Cucurbitacin IIb improved active chromatin‐induced systemic lupus erythematosus via balancing the percentage of Th17 and Treg cells

Seroconversion to antinuclear antibody negativity and its association with disease flare in patients with systemic lupus erythematosus

(2020) Oh Chan Kwon et al.   LUPUS

Cucurbitacin IIb, a steroidal triterpene from Ibervillea sonorae induces antiproliferative and apoptotic effects on cervical and lung cancer cells

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T Cell Metabolism: A New Perspective on Th17/Treg Cell Imbalance in Systemic Lupus Erythematosus

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Regulatory T-cell levels in systemic lupus erythematosus patients: a meta-analysis

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Management strategies and future directions for systemic lupus erythematosus in adults

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Restoring T-helper 17 cell/regulatory T-cell balance and decreasing disease activity by rapamycin and all-trans retinoic acid in patients with systemic lupus erythematosus

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Vasoactive intestinal peptide ameliorates renal injury in a pristane-induced lupus mouse model by modulating Th17/Treg balance

(2019) Dongdong Fu et al.   BMC Nephrology

Cucurbitacin IIa interferes with EGFR-MAPK signaling pathway leads to proliferation inhibition in A549 cells

(2019) Jie Zhang et al.   FOOD AND CHEMICAL TOXICOLOGY

High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

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Emerging Targets for the Treatment of Lupus Erythematosus: There is No Royal Road to Treating Lupus

(2018) Shinsuke Yasuda   Modern Rheumatology

Soluble MHC class II-driven therapy for a systemic lupus erythematosus murine experimental in vitro and in vivo model

(2018) K. Bakela et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus

(2018) Takayuki Katsuyama et al.   Frontiers in Immunology

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(2018) Andrea Fava et al.   JOURNAL OF AUTOIMMUNITY

Allogeneic adipose-derived stem cells suppress mTORC1 pathway in a murine model of systemic lupus erythematosus

(2018) S. Wei et al.   LUPUS

CKD-506, a novel HDAC6-selective inhibitor, improves renal outcomes and survival in a mouse model of systemic lupus erythematosus

(2018) Eun Wha Choi et al.   Scientific Reports

Regulation of T Cell Activation and Differentiation by Extracellular Vesicles and Their Pathogenic Role in Systemic Lupus Erythematosus and Multiple Sclerosis

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Systemic lupus erythematosus

(2016) Arvind Kaul et al.   Nature Reviews Disease Primers

Immune Regulation of Metabolic Homeostasis in Health and Disease

(2015) Jonathan R. Brestoff et al.   CELL

The regulation of the Treg/Th17 balance by mesenchymal stem cells in human systemic lupus erythematosus

(2015) Dandan Wang et al.   Cellular & Molecular Immunology

Th1/Th2/Th17/Treg cytokine imbalance in systemic lupus erythematosus (SLE) patients: Correlation with disease activity

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Cucurbitacin IIb Exhibits Anti-Inflammatory Activity through Modulating Multiple Cellular Behaviors of Mouse Lymphocytes

(2014) Yao Wang et al.   PLoS One

Anti-proliferative effect of 23,24-dihydrocucurbitacin F on human prostate cancer cells through induction of actin aggregation and cofilin-actin rod formation

(2012) Shuai Ren et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

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(2012) Henrike Sell et al.   Nature Reviews Endocrinology

Effects of cucurbitacins on cell morphology are associated with sensitization of renal carcinoma cells to TRAIL-induced apoptosis

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Cucurbitacin: Ancient Compound Shedding New Light on Cancer Treatment

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