A MIF‐Derived Cyclopeptide that Inhibits MIF Binding and Atherogenic Signaling via the Chemokine Receptor CXCR2

Macrophage Migration Inhibitory Factor (MIF)-Based Therapeutic Concepts in Atherosclerosis and Inflammation

(2019) Dzmitry Sinitski et al.   THROMBOSIS AND HAEMOSTASIS

The immunobiology of MIF: function, genetics and prospects for precision medicine

(2019) Insoo Kang et al.   Nature Reviews Rheumatology

PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function

(2019) Mariaelvy Bianchini et al.   Science Immunology

Designed Macrocyclic Peptides as Nanomolar Amyloid Inhibitors Based on Minimal Recognition Elements

(2018) Anna Spanopoulou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4

(2018) Michael Lacy et al.   Scientific Reports

MIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics

(2017) Pathricia V. Tilstam et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Current State of Peptide Drug Discovery: Back to the Future?

(2017) Antoine Henninot et al.   JOURNAL OF MEDICINAL CHEMISTRY

New paradigms in chemokine receptor signal transduction: Moving beyond the two-site model

(2016) Andrew B. Kleist et al.   BIOCHEMICAL PHARMACOLOGY

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives

(2015) Lukas Pawig et al.   Frontiers in Immunology

Selectively N-Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self-Assembly of Both IAPP and Aβ40

(2013) Li-Mei Yan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Arrest Functions of the MIF Ligand/Receptor Axes in Atherogenesis

(2013) Sabine Tillmann et al.   Frontiers in Immunology

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Macrophage migration inhibitory factor (MIF) exerts antifibrotic effects in experimental liver fibrosis via CD74

(2011) D. Heinrichs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism

(2010) Sandra Kraemer et al.   FASEB JOURNAL

Deconvolution of complex G protein–coupled receptor signaling in live cells using dynamic mass redistribution measurements

(2010) Ralf Schröder et al.   NATURE BIOTECHNOLOGY

Macrophage Migration Inhibitory Factor in Cardiovascular Disease

(2008) Alma Zernecke et al.   CIRCULATION

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart

(2008) Edward J. Miller et al.   NATURE

Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment

(2008) C. Weber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA