Amyloid-β Induces AMPA Receptor Ubiquitination and Degradation in Primary Neurons and Human Brains of Alzheimer’s Disease

Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors

(2017) Jiuhe Zhu et al.   PLoS Genetics

Erratum to: β-Amyloid triggers aberrant over-scaling of homeostatic synaptic plasticity

(2017) James Gilbert et al.   Acta Neuropathologica Communications

Amyloid-β Decreases Cell-Surface AMPA Receptors by Increasing Intracellular Calcium and Phosphorylation of GluR2

(2017) Shi-Jie Liu et al.   JOURNAL OF ALZHEIMERS DISEASE

Learning, memory and long-term potentiation are altered in Nedd4 heterozygous mice

(2016) Daria Camera et al.   BEHAVIOURAL BRAIN RESEARCH

Aβ-Induced Synaptic Alterations Require the E3 Ubiquitin Ligase Nedd4-1

(2016) Elizabeth M. Rodrigues et al.   JOURNAL OF NEUROSCIENCE

Histone Modification of Nedd4 Ubiquitin Ligase Controls the Loss of AMPA Receptors and Cognitive Impairment Induced by Repeated Stress

(2016) J. Wei et al.   JOURNAL OF NEUROSCIENCE

Loss of NEDD4 contributes to RTP801 elevation and neuron toxicity: implications for Parkinson’s disease

(2016) Mercè Canal et al.   Oncotarget

Amyloid-β-Induced Dysregulation of AMPA Receptor Trafficking

(2016) Sumasri Guntupalli et al.   NEURAL PLASTICITY

Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity

(2015) Takashi Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The deubiquitinating enzyme USP46 regulates AMPA receptor ubiquitination and trafficking

(2015) Yuda Huo et al.   JOURNAL OF NEUROCHEMISTRY

USP46: a new piece of the memory puzzle?

(2015) Felipe C. Ribeiro et al.   JOURNAL OF NEUROCHEMISTRY

Endocytic Adaptor Epidermal Growth Factor Receptor Substrate 15 (Eps15) Is Involved in the Trafficking of Ubiquitinated α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptors

(2014) Amy Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The WD40-repeat Proteins WDR-20 and WDR-48 Bind and Activate the Deubiquitinating Enzyme USP-46 to Promote the Abundance of the Glutamate Receptor GLR-1 in the Ventral Nerve Cord ofCaenorhabditis elegans

(2013) Caroline L. Dahlberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parasynaptic NMDA Receptor Signaling Couples Neuronal Glutamate Transporter Function to AMPA Receptor Synaptic Distribution and Stability

(2012) L. A. Jarzylo et al.   JOURNAL OF NEUROSCIENCE

Upregulation of the E3 ligase NEDD4-1 by Oxidative Stress Degrades IGF-1 Receptor Protein in Neurodegeneration

(2012) Y.-D. Kwak et al.   JOURNAL OF NEUROSCIENCE

Inhibition of AMPA receptor trafficking at hippocampal synapses by β-amyloid oligomers: the mitochondrial contribution

(2012) Yanfang Rui et al.   Molecular Brain

AMPA Receptor Trafficking in Homeostatic Synaptic Plasticity: Functional Molecules and Signaling Cascades

(2012) Guan Wang et al.   NEURAL PLASTICITY

Soluble Oligomers of Amyloid-β Peptide Disrupt Membrane Trafficking of α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor Contributing to Early Synapse Dysfunction

(2011) Alfredo J. Miñano-Molina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduced levels of the tyrosine phosphatase STEP block beta amyloid-mediated GluA1/GluA2 receptor internalization

(2011) Yongfang Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Nedd4-mediated AMPA receptor ubiquitination regulates receptor turnover and trafficking

(2011) Amy Lin et al.   JOURNAL OF NEUROCHEMISTRY

Homeostatic Regulation of AMPA Receptor Trafficking and Degradation by Light-Controlled Single-Synaptic Activation

(2011) Qingming Hou et al.   NEURON

Activity-Dependent Ubiquitination of GluA1 Mediates a Distinct AMPA Receptor Endocytosis and Sorting Pathway

(2010) L. A. Schwarz et al.   JOURNAL OF NEUROSCIENCE

Eps15: a multifunctional adaptor protein regulating intracellular trafficking

(2009) Paul MP van Bergen en Henegouwen   Cell Communication and Signaling

β-Amyloid Impairs AMPA Receptor Trafficking and Function by Reducing Ca2+/Calmodulin-dependent Protein Kinase II Synaptic Distribution

(2009) Zhenglin Gu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Na,K-ATPase Activity Regulates AMPA Receptor Turnover through Proteasome-Mediated Proteolysis

(2009) D. Zhang et al.   JOURNAL OF NEUROSCIENCE

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

(2008) Dennis J. Selkoe   BEHAVIOURAL BRAIN RESEARCH

Homeostatic regulation of AMPA receptor expression at single hippocampal synapses

(2008) Q. Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA