Age-Related Decrease in the Mitochondrial Sirtuin Deacetylase Sirt3 Expression Associated with ROS Accumulation in the Auditory Cortex of the Mimetic Aging Rat Model

Reactive Oxygen Species: Stuck in the Middle of Neurodegeneration

(2017) David A. Patten et al.   JOURNAL OF ALZHEIMERS DISEASE

Reduced mitochondrial function in obesity-associated fatty liver: SIRT3 takes on the fat

(2016) Mahua Choudhury et al.   Aging-US

Role of Mitochondria in Neurodegenerative Diseases: Mitochondria as a Therapeutic Target in Alzheimer's Disease

(2016) P. Hemachandra Reddy   CNS SPECTRUMS

SIRT3 Reverses Aging-Associated Degeneration

(2013) Katharine Brown et al.   Cell Reports

SIRT3, a pivotal actor in mitochondrial functions: metabolism, cell death and aging

(2012) Albert Giralt et al.   BIOCHEMICAL JOURNAL

Regulation of mitochondrial FoF1ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977bp deletion of mitochondrial DNA

(2012) Yu-Ting Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

SIRT3 protects from hypoxia and staurosporine-mediated cell death by maintaining mitochondrial membrane potential and intracellular pH

(2012) L Pellegrini et al.   CELL DEATH AND DIFFERENTIATION

SIRT3 gene expression: A link between inherited mitochondrial DNA variants and oxidative stress

(2012) Patrizia D'Aquila et al.   GENE

Central Presbycusis: A Review and Evaluation of the Evidence

(2012) Larry E. Humes et al.   Journal of the American Academy of Audiology

CNS SIRT3 Expression Is Altered by Reactive Oxygen Species and in Alzheimer’s Disease

(2012) Heather J. M. Weir et al.   PLoS One

Metformin Reduces Hepatic Expression of SIRT3, the Mitochondrial Deacetylase Controlling Energy Metabolism

(2012) Marcin Buler et al.   PLoS One

Mitochondrial sirtuins: regulators of protein acylation and metabolism

(2012) Wenjuan He et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mitochondrial Metabolism, Sirtuins, and Aging

(2012) M. N. Sack et al.   Cold Spring Harbor Perspectives in Biology

Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: Implications for early intervention and therapeutics

(2011) Peizhong Mao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial DNA deletions and differential mitochondrial DNA content in Rhesus monkeys: Implications for aging

(2011) Peizhong Mao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS

(2011) Yaohui Chen et al.   EMBO REPORTS

Pathogenesis of presbycusis in animal models: A review

(2011) Anna R. Fetoni et al.   EXPERIMENTAL GERONTOLOGY

Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA

(2011) Zsolt Radak et al.   MOLECULAR ASPECTS OF MEDICINE

Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity

(2011) Lydia W. S. Finley et al.   PLoS One

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

(2011) E. Jing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation

(2010) Xiaolei Qiu et al.   Cell Metabolism

SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production

(2010) Tadahiro Shimazu et al.   Cell Metabolism

Neuroprotective strategies involving ROS in Alzheimer disease

(2010) Magali Dumont et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial oxidative damage and apoptosis in age-related hearing loss

(2010) Shinichi Someya et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Increased mitochondrial DNA damage and decreased base excision repair in the auditory cortex of d-galactose-induced aging rats

(2010) Bei Chen et al.   MOLECULAR BIOLOGY REPORTS

Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress

(2010) Randa Tao et al.   MOLECULAR CELL

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

(2010) Xingxing Kong et al.   PLoS One

Regulation of superoxide dismutase genes: Implications in disease

(2009) Lu Miao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Quantification of the mitochondrial DNA common deletion in presbycusis

(2009) Adam Markaryan et al.   LARYNGOSCOPE

Tissue Inhibitor of Metalloproteinase 3 Suppresses Tumor Angiogenesis in Matrix Metalloproteinase 2-Down-regulated Lung Cancer

(2008) C. Chetty et al.   CANCER RESEARCH

The 4977bp deletion of mitochondrial DNA in human skeletal muscle, heart and different areas of the brain: A useful biomarker or more?

(2008) Christoph Meissner et al.   EXPERIMENTAL GERONTOLOGY

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA