What determines organ size during development and regeneration?

Regulation of Anisotropic Tissue Growth by Two Orthogonal Signaling Centers

(2020) Lara Barrio et al.   DEVELOPMENTAL CELL

mTOR at the nexus of nutrition, growth, ageing and disease

(2020) Grace Y. Liu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An intestinal zinc sensor regulates food intake and developmental growth

(2020) Siamak Redhai et al.   NATURE

Body size-dependent energy storage causes Kleiber’s law scaling of the metabolic rate in planarians

(2019) Albert Thommen et al.   eLife

Inter-Organ Growth Coordination Is Mediated by the Xrp1-Dilp8 Axis in Drosophila

(2019) Laura Boulan et al.   DEVELOPMENTAL CELL

Japan approves first human-animal embryo experiments

(2019) David Cyranoski   NATURE

Making and breaking symmetry in development, growth and disease

(2019) Daniel T. Grimes   DEVELOPMENT

Eiger/TNFα-mediated Dilp8 and ROS production coordinate intra-organ growth in Drosophila

(2019) Juan A. Sanchez et al.   PLoS Genetics

Size control of the inner ear via hydraulic feedback

(2019) Kishore R Mosaliganti et al.   eLife

The Hippo pathway integrates PI3K–Akt signals with mechanical and polarity cues to control tissue growth

(2019) Nerea Borreguero-Muñoz et al.   PLOS BIOLOGY

Signalling from the periphery to the brain that regulates energy homeostasis

(2018) Ki-Suk Kim et al.   NATURE REVIEWS NEUROSCIENCE

Peripheral and Central Nutrient Sensing Underlying Appetite Regulation

(2018) Vineet Augustine et al.   TRENDS IN NEUROSCIENCES

Cell-nonautonomous local and systemic responses to cell arrest enable long-bone catch-up growth in developing mice

(2018) Alberto Roselló-Díez et al.   PLOS BIOLOGY

Cyclin G and the Polycomb Repressive Complexes PRC1 and PR-DUB cooperate for developmental stability.

(2018) Delphine Dardalhon-Cuménal et al.   PLoS Genetics

Cross-limb communication duringXenopushind-limb regenerative response: non-local bioelectric injury signals

(2018) Sera M. Busse et al.   DEVELOPMENT

Amino acid transporters revisited: New views in health and disease

(2018) Palanivel Kandasamy et al.   TRENDS IN BIOCHEMICAL SCIENCES

An EGF-Responsive Neural Circuit Couples Insulin Secretion with Nutrition in Drosophila

(2018) Eleonora Meschi et al.   DEVELOPMENTAL CELL

Interspecies organogenesis generates autologous functional islets

(2017) Tomoyuki Yamaguchi et al.   NATURE

Growth and size control during development

(2017) Jannik Vollmer et al.   Open Biology

Dpp controls growth and patterning in Drosophila wing precursors through distinct modes of action

(2017) Pablo Sanchez Bosch et al.   eLife

Boundary Dpp promotes growth of medial and lateral regions of the Drosophila wing

(2017) Lara Barrio et al.   eLife

Interorgan Communication Pathways in Physiology: Focus onDrosophila

(2016) Ilia A. Droujinine et al.   Annual Review of Genetics

The Drosophila TNF Eiger Is an Adipokine that Acts on Insulin-Producing Cells to Mediate Nutrient Response

(2016) Neha Agrawal et al.   Cell Metabolism

Intra-organ growth coordination in Drosophila is mediated by systemic ecdysone signaling

(2016) Rewatee H. Gokhale et al.   DEVELOPMENTAL BIOLOGY

Chronic Protein Restriction in Mice Impacts Placental Function and Maternal Body Weight before Fetal Growth

(2016) Paula N. Gonzalez et al.   PLoS One

Differential growth triggers mechanical feedback that elevates Hippo signaling

(2016) Yuanwang Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila insulin release is triggered by adipose Stunted ligand to brain Methuselah receptor

(2016) R. Delanoue et al.   SCIENCE

The Hippo signalling pathway coordinates organ growth and limits developmental variability by controlling dilp8 expression

(2016) Emilie Boone et al.   Nature Communications

Growth-Blocking Peptides As Nutrition-Sensitive Signals for Insulin Secretion and Body Size Regulation

(2016) Takashi Koyama et al.   PLOS BIOLOGY

Fluctuating Asymmetry of Human Populations: A Review

(2016) John Graham et al.   Symmetry-Basel

Suppression of Insulin Production and Secretion by a Decretin Hormone

(2015) Ronald W. Alfa et al.   Cell Metabolism

Drosophila Lgr3 Couples Organ Growth with Maturation and Ensures Developmental Stability

