The role of cortisol in ischemic heart disease, ischemic stroke, type 2 diabetes, and cardiovascular disease risk factors: a bi-directional Mendelian randomization study

Association of genetically predicted testosterone with thromboembolism, heart failure, and myocardial infarction: mendelian randomisation study in UK Biobank

(2019) Shan Luo et al.   BMJ-British Medical Journal

An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

(2019) Tom G Richardson et al.   eLife

Morning plasma cortisol as a cardiovascular risk factor: findings from prospective cohort and Mendelian randomization studies

(2019) Andrew Alexander Crawford et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Genetic association study of eight steroid hormones and implications for sexual dimorphism of coronary artery disease

(2019) Janne Pott et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Evaluating the potential role of pleiotropy in Mendelian randomization studies

(2018) Gibran Hemani et al.   HUMAN MOLECULAR GENETICS

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

(2018) Rainer Malik et al.   NATURE GENETICS

Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians

(2018) Neil M Davies et al.   BMJ-British Medical Journal

Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians

(2018) Neil M Davies et al.   BMJ-British Medical Journal

OUP accepted manuscript

(2018)   AMERICAN JOURNAL OF EPIDEMIOLOGY

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

(2018) Loic Yengo et al.   HUMAN MOLECULAR GENETICS

Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

(2018) Sara L Pulit et al.   HUMAN MOLECULAR GENETICS

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

(2018) Wei Zhou et al.   NATURE GENETICS

Evaluation of the causal effects between subjective wellbeing and cardiometabolic health: mendelian randomisation study

(2018) Robyn E Wootton et al.   BMJ-British Medical Journal

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

(2018) Anubha Mahajan et al.   NATURE GENETICS

Visceral Fat and Novel Biomarkers of Cardiovascular Disease in Patients With Addison’s Disease: A Case-Control Study

(2017) Ragnhildur Bergthorsdottir et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites

(2017) Tao Long et al.   NATURE GENETICS

A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization

(2017) Jack Bowden et al.   STATISTICS IN MEDICINE

Comorbidities in the diseasome are more apparent than real: What Bayesian filtering reveals about the comorbidities of depression

(2017) Peter Marx et al.   PLoS Computational Biology

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

(2017) Eleanor Wheeler et al.   PLOS MEDICINE

Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease

(2017) Pim van der Harst et al.   CIRCULATION RESEARCH

PhenoScanner: a database of human genotype–phenotype associations

(2016) James R. Staley et al.   BIOINFORMATICS

Endogenous androgen exposures and ischemic heart disease, a separate sample Mendelian randomization study

(2016) Jie V. Zhao et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Assessing cortisol from hair samples in a large observational cohort: The Whitehall II study

(2016) Jessica G. Abell et al.   PSYCHONEUROENDOCRINOLOGY

LDlink: a web-based application for exploring population-specific haplotype structure and linking correlated alleles of possible functional variants: Fig. 1.

(2015) Mitchell J. Machiela et al.   BIOINFORMATICS

19 Testing causality in the association of plasma cortisol with risk of coronary heart disease: a mendelian randomisation study

(2015) AA Crawford et al.   HEART

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods

(2015) Stephen Burgess et al.   STATISTICS IN MEDICINE

An atlas of genetic influences on human blood metabolites

(2014) So-Youn Shin et al.   NATURE GENETICS

Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin

(2014) Jennifer L. Bolton et al.   PLoS Genetics

No physical health without mental health: lessons unlearned?

(2013) Kavitha Kolappa et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Calculating statistical power in Mendelian randomization studies

(2013) Marie-Jo A Brion et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Selection bias in cohorts of cases

(2013) C. Mary Schooling et al.   PREVENTIVE MEDICINE

Cushing's syndrome

(2013) J. K. Prague et al.   BMJ-British Medical Journal

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

(2012) Robert A Scott et al.   NATURE GENETICS

Risk of cardiovascular events in people prescribed glucocorticoids with iatrogenic Cushing's syndrome: cohort study

(2012) L. Fardet et al.   BMJ-British Medical Journal

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

(2011) Heribert Schunkert et al.   NATURE GENETICS

Increased urinary glucocorticoid metabolites are associated with metabolic syndrome, hypoadiponectinemia, insulin resistance and β cell dysfunction

(2011) Rene Baudrand et al.   STEROIDS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants

(2010) Brandon L Pierce et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Elevated Fasting Plasma Cortisol Is Associated with Ischemic Heart Disease and Its Risk Factors in People with Type 2 Diabetes: The Edinburgh Type 2 Diabetes Study

(2010) Rebecca M. Reynolds et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Psychological Stress and Cardiovascular Disease

(2008) Joel E. Dimsdale   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

(2007) Debbie A. Lawlor et al.   STATISTICS IN MEDICINE