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Title
Pharmacological effects of harmine and its derivatives: a review
Authors
Keywords
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Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 43, Issue 12, Pages 1259-1275
Publisher
Springer Science and Business Media LLC
Online
2020-11-18
DOI
10.1007/s12272-020-01283-6
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Note: Only part of the references are listed.- Synthesis and Biological Validation of a Harmine-Based, Central Nervous System (CNS)-Avoidant, Selective, Human β-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor
- (2020) Kunal Kumar et al. JOURNAL OF MEDICINAL CHEMISTRY
- Identification and Repurposing of Trisubstituted Harmine Derivatives as Novel Inhibitors of Mycobacterium tuberculosis Phosphoserine Phosphatase
- (2020) Elise Pierson et al. MOLECULES
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- (2020) Bruno Lima Giacobbo et al. PSYCHOPHARMACOLOGY
- Structure–Activity Relationships and Biological Evaluation of 7-Substituted Harmine Analogs for Human β-Cell Proliferation
- (2020) Kunal Kumar et al. MOLECULES
- Harmine Ameliorates Cognitive Impairment by Inhibiting NLRP3 Inflammasome Activation and Enhancing the BDNF/TrkB Signaling Pathway in STZ-Induced Diabetic Rats
- (2020) Peifang Liu et al. Frontiers in Pharmacology
- The β-carboline Harmine Induces Actin Dynamic Remodeling and Abrogates the Malignant Phenotype in Tumorigenic Cells
- (2020) Ronan Le Moigne et al. Cells
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- (2020) Swati Jain et al. ACS Omega
- The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities
- (2020) Jacopo Boni et al. Cancers
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- (2019) Liang Guo et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Harmine induced apoptosis in Spodoptera frugiperda Sf9 cells by activating the endogenous apoptotic pathways and inhibiting DNA topoisomerase I activity
- (2019) Benshui Shu et al. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
- Natural alkaloid harmine promotes degradation of Alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation
- (2019) Cui-Zan Cai et al. PHYTOMEDICINE
- in- vitro relationship between serum protein binding to beta-carboline alkaloids: A comparative cytotoxic, spectroscopic and calorimetric assays
- (2019) Tapas Ghosh et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Design and Synthesis of a New Soluble Natural β-Carboline Derivative for Preclinical Study by Intravenous Injection
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- Harmine Suppresses Bladder Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2-Mediated Angiogenesis
- (2019) Hai-rong Cai et al. BIOSCIENCE REPORTS
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- (2019) Xiaofeng Niu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Harmine induces anticancer activity in breast cancer cells via targeting TAZ
- (2019) Yu Ding et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Chemical evidence for the use of multiple psychotropic plants in a 1,000-year-old ritual bundle from South America
- (2019) Melanie J. Miller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2019) Lin-wen Wu et al. OncoTargets and Therapy
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- (2019) Annelise Carvalho et al. DRUG DEVELOPMENT RESEARCH
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- (2019) Yang‐ling Li et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Mechanism-based pharmacokinetics-pharmacodynamics studies of harmine and harmaline on neurotransmitters regulatory effects in healthy rats: Challenge on monoamine oxidase and acetylcholinesterase inhibition
- (2019) Bo Jiang et al. PHYTOMEDICINE
- Synergistic Effects and Mechanisms of Combined Treatment With Harmine Hydrochloride and Azoles for Resistant Candida albicans
- (2019) Xiuyun Li et al. Frontiers in Microbiology
- Natural harmine negatively regulates the developmental signaling network of Drosophila melanogaster (Drosophilidae: Diptera) in vivo
- (2019) Gaofeng Cui et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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- (2019) Ivana Perković et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Harmine promotes molar root development via SMAD1/5/8 phosphorylation
