Human pharmacokinetics of ginkgo terpene lactones and impact of carboxylation in blood on their platelet-activating factor antagonistic activity

Characterizations of the hydrolyzed products of ginkgolide A and ginkgolide B by liquid chromatography coupled with mass spectrometry

(2016) Ke Lan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Semi-quantitative determination of monocarboxylate forms of ginkgolide B in plasma by UPLC-MS

(2015) Xue-Jing Li et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Ginkgolide A reduces inflammatory response in high-glucose-stimulated human umbilical vein endothelial cells through STAT3-mediated pathway

(2015) Qiuping Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Accurate analysis of ginkgolides and their hydrolyzed metabolites by analytical supercritical fluid chromatography hybrid tandem mass spectrometry

(2015) Xin-Guang Liu et al.   JOURNAL OF CHROMATOGRAPHY A

Bilobalide attenuates hypoxia induced oxidative stress, inflammation, and mitochondrial dysfunctions in 3T3-L1 adipocytes via its antioxidant potential

(2014) A. Priyanka et al.   FREE RADICAL RESEARCH

Systemic and cerebral exposure to and pharmacokinetics of flavonols and terpene lactones after dosing standardizedGinkgo bilobaleaf extracts to rats via different routes of administration

(2013) Feng Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Ginkgo biloba Extracts: A Review of the Pharmacokinetics of the Active Ingredients

(2013) Christian Ude et al.   CLINICAL PHARMACOKINETICS

Anti-inflammatory effects of rutin on HMGB1-induced inflammatory responses in vitro and in vivo

(2013) Hayoung Yoo et al.   INFLAMMATION RESEARCH

The pharmacokinetics and conversion of the lactone to the carboxylate forms of ginkgolide B in rat plasma

(2013) Dian-Lei Wang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Hydrolysis Is the Dominating In Vivo Metabolism Pathway for Arctigenin: Identification of Novel Metabolites of Arctigenin by LC/MS/MS after Oral Administration in Rats

(2013) Qiong Gao et al.   PLANTA MEDICA

Intestinal Absorption and Presystemic Elimination of Various Chemical Constituents Present in GBE50 Extract, a Standardized Extract of Ginkgo biloba Leaves

(2012) Li Li et al.   CURRENT DRUG METABOLISM

Inhibition of NF-κB activation is associated with anti-inflammatory and anti-apoptotic effects of Ginkgolide B in a mouse model of cerebral ischemia/reperfusion injury

(2012) Jin-Hua Gu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Anti-ischaemic effects of bilobalide on neonatal rat cardiomyocytes and the involvement of the platelet-activating factor receptor

(2011) Stefanie Maerz et al.   BIOSCIENCE REPORTS

Human Paraoxonase 1 Is the Enzyme Responsible for Pilocarpine Hydrolysis

(2011) T. Hioki et al.   DRUG METABOLISM AND DISPOSITION

Ginkgolide B Reduces Inflammatory Protein Expression in Oxidized Low-density Lipoprotein-stimulated Human Vascular Endothelial Cells

(2011) Shan Zhang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Renal clearance in drug discovery and development: molecular descriptors, drug transporters and disease state

(2010) Bo Feng et al.   Expert Opinion on Drug Metabolism & Toxicology

Prediction of Biliary Excretion in Rats and Humans Using Molecular Weight and Quantitative Structure–Pharmacokinetic Relationships

(2009) Xinning Yang et al.   AAPS Journal

Blockade of Oxidized LDL-Triggered Endothelial Apoptosis by Quercetin and Rutin through Differential Signaling Pathways Involving JAK2

(2009) Jung-Suk Choi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Chemical analysis and quality control of Ginkgo biloba leaves, extracts, and phytopharmaceuticals

(2009) Teris A. van Beek et al.   JOURNAL OF CHROMATOGRAPHY A

Physicochemical Determinants of Human Renal Clearance

(2009) Manthena V. S. Varma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pharmacokinetics of bilobalide, ginkgolide A and B after administration of three differentGinkgo bilobaL. preparations in humans

(2009) Karin Woelkart et al.   PHYTOTHERAPY RESEARCH

The gastrointestinal microbiota as a site for the biotransformation of drugs

(2008) Tiago Sousa et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Transport characteristics of ginkgolide B by Caco-2 cells and examination of ginkgolide B oral absorption potential using rat in situ intestinal loop method

(2007) H LV et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Simultaneous determination of ginkgo flavonoids and terpenoids in plasma: Ammonium formate in LC mobile phase enhancing electrospray ionization efficiency and capacity

(2007) Yang Zhao et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY