Different T-cell subsets in glioblastoma multiforme and targeted immunotherapy

Elevated lymphocyte specific protein 1 expression is involved in the regulation of leukocyte migration and immunosuppressive microenvironment in glioblastoma

(2020) Jing-Yuan Cao et al.   Aging-US

Multiparametric MRI for early identification of therapeutic response in recurrent glioblastoma treated with immune checkpoint inhibitors

(2020) Joseph Song et al.   NEURO-ONCOLOGY

Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics

(2020) Teresa G Krieger et al.   NEURO-ONCOLOGY

The TCR Repertoire Reconstitution in Multiple Sclerosis: Comparing One-Shot and Continuous Immunosuppressive Therapies

(2020) Roberta Amoriello et al.   Frontiers in Immunology

Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy

(2019) Pamela C. Rosato et al.   Nature Communications

Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma

(2019) Junfei Zhao et al.   NATURE MEDICINE

Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma

(2019) Kurt A. Schalper et al.   NATURE MEDICINE

Challenges and potential of PD-1/PD-L1 checkpoint blockade immunotherapy for glioblastoma

(2019) Xin Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Glial TLR2‐driven innate immune responses and CD8 + T cell activation against brain tumor

(2019) Chi Young Chang et al.   GLIA

PD-1/PD-L1 immune-checkpoint inhibitors in glioblastoma: A concise review

(2019) Mario Caccese et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Role of Apelin in Glioblastoma Vascularization and Invasion after Anti-VEGF Therapy: What Is the Impact on the Immune System?

(2019) Zohreh Amoozgar et al.   CANCER RESEARCH

Contact-dependent killing by cytotoxic T lymphocytes is insufficient for EL4 tumor regression in vivo

(2019) Richard J Beck et al.   CANCER RESEARCH

Features and therapeutic potential of T-cell receptors in high-grade glioma

(2019) Jie-Lin Zhang et al.   CHINESE MEDICAL JOURNAL

HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma

(2019) Jason Miska et al.   Cell Reports

Distinct phenotype and function of circulating Vδ1+ and Vδ2+ γδT-cells in acute and chronic hepatitis B

(2019) Kyong-Mi Chang et al.   PLoS Pathogens

Impaired circulating myeloid CD1c+ dendritic cell function in human glioblastoma is restored by p38 inhibition – implications for the next generation of DC vaccines

(2019) Jason Adhikaree et al.   OncoImmunology

The Evolving Role of CD8+CD28− Immunosenescent T Cells in Cancer Immunology

(2019) Wei X. Huff et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

(2019) Bracha Shraibman et al.   MOLECULAR & CELLULAR PROTEOMICS

Author Correction: Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39

(2019) Maisa C. Takenaka et al.   NATURE NEUROSCIENCE

Increased Antiangiogenic Effect by Blocking CCL2-dependent Macrophages in a Rodent Glioblastoma Model: Correlation Study with Dynamic Susceptibility Contrast Perfusion MRI

(2019) Hye Rim Cho et al.   Scientific Reports

NKG2D controls natural reactivity of Vγ9Vδ2 T lymphocytes against mesenchymal glioblastoma cells

(2019) Cynthia Chauvin et al.   CLINICAL CANCER RESEARCH

Molecular targeted therapy of glioblastoma

(2019) Emilie Le Rhun et al.   CANCER TREATMENT REVIEWS

Immune landscapes associated with different glioblastoma molecular subtypes

(2019) Maria Martinez-Lage et al.   Acta Neuropathologica Communications

Unraveling the Complex Interplay Between T Cell Metabolism and Function

(2018) Ramon I. Klein Geltink et al.   Annual Review of Immunology

T-cell Dysfunction in Glioblastoma: Applying a New Framework

(2018) Karolina I. Woroniecka et al.   CLINICAL CANCER RESEARCH

Association between Th1/Th2 immune imbalance and obesity in women with or without polycystic ovary syndrome

(2018) Ping Gong et al.   GYNECOLOGICAL ENDOCRINOLOGY

Multidimensional communication in the microenvirons of glioblastoma

(2018) Marike L. Broekman et al.   Nature Reviews Neurology

Gut microbiome–mediated bile acid metabolism regulates liver cancer via NKT cells

(2018) Chi Ma et al.   SCIENCE

Correlation between lower balance of Th2 helper T-cells and expression of PD-L1/PD-1 axis genes enables prognostic prediction in patients with glioblastoma

(2018) Yasuo Takashima et al.   Oncotarget

Gene therapy for human glioblastoma using neurotropic JC virus-like particles as a gene delivery vector

(2018) Chun-Nun Chao et al.   Scientific Reports

Survival gain in glioblastoma patients treated with dendritic cell immunotherapy is associated with increased NK but not CD8+ T cell activation in the presence of adjuvant temozolomide

(2018) Serena Pellegatta et al.   OncoImmunology

The immune checkpoint protein PD-L1 induces and maintains regulatory T cells in glioblastoma

(2018) Joseph DiDomenico et al.   OncoImmunology

Expression of LAG-3 and efficacy of combination treatment with anti-LAG-3 and anti-PD-1 monoclonal antibodies in glioblastoma

(2018) Sarah Harris-Bookman et al.   INTERNATIONAL JOURNAL OF CANCER

Identification of tumor antigens among the HLA peptidomes of Glioblastoma tumors and plasma

(2018) Bracha Shraibman et al.   MOLECULAR & CELLULAR PROTEOMICS

Indirubin ameliorates imiquimod-induced psoriasis-like skin lesions in mice by inhibiting inflammatory responses mediated by IL-17A-producing γδ T cells

(2018) Xiang-jiang Xie et al.   MOLECULAR IMMUNOLOGY

Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors

(2018) Pakawat Chongsathidkiet et al.   NATURE MEDICINE

Brain tumor-initiating cells export tenascin-C associated with exosomes to suppress T cell activity

(2018) Reza Mirzaei et al.   OncoImmunology

Checkpoint blockade reverses anergy in IL13Rα2 humanized scFv based CAR T cells to treat murine and canine gliomas.

(2018) Yibo Yin et al.   Molecular Therapy-Oncolytics

Immunomodulation Mediated by Anti-angiogenic Therapy Improves CD8 T Cell Immunity Against Experimental Glioma

(2018) Courtney S. Malo et al.   Frontiers in Oncology

Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor

(2018) Huimin Hu et al.   CELL

CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review

(2018) Bagher Farhood et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Local Application of Autologous Platelet-Rich Fibrin Patch (PRF-P) Suppresses Regulatory T Cell Recruitment in a Murine Glioma Model

(2018) Wojciech K. Panek et al.   MOLECULAR NEUROBIOLOGY

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

(2018) Derin B. Keskin et al.   NATURE

Viral and other therapies for recurrent glioblastoma: is a 24-month durable response unusual?

(2018) E Antonio Chiocca et al.   NEURO-ONCOLOGY

Immune Checkpoints and Innovative Therapies in Glioblastoma

(2018) Massimo Romani et al.   Frontiers in Oncology

Immunosuppressive Myeloid Cells’ Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy

(2017) Neha Kamran et al.   MOLECULAR THERAPY

T Helper Cell Differentiation, Heterogeneity, and Plasticity

(2017) Jinfang Zhu   Cold Spring Harbor Perspectives in Biology

Tumor-infiltrating γδT cells predict prognosis and adjuvant chemotherapeutic benefit in patients with gastric cancer

(2017) Jieti Wang et al.   OncoImmunology

Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme

(2017) Brittany A. Goods et al.   PLoS One

Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas

(2016) Jennifer E. Kim et al.   CLINICAL CANCER RESEARCH

CD4+Foxp3− type 1 regulatory T cells in glioblastoma multiforme suppress T cell responses through multiple pathways and are regulated by tumor-associated macrophages

(2016) Zhao Li et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Antitumor effects of minodronate, a third-generation nitrogen-containing bisphosphonate, in synergy with γδT cells in human glioblastoma in vitro and in vivo

(2016) Tsutomu Nakazawa et al.   JOURNAL OF NEURO-ONCOLOGY

Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival

(2016) Jonas Kloepper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Serum macrophage-derived chemokine/CCL22 levels are associated with glioma risk, CD4 T cell lymphopenia and survival time

(2015) Mi Zhou et al.   INTERNATIONAL JOURNAL OF CANCER

Myeloid derived suppressor cell infiltration of murine and human gliomas is associated with reduction of tumor infiltrating lymphocytes

(2015) Baisakhi Raychaudhuri et al.   JOURNAL OF NEURO-ONCOLOGY

Effective Treatment of Established GL261 Murine Gliomas through Picornavirus Vaccination-Enhanced Tumor Antigen-Specific CD8+ T Cell Responses

(2015) Danielle N. Renner et al.   PLoS One

GBM Derived Gangliosides Induce T Cell Apoptosis through Activation of the Caspase Cascade Involving Both the Extrinsic and the Intrinsic Pathway

(2015) Barun Mahata et al.   PLoS One

NKG2D- and T-cell receptor-dependent lysis of malignant glioma cell lines by human γδ T cells: Modulation by temozolomide and A disintegrin and metalloproteases 10 and 17 inhibitors

(2015) Guranda Chitadze et al.   OncoImmunology

Combination of Oncolytic Herpes Simplex Viruses Armed with Angiostatin and IL-12 Enhances Antitumor Efficacy in Human Glioblastoma Models

(2015) Wei Zhang et al.   NEOPLASIA

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Depleting tumor-specific Tregs at a single site eradicates disseminated tumors

(2013) Aurélien Marabelle et al.   JOURNAL OF CLINICAL INVESTIGATION

Cytotoxic human peripheral blood-derived γδT cells kill glioblastoma cell lines: implications for cell-based immunotherapy for patients with glioblastoma

(2013) Tsutomu Nakazawa et al.   JOURNAL OF NEURO-ONCOLOGY

Decreased expression of indoleamine 2,3-dioxygenase 1 in dendritic cells contributes to impaired regulatory T cell development in immune thrombocytopenia

(2012) Lucia Catani et al.   ANNALS OF HEMATOLOGY

Profound tumor-specific Th2 bias in patients with malignant glioma

(2012) Shinji Shimato et al.   BMC CANCER

Effector T-Cell Infiltration Positively Impacts Survival of Glioblastoma Patients and Is Impaired by Tumor-Derived TGF- 

(2011) J. Lohr et al.   CLINICAL CANCER RESEARCH

γδ T cells as immune effectors against high-grade gliomas

(2009) Lawrence S. Lamb   IMMUNOLOGIC RESEARCH

Characterization and immunotherapeutic potential of γδ T-cells in patients with glioblastoma

(2009) Nichole L. Bryant et al.   NEURO-ONCOLOGY

Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1

(2009) R. Ueda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA