Selective autophagy: the rise of the zebrafish model

Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency

(2020) Alessandro Luciani et al.   Nature Communications

The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils

(2020) Tomasz K. Prajsnar et al.   Autophagy

Chaperone-Mediated Autophagy in the light of evolution: insight from fish

(2020) Laury Lescat et al.   MOLECULAR BIOLOGY AND EVOLUTION

Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages

(2020) Rui Zhang et al.   Cell Death & Disease

Neutrophils use selective autophagy receptor Sqstm1/p62 to target Staphylococcus aureus for degradation in vivo in zebrafish

(2020) Josie F. Gibson et al.   Autophagy

Atg8-Family Proteins—Structural Features and Molecular Interactions in Autophagy and Beyond

(2020) Nicole Wesch et al.   Cells

The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection

(2019) Rui Zhang et al.   PLoS Pathogens

The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria

(2019) Benjamin J. Ravenhill et al.   MOLECULAR CELL

Loss of the sphingolipid desaturase DEGS1 causes hypomyelinating leukodystrophy

(2019) Devesh C. Pant et al.   JOURNAL OF CLINICAL INVESTIGATION

A novel transgenic zebrafish line allows for in vivo quantification of autophagic activity in neurons

(2019) Sataree Khuansuwan et al.   Autophagy

Exploration of age-related mitochondrial dysfunction and the anti-aging effects of resveratrol in zebrafish retina

(2019) Ning Wang et al.   Aging-US

Watch What You (Self-) Eat: Autophagic Mechanisms that Modulate Metabolism

(2019) Vikramjit Lahiri et al.   Cell Metabolism

NIPSNAP1 and NIPSNAP2 Act as “Eat Me” Signals for Mitophagy

(2019) Yakubu Princely Abudu et al.   DEVELOPMENTAL CELL

History of The Selective Autophagy Research: How Did It Begin and Where Does It Stand Today?

(2019) Vladimir Kirkin   JOURNAL OF MOLECULAR BIOLOGY

Genetic compensation triggered by mutant mRNA degradation

(2019) Mohamed A. El-Brolosy et al.   NATURE

Reversible induction of mitophagy by an optogenetic bimodular system

(2019) Pasquale D’Acunzo et al.   Nature Communications

The LipoGlo reporter system for sensitive and specific monitoring of atherogenic lipoproteins

(2019) James H. Thierer et al.   Nature Communications

Inhibited Lipophagy Suppresses Lipid Metabolism in Zebrafish Liver Cells

(2019) Jing Wang et al.   Frontiers in Physiology

A Diversity of Selective Autophagy Receptors Determines the Specificity of the Autophagy Pathway

(2019) Vladimir Kirkin et al.   MOLECULAR CELL

A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish

(2018) Roland S. Wu et al.   DEVELOPMENTAL CELL

Zebrafish Infection: From Pathogenesis to Cell Biology

(2018) Vincenzo Torraca et al.   TRENDS IN CELL BIOLOGY

Lipophagy is essential for lipid metabolism in fish

(2018) Jing Wang et al.   Science Bulletin

Seeing is believing: methods to monitor vertebrate autophagy in vivo

(2018) Ana Lopez et al.   Open Biology

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

(2017) Myungjin Jo et al.   GENOME RESEARCH

Mitophagy in maintaining skeletal muscle mitochondrial proteostasis and metabolic health with ageing

(2017) Joshua C. Drake et al.   JOURNAL OF PHYSIOLOGY-LONDON

The pharmacological regulation of cellular mitophagy

(2017) Nikolaos D Georgakopoulos et al.   Nature Chemical Biology

ErbB2 regulates autophagic flux to modulate the proteostasis of APP-CTFs in Alzheimer’s disease

(2017) Bo-Jeng Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation

(2017) Jennifer Mesureur et al.   PLoS Pathogens

Lipid Uptake, Metabolism, and Transport in the Larval Zebrafish

(2017) Vanessa H. Quinlivan et al.   Frontiers in Endocrinology

Studying Autophagy in Zebrafish

(2017) Benan Mathai et al.   Cells

Autolysosome biogenesis and developmental senescence are regulated by both Spns1 and v-ATPase

(2016) Tomoyuki Sasaki et al.   Autophagy

Injections of Predatory Bacteria Work Alongside Host Immune Cells to Treat Shigella Infection in Zebrafish Larvae

(2016) Alexandra R. Willis et al.   CURRENT BIOLOGY

Salmonella plasmid virulence gene spvB enhances bacterial virulence by inhibiting autophagy in a zebrafish infection model

(2016) Yuan-yuan Li et al.   FISH & SHELLFISH IMMUNOLOGY

Drug Discovery in Fish, Flies, and Worms

(2016) Kevin Strange   ILAR JOURNAL

Inactivation of 3-hydroxybutyrate dehydrogenase2 delays zebrafish erythroid maturation by conferring premature mitophagy

(2016) Gangarao Davuluri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophils mediate Salmonella Typhimurium clearance through the GBP4 inflammasome-dependent production of prostaglandins

(2016) Sylwia D. Tyrkalska et al.   Nature Communications

Zebrafish Embryonic Lipidomic Analysis Reveals that the Yolk Cell Is Metabolically Active in Processing Lipid

(2016) Daniel Fraher et al.   Cell Reports

Expanding Roles for Lipid Droplets

(2015) Michael A. Welte   CURRENT BIOLOGY

The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

(2015) Alicia M. Pickrell et al.   NEURON

AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1

(2014) F Strappazzon et al.   CELL DEATH AND DIFFERENTIATION

The DNA Damage-Regulated Autophagy Modulator DRAM1 Links Mycobacterial Recognition via TLR-MYD88 to Autophagic Defense

(2014) Michiel van der Vaart et al.   Cell Host & Microbe

Zebrafish yolk lipid processing: a tractable tool for the study of vertebrate lipid transport and metabolism

(2014) R. L. Miyares et al.   Disease Models & Mechanisms

Fit for consumption: zebrafish as a model for tuberculosis

(2014) M. R. Cronan et al.   Disease Models & Mechanisms

Sqstm1 knock-down causes a locomotor phenotype ameliorated by rapamycin in a zebrafish model of ALS/FTLD

(2014) Serena Lattante et al.   HUMAN MOLECULAR GENETICS

Zebrafish ambra1a and ambra1b Knockdown Impairs Skeletal Muscle Development

(2014) Tatjana Skobo et al.   PLoS One

Loss of Optineurin In Vivo Results in Elevated Cell Death and Alters Axonal Trafficking Dynamics

(2014) Jeremiah D. Paulus et al.   PLoS One

Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation

(2014) A. Bernut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PICALM modulates autophagy activity and tau accumulation

(2014) Kevin Moreau et al.   Nature Communications

Zebrafish as a Natural Host Model for Vibrio cholerae Colonization and Transmission

(2013) Donna L. Runft et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Mitophagy and neurodegeneration

(2013) Kim Wager et al.   Autophagy

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Emerging regulation and functions of autophagy

(2013) Patricia Boya et al.   NATURE CELL BIOLOGY

The Zebrafish as a New Model for the In Vivo Study of Shigella flexneri Interaction with Phagocytes and Bacterial Autophagy

(2013) Serge Mostowy et al.   PLoS Pathogens

Infection-Responsive Expansion of the Hematopoietic Stem and Progenitor Cell Compartment in Zebrafish Is Dependent upon Inducible Nitric Oxide

(2012) Christopher J. Hall et al.   Cell Stem Cell

A privileged intraphagocyte niche is responsible for disseminated infection ofStaphylococcus aureusin a zebrafish model

(2012) Tomasz K. Prajsnar et al.   CELLULAR MICROBIOLOGY

Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates

(2012) J. Korac et al.   JOURNAL OF CELL SCIENCE

Mitophagy and Parkinson's disease: Be eaten to stay healthy

(2012) Rosa L.A. de Vries et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane

(2011) Saori R. Yoshii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish

(2011) Longhou Fang et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy machinery mediates macroendocytic processing and entotic cell death by targeting single membranes

(2011) Oliver Florey et al.   NATURE CELL BIOLOGY

Mitophagy and Parkinson's disease: The PINK1–parkin link

(2010) Emma Deas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Mammalian Siderophore Synthesized by an Enzyme with a Bacterial Homolog Involved in Enterobactin Production

(2010) Laxminarayana R. Devireddy et al.   CELL

Burkholderia cenocepacia Creates an Intramacrophage Replication Niche in Zebrafish Embryos, Followed by Bacterial Dissemination and Establishment of Systemic Infection

(2010) A. C. Vergunst et al.   INFECTION AND IMMUNITY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos

(2009) Congcong He et al.   Autophagy

Transposon-mediated BAC transgenesis in zebrafish and mice

(2009) Maximiliano L Suster et al.   BMC GENOMICS

Pseudomonas aeruginosaType III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryos

(2009) Mark K. Brannon et al.   CELLULAR MICROBIOLOGY

Vascular Lipid Accumulation, Lipoprotein Oxidation, and Macrophage Lipid Uptake in Hypercholesterolemic Zebrafish

(2009) Konstantin Stoletov et al.   CIRCULATION RESEARCH

Real-Time Observation of Listeria monocytogenes-Phagocyte Interactions in Living Zebrafish Larvae

(2009) J.-P. Levraud et al.   INFECTION AND IMMUNITY

Pseudomonas aeruginosa Infection of Zebrafish Involves both Host and Pathogen Determinants

(2009) A. E. Clatworthy et al.   INFECTION AND IMMUNITY

A novel vertebrate model ofStaphylococcus aureusinfection reveals phagocyte-dependent resistance of zebrafish to non-host specialized pathogens

(2008) Tomasz K. Prajsnar et al.   CELLULAR MICROBIOLOGY

Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish

(2008) K. Asakawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA