Eiger/TNFα-mediated Dilp8 and ROS production coordinate intra-organ growth in Drosophila

JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress

(2019) Andrea Cosolo et al.   eLife

Yorkie and JNK Control Tumorigenesis in Drosophila Cells with Cytokinesis Failure

(2018) Stephan U. Gerlach et al.   Cell Reports

Feedback amplification loop drives malignant growth in epithelial tissues

(2017) Mariana Muzzopappa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular Reactive Oxygen Species Drive Apoptosis-Induced Proliferation via Drosophila Macrophages

(2016) Caitlin E. Fogarty et al.   CURRENT BIOLOGY

Intra-organ growth coordination in Drosophila is mediated by systemic ecdysone signaling

(2016) Rewatee H. Gokhale et al.   DEVELOPMENTAL BIOLOGY

Gene Dosage Imbalance Contributes to Chromosomal Instability-Induced Tumorigenesis

(2016) Marta Clemente-Ruiz et al.   DEVELOPMENTAL CELL

Growth Coordination During Drosophila melanogaster Imaginal Disc Regeneration Is Mediated by Signaling Through the Relaxin Receptor Lgr3 in the Prothoracic Gland

(2016) J. S. Jaszczak et al.   GENETICS

The Hippo signalling pathway coordinates organ growth and limits developmental variability by controlling dilp8 expression

(2016) Emilie Boone et al.   Nature Communications

A genome-wide resource for the analysis of protein localisation in Drosophila

(2016) Mihail Sarov et al.   eLife

Localized JNK signaling regulates organ size during development

(2016) Helen Rankin Willsey et al.   eLife

Drosophila Lgr3 Couples Organ Growth with Maturation and Ensures Developmental Stability

(2015) Julien Colombani et al.   CURRENT BIOLOGY

Nitric Oxide Synthase Regulates Growth Coordination During Drosophila melanogaster Imaginal Disc Regeneration

(2015) Jacob S. Jaszczak et al.   GENETICS

The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth

(2015) Ditte S. Andersen et al.   NATURE

p53 in survival, death and metabolic health: a lifeguard with a licence to kill

(2015) Flore Kruiswijk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DuringDrosophiladisc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay

(2015) Tomonori Katsuyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A brain circuit that synchronizes growth and maturation revealed through Dilp8 binding to Lgr3

(2015) Diana M. Vallejo et al.   SCIENCE

Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53

(2015) K. W. Yoon et al.   SCIENCE

Dilp8 requires the neuronal relaxin receptor Lgr3 to couple growth to developmental timing

(2015) Andres Garelli et al.   Nature Communications

Ecdysone promotes growth of imaginal discs through the regulation of Thor in D. melanogaster

(2015) Leire Herboso et al.   Scientific Reports

ROS-Induced JNK and p38 Signaling Is Required for Unpaired Cytokine Activation during Drosophila Regeneration

(2015) Paula Santabárbara-Ruiz et al.   PLoS Genetics

Nitric Oxide Synthase Regulates Growth Coordination During Drosophila melanogaster Imaginal Disc Regeneration

(2015) Jacob S. Jaszczak et al.   GENETICS

Supercompetitor Status of Drosophila Myc Cells Requires p53 as a Fitness Sensor to Reprogram Metabolism and Promote Viability

(2014) Claire de la Cova et al.   Cell Metabolism

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Stem cells and the impact of ROS signaling

(2014) C. L. Bigarella et al.   DEVELOPMENT

The Drosophila TNF ortholog Eiger: Emerging physiological roles and evolution of the TNF system

(2014) Tatsushi Igaki et al.   SEMINARS IN IMMUNOLOGY

The PERK pathway independently triggers apoptosis and a Rac1/Slpr/JNK/Dilp8 signaling favoring tissue homeostasis in a chronic ER stress Drosophila model

(2014) Y Demay et al.   Cell Death & Disease

MicroRNA-Mediated Regulation of Dp53 in the Drosophila Fat Body Contributes to Metabolic Adaptation to Nutrient Deprivation

(2014) Lara Barrio et al.   Cell Reports

Sustained production of ROS triggers compensatory proliferation and is required for regeneration to proceed

(2013) Carole Gauron et al.   Scientific Reports

Apoptotic cells can induce non-autonomous apoptosis through the TNF pathway

(2013) Ainhoa Pérez-Garijo et al.   eLife

Drosophila p53 isoforms differentially regulate apoptosis and apoptosis-induced proliferation

(2012) M-L Dichtel-Danjoy et al.   CELL DEATH AND DIFFERENTIATION

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

(2012) S. G. Landt et al.   GENOME RESEARCH

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Genome-Wide Expression Analysis Identifies a Modulator of Ionizing Radiation-Induced p53-Independent Apoptosis in Drosophila melanogaster

(2012) Petra van Bergeijk et al.   PLoS One

Aneuploidy-induced delaminating cells drive tumorigenesis in Drosophila epithelia

(2012) A. Dekanty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaginal Discs Secrete Insulin-Like Peptide 8 to Mediate Plasticity of Growth and Maturation

(2012) A. Garelli et al.   SCIENCE

Secreted Peptide Dilp8 Coordinates Drosophila Tissue Growth with Developmental Timing

(2012) J. Colombani et al.   SCIENCE

Elimination of Oncogenic Neighbors by JNK-Mediated Engulfment in Drosophila

(2011) Shizue Ohsawa et al.   DEVELOPMENTAL CELL

Signal transduction by reactive oxygen species

(2011) Toren Finkel   JOURNAL OF CELL BIOLOGY

p53, Oxidative Stress, and Aging

(2010) Dongping Liu et al.   ANTIOXIDANTS & REDOX SIGNALING

The Steroid Hormone Ecdysone Controls Systemic Growth by Repressing dMyc Function in Drosophila Fat Cells

(2010) Rénald Delanoue et al.   DEVELOPMENTAL CELL

A dp53-Dependent Mechanism Involved in Coordinating Tissue Growth in Drosophila

(2010) Duarte Mesquita et al.   PLOS BIOLOGY

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila

(2008) Gerasimos P. Sykiotis et al.   DEVELOPMENTAL CELL

Origin and proliferation of blastema cells during regeneration of Drosophila wing imaginal discs

(2008) Manel Bosch et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY