Intranasal insulin improves mitochondrial function and attenuates motor deficits in a rat 6‐OHDA model of Parkinson's disease

Adipose-derived stem cells modulate BV2 microglial M1/M2 polarization by producing glial cell-derived neurotrophic factor

(2020) ZHENZHONG ZHONG et al.   STEM CELLS AND DEVELOPMENT

Development of early diagnosis of Parkinson's disease: Illusion or reality?

(2020) Michael Ugrumov   CNS Neuroscience & Therapeutics

Teaching the basics of repurposing mitochondria-targeted drugs: From Parkinson's disease to cancer and back to Parkinson's disease

(2020) Balaraman Kalyanaraman   Redox Biology

Environmental neurotoxicant-induced dopaminergic neurodegeneration: a potential link to impaired neuroinflammatory mechanisms

(2019) Arthi Kanthasamy et al.   PHARMACOLOGY & THERAPEUTICS

LRP1 activation attenuates white matter injury by modulating microglial polarization through Shc1/PI3K/Akt pathway after subarachnoid hemorrhage in rats

(2019) Jianhua Peng et al.   Redox Biology

Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes

(2019) Gregory N. Ruegsegger et al.   FASEB JOURNAL

Mitochondrial integrity in neurodegeneration

(2019) Katrina Cowan et al.   CNS Neuroscience & Therapeutics

Transplantation of Nurr1-overexpressing neural stem cells and microglia for treating parkinsonian rats

(2019) Yuan Qian et al.   CNS Neuroscience & Therapeutics

Safety and preliminary efficacy of intranasal insulin for cognitive impairment in Parkinson disease and multiple system atrophy: A double-blinded placebo-controlled pilot study

(2019) Peter Novak et al.   PLoS One

An update on reactive astrocytes in chronic pain

(2019) Ting Li et al.   Journal of Neuroinflammation

Parkinson's disease: Mechanisms, translational models and management strategies

(2019) Chand Raza et al.   LIFE SCIENCES

Intranasal delivery of low-dose insulin ameliorates motor dysfunction and dopaminergic cell death in a 6-OHDA rat model of Parkinson’s Disease

(2019) Jared M. Fine et al.   NEUROSCIENCE LETTERS

Mitochondria protection as a mechanism underlying the hepatoprotective effects of glycine in cholestatic mice

(2018) Reza Heidari et al.   BIOMEDICINE & PHARMACOTHERAPY

Aging modulates microglia phenotypes in neuroinflammation of MPTP-PD mice

(2018) Kai Yao et al.   EXPERIMENTAL GERONTOLOGY

A review of brain insulin signaling in mood disorders: From biomarker to clinical target

(2018) Thanh Thanh L. Nguyen et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

MFG-E8 reverses microglial-induced neurotoxic astrocyte (A1) via NF-κB and PI3K-Akt pathways

(2018) Xiaotian Xu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The effects of insulin on the inflammatory activity of BV2 microglia

(2018) Fiona Brabazon et al.   PLoS One

Links Between Obesity-Induced Brain Insulin Resistance, Brain Mitochondrial Dysfunction, and Dementia

(2018) Jirapas Sripetchwandee et al.   Frontiers in Endocrinology

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments

(2017) Panchanan Maiti et al.   Translational Neurodegeneration

Docosahexaenoic acid up-regulates both PI3K/AKT-dependent FABP7-PPARγ interaction and MKP3 that enhance GFAP in developing rat brain astrocytes

(2016) Sachin Tripathi et al.   JOURNAL OF NEUROCHEMISTRY

MFG-E8 Selectively Inhibited Aβ-Induced Microglial M1 Polarization via NF-κB and PI3K-Akt Pathways

(2016) Xiaolei Shi et al.   MOLECULAR NEUROBIOLOGY

Transfer of mitochondria from astrocytes to neurons after stroke

(2016) Kazuhide Hayakawa et al.   NATURE

Understanding Dopaminergic Cell Death Pathways in Parkinson Disease

(2016) Patrick P. Michel et al.   NEURON

Intranasal insulin protects against substantia nigra dopaminergic neuronal loss and alleviates motor deficits induced by 6-OHDA in rats

(2016) Y. Pang et al.   NEUROSCIENCE

Insulin resistance and Parkinson’s disease: A new target for disease modification?

(2016) D. Athauda et al.   PROGRESS IN NEUROBIOLOGY

Allicin Protects PC12 Cells Against 6-OHDA-Induced Oxidative Stress and Mitochondrial Dysfunction via Regulating Mitochondrial Dynamics

(2015) Hao Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Understanding the susceptibility of dopamine neurons to mitochondrial stressors in Parkinson's disease

(2015) Dominik Haddad et al.   FEBS LETTERS

The insulin response integrates increased TGF-β signaling through Akt-induced enhancement of cell surface delivery of TGF-β receptors

(2015) Erine H. Budi et al.   Science Signaling

The insulin response integrates increased TGF-β signaling through Akt-induced enhancement of cell surface delivery of TGF-β receptors

(2015) Erine H. Budi et al.   Science Signaling

Loss of Mitochondrial Fission Depletes Axonal Mitochondria in Midbrain Dopamine Neurons

(2014) A. Berthet et al.   JOURNAL OF NEUROSCIENCE

Insulin exerts neuroprotective effects via Akt/Bcl-2 signaling pathways in differentiated SH-SY5Y cells

(2014) Mahesh Ramalingam et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: Targets for disease modification?

(2014) Fares Bassil et al.   PROGRESS IN NEUROBIOLOGY

Vesicular Glycolysis Provides On-Board Energy for Fast Axonal Transport

(2013) Diana Zala et al.   CELL

The Scaffold Protein Atg11 Recruits Fission Machinery to Drive Selective Mitochondria Degradation by Autophagy

(2013) Kai Mao et al.   DEVELOPMENTAL CELL

Role of Oxidative Stress in Parkinson's Disease

(2013) Onyou Hwang   Experimental Neurobiology

Endogenous transforming growth factor-beta promotes quiescence of primary microglia in vitro

(2012) Björn Spittau et al.   GLIA

Rosiglitazone, a PPAR-γ agonist, protects against striatal dopaminergic neurodegeneration induced by 6-OHDA lesions in the substantia nigra of rats

(2012) Eun Young Lee et al.   TOXICOLOGY LETTERS

Effect of garlic-derived organosulfur compounds on mitochondrial function and integrity in isolated mouse liver mitochondria

(2012) Andres A. Caro et al.   TOXICOLOGY LETTERS

PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington disease

(2011) Elahe Taherzadeh-Fard et al.   Molecular Neurodegeneration

Nuclear Control of Respiratory Chain Expression by Nuclear Respiratory Factors and PGC-1-Related Coactivator

(2010) Richard C. Scarpulla   Annals of the New York Academy of Sciences

Regulation of mitochondrial biogenesis

(2010) François R. Jornayvaz et al.   Essays in Biochemistry

Insulin signaling meets mitochondria in metabolism

(2010) Zhiyong Cheng et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Awake Intranasal Insulin Delivery Modifies Protein Complexes and Alters Memory, Anxiety, and Olfactory Behaviors

(2009) D. R. Marks et al.   JOURNAL OF NEUROSCIENCE

Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1

(2008) Claude A. Piantadosi et al.   CIRCULATION RESEARCH

Insulin Reduces Cerebral Ischemia/Reperfusion Injury in the Hippocampus of Diabetic Rats: A Role for Glycogen Synthase Kinase-3 

(2008) M. Collino et al.   DIABETES

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark