Pan-cancer analysis of NLRP3 inflammasome with potential implications in prognosis and immunotherapy in human cancer

Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation

(2020) Motao Zhu et al.   ACS Nano

The NLRP3 inflammasome: a therapeutic target for inflammation-associated cancers

(2020) Mahdi Gouravani et al.   Expert Review of Clinical Immunology

Top 10 Challenges in Cancer Immunotherapy

(2020) Priti S. Hegde et al.   IMMUNITY

Neoadjuvant checkpoint blockade for cancer immunotherapy

(2020) Suzanne L. Topalian et al.   SCIENCE

A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti–PD-1 immunotherapy

(2020) Balamayoora Theivanthiran et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential role of the NLRP3 inflammasome in infection and tumorigenesis

(2019) Sarang Tartey et al.   IMMUNOLOGY

Increased glycolysis correlates with elevated immune activity in tumor immune microenvironment

(2019) Zehang Jiang et al.   EBioMedicine

Biomarkers for Predicting Response to Immunotherapy with Immune Checkpoint Inhibitors in Cancer Patients

(2019) Michael J. Duffy et al.   CLINICAL CHEMISTRY

The Immune Landscape of Cancer

(2018) Vésteinn Thorsson et al.   IMMUNITY

Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma

(2018) Diana Miao et al.   SCIENCE

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

A Comprehensive Immunologic Portrait of Triple-Negative Breast Cancer

(2018) Zhixian Liu et al.   Translational Oncology

Integrative analysis of DNA methylation and gene expression reveals hepatocellular carcinoma-specific diagnostic biomarkers

(2018) Jinming Cheng et al.   Genome Medicine

Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic

(2018) T A Chan et al.   ANNALS OF ONCOLOGY

Role of the NLRP3 inflammasome in cancer

(2018) Maryam Moossavi et al.   Molecular Cancer

Eosinophilic count as a biomarker for prognosis of melanoma patients and its importance in the response to immunotherapy

(2017) Alvaro Moreira et al.   Immunotherapy

NLRP3 inflammasome activation promotes inflammation-induced carcinogenesis in head and neck squamous cell carcinoma

(2017) Cong-Fa Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma

(2017) Donnele Daley et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers

(2017) Aaron M. Goodman et al.   MOLECULAR CANCER THERAPEUTICS

Cancer cells induce interleukin-22 production from memory CD4+T cells via interleukin-1 to promote tumor growth

(2017) Cornelia Voigt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammasomes and Cancer

(2017) Rajendra Karki et al.   Cancer Immunology Research

Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy

(2016) D. B. Page et al.   Cancer Immunology Research

Genomic profiling of CHEK2*1100delC-mutated breast carcinomas

(2015) Maarten P. G. Massink et al.   BMC CANCER

The Nlrp3 Inflammasome Suppresses Colorectal Cancer Metastatic Growth in the Liver by Promoting Natural Killer Cell Tumoricidal Activity

(2015) Jeremy Dupaul-Chicoine et al.   IMMUNITY

Regulation of inflammasome activation

(2015) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

PD-L1 Expression as a Predictive Biomarker in Cancer Immunotherapy

(2015) S. P. Patel et al.   MOLECULAR CANCER THERAPEUTICS

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Deregulation of the NLRP3 inflammasome in hepatic parenchymal cells during liver cancer progression

(2013) Qing Wei et al.   LABORATORY INVESTIGATION

Inferring tumour purity and stromal and immune cell admixture from expression data

(2013) Kosuke Yoshihara et al.   Nature Communications

Genetic variation and alterations of genes involved in NFκB/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer

(2012) Jonas Ungerbäck et al.   CARCINOGENESIS

Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma

(2012) Lih-Chyang Chen et al.   EMBO Molecular Medicine

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

(2012) Mélanie Bruchard et al.   NATURE MEDICINE

Inflammasome polymorphisms confer susceptibility to sporadic malignant melanoma

(2012) Deepti Verma et al.   Pigment Cell & Melanoma Research

IL-18 Induces PD-1-Dependent Immunosuppression in Cancer

(2011) M. Terme et al.   CANCER RESEARCH

Tumor-Host Interactions: A Far-Reaching Relationship

(2010) Sandra S. McAllister et al.   JOURNAL OF CLINICAL ONCOLOGY

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

(2010) Irving C. Allen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β

(2009) Miyako Okamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY