Therapeutic promises of ginkgolide A: A literature-based review

ACE Inhibitors and ARBs in Patients with COVID-19

(2020) Grace I. Shyh et al.   Cardiology in Review

Role of Ginkgolides in the Inflammatory Immune Response of Neurological Diseases: A Review of Current Literatures

(2020) Chunrong Li et al.   Frontiers in Systems Neuroscience

Coronavirus 2019, Microthromboses, and Platelet Activating Factor

(2020) Theoharis C. Theoharides et al.   CLINICAL THERAPEUTICS

Regulation of platelet-activating factor-induced interleukin-8 expression by protein tyrosine phosphatase 1B

(2019) Geneviève Hamel-Côté et al.   Cell Communication and Signaling

Regulation of platelet-activating factor-mediated interleukin-6 promoter activation by the 48 kDa but not the 45 kDa isoform of protein tyrosine phosphatase non-receptor type 2

(2019) Geneviève Hamel-Côté et al.   Cell and Bioscience

Pregnane X receptor activation by its natural ligand Ginkgolide-A improves tight junction proteins expression and attenuates bacterial translocation in cirrhosis

(2019) Sundhar Mohandas et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The pharmacokinetics study of ginkgolide A, B and the effect of food on bioavailability after oral administration of ginkgolide extracts in beagle dogs

(2018) Lixiang Aa et al.   BIOMEDICAL CHROMATOGRAPHY

Blockade of platelet-activating factor receptor attenuates abnormal behaviors induced by phencyclidine in mice through down-regulation of NF-κB

(2018) The-Vinh Tran et al.   BRAIN RESEARCH BULLETIN

Amyloid-β Induces AMPA Receptor Ubiquitination and Degradation in Primary Neurons and Human Brains of Alzheimer’s Disease

(2018) Yanmin Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Okadaic acid–induced tau hyperphosphorylation and the downregulation of Pin1 expression in primary cortical neurons

(2018) Derya Metin-Armağan et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Alzheimer’s disease hypothesis and related therapies

(2018) Xiaoguang Du et al.   Translational Neurodegeneration

Human pharmacokinetics of ginkgo terpene lactones and impact of carboxylation in blood on their platelet-activating factor antagonistic activity

(2018) Xin-wei Liu et al.   ACTA PHARMACOLOGICA SINICA

Chemical analysis, pharmacological activity and process optimization of the proportion of bilobalide and ginkgolides in Ginkgo biloba extract

(2018) Lu Xiaoyan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Ginkgolide A Prevents the Amyloid-β-Induced Depolarization of Cortical Neurons

(2018) Li-Chen Kuo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Inflammatory responses and inflammation-associated diseases in organs

(2017) Linlin Chen et al.   Oncotarget

PXR Mediated Protection against Liver Inflammation by Ginkgolide A in Tetrachloromethane Treated Mice

(2016) Nanhui Ye et al.   Biomolecules & Therapeutics

The inflammatory response triggered by Influenza virus: a two edged sword

(2016) Luciana P. Tavares et al.   INFLAMMATION RESEARCH

Characterizations of the hydrolyzed products of ginkgolide A and ginkgolide B by liquid chromatography coupled with mass spectrometry

(2016) Ke Lan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Getting to NO Alzheimer’s Disease: Neuroprotection versus Neurotoxicity Mediated by Nitric Oxide

(2016) Rachelle Balez et al.   Oxidative Medicine and Cellular Longevity

ACE inhibition, ACE2 and angiotensin-(1⿿7) axis in kidney and cardiac inflammation and fibrosis

(2016) Ana Cristina Simões e Silva et al.   PHARMACOLOGICAL RESEARCH

Semi-quantitative determination of monocarboxylate forms of ginkgolide B in plasma by UPLC-MS

(2015) Xue-Jing Li et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Ginkgolide A reduces inflammatory response in high-glucose-stimulated human umbilical vein endothelial cells through STAT3-mediated pathway

(2015) Qiuping Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Accurate analysis of ginkgolides and their hydrolyzed metabolites by analytical supercritical fluid chromatography hybrid tandem mass spectrometry

(2015) Xin-Guang Liu et al.   JOURNAL OF CHROMATOGRAPHY A

Cross matching observations on toxicological and clinical data for the assessment of tolerability and safety of Ginkgo biloba leaf extract

(2015) Tuula Heinonen et al.   TOXICOLOGY

Ginkgo biloba extract (Egb761) attenuates zinc-induced tau phosphorylation at Ser262 by regulating GSK3β activity in rat primary cortical neurons

(2015) Kyoung Ja Kwon et al.   Food & Function

Anti-platelet effect of ginkgolide a from Ginkgo biloba

(2014) Jin-Hyeob Ryu et al.   Journal of the Korean Society for Applied Biological Chemistry

Roles of Bone-Marrow-Derived Cells and Inflammatory Cytokines in Neointimal Hyperplasia after Vascular Injury

(2014) Makoto Shoji et al.   Biomed Research International

Ginkgo biloba Extracts: A Review of the Pharmacokinetics of the Active Ingredients

(2013) Christian Ude et al.   CLINICAL PHARMACOKINETICS

The pharmacokinetics and conversion of the lactone to the carboxylate forms of ginkgolide B in rat plasma

(2013) Dian-Lei Wang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Neuroprotection against permanent focal cerebral ischemia by ginkgolides A and B is associated with obstruction of the mitochondrial apoptotic pathway via inhibition of c-Jun N-terminal kinase in rats

(2013) Xuan Wang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Two new nonacosanetriols from Ginkgo biloba sarcotesta

(2012) Guisheng Zhou et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Effects of Ginkgolide A on Okadaic Acid-induced Tau Hyperphosphorylation and the PI3K-Akt Signaling Pathway in N2a Cells

(2012) Yan Chen et al.   PLANTA MEDICA

PI3K-PKB/Akt Pathway

(2012) B. A. Hemmings et al.   Cold Spring Harbor Perspectives in Biology

Actions of β-Amyloid Protein on Human Neurons Are Expressed through the Amylin Receptor

(2011) Jack H. Jhamandas et al.   AMERICAN JOURNAL OF PATHOLOGY

Amyloid β peptide oligomers directly activate NMDA receptors

(2011) Laura Texidó et al.   CELL CALCIUM

Ginkgolide A-Gold Nanoparticles Inhibit Vascular Smooth Muscle Proliferation and Migration In Vitro and Reduce Neointimal Hyperplasia in a Mouse Model

(2011) Sarah M. Weakley et al.   JOURNAL OF SURGICAL RESEARCH

Human Pregnane X Receptor Agonism by Ginkgo biloba Extract: Assessment of the Role of Individual Ginkgolides

(2010) A. J. Lau et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics