the modes of action of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors

(2016) M. Nauck   DIABETES OBESITY & METABOLISM

GLP-1 receptor agonist promotes brown remodelling in mouse white adipose tissue through SIRT1

(2016) Fen Xu et al.   DIABETOLOGIA

Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery

(2016) M S Svane et al.   INTERNATIONAL JOURNAL OF OBESITY

The blunted effect of glucose-dependent insulinotropic polypeptide in subcutaneous abdominal adipose tissue in obese subjects is partly reversed by weight loss

(2016) M Asmar et al.   Nutrition & Diabetes

The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions

(2016) Michael A Nauck et al.   Lancet Diabetes & Endocrinology

Increased GIP signaling induces adipose inflammation via a HIF-1α-dependent pathway and impairs insulin sensitivity in mice

(2015) Shu Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucose-dependent insulinotropic polypeptide directly induces glucose transport in rat skeletal muscle

(2015) Laelie A. Snook et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Glucose-dependent insulinotropic polypeptide (GIP) directly affects collagen fibril diameter and collagen cross-linking in osteoblast cultures

(2015) Aleksandra Mieczkowska et al.   BONE

Chronic administration of Glucagon-like peptide-1 receptor agonists improves trabecular bone mass and architecture in ovariectomised mice

(2015) M. Pereira et al.   BONE

Bone Fracture Risk is Not Associated with the Use of Glucagon-Like Peptide-1 Receptor Agonists: A Population-Based Cohort Analysis

(2015) Johanna H. M. Driessen et al.   CALCIFIED TISSUE INTERNATIONAL

Evidence of Extrapancreatic Glucagon Secretion in Man

(2015) Asger Lund et al.   DIABETES

GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study

(2015) Kristine Færch et al.   DIABETES

Contribution of brown adipose tissue activity to the control of energy balance by GLP-1 receptor signalling in mice

(2015) Kristy M. Heppner et al.   DIABETOLOGIA

GLP-1 Receptor Agonist Treatment Increases Bone Formation and Prevents Bone Loss in Weight-Reduced Obese Women

(2015) Eva W. Iepsen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

TCF1 links GIPR signaling to the control of beta cell function and survival

(2015) Jonathan E Campbell et al.   NATURE MEDICINE

Glucagon-like peptide-1 receptor agonist Liraglutide has anabolic bone effects in ovariectomized rats without diabetes.

(2015) Nan Lu et al.   PLoS One

Glucose-Dependent Insulinotropic Polypeptide Augments Glucagon Responses to Hypoglycemia in Type 1 Diabetes

(2014) Mikkel Christensen et al.   DIABETES

Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors

(2014) K. Aaboe et al.   DIABETES OBESITY & METABOLISM

Glucose-Dependent Insulinotropic Polypeptide Inhibits Bone Resorption in Humans

(2014) Anne Nissen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A Functional Amino Acid Substitution in the Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR) Gene Is Associated With Lower Bone Mineral Density and Increased Fracture Risk

(2014) S. S. Torekov et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss

(2014) Anna Secher et al.   JOURNAL OF CLINICAL INVESTIGATION

Long-Acting Glucose-Dependent Insulinotropic Polypeptide Ameliorates Obesity-Induced Adipose Tissue Inflammation

(2014) Chen Varol et al.   JOURNAL OF IMMUNOLOGY

A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

(2014) Brian Finan et al.   NATURE MEDICINE

Glucose-dependent insulinotropic polypeptide (GIP) receptor deletion leads to reduced bone strength and quality

(2013) Aleksandra Mieczkowska et al.   BONE

GLP-1 Responses Are Heritable and Blunted in Acquired Obesity With High Liver Fat and Insulin Resistance

(2013) Niina Matikainen et al.   DIABETES CARE

Secretion of Glucose-Dependent Insulinotropic Polypeptide in Patients With Type 2 Diabetes: Systematic review and meta-analysis of clinical studies

(2013) S. Calanna et al.   DIABETES CARE

Secretion of glucagon-like peptide-1 in patients with type 2 diabetes mellitus: systematic review and meta-analyses of clinical studies

(2013) S. Calanna et al.   DIABETOLOGIA

Glucose-dependent insulinotropic polypeptide has impaired effect on abdominal, subcutaneous adipose tissue metabolism in obese subjects

