Anti-proliferative effect of 23,24-dihydrocucurbitacin F on human prostate cancer cells through induction of actin aggregation and cofilin-actin rod formation

Cucurbitacin B induces rapid depletion of the G-actin pool through reactive oxygen species-dependent actin aggregation in melanoma cells

(2011) Y. Zhang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Histone deacetylase inhibitor valproic acid sensitizes B16F10 melanoma cells to cucurbitacin B treatment

(2011) Dongyun Ouyang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Cucurbitacin IIa: a novel class of anti-cancer drug inducing non-reversible actin aggregation and inhibiting survivin independent of JAK2/STAT3 phosphorylation

(2011) C Boykin et al.   BRITISH JOURNAL OF CANCER

Cofilin Aggregation Blocks Intracellular Trafficking and Induces Synaptic Loss in Hippocampal Neurons

(2011) Joseph Cichon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Valproic acid synergistically enhances the cytotoxicity of gossypol in DU145 prostate cancer cells: An iTRTAQ-based quantitative proteomic analysis

(2011) Dong-yun Ouyang et al.   Journal of Proteomics

Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation

(2011) Richard C Davis et al.   Molecular Neurodegeneration

The induction of G2/M cell-cycle arrest and apoptosis by cucurbitacin E is associated with increased phosphorylation of eIF2α in leukemia cells

(2010) Yanchun Li et al.   ANTI-CANCER DRUGS

Cucurbitacin E as a new inhibitor of cofilin phosphorylation in human leukemia U937 cells

(2010) Souichi Nakashima et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

JSI-124 inhibits glioblastoma multiforme cell proliferation through G2/M cell cycle arrest and apoptosis augmentation

(2010) Yuhang Su et al.   CANCER BIOLOGY & THERAPY

ADF/Cofilin-Actin Rods in Neurodegenerative Diseases

(2010) J.R. Bamburg et al.   Current Alzheimer Research

Cucurbitacin I Inhibits Cell Motility by Indirectly Interfering with Actin Dynamics

(2010) David A. Knecht et al.   PLoS One

Cucurbitacin I elicits anoikis sensitization, inhibits cellular invasion and in vivo tumor formation ability of nasopharyngeal carcinoma cells

(2009) Vivian W.Y. Lui et al.   CARCINOGENESIS

Cucurbitacin B induces G2arrest and apoptosisviaa reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells

(2009) Shusuke Yasuda et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Chronophin Mediates an ATP-Sensing Mechanism for Cofilin Dephosphorylation and Neuronal Cofilin-Actin Rod Formation

(2008) Timothy Y. Huang et al.   DEVELOPMENTAL CELL

CDK Inhibitors: Cell Cycle Regulators and Beyond

(2008) Arnaud Besson et al.   DEVELOPMENTAL CELL

Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme

(2008) Dong Yin et al.   INTERNATIONAL JOURNAL OF CANCER

Actin-Aggregating Cucurbitacins fromPhysocarpus capitatus

(2008) Katherine N. Maloney et al.   JOURNAL OF NATURAL PRODUCTS

Cucurbitacin B induces differentiation, cell cycle arrest, and actin cytoskeletal alterations in myeloid leukemia cells

(2008) Talin Haritunians et al.   LEUKEMIA RESEARCH