The emerging role of acetylation in the regulation of autophagy

Histone deacetylase 6 functions as a tumor suppressor by activating c-Jun NH2-terminal kinase-mediated beclin 1-dependent autophagic cell death in liver cancer

(2012) Kwang Hwa Jung et al.   HEPATOLOGY

A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics

(2012) Ellen Van Damme et al.   International Journal of Biological Sciences

Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity

(2012) Jae-Kyo Jeong et al.   NEUROBIOLOGY OF AGING

HDAC1 Inactivation Induces Mitotic Defect and Caspase-Independent Autophagic Cell Death in Liver Cancer

(2012) Hong Jian Xie et al.   PLoS One

Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice

(2012) V. Moresi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function and Molecular Mechanism of Acetylation in Autophagy Regulation

(2012) C. Yi et al.   SCIENCE

GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy

(2012) S.-Y. Lin et al.   SCIENCE

Longevity-relevant regulation of autophagy at the level of the acetylproteome

(2011) Guillermo Mariño et al.   Autophagy

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

(2011) Guri Tzivion et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Selective autophagy in the maintenance of cellular homeostasis in aging organisms

(2011) Vanessa M. Hubbard et al.   BIOGERONTOLOGY

Autophagy in the Cellular Energetic Balance

(2011) Rajat Singh et al.   Cell Metabolism

The Microbiome and Butyrate Regulate Energy Metabolism and Autophagy in the Mammalian Colon

(2011) Dallas R. Donohoe et al.   Cell Metabolism

Deciphering the Role of Forkhead Transcription Factors in Cancer Therapy

(2011) Jer-Yen Yang et al.   CURRENT DRUG TARGETS

Regulation of Foxo-Dependent Transcription by Post-Translational Modifications

(2011) Marco Boccitto et al.   CURRENT DRUG TARGETS

Autophagic and Apoptotic Effects of HDAC Inhibitors on Cancer Cells

(2011) Hidemi Rikiishi   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome

(2011) Eugenia Morselli et al.   JOURNAL OF CELL BIOLOGY

SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL

(2011) Partha Chakrabarti et al.   JOURNAL OF LIPID RESEARCH

Autophagy and disease: always two sides to a problem

(2011) Sunandini Sridhar et al.   JOURNAL OF PATHOLOGY

HDACs link the DNA damage response, processing of double-strand breaks and autophagy

(2011) Thomas Robert et al.   NATURE

Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines

(2011) J. Fu et al.   NEURO-ONCOLOGY

Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy

(2011) D. J. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation

(2011) David G. McEwan et al.   TRENDS IN CELL BIOLOGY

Regulation of lipid droplets by autophagy

(2011) Hanqing Dong et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cigarette smoke-induced autophagy is regulated by SIRT1–PARP-1-dependent mechanism: Implication in pathogenesis of COPD

(2010) Jae-woong Hwang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Quality control autophagy: A joint effort of ubiquitin, protein deacetylase and actin cytoskeleton

(2010) Joo-Yong Lee et al.   Autophagy

p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy

(2010) Terje Høyvarde Clausen et al.   Autophagy

Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

(2010) Yuan-Ling Liu et al.   Autophagy

microRNA-dependent modulation of histone acetylation in Waldenstrom macroglobulinemia

(2010) A. M. Roccaro et al.   BLOOD

Acetylated microtubules are required for fusion of autophagosomes with lysosomes

(2010) Rui Xie et al.   BMC CELL BIOLOGY

Effects of Longevinex (modified resveratrol) on cardioprotection and its mechanisms of action

(2010) Subhendu Mukherjee et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Autophagic Survival in Resistance to Histone Deacetylase Inhibitors: Novel Strategies to Treat Malignant Peripheral Nerve Sheath Tumors

(2010) G. Lopez et al.   CANCER RESEARCH

HDAC6 a new cellular stress surveillance factor

(2010) Patrick Matthias et al.   CELL CYCLE

MYST-family histone acetyltransferases: beyond chromatin

(2010) Vasileia Sapountzi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

A Genome-Wide siRNA Screen Reveals Multiple mTORC1 Independent Signaling Pathways Regulating Autophagy under Normal Nutritional Conditions

(2010) Marta M. Lipinski et al.   DEVELOPMENTAL CELL

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

(2010) Joo-Yong Lee et al.   EMBO JOURNAL

Starvation-induced Hyperacetylation of Tubulin Is Required for the Stimulation of Autophagy by Nutrient Deprivation

(2010) Camille Geeraert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Tale of Protein Lysine Acetylation in the Cytoplasm

(2010) Karin Sadoul et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

(2010) Shinji Kume et al.   JOURNAL OF CLINICAL INVESTIGATION

Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility

(2010) Nadia Cernotta et al.   MOLECULAR BIOLOGY OF THE CELL

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

ARD1 Stabilization of TSC2 Suppresses Tumorigenesis Through the mTOR Signaling Pathway

(2010) H.-P. Kuo et al.   Science Signaling

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation

(2009) Hyunkyung Jeong et al.   CELL

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

FoxO Transcription Factors Promote Autophagy in Cardiomyocytes

(2009) Arunima Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Autophagy by the p300 Acetyltransferase

(2009) In Hye Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleocytoplasmic Shuttling of p62/SQSTM1 and Its Role in Recruitment of Nuclear Polyubiquitinated Proteins to Promyelocytic Leukemia Bodies

(2009) Serhiy Pankiv et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Inhibition of histone deacetylase1 induces autophagy

(2008) Meeyeon Oh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Acetylation of Sirt2 by p300 attenuates its deacetylase activity

(2008) Younho Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of the Aggresome Pathway in Cancer: Targeting Histone Deacetylase 6-Dependent Protein Degradation

(2008) A. Rodriguez-Gonzalez et al.   CANCER RESEARCH

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Dynein-dependent Movement of Autophagosomes Mediates Efficient Encounters with Lysosomes

(2008) Shunsuke Kimura et al.   CELL STRUCTURE AND FUNCTION

Induction of autophagy in malignant rhabdoid tumor cells by the histone deacetylase inhibitor FK228 through AIF translocation

(2008) Motonobu Watanabe et al.   INTERNATIONAL JOURNAL OF CANCER

Antitumor effects of a novel sulfur-containing hydroxamate histone deacetylase inhibitor H40

(2008) Juan Long et al.   INTERNATIONAL JOURNAL OF CANCER

SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway

(2008) A Hrzenjak et al.   JOURNAL OF PATHOLOGY

Arp2 Links Autophagic Machinery with the Actin Cytoskeleton

(2008) Iryna Monastyrska et al.   MOLECULAR BIOLOGY OF THE CELL

SIRT2 Suppresses Adipocyte Differentiation by Deacetylating FOXO1 and Enhancing FOXO1's Repressive Interaction with PPARγ

(2008) Fei Wang et al.   MOLECULAR BIOLOGY OF THE CELL

The SIRT2 Deacetylase Regulates Autoacetylation of p300

(2008) Joshua C. Black et al.   MOLECULAR CELL

Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications

(2008) Xiang-Jiao Yang et al.   MOLECULAR CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Picky Eater: Exploring the Mechanisms of Selective Autophagy in Human Pathologies

(2008) Aniek van der Vaart et al.   TRAFFIC

The Itinerary of Autophagosomes: From Peripheral Formation to Kiss-and-Run Fusion with Lysosomes

(2008) Luca Jahreiss et al.   TRAFFIC