(2013) M Asmar et al.   INTERNATIONAL JOURNAL OF OBESITY

Use of glucagon-like peptide-1 receptor agonists and bone fractures: A meta-analysis of randomized clinical trials (胰高血糖素样肽-1受体激动剂的使用与骨折的关系：一项对随机临床试验的meta分析)

(2013) Guillaume Mabilleau et al.   Journal of Diabetes

Effects of Roux-en-Y gastric bypass on energy and glucose homeostasis are preserved in two mouse models of functional glucagon-like peptide-1 deficiency

(2013) Mohamad Mokadem et al.   Molecular Metabolism

Glucose-dependent insulinotropic polypeptide receptor deficiency leads to modifications of trabecular bone volume and quality in mice

(2012) Christine Gaudin-Audrain et al.   BONE

Direct Control of Brown Adipose Tissue Thermogenesis by Central Nervous System Glucagon-Like Peptide-1 Receptor Signaling

(2012) S. H. Lockie et al.   DIABETES

Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes

(2012) Y.-S. Lee et al.   DIABETOLOGIA

Direct effect of GLP-1 infusion on endogenous glucose production in humans

(2012) M. Seghieri et al.   DIABETOLOGIA

A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets

(2012) P. Marchetti et al.   DIABETOLOGIA

Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits cell apoptosis induced by lipotoxicity in pancreatic β-cell line

(2012) Qian Wei et al.   PEPTIDES

GIP Does Not Potentiate the Antidiabetic Effects of GLP-1 in Hyperglycemic Patients With Type 2 Diabetes

(2011) N. Mentis et al.   DIABETES

Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction

(2011) Jacob Lønborg et al.   EUROPEAN HEART JOURNAL

Impaired Regulation of the Incretin Effect in Patients with Type 2 Diabetes

(2011) Jonatan I. Bagger et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The effect of gastric inhibitory polypeptide on intestinal glucose absorption and intestinal motility in mice

(2010) Eiichi Ogawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Is the Diminished Incretin Effect in Type 2 Diabetes Just an Epi-Phenomenon of Impaired  -Cell Function?

(2010) J. J. Meier et al.   DIABETES

Effect of gastric bypass surgery on the incretins

(2010) B. Laferrère   DIABETES & METABOLISM

Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?

(2010) M. A. Nauck et al.   DIABETOLOGIA

Molecular mechanisms underlying nutrient-stimulated incretin secretion

(2010) Helen E. Parker et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Endogenous GLP-1 Regulates Postprandial Glycemia in Humans: Relative Contributions of Insulin, Glucagon, and Gastric Emptying

(2010) Mathias Nicolaus et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

GIP increases human adipocyte LPL expression through CREB and TORC2-mediatedtrans-activation of theLPLgene

(2010) Su-Jin Kim et al.   JOURNAL OF LIPID RESEARCH

Gastric inhibitory polypeptide receptor: association analyses for obesity of several polymorphisms in large study groups

(2009) Carla IG Vogel et al.   BMC Medical Genetics

Age-Dependent Decline in  -Cell Proliferation Restricts the Capacity of  -Cell Regeneration in Mice

(2009) S.-I. Tschen et al.   DIABETES

From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

(2009) R. A. DeFronzo   DIABETES

The glucagon-like peptide 1 receptor is essential for postprandial lipoprotein synthesis and secretion in hamsters and mice

(2009) J. Hsieh et al.   DIABETOLOGIA

Endogenous Glucagon-Like Peptide-1 Slows Gastric Emptying in Healthy Subjects, Attenuating Postprandial Glycemia

(2009) Adam M. Deane et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

(2008) P. V. Højberg et al.   DIABETOLOGIA

Glucose-dependent Insulinotropic Polypeptide (GIP) Stimulates Transepithelial Glucose Transport

(2008) Satish K. Singh et al.   Obesity

Laparoscopic Duodenal–Jejunal Exclusion in the Treatment of Type 2 Diabetes Mellitus in Patients with BMI < 30 kg/m2 (LBMI)

(2008) Almino C. Ramos et al.   OBESITY SURGERY

The Murine Glucagon-Like Peptide-1 Receptor Is Essential for Control of Bone Resorption

(2007) Chizumi Yamada et al.   ENDOCRINOLOGY