(2015) Julien Colombani et al.   CURRENT BIOLOGY

Morphogen rules: design principles of gradient-mediated embryo patterning

(2015) J. Briscoe et al.   DEVELOPMENT

Regulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up

(2015) Alberto Roselló-Díez et al.   ENDOCRINE REVIEWS

Pervasive robustness in biological systems

(2015) Marie-Anne Félix et al.   NATURE REVIEWS GENETICS

Brain-Sparing in Intrauterine Growth Restriction: Considerations for the Neonatologist

(2015) Emily Cohen et al.   Neonatology

A brain circuit that synchronizes growth and maturation revealed through Dilp8 binding to Lgr3

(2015) Diana M. Vallejo et al.   SCIENCE

Developmental Pattern Formation in Phases

(2015) Anna Kicheva et al.   TRENDS IN CELL BIOLOGY

Dilp8 requires the neuronal relaxin receptor Lgr3 to couple growth to developmental timing

(2015) Andres Garelli et al.   Nature Communications

Dally Proteoglycan Mediates the Autonomous and Nonautonomous Effects on Tissue Growth Caused by Activation of the PI3K and TOR Pathways

(2015) Ana Ferreira et al.   PLOS BIOLOGY

The Nutrient-Responsive Hormone CCHamide-2 Controls Growth by Regulating Insulin-like Peptides in the Brain of Drosophila melanogaster

(2015) Hiroko Sano et al.   PLoS Genetics

Cytoskeletal Tension Inhibits Hippo Signaling through an Ajuba-Warts Complex

(2014) Cordelia Rauskolb et al.   CELL

Production of systemically circulating Hedgehog by the intestine couples nutrition to growth and development

(2014) Jonathan Rodenfels et al.   GENES & DEVELOPMENT

A global pattern of mechanical stress polarizes cell divisions and cell shape in the growing Drosophila wing disc

(2013) Loïc LeGoff et al.   DEVELOPMENT

Differential proliferation rates generate patterns of mechanical tension that orient tissue growth

(2013) Yanlan Mao et al.   EMBO JOURNAL

Brk regulates wing disc growth in part via repression of Myc expression

(2013) Nikolaos Doumpas et al.   EMBO REPORTS

Asymmetric flies

(2013) Vincent Debat et al.   FLY

Drosophila Cytokine Unpaired 2 Regulates Physiological Homeostasis by Remotely Controlling Insulin Secretion

(2012) Akhila Rajan et al.   CELL

Intramyocellular Fatty-Acid Metabolism Plays a Critical Role in Mediating Responses to Dietary Restriction in Drosophila melanogaster

(2012) Subhash D. Katewa et al.   Cell Metabolism

Integrating force-sensing and signaling pathways in a model for the regulation of wing imaginal disc size

(2012) T. Aegerter-Wilmsen et al.   DEVELOPMENT

Imaginal Discs Secrete Insulin-Like Peptide 8 to Mediate Plasticity of Growth and Maturation

(2012) A. Garelli et al.   SCIENCE

Comment on "Dynamics of Dpp Signaling and Proliferation Control"

(2012) G. Schwank et al.   SCIENCE

Secreted Peptide Dilp8 Coordinates Drosophila Tissue Growth with Developmental Timing

(2012) J. Colombani et al.   SCIENCE

Anaplastic Lymphoma Kinase Spares Organ Growth during Nutrient Restriction in Drosophila

(2011) Louise Y. Cheng et al.   CELL

The coordination of growth among Drosophila organs in response to localized growth-perturbation

(2011) Nathan F. Parker et al.   DEVELOPMENTAL BIOLOGY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Dynamics of Dpp Signaling and Proliferation Control

(2011) O. Wartlick et al.   SCIENCE

Developmental Stability: A Major Role for Cyclin G in Drosophila melanogaster

(2011) Vincent Debat et al.   PLoS Genetics

FOXO Regulates Organ-Specific Phenotypic Plasticity In Drosophila

(2011) Hui Yuan Tang et al.   PLoS Genetics

A dp53-Dependent Mechanism Involved in Coordinating Tissue Growth in Drosophila

(2010) Duarte Mesquita et al.   PLOS BIOLOGY

Mechanisms of Growth and Homeostasis in the Drosophila Wing

(2009) Ricardo M. Neto-Silva et al.   Annual Review of Cell and Developmental Biology

Determination of mechanical stress distribution in Drosophila wing discs using photoelasticity

(2009) Ulrike Nienhaus et al.   MECHANISMS OF DEVELOPMENT

Cell Lineages and the Logic of Proliferative Control

(2009) Arthur D Lander et al.   PLOS BIOLOGY

Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels

(2008) G. Schwank et al.   DEVELOPMENT

An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth

(2008) Jamie M. Verheyden et al.   NATURE

Achieving bilateral symmetry during vertebrate limb development

(2008) Patrick Allard et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY