Tyrosine-phosphorylation and activation of glucosylceramide synthase by v-Src: Its role in survival of HeLa cells against ceramide

Regulation of glucosylceramide synthesis by Golgi-localized phosphoinositide

(2018) Yohei Ishibashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1)

(2018) Marthe-Susanna Wegner et al.   BMC CANCER

UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells

(2018) Marthe-Susanna Wegner et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

v-Src-driven transformation is due to chromosome abnormalities but not Src-mediated growth signaling

(2018) Takuya Honda et al.   Scientific Reports

Complex formation of sphingomyelin synthase 1 with glucosylceramide synthase increases sphingomyelin and decreases glucosylceramide levels

(2018) Yasuhiro Hayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Translocation and activation of sphingosine kinase 1 by ceramide-1-phosphate

(2018) Shohei Nishino et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Phosphorylation and inhibition of ceramide kinase by protein kinase C-β: Their changes by serine residue mutations

(2018) Hiromasa Takahashi et al.   CELLULAR SIGNALLING

Involvement of Src signaling in the synergistic effect between cisplatin and digoxin on cancer cell viability

(2017) Duane G. Pereira et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Src Regulates Cigarette Smoke–Induced Ceramide Generation via Neutral Sphingomyelinase 2 in the Airway Epithelium

(2015) Samuel Chung et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Tamoxifen regulation of sphingolipid metabolism—Therapeutic implications

(2015) Samy A.F. Morad et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

AMP-activated Protein Kinase Suppresses Biosynthesis of Glucosylceramide by Reducing Intracellular Sugar Nucleotides

(2015) Yohei Ishibashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of alkaline ceramidase activity by the c-Src-mediated pathway

(2014) Hirotsune Sasaki et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

c-Fos: An AP-1 transcription factor with an additional cytoplasmic, non-genomic lipid synthesis activation capacity

(2014) Beatriz L. Caputto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Src signaling pathways in prostate cancer

(2014) Andreas Varkaris et al.   CANCER AND METASTASIS REVIEWS

Resistance to the antiproliferative effect induced by a short-chain ceramide is associated with an increase of glucosylceramide synthase, P-glycoprotein, and multidrug-resistance gene-1 in cervical cancer cells

(2014) Gisela Gutiérrez-Iglesias et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The development and use of small molecule inhibitors of glycosphingolipid metabolism for lysosomal storage diseases

(2014) James A. Shayman et al.   JOURNAL OF LIPID RESEARCH

Establishment of HeLa Cell Mutants Deficient in Sphingolipid-Related Genes Using TALENs

(2014) Toshiyuki Yamaji et al.   PLoS One

c-Src-induced activation of ceramide metabolism impairs membrane microdomains and promotes malignant progression by facilitating the translocation of c-Src to focal adhesions

(2013) Kentaro Kajiwara et al.   BIOCHEMICAL JOURNAL

New insights on glucosylated lipids: Metabolism and functions

(2013) Yohei Ishibashi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

v-Src causes delocalization of Mklp1, Aurora B, and INCENP from the spindle midzone during cytokinesis failure

(2013) Shuhei Soeda et al.   EXPERIMENTAL CELL RESEARCH

By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells

(2013) Masanobu Tsubaki et al.   LEUKEMIA RESEARCH

Doxorubicin Influences the Expression of Glucosylceramide Synthase in Invasive Ductal Breast Cancer

(2012) Xiaofang Zhang et al.   PLoS One

Up-regulation of ceramide glucosyltransferase during the differentiation of U937 cells

(2011) J. Aida et al.   JOURNAL OF BIOCHEMISTRY

Up-regulation of AMP-activated Protein Kinase in Cancer Cell Lines Is Mediated through c-Src Activation

(2011) Sarit Mizrachy-Schwartz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genistein Stimulates MCF-7 Breast Cancer Cell Growth by Inducing Acid Ceramidase (ASAH1) Gene Expression

(2011) Natasha C. Lucki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MDR1 (multidrug resistence 1) can regulate GCS (glucosylceramide synthase) in breast cancer cells

(2011) Xiaofang Zhang et al.   JOURNAL OF SURGICAL ONCOLOGY

ABCB1 Protects Kidney Proximal Tubule Cells Against Cadmium-Induced Apoptosis: Roles of Cadmium and Ceramide Transport

(2011) Wing-Kee Lee et al.   TOXICOLOGICAL SCIENCES

Activation of Ceramidase and Ceramide Kinase by Vanadate via a Tyrosine Kinase–Mediated Pathway

(2010) Eiko Tada et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Acute activation of acid ceramidase affects cytokine-induced cytotoxicity in rat islet β-cells

(2009) Qun Zhu et al.   FEBS LETTERS

Activation of Cytosolic Phospholipase A2α by Epidermal Growth Factor (EGF) and Phorbol Ester in HeLa Cells: Different Effects of Inhibitors for EGF Receptor, Protein Kinase C, Src, and C-Raf

(2009) Yasuo Matsuzawa et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Src kinases as therapeutic targets for cancer

(2009) Lori C. Kim et al.   Nature Reviews Clinical Oncology

A role for ceramide in driving cancer cell resistance to doxorubicin

(2008) Yong-Yu Liu et al.   FASEB JOURNAL

c-Fos Activates Glucosylceramide Synthase and Glycolipid Synthesis in PC12 Cells

(2008) Pilar M. Crespo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin-associated Lyn Kinase Promotes Cell Survival by Suppressing Acid Sphingomyelinase Activity

(2008) Daria A. Chudakova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization: alteration of AU-rich element-binding proteins

(2008) S Sobue et al.   ONCOGENE

EGF regulates plasminogen activator inhibitor-1 (PAI-1) by a pathway involving c-Src, PKCδ, and sphingosine kinase 1 in glioblastoma cells

(2007) Barbara S. Paugh et al.   FASEB JOURNAL