Iron overload adversely effects bone marrow haematogenesis via SIRT-SOD2-mROS in a process ameliorated by curcumin

Astragalus Polysaccharide Attenuated Iron Overload-Induced Dysfunction of Mesenchymal Stem Cells via Suppressing Mitochondrial ROS

(2016) Fan Yang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Momordin Ic couples apoptosis with autophagy in human hepatoblastoma cancer cells by reactive oxygen species (ROS)-mediated PI3K/Akt and MAPK signaling pathways

(2016) Yashi Mi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Efficacy and safety of deferasirox estimated by serum ferritin and labile plasma iron levels in patients with aplastic anemia, myelodysplastic syndrome, or acute myeloid leukemia with transfusional iron overload

(2015) Il-Hwan Kim et al.   TRANSFUSION

Oxidative stress and autophagy: the clash between damage and metabolic needs

(2014) G Filomeni et al.   CELL DEATH AND DIFFERENTIATION

Deferasirox for transfusion-dependent patients with myelodysplastic syndromes: safety, efficacy, and beyond (GIMEMA MDS0306 Trial)

(2014) Emanuele Angelucci et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Age-Related Decrease in the Mitochondrial Sirtuin Deacetylase Sirt3 Expression Associated with ROS Accumulation in the Auditory Cortex of the Mimetic Aging Rat Model

(2014) Lingling Zeng et al.   PLoS One

Metabolism leaves its mark on the powerhouse: recent progress in post-translational modifications of lysine in mitochondria

(2014) Kyriakos N. Papanicolaou et al.   Frontiers in Physiology

The emerging role of acetylation in the regulation of autophagy

(2013) Ágnes Bánréti et al.   Autophagy

Bioenergetic and autophagic control by Sirt3 in response to nutrient deprivation in mouse embryonic fibroblasts

(2013) Qiuli Liang et al.   BIOCHEMICAL JOURNAL

Free iron catalyzes oxidative damage to hematopoietic cells/mesenchymal stem cellsin vitroand suppresses hematopoiesis in iron overload patients

(2013) Wenyi Lu et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Assessment of free radicals scavenging activity of seven natural pigments and protective effects in AAPH-challenged chicken erythrocytes

(2013) Jingfei Zhang et al.   FOOD CHEMISTRY

Oxidative Stress Levels in Myelodysplastic Syndrome Patients: Their Relationship to Serum Ferritin and Haemoglobin Values

(2013) K Saigo et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage

(2012) Jing Han et al.   Autophagy

SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging

(2012) Albert Giralt et al.   BIOCHEMICAL JOURNAL

SIRT3 regulation of mitochondrial oxidative stress

(2012) Alexandra S. Bause et al.   EXPERIMENTAL GERONTOLOGY

Mitochondrial dysfunction mediated cisplatin induced toxicity: Modulatory role of curcumin

(2012) Mohammad Waseem et al.   FOOD AND CHEMICAL TOXICOLOGY

Exploring the electrostatic repulsion model in the role of Sirt3 in directing MnSOD acetylation status and enzymatic activity

(2012) Yueming Zhu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice

(2012) Heng Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Redox regulation of stem/progenitor cells and bone marrow niche

(2012) Norifumi Urao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hematologic responses to deferasirox therapy in transfusion-dependent patients with myelodysplastic syndromes

(2012) N. Gattermann et al.   HAEMATOLOGICA

Deferasirox Reduces Serum Ferritin and Labile Plasma Iron in RBC Transfusion–Dependent Patients With Myelodysplastic Syndrome

(2012) Alan F. List et al.   JOURNAL OF CLINICAL ONCOLOGY

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

(2012) Alexander S. Hebert et al.   MOLECULAR CELL

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS

(2011) Yaohui Chen et al.   EMBO REPORTS

Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation

(2010) Xiaolei Qiu et al.   Cell Metabolism

Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells

(2010) Donald J. Messner et al.   LIVER INTERNATIONAL

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

(2010) Randa Tao et al.   MOLECULAR CELL

Iron chelation therapy associated with improvement of hematopoiesis in transfusion-dependent patients

(2010) Esther Natalie Oliva et al.   TRANSFUSION

Mitochondrial Reactive Oxygen Species Production in Excitable Cells: Modulators of Mitochondrial and Cell Function

(2009) David F. Stowe et al.   ANTIOXIDANTS & REDOX SIGNALING

Deferasirox Treatment Improved the Hemoglobin Level and Decreased Transfusion Requirements in Four Patients with the Myelodysplastic Syndrome and Primary Myelofibrosis

(2008) E. Messa et al.   ACTA HAEMATOLOGICA

Curcumin and the cellular stress response in free radical-related diseases

(2008) Vittorio Calabrese et al.   MOLECULAR NUTRITION & FOOD RESEARCH