Multisubstituted pyrazole synthesis via [3 + 2] cycloaddition/rearrangement/N H insertion cascade reaction of α-diazoesters and ynones

Alkynes and Nitrogen Compounds: Useful Substrates for the Synthesis of Pyrazoles

(2020) Jose Neto et al.   CHEMISTRY-A EUROPEAN JOURNAL

Intramolecular Cyclization of Vinyldiazoacetates as a Versatile Route to Substituted Pyrazoles

(2020) Ivan Vilotijevic et al.   SYNLETT

Synthesis, structure-activity relationship and trypanocidal activity of pyrazole-imidazoline and new pyrazole-tetrahydropyrimidine hybrids as promising chemotherapeutic agents for Chagas disease

(2019) M.E. Monteiro et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Elexacaftor–Tezacaftor–Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele

(2019) Peter G. Middleton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review

(2018) Khalid Karrouchi et al.   MOLECULES

Transition-Metal-Free [3 + 2] Cycloaddition of Nitroolefins and Diazoacetonitrile: A Facile Access to Multisubstituted Cyanopyrazoles

(2018) Zhen Chen et al.   ORGANIC LETTERS

Substrate-Controlled Synthesis of Spirocyclopropylpyrazolones and Bicyclic 4,5-Dihydropyrazoles from 1,2-Diaza-1,3-dienes with Sulfur Ylides

(2018) Jiaan Shao et al.   ORGANIC LETTERS

Chiral Lewis acid-catalyzed enantioselective cyclopropanation and C–H insertion reactions of vinyl ketones with α-diazoesters

(2018) Peng Zhao et al.   CHEMICAL COMMUNICATIONS

Phosphine-Catalyzed [3 + 2] Cycloaddition Reaction of α-Diazoacetates and β-Trifluoromethyl Enones: A Facile Access to Multisubstituted 4-(Trifluoromethyl)pyrazolines

(2018) Yongfeng Li et al.   ORGANIC LETTERS

Genetic determinants of response to fibroblast growth factor receptor inhibitors in solid tumours

(2017) Laura Leroy et al.   EUROPEAN JOURNAL OF CANCER

Safety, pharmacokinetic, and pharmacodynamics of erdafitinib, a pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor, in patients with advanced or refractory solid tumors

(2017) Tomohiro Nishina et al.   INVESTIGATIONAL NEW DRUGS

Review: biologically active pyrazole derivatives

(2017) Anam Ansari et al.   NEW JOURNAL OF CHEMISTRY

The therapeutic voyage of pyrazole and its analogs: A review

(2016) Mohemmed Faraz Khan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Modern Organic Synthesis with α-Diazocarbonyl Compounds

(2015) Alan Ford et al.   CHEMICAL REVIEWS

New Life for Diazoacetonitrile (N2CHCN): in situ Generation and Practical Synthesis of CN-Pyrazoles

(2015) Pavel K. Mykhailiuk   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Arylglyoxals in Synthesis of Heterocyclic Compounds

(2013) Bagher Eftekhari-Sis et al.   CHEMICAL REVIEWS

Environment-friendly Synthesis of Bioactive Pyrazoles

(2013) Lucas Pizzuti et al.   CURRENT ORGANIC CHEMISTRY

Synthesis, characterization, cytotoxicity and antibacterial activity of an anthracenyl-linked bis(pyrazolyl)methane ligand and its zinc(II) complexes

(2013) Ban-Feng Ruan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Preparation and Chemistry of 3/5-Halogenopyrazoles

(2012) Yves L. Janin   CHEMICAL REVIEWS

Highly Selective Primary Alkoxycarboxylation and Esterification of Unprotected Pyranose Derivatives Mediated by Scandium(III) Triflate Catalysis

(2012) Michael S. McClure et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

In Vitro and in Vivo Trypanosomicidal Activity of Pyrazole-Containing Macrocyclic and Macrobicyclic Polyamines: Their Action on Acute and Chronic Phases of Chagas Disease

(2012) Manuel Sánchez-Moreno et al.   JOURNAL OF MEDICINAL CHEMISTRY

Diazo compounds as highly tunable reactants in 1,3-dipolar cycloaddition reactions with cycloalkynes

(2012) Nicholas A. McGrath et al.   Chemical Science

Synthesis and antileishmanial evaluation of 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-1H-pyrazole derivatives

(2011) Maurício S. dos Santos et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles

(2011) Santos Fustero et al.   CHEMICAL REVIEWS

Three-Component Reaction Using the Bestmann-Ohira Reagent: A Regioselective Synthesis of Phosphonyl Pyrazole Rings

(2010) Kishor Mohanan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

1,3-Dipolar Cycloaddition Reactions of Vinylidenecyclopropane-Diesters with Aromatic Diazomethanes Generated in Situ

(2010) Lei Wu et al.   JOURNAL OF ORGANIC CHEMISTRY

Lewis acid- and/or Lewis base-catalyzed [3+2] cycloaddition reaction: synthesis of pyrazoles and pyrazolines

(2008) Palakodety Radha Krishna et al.   TETRAHEDRON LETTERS