Three-dimensional analysis of synaptic organization in the hippocampal CA1 field in Alzheimer’s disease

From the Entorhinal Region via the Prosubiculum to the Dentate Fascia: Alzheimer Disease-Related Neurofibrillary Changes in the Temporal Allocortex

(2020) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Three-dimensional synaptic organization of the human hippocampal CA1 field

(2020) Marta Montero-Crespo et al.   eLife

Subregional Density of Neurons, Neurofibrillary Tangles and Amyloid Plaques in the Hippocampus of Patients With Alzheimer’s Disease

(2019) Diana Furcila et al.   Frontiers in Neuroanatomy

Evidence for altered dendritic spine compartmentalization in Alzheimer’s disease and functional effects in a mouse model

(2018) Alexandre Androuin et al.   ACTA NEUROPATHOLOGICA

Synapse-to-nucleus communication: from developmental disorders to Alzheimer's disease

(2018) Elena Marcello et al.   CURRENT OPINION IN NEUROBIOLOGY

Our Tau Tales from Normal to Pathological Behavior

(2018) Alejandra D. Alonso et al.   JOURNAL OF ALZHEIMERS DISEASE

A Study of Amyloid-β and Phosphotau in Plaques and Neurons in the Hippocampus of Alzheimer’s Disease Patients

(2018) Diana Furcila et al.   JOURNAL OF ALZHEIMERS DISEASE

Synaptic dysfunction in Alzheimer's disease: the effects of amyloid beta on synaptic vesicle dynamics as a novel target for therapeutic intervention

(2018) Pavlos Alifragis et al.   Neural Regeneration Research

In vivo STED microscopy visualizes PSD95 sub-structures and morphological changes over several hours in the mouse visual cortex

(2018) Waja Wegner et al.   Scientific Reports

Three-dimensional analysis of synapses in the transentorhinal cortex of Alzheimer’s disease patients

(2018) M. Domínguez-Álvaro et al.   Acta Neuropathologica Communications

Synaptic Loss in the Inferior Temporal Gyrus in Mild Cognitive Impairment and Alzheimer's Disease

(2018) Stephen W. Scheff et al.   JOURNAL OF ALZHEIMERS DISEASE

Neurovascular Defects and Faulty Amyloid-β Vascular Clearance in Alzheimer's Disease

(2018) Abhay P. Sagare et al.   JOURNAL OF ALZHEIMERS DISEASE

FIB/SEM Technology and Alzheimer's Disease: Three-Dimensional Analysis of Human Cortical Synapses

(2018) Lidia Blazquez-Llorca et al.   JOURNAL OF ALZHEIMERS DISEASE

Synaptic Change in the Posterior Cingulate Gyrus in the Progression of Alzheimer's Disease

(2018) Stephen W. Scheff et al.   JOURNAL OF ALZHEIMERS DISEASE

Synaptic dysfunction in Alzheimer's disease: Mechanisms and therapeutic strategies

(2018) Yu Chen et al.   PHARMACOLOGY & THERAPEUTICS

Amyloid-Beta and Phosphorylated Tau Accumulations Cause Abnormalities at Synapses of Alzheimer’s disease Neurons

(2017) Ravi Rajmohan et al.   JOURNAL OF ALZHEIMERS DISEASE

Transcellular Nanoalignment of Synaptic Function

(2017) Thomas Biederer et al.   NEURON

Glutamatergic synapses are structurally and biochemically complex because of multiple plasticity processes: long-term potentiation, long-term depression, short-term potentiation and scaling

(2017) John Lisman   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Monoaminergic neuropathology in Alzheimer’s disease

(2017) Goran Šimić et al.   PROGRESS IN NEUROBIOLOGY

Synaptic Impairment in Alzheimer’s Disease: A Dysregulated Symphony

(2017) Stefania Forner et al.   TRENDS IN NEUROSCIENCES

Tau association with synaptic vesicles causes presynaptic dysfunction

(2017) Lujia Zhou et al.   Nature Communications

High plasticity of axonal pathology in Alzheimer’s disease mouse models

(2017) Lidia Blazquez-Llorca et al.   Acta Neuropathologica Communications

Neuropathologic Alterations in Mild Cognitive Impairment: A Review

(2017) William R. Markesbery   JOURNAL OF ALZHEIMERS DISEASE

Synaptic pathology: A shared mechanism in neurological disease

(2016) Christopher M. Henstridge et al.   AGEING RESEARCH REVIEWS

Neurovascular dysfunction and neurodegeneration in dementia and Alzheimer's disease

(2016) Amy R. Nelson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Potential mechanisms and implications for the formation of tau oligomeric strains

(2016) Julia E. Gerson et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Tau neurotoxicity and rescue in animal models of human Tauopathies

(2016) Lars Krüger et al.   CURRENT OPINION IN NEUROBIOLOGY

Opposing Effects of Neuronal Activity on Structural Plasticity

(2016) Michael Fauth et al.   Frontiers in Neuroanatomy

Analyzing dendritic spine pathology in Alzheimer’s disease: problems and opportunities

(2015) Mario M. Dorostkar et al.   ACTA NEUROPATHOLOGICA

Vascular contributions to cognitive impairment and dementia including Alzheimer's disease

(2015) Heather M. Snyder et al.   Alzheimers & Dementia

Cerebrospinal Fluid Biomarkers of Neurovascular Dysfunction in Mild Dementia and Alzheimer'S Disease

(2015) Melanie D Sweeney et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The dendritic spine story: an intriguing process of discovery

(2015) Javier DeFelipe   Frontiers in Neuroanatomy

FIB/SEM technology and high-throughput 3D reconstruction of dendritic spines and synapses in GFP-labeled adult-generated neurons

(2015) Carles Bosch et al.   Frontiers in Neuroanatomy

Vascular Plasticity and Cognition During Normal Aging and Dementia

(2015) Axel Montagne et al.   JAMA Neurology

Evidence for Alzheimer’s disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons

(2014) Krystina M. Neuman et al.   Brain Structure & Function

Spatial distribution of neurons innervated by chandelier cells

(2014) Lidia Blazquez-Llorca et al.   Brain Structure & Function

Recommendations of the Alzheimer's Disease-Related Dementias Conference

(2014) T. J. Montine et al.   NEUROLOGY

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

Three-dimensional distribution of cortical synapses: a replicated point pattern-based analysis

(2014) Laura Anton-Sanchez et al.   Frontiers in Neuroanatomy

The influence of phospho-tau on dendritic spines of cortical pyramidal neurons in patients with Alzheimer’s disease

(2013) Paula Merino-Serrais et al.   BRAIN

Cell number changes in Alzheimer's disease relate to dementia, not to plaques and tangles

(2013) C. H. Andrade-Moraes et al.   BRAIN

Three-Dimensional Spatial Distribution of Synapses in the Neocortex: A Dual-Beam Electron Microscopy Study

(2013) Angel Merchán-Pérez et al.   CEREBRAL CORTEX

Synaptic Changes in the Dentate Gyrus of APP/PS1 Transgenic Mice Revealed by Electron Microscopy

(2013) Lidia Alonso-Nanclares et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment

(2013) Scott E. Counts et al.   NEUROPHARMACOLOGY

Characterization and extraction of the synaptic apposition surface for synaptic geometry analysis

(2013) Juan Morales et al.   Frontiers in Neuroanatomy

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

(2012) Peter T. Nelson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Release probability of hippocampal glutamatergic terminals scales with the size of the active zone

(2012) Noemi Holderith et al.   NATURE NEUROSCIENCE

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

Defining Alzheimer as a common age-related neurodegenerative process not inevitably leading to dementia

(2012) Isidro Ferrer   PROGRESS IN NEUROBIOLOGY

Synapses and Dendritic Spines as Pathogenic Targets in Alzheimer’s Disease

(2012) Wendou Yu et al.   NEURAL PLASTICITY

Homeostatic responses by surviving cortical pyramidal cells in neurodegenerative tauopathy

(2011) Johanna L. Crimins et al.   ACTA NEUROPATHOLOGICA

Aβ Oligomer-Induced Synapse Degeneration in Alzheimer’s Disease

(2011) Kyle C. Wilcox et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Dendritic Spines: The Stuff That Memories Are Made Of?

(2010) Sonja B. Hofer et al.   CURRENT BIOLOGY

Layer-specific alterations to CA1 dendritic spines in a mouse model of Alzheimer's disease

(2010) P. Merino-Serrais et al.   HIPPOCAMPUS

From the Connectome to the Synaptome: An Epic Love Story

(2010) J. DeFelipe   SCIENCE

Microvasculature changes and cerebral amyloid angiopathy in Alzheimer’s disease and their potential impact on therapy

(2009) Roy O. Weller et al.   ACTA NEUROPATHOLOGICA

Synaptic degeneration in Alzheimer’s disease

(2009) Thomas Arendt   ACTA NEUROPATHOLOGICA

Input-Specific Intrasynaptic Arrangements of Ionotropic Glutamate Receptors and Their Impact on Postsynaptic Responses

(2009) E. Tarusawa et al.   JOURNAL OF NEUROSCIENCE

Morphological alterations to neurons of the amygdala and impaired fear conditioning in a transgenic mouse model of Alzheimer's disease

(2009) Shira Knafo et al.   JOURNAL OF PATHOLOGY

Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease

(2009) Joseph L. Price et al.   NEUROBIOLOGY OF AGING

The Episodic Memory System: Neurocircuitry and Disorders

(2009) Bradford C Dickerson et al.   NEUROPSYCHOPHARMACOLOGY

Diminished perisomatic GABAergic terminals on cortical neurons adjacent to amyloid plaques

(2009) Virginia Garcia-Marin   Frontiers in Neuroanatomy

Counting synapses using FIB/SEM microscopy: a true revolution for ultrastructural volume reconstruction

(2009) Angel Merchan-Pérez   Frontiers in Neuroanatomy

Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies

(2008) Robert Adalbert et al.   BRAIN

Widespread Changes in Dendritic Spines in a Model of Alzheimer's Disease

(2008) S. Knafo et al.   CEREBRAL CORTEX

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON

Gender differences in human cortical synaptic density

(2008) L. Alonso-Nanclares et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA