High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus

The majority of Swedish systemic lupus erythematosus patients are still affected by irreversible organ impairment: factors related to damage accrual in two regional cohorts

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TheSTAT4SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE

(2018) Niklas Hagberg et al.   ANNALS OF THE RHEUMATIC DISEASES

Recent developments in systemic lupus erythematosus pathogenesis and applications for therapy

(2018) Mindy S. Lo et al.   CURRENT OPINION IN RHEUMATOLOGY

A plausibly causal functional lupus-associated risk variant in the STAT1–STAT4 locus

(2018) Zubin H Patel et al.   HUMAN MOLECULAR GENETICS

Transancestral mapping and genetic load in systemic lupus erythematosus

(2017) Carl D. Langefeld et al.   Nature Communications

A comparison of genetic risk score with family history for estimating prostate cancer risk

(2016) BrianT Helfand   ASIAN JOURNAL OF ANDROLOGY

Update on Lupus Nephritis

(2016) Salem Almaani et al.   Clinical Journal of the American Society of Nephrology

Genetic risk and longitudinal disease activity in systemic lupus erythematosus using targeted maximum likelihood estimation

(2016) M A Gianfrancesco et al.   GENES AND IMMUNITY

Presence of Antiphospholipid Antibodies as a Risk Factor for Thrombotic Events in Patients with Connective Tissue Diseases and Idiopathic Thrombocytopenic Purpura

(2016) Koji Habe et al.   INTERNAL MEDICINE

The role of autophagy in the pathogenesis of systemic lupus erythematosus

(2016) Xiao Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Genome-wide association meta-analysis in Chinese and European individuals identifies ten new loci associated with systemic lupus erythematosus

(2016) David L Morris et al.   NATURE GENETICS

Clinical features and long-term outcomes of systemic lupus erythematosus: comparative data of childhood, adult and late-onset disease in a national register

(2016) S. Sousa et al.   RHEUMATOLOGY INTERNATIONAL

Risk of End-Stage Renal Disease in Patients With Lupus Nephritis, 1971-2015: A Systematic Review and Bayesian Meta-Analysis

(2016) Maria G. Tektonidou et al.   Arthritis & Rheumatology

A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals

(2015) N.T. Krarup et al.   ATHEROSCLEROSIS

The Role of Autophagy in Lupus Nephritis

(2015) Linlin Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

(2015) James Bentham et al.   NATURE GENETICS

Genetic Factors in Systemic Lupus Erythematosus: Contribution to Disease Phenotype

(2015) Fulvia Ceccarelli et al.   Journal of Immunology Research

Factors associated with damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort

(2014) Ian N Bruce et al.   ANNALS OF THE RHEUMATIC DISEASES

Lack of replication of higher genetic risk load in men than in women with systemic lupus erythematosus

(2014) Elisa Alonso-Perez et al.   ARTHRITIS RESEARCH & THERAPY

Late-onset systemic lupus erythematosus: clinical features, course, and prognosis

(2013) Aleksandra Tomic-Lucic et al.   CLINICAL RHEUMATOLOGY

Association of STAT4 Polymorphism with Severe Renal Insufficiency in Lupus Nephritis

(2013) Karin Bolin et al.   PLoS One

HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus

(2012) Emeli Lundström et al.   ANNALS OF THE RHEUMATIC DISEASES

Predictors of organ damage in systemic lupus erythematosus: The Hopkins Lupus Cohort

(2012) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

Risk factors for cardiovascular mortality in patients with systemic lupus erythematosus, a prospective cohort study

(2012) Johanna T Gustafsson et al.   ARTHRITIS RESEARCH & THERAPY

The genetics of systemic lupus erythematosus and implications for targeted therapy

(2011) A. L. Sestak et al.   ANNALS OF THE RHEUMATIC DISEASES

Analysis of autosomal genes reveals gene–sex interactions and higher total genetic risk in men with systemic lupus erythematosus

(2011) Travis Hughes et al.   ANNALS OF THE RHEUMATIC DISEASES

Risk Alleles for Systemic Lupus Erythematosus in a Large Case-Control Collection and Associations with Clinical Subphenotypes

(2011) Kimberly E. Taylor et al.   PLoS Genetics

A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus

(2009) E. Svenungsson et al.   ANNALS OF THE RHEUMATIC DISEASES

A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5

(2008) S. Sigurdsson et al.   HUMAN MOLECULAR GENETICS

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

(2008) John B Harley et al.   NATURE GENETICS

Association of Systemic Lupus Erythematosus withC8orf13–BLKandITGAM–ITGAX

(2008) Geoffrey Hom et al.   NEW ENGLAND JOURNAL OF MEDICINE