NLRP3 inflammasome activation promotes inflammation-induced carcinogenesis in head and neck squamous cell carcinoma

Determinants of metastatic competency in colorectal cancer

(2017) Daniele V. F. Tauriello et al.   Molecular Oncology

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

B7-H4 expression indicates poor prognosis of oral squamous cell carcinoma

(2016) Lei Wu et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Inflammasome-independent NLRP3 is required for epithelial-mesenchymal transition in colon cancer cells

(2016) Hong Wang et al.   EXPERIMENTAL CELL RESEARCH

Activation of NLRP3 inflammasome enhances the proliferation and migration of A549 lung cancer cells

(2016) YANLI WANG et al.   ONCOLOGY REPORTS

ASC contributes to metastasis of oral cavity squamous cell carcinoma

(2016) Chi-Sheng Wu et al.   Oncotarget

Hypoxia primes human normal prostate epithelial cells and cancer cell lines for the NLRP3 and AIM2 inflammasome activation

(2016) Ravichandran Panchanathan et al.   Oncotarget

Hypoxia induces TFE3 expression in head and neck squamous cell carcinoma

(2016) Zhi-Jun Sun et al.   Oncotarget

CTLA4 blockade reduces immature myeloid cells in head and neck squamous cell carcinoma

(2016) Guang-Tao Yu et al.   OncoImmunology

LAG-3 confers poor prognosis and its blockade reshapes antitumor response in head and neck squamous cell carcinoma

(2016) Wei-Wei Deng et al.   OncoImmunology

NOTCH1 inhibition enhances the efficacy of conventional chemotherapeutic agents by targeting head neck cancer stem cell

(2016) Zhi-Li Zhao et al.   Scientific Reports

Pro-Inflammatory Cytokine IL-1β Up-Regulates CXC Chemokine Receptor 4 via Notch and ERK Signaling Pathways in Tongue Squamous Cell Carcinoma

(2015) Yi Sun et al.   PLoS One

Differential expression of inflammasomes in lung cancer cell lines and tissues

(2015) Hui Kong et al.   TUMOR BIOLOGY

Anterior gradient protein 2 expression in high grade head and neck squamous cell carcinoma correlated with cancer stem cell and epithelial mesenchymal transition

(2015) Si-Rui Ma et al.   Oncotarget

Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression

(2015) Altaf Mohammed et al.   Oncotarget

PD-1 blockade attenuates immunosuppressive myeloid cells due to inhibition of CD47/SIRPα axis in HPV negative head and neck squamous cell carcinoma

(2015) Guang-Tao Yu et al.   Oncotarget

STAT3 blockade enhances the efficacy of conventional chemotherapeutic agents by eradicating head neck stemloid cancer cell

(2015) Lin-Lin Bu et al.   Oncotarget

NLRP3 inflammasome and its inhibitors: a review

(2015) Bo-Zong Shao et al.   Frontiers in Pharmacology

IL-1β Promotes Malignant Transformation and Tumor Aggressiveness in Oral Cancer

(2014) Chia-Huei Lee et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ASC-associated inflammation promotes cecal tumorigenesis in aryl hydrocarbon receptor-deficient mice

(2013) Togo Ikuta et al.   CARCINOGENESIS

Deregulation of the NLRP3 inflammasome in hepatic parenchymal cells during liver cancer progression

(2013) Qing Wei et al.   LABORATORY INVESTIGATION

Chemopreventive and Chemotherapeutic Actions of mTOR Inhibitor in Genetically Defined Head and Neck Squamous Cell Carcinoma Mouse Model

(2012) Z.-J. Sun et al.   CLINICAL CANCER RESEARCH

IL-1β promotes stemness and invasiveness of colon cancer cells through Zeb1 activation

(2012) Yijing Li et al.   Molecular Cancer

Inflammasomes in carcinogenesis and anticancer immune responses

(2012) Laurence Zitvogel et al.   NATURE IMMUNOLOGY

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

(2012) Mélanie Bruchard et al.   NATURE MEDICINE

Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis

(2012) S. K. Drexler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Loss of TGF-β signaling and PTEN promotes head and neck squamous cell carcinoma through cellular senescence evasion and cancer-related inflammation

(2011) Y Bian et al.   ONCOGENE

Implications of understanding cancer stem cell (CSC) biology in head and neck squamous cell cancer

(2011) Suhail I. Sayed et al.   ORAL ONCOLOGY

Development and Maintenance of Cancer Stem Cells under Chronic Inflammation

(2011) Toshihiko Tanno et al.   JOURNAL OF NIPPON MEDICAL SCHOOL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

(2010) Irving C. Allen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-18 Production Downstream of the Nlrp3 Inflammasome Confers Protection against Colorectal Tumor Formation

(2010) M. H. Zaki et al.   JOURNAL OF IMMUNOLOGY

Epigenetic silencing of MAL, a putative tumor suppressor gene, can contribute to human epithelium cell carcinoma

(2010) Wei Cao et al.   Molecular Cancer

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β

(2009) Miyako Okamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: Necrosis Activates the NLRP3 Inflammasome

(2009) H. Li et al.   JOURNAL OF IMMUNOLOGY

Overexpression of Interleukin-1β Induces Gastric Inflammation and Cancer and Mobilizes Myeloid-Derived Suppressor Cells in Mice

(2008) Shuiping Tu et al.   CANCER CELL

Global epidemiology of oral and oropharyngeal cancer

(2008) Saman Warnakulasuriya   ORAL ONCOLOGY