Impaired circulating myeloid CD1c+ dendritic cell function in human glioblastoma is restored by p38 inhibition – implications for the next generation of DC vaccines

OS10.3 Randomized Phase 3 Study Evaluating the Efficacy and Safety of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: CheckMate 143

(2017) D. A. Reardon et al.   NEURO-ONCOLOGY

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Corticosteroids compromise survival in glioblastoma

(2016) Kenneth L. Pitter et al.   BRAIN

Tumor-derived factors modulating dendritic cell function

(2016) Jinbao Zong et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The Where, the When, and the How of Immune Monitoring for Cancer Immunotherapies in the Era of Checkpoint Inhibition

(2016) P. S. Hegde et al.   CLINICAL CANCER RESEARCH

Advances and challenges: dendritic cell vaccination strategies for glioblastoma

(2016) Teilo H. Schaller et al.   Expert Review of Vaccines

Impact of p38 mitogen-activated protein kinase inhibition on immunostimulatory properties of human 6-sulfo LacNAc dendritic cells

(2016) Saskia Langosch et al.   IMMUNOBIOLOGY

Tolerogenic Phenotype of IFN-γ–Induced IDO+Dendritic Cells Is Maintained via an Autocrine IDO–Kynurenine/AhR–IDO Loop

(2016) Qingsheng Li et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells and Cancer Immunity

(2016) Alycia Gardner et al.   TRENDS IN IMMUNOLOGY

Dexamethasone exerts profound immunologic interference on treatment efficacy for recurrent glioblastoma

(2015) E T Wong et al.   BRITISH JOURNAL OF CANCER

Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells

(2015) G. Schreibelt et al.   CLINICAL CANCER RESEARCH

Pooled Analysis of Long-Term Survival Data From Phase II and Phase III Trials of Ipilimumab in Unresectable or Metastatic Melanoma

(2015) Dirk Schadendorf et al.   JOURNAL OF CLINICAL ONCOLOGY

A Phase I Clinical Trial of CD1c (BDCA-1)+ Dendritic Cells Pulsed With HLA-A*0201 Peptides for Immunotherapy of Metastatic Hormone Refractory Prostate Cancer

(2015) Rebecca L. Prue et al.   JOURNAL OF IMMUNOTHERAPY

Cancer Immunotherapy with Immunomodulatory Anti-CD137 and Anti-PD-1 Monoclonal Antibodies Requires BATF3-Dependent Dendritic Cells

(2015) A. R. Sanchez-Paulete et al.   Cancer Discovery

Brain Tumor Immunotherapy: What have We Learned so Far?

(2015) Stefaan Willy Van Gool   Frontiers in Oncology

Leukopak PBMC sample processing for preparing quality control material to support proficiency testing programs

(2014) Ambrosia Garcia et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Clinical use of dendritic cells for cancer therapy

(2014) Sébastien Anguille et al.   LANCET ONCOLOGY

Immunotherapy advances for glioblastoma

(2014) D. A. Reardon et al.   NEURO-ONCOLOGY

Paradigm Shift in Dendritic Cell-Based Immunotherapy: From in vitro Generated Monocyte-Derived DCs to Naturally Circulating DC Subsets

(2014) Florian Wimmers et al.   Frontiers in Immunology

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

Src-kinase inhibitors sensitize human cells of myeloid origin to Toll-like-receptor-induced interleukin 12 synthesis

(2013) M. Wolfl et al.   BLOOD

Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses

(2013) G. Nizzoli et al.   BLOOD

Dendritic-Cell-Based Therapeutic Cancer Vaccines

(2013) Karolina Palucka et al.   IMMUNITY

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

Human dendritic cell subsets

(2013) Matthew Collin et al.   IMMUNOLOGY

Novel function for the p38-MK2 signaling pathway in circulating CD1c+ (BDCA-1+) myeloid dendritic cells from healthy donors and advanced cancer patients; inhibition of p38 enhances IL-12 whilst suppressing IL-10

(2013) Hester A. Franks et al.   INTERNATIONAL JOURNAL OF CANCER

Phenotypical analysis, relation to malignancy and prognostic relevance of ICOS+T regulatory and dendritic cells in patients with gliomas

(2013) Konstantinos Gousias et al.   JOURNAL OF NEUROIMMUNOLOGY

Efficacy and safety of the oral p38 inhibitor PH-797804 in chronic obstructive pulmonary disease: a randomised clinical trial

(2013) William MacNee et al.   THORAX

The Bidirectional Crosstalk between Human Dendritic Cells and Natural Killer Cells

(2011) Rebekka Wehner et al.   Journal of Innate Immunity

From IL-10 to IL-12: how pathogens and their products stimulate APCs to induce TH1 development

(2009) Anne O'Garra et al.   NATURE IMMUNOLOGY

Dexamethasone transforms lipopolysaccharide-stimulated human blood myeloid dendritic cells into myeloid dendritic cells that prime interleukin-10 production in T cells

(2008) Brenda M. Bosma et al.   IMMUNOLOGY

Tumour-mediated disruption of dendritic cell function: Inhibiting the MEK1/2-p44/42 axis restores IL-12 production and Th1-generation

(2008) Andrew Mark Jackson et al.   INTERNATIONAL JOURNAL OF CANCER

Reciprocal activating interaction between 6-sulfo LacNAc+dendritic cells and NK cells

(2008) Rebekka Wehner et al.   INTERNATIONAL JOURNAL OF CANCER