Chitooligosaccharides inhibit tumor progression and induce autophagy through the activation of the p53/mTOR pathway in osteosarcoma

Chitosan oligosaccharides induce apoptosis in human renal carcinoma via ROS-dependent ER stress

(2019) Xingchen Zhai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Easy and effective method to generate endotoxin-free chitosan particles for immunotoxicology and immunopharmacology studies

(2019) Filipa Lebre et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort

(2019) Sigbjørn Smeland et al.   EUROPEAN JOURNAL OF CANCER

Novel biocompatible poly(acrylamide)-grafted-dextran hydrogels: Synthesis, characterization and biomedical applications

(2019) Sudha B. Patil et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Chitooligosaccharides display anti-tumor effects against human cervical cancer cells via the apoptotic and autophagic pathways

(2019) Mengyao Zhao et al.   CARBOHYDRATE POLYMERS

Chitosan oligosaccharides with degree of polymerization 2–6 induces apoptosis in human colon carcinoma HCT116 cells

(2018) Pan Zou et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Activation of the p53 pathway with digiferrol isolated from Rubia philippinensis induces cell cycle arrest, apoptosis, and autophagy in colon cancer cells

(2018) Younju An et al.   FOOD AND CHEMICAL TOXICOLOGY

Biochemical properties of a novel chitosanase from Bacillus amyloliquefaciens and its use in membrane reactor

(2018) Zhen Qin et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Long noncoding RNA DANCR, working as a competitive endogenous RNA, promotes ROCK1-mediated proliferation and metastasis via decoying of miR-335-5p and miR-1972 in osteosarcoma

(2018) Yong Wang et al.   Molecular Cancer

Pre-Harvest Treatment of Chitosan Oligosaccharides Improved Strawberry Fruit Quality

(2018) Yanqiu He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Synergistic inhibitory effects of capsaicin combined with cisplatin on human osteosarcoma in culture and in xenografts

(2018) Yang Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma

(2017) Gangyang Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chitosan centered bionanocomposites for medical specialty and curative applications: A review

(2017) Mudasir Ahmad et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Involvement of PKA signalling in anti-inflammatory effects of chitosan oligosaccharides in IPEC-J2 porcine epithelial cells

(2017) J. W. Yang et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Chitosan oligosaccharide: Biological activities and potential therapeutic applications

(2017) Chatchai Muanprasat et al.   PHARMACOLOGY & THERAPEUTICS

Effect of the molecular weight of water-soluble chitosan on its fat-/cholesterol-binding capacities and inhibitory activities to pancreatic lipase

(2017) Qiu Jin et al.   PeerJ

Physicochemical, antioxidant, and antimicrobial properties of chitooligosaccharides produced using three different enzyme treatments

(2017) Thunnop Laokuldilok et al.   Food Bioscience

The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches

(2016) Andreas C. Joerger et al.   Annual Review of Biochemistry

Application of chitooligosaccharides as antioxidants in beer to improve the flavour stability by protecting against beer staling during storage

(2016) Fan Yang et al.   BIOTECHNOLOGY LETTERS

Chitosan grafted monomethyl fumaric acid as a potential food preservative

(2016) Imran Khan et al.   CARBOHYDRATE POLYMERS

Chitosan oligosaccharide suppresses tumor progression in a mouse model of colitis-associated colorectal cancer through AMPK activation and suppression of NF-κB and mTOR signaling

(2016) Tharinee Mattaveewong et al.   CARBOHYDRATE POLYMERS

Survival or death: a dual role for autophagy in stress-induced pericyte loss in diabetic retinopathy

(2016) Dongxu Fu et al.   DIABETOLOGIA

Effect of Chitosan Properties on Immunoreactivity

(2016) Sruthi Ravindranathan et al.   Marine Drugs

Chitooligosaccharides promote radiosensitivity in colon cancer line SW480

(2016) Fu-Shi Han   WORLD JOURNAL OF GASTROENTEROLOGY

The dual role of autophagy under hypoxia-involvement of interaction between autophagy and apoptosis

(2015) Mengmeng Li et al.   APOPTOSIS

Chitosan Oligosaccharide Reduces Intestinal Inflammation That Involves Calcium-Sensing Receptor (CaSR) Activation in Lipopolysaccharide (LPS)-Challenged Piglets

(2015) Bo Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Osteosarcoma: Current Treatment and a Collaborative Pathway to Success

(2015) Michael S. Isakoff et al.   JOURNAL OF CLINICAL ONCOLOGY

Activation of p53 with Ilimaquinone and Ethylsmenoquinone, Marine Sponge Metabolites, Induces Apoptosis and Autophagy in Colon Cancer Cells

(2015) Hyun-Young Lee et al.   Marine Drugs

Hydrogen peroxide treated graphene as an effective nanosheet filler for separation application

(2015) Dharupaneedi P. Suhas et al.   RSC Advances

Time-trends on incidence and survival in a nationwide and unselected cohort of patients with skeletal osteosarcoma

(2014) Kjetil Berner et al.   ACTA ONCOLOGICA

Review of the Molecular Pathogenesis of Osteosarcoma

(2014) Jin-Peng He et al.   Asian Pacific Journal of Cancer Prevention

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Functionalized Graphene Sheets Embedded in Chitosan Nanocomposite Membranes for Ethanol and Isopropanol Dehydration via Pervaporation

(2014) Suhas P. Dharupaneedi et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Toll like receptor 4 (TLR4) mediates the stimulating activities of chitosan oligosaccharide on macrophages

(2014) Pei Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Endotoxins affect diverse biological activity of chitosans in matters of hemocompatibility and cytocompatibility

(2014) Andrea Nolte et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

PI3K and cancer: lessons, challenges and opportunities

(2014) David A. Fruman et al.   NATURE REVIEWS DRUG DISCOVERY

Chitooligosaccharides inhibit ethanol-induced oxidative stress via activation of Nrf2 and reduction of MAPK phosphorylation

(2014) ZHIGUO LUO et al.   ONCOLOGY REPORTS

Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma

(2014) Jennifer A. Perry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy regulation by nutrient signaling

(2013) Ryan C Russell et al.   CELL RESEARCH

The machinery of macroautophagy

(2013) Yuchen Feng et al.   CELL RESEARCH

The evolving classification of soft tissue tumours - an update based on the new 2013 WHO classification

(2013) Christopher D M Fletcher   HISTOPATHOLOGY

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

Differential functional effects of biomaterials on dendritic cell maturation

(2012) Jaehyung Park et al.   Acta Biomaterialia

Endotoxins affect bioactivity of chitosan derivatives in cultures of bone marrow-derived human mesenchymal stem cells

(2012) Ramona Lieder et al.   Acta Biomaterialia

HMGB1 Promotes Drug Resistance in Osteosarcoma

(2011) J. Huang et al.   CANCER RESEARCH

Chitosan oligosaccharides inhibit LPS-induced over-expression of IL-6 and TNF-α in RAW264.7 macrophage cells through blockade of mitogen-activated protein kinase (MAPK) and PI3K/Akt signaling pathways

(2011) Pan Ma et al.   CARBOHYDRATE POLYMERS

Molecular alterations as target for therapy in metastatic osteosarcoma: a review of literature

(2011) J. PosthumaDeBoer et al.   CLINICAL & EXPERIMENTAL METASTASIS

Effects of the Molecular Weight and the Degree of Deacetylation of Chitosan Oligosaccharides on Antitumor Activity

(2011) Jae Kweon Park et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chitosan—A versatile semi-synthetic polymer in biomedical applications

(2011) M. Dash et al.   PROGRESS IN POLYMER SCIENCE

Osteosarcoma incidence and survival rates from 1973 to 2004

(2009) Lisa Mirabello et al.   CANCER

Inhibitory effects of chitooligosaccharides on tumor growth and metastasis

(2009) Kun-Te Shen et al.   FOOD AND CHEMICAL TOXICOLOGY