- (2018) Naoki Fujiwara et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Harmines inhibit cancer cell growth through coordinated activation of apoptosis and inhibition of autophagy
- (2018) Xinran Geng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Harmine enhances GABAergic transmission onto basoamygdala projection neurons in mice
- (2018) Wei-Zhu Liu et al. BRAIN RESEARCH BULLETIN
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- (2018) Katie L. Uhl et al. Cancer Cell International
- Pancreatic β Cell Regeneration as a Possible Therapy for Diabetes
- (2018) Cristina Aguayo-Mazzucato et al. Cell Metabolism
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- (2018) Jia Shen et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Haspin: a promising target for the design of inhibitors as potent anticancer drugs
- (2018) Nathalie Gisèle Amoussou et al. DRUG DISCOVERY TODAY
- A novel harmine derivative, N -(4-(hydroxycarbamoyl)benzyl)-1-(4- methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxamide (HBC), as histone deacetylase inhibitor: in vitro antiproliferation, apoptosis induction, cell cycle arrest, and antimetastatic effects
- (2018) Jie-Fei Miao et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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- (2018) Saqlain Haider et al. Future Medicinal Chemistry
- Harmine, a small molecule derived from natural sources, inhibits enterovirus 71 replication by targeting NF-κB pathway
- (2018) Deyan Chen et al. INTERNATIONAL IMMUNOPHARMACOLOGY
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- (2018) Jingjing Zhang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2018) Roudaina Benzekri et al. MICROBIAL PATHOGENESIS
- DNA damage photo-induced by chloroharmine isomers: hydrolysis versus oxidation of nucleobases
- (2018) Juan G. Yañuk et al. ORGANIC & BIOMOLECULAR CHEMISTRY
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- (2018) Hedwig S. Kruitwagen et al. STEM CELLS AND DEVELOPMENT
- Harmine enhances type H vessel formation and prevents bone loss in ovariectomized mice
- (2018) Jie Huang et al. Theranostics
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- (2018) Shu-Ping Li et al. Frontiers in Pharmacology
- Nematicidal effect against Bursaphelenchus xylophilus of harmine quaternary ammonium derivatives, inhibitory activity and molecular docking studies on acetylcholinesterase
- (2018) Yan Xia et al. EUROPEAN JOURNAL OF PLANT PATHOLOGY
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- (2018) Kunal Kumar et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2018) Zachary A. Yochum et al. ONCOGENE
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- (2018) Gaofeng Cui et al. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
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- (2017) Annelise Carvalho et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Potential Antitumor Effect of Harmine in the Treatment of Thyroid Cancer
- (2017) Shu Ruan et al. Evidence-based Complementary and Alternative Medicine
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- (2017) Arezoo Oodi et al. INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION
- In-vitroandin-vivoevaluation of the modulatory effects of the multitarget compound ASS234 on the monoaminergic system
- (2017) Gerard Esteban et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- The Antiviral Effects of Harmine Against BoHV-1 Infection In Vitro
- (2017) Xinyi Jiang et al. Letters in Drug Design & Discovery
- Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin
- (2017) Reham Atteya et al. MECHANISMS OF AGEING AND DEVELOPMENT
- A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer
- (2017) Zachary A. Yochum et al. MOLECULAR CANCER RESEARCH
- Binding of Harmine Derivatives to DNA: A Spectroscopic Investigation
- (2017) Bruno Pagano et al. MOLECULES
- Harmine suppresses the proliferation and migration of human ovarian cancer cells through inhibiting ERK/CREB pathway
- (2017) Jun Gao et al. ONCOLOGY REPORTS
- Harmine promotes periodontal ligament cell-induced tissue regeneration
- (2017) H-C Lim et al. ORAL DISEASES
- Anticancer activities of harmine by inducing a pro-death autophagy and apoptosis in human gastric cancer cells
- (2017) Chuan Li et al. PHYTOMEDICINE
- Harmine produces antidepressant-like effects via restoration of astrocytic functions
- (2017) Fengguo Liu et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Harmine, a Novel DNA Methyltransferase 1 Inhibitor in the Leukemia Cell Line
- (2017) Arezoo Oodi et al. Indian Journal of Hematology and Blood Transfusion
- Exposure Characteristics of the Analogous β-Carboline Alkaloids Harmaline and Harmine Based on the Efflux Transporter of Multidrug Resistance Protein 2
- (2017) Shuping Li et al. Frontiers in Pharmacology
- Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis
- (2017) Chunguang Chen et al. Molecular Metabolism
- A Combined In Vitro Assay for Evaluation of Neurotrophic Activity and Cytotoxicity
- (2017) Narayan D. Chaurasiya et al. SLAS Discovery
- Antiviral activity of natural and synthetic β-carbolines against dengue virus
- (2016) Verónica M. Quintana et al. ANTIVIRAL RESEARCH
- Synthesis and biological evaluation of N9-substituted harmine derivatives as potential anticancer agents
- (2016) Hongtao Du et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Spectroscopic and structural studies on the interaction of an anticancer β–carboline alkaloid, harmine with GC and AT specific DNA oligonucleotides
- (2016) Shweta Sharma et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Inhibition of DYRK1A Stimulates Human β-Cell Proliferation
- (2016) Ercument Dirice et al. DIABETES
- Interspecies metabolic diversity of harmaline and harmine in in vitro 11 mammalian liver microsomes
- (2016) Shuping Li et al. Drug Testing and Analysis
- Synthesis, cytotoxic, anti-lipoxygenase and anti-acetylcholinesterase capacities of novel derivatives from harmine
- (2016) Insaf Filali et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisinin
- (2016) Abebe Genetu Bayih et al. MALARIA JOURNAL
- Harmine induces cell cycle arrest and mitochondrial pathway-mediated cellular apoptosis in SW620 cells via inhibition of the Akt and ERK signaling pathways
- (2016) JIMING LIU et al. ONCOLOGY REPORTS
- Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis
- (2016) Tao Nie et al. Scientific Reports
- Harmine stimulates proliferation of human neural progenitors
- (2016) Vanja Dakic et al. PeerJ
- Synthesis and mechanisms of action of novel harmine derivatives as potential antitumor agents
- (2016) Xiao-Fei Zhang et al. Scientific Reports
- Harmine blocks herpes simplex virus infection through downregulating cellular NF-κB and MAPK pathways induced by oxidative stress
- (2015) Deyan Chen et al. ANTIVIRAL RESEARCH
- Harmine suppresses homologous recombination repair and inhibits proliferation of hepatoma cells
- (2015) Lei Zhang et al. CANCER BIOLOGY & THERAPY
- 3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties
- (2015) Céline Meinguet et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Effects of harmine, an acetylcholinesterase inhibitor, on spatial learning and memory of APP/PS1 transgenic mice and scopolamine-induced memory impairment mice
- (2015) Dandan He et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Involvement of the Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A–Alternative Splicing Factor–Calcium/Calmodulin-Dependent Protein Kinase IIδ Signaling Pathway in Myocardial Infarction-Induced Heart Failure of Rats
- (2015) Jing He et al. JOURNAL OF CARDIAC FAILURE
- Synthesis of New Harmine Isoxazoles and Evaluation of their Potential Anti-Alzheimer, Anti-Inflammatory, and Anticancer Activities
- (2015) Insaf Filali et al. Medicinal Chemistry
- Treatment with harmine ameliorates functional impairment and neuronal death following traumatic brain injury
- (2015) ZEQI ZHONG et al. Molecular Medicine Reports
- A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication
- (2015) Peng Wang et al. NATURE MEDICINE
- DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications
- (2015) Ramzi Abbassi et al. PHARMACOLOGY & THERAPEUTICS
- Harmine treatment enhances short-term memory in old rats: Dissociation of cognition and the ability to perform the procedural requirements of maze testing
- (2015) Sarah E. Mennenga et al. PHYSIOLOGY & BEHAVIOR
- Harmine Hydrochloride Triggers G2 Phase Arrest and Apoptosis in MGC-803 Cells and SMMC-7721 Cells by Upregulating p21, Activating Caspase-8/Bid, and Downregulating ERK/Bad Pathway
- (2015) Peng Zhang et al. PHYTOTHERAPY RESEARCH
- Anti-tumor angiogenesis effect of a new compound: B-9-3 through interference with VEGFR2 signaling
- (2015) Qin Ma et al. TUMOR BIOLOGY
- Paclitaxel combined with harmine inhibits the migration and invasion of gastric cancer cells through downregulation of cyclooxygenase-2 expression
- (2015) KUN SUN et al. Oncology Letters
- Novel harmine derivatives for tumor targeted therapy
- (2015) Siwen Li et al. Oncotarget
- Synthesis and serum protein binding of novel ring-substituted harmine derivatives
- (2015) Celesztina Domonkos et al. RSC Advances
- Selectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors
- (2015) Katharina Rüben et al. PLoS One
- Harmine Lengthens Circadian Period of the Mammalian Molecular Clock in the Suprachiasmatic Nucleus
- (2014) Daisuke Kondoh et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Synthesis of new isoxazoline derivatives from harmine and evaluation of their anti-Alzheimer, anti-cancer and anti-inflammatory activities
- (2014) Insaf Filali et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Intra- and extra-cellular DNA damage by harmine and 9-methyl-harmine
- (2014) Mariana Vignoni et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
- Harmine mediated neuroprotection via evaluation of glutamate transporter 1 in a rat model of global cerebral ischemia
- (2014) Piyun Sun et al. NEUROSCIENCE LETTERS
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- (2013) Helena Mendes Abelaira et al. ACTA NEUROPSYCHIATRICA
- The use of hollow mesoporous silica nanospheres to encapsulate bortezomib and improve efficacy for non-small cell lung cancer therapy
- (2013) Jia Shen et al. BIOMATERIALS
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- (2013) Huailei Liu et al. JOURNAL OF NEURO-ONCOLOGY
- Dosage of Dyrk1a Shifts Cells within a p21-Cyclin D1 Signaling Map to Control the Decision to Enter the Cell Cycle
- (2013) Jia-Yun Chen et al. MOLECULAR CELL
- Harmine induces apoptosis and inhibits tumor cell proliferation, migration and invasion through down-regulation of cyclooxygenase-2 expression in gastric cancer
- (2013) Hao Zhang et al. PHYTOMEDICINE
- Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities ofβ-Carboline and Quinoline Alkaloids Derivatives from the Plants of GenusPeganum
- (2013) Ting Zhao et al. Journal of Chemistry
- The β-carboline alkaloid harmine inhibits telomerase activity of MCF-7 cells by down-regulating hTERT mRNA expression accompanied by an accelerated senescent phenotype
- (2013) Lei Zhao et al. PeerJ
- Harmine Is a Potent Antimalarial Targeting Hsp90 and Synergizes with Chloroquine and Artemisinin
- (2012) Dea Shahinas et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Novel chondrogenic and chondroprotective effects of the natural compound harmine
- (2012) Emilio Satoshi Hara et al. BIOCHIMIE
- Structure–activity relationship study of beta-carboline derivatives as haspin kinase inhibitors
- (2012) Gregory D. Cuny et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and structure–activity relationships of harmine derivatives as potential antitumor agents
- (2012) Rihui Cao et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Metabolic pathways of the psychotropic-carboline alkaloids, harmaline and harmine, by liquid chromatography/mass spectrometry and NMR spectroscopy
- (2012) Ting Zhao et al. FOOD CHEMISTRY
- Harmine induces apoptosis in HepG2 cells via mitochondrial signaling pathway
- (2012) Ming-Rong Cao et al. Hepatobiliary & Pancreatic Diseases International
- Studies on Anti-metastatic and Anti-invasive Effects of Harmine Using Highly Metastatic Murine B16F-10 Melanoma Cells
- (2012) T. P. Hamsa et al. JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY
- Interactions between β-carboline alkaloids and bovine serum albumin: Investigation by spectroscopic approach
- (2012) Shohreh Nafisi et al. JOURNAL OF LUMINESCENCE
- Novel Trisubstituted Harmine Derivatives with Original in Vitro Anticancer Activity
- (2012) Raphaël Frédérick et al. JOURNAL OF MEDICINAL CHEMISTRY
- Harmine augments electrically evoked dopamine efflux in the nucleus accumbens shell
- (2012) Daniel I Brierley et al. JOURNAL OF PSYCHOPHARMACOLOGY
- In vivo comparison of harmine efficacy against psychostimulants: Preferential inhibition of the cocaine response through a glutamatergic mechanism
- (2012) Suzan Owaisat et al. NEUROSCIENCE LETTERS
- JKA97, a Novel Benzylidene Analog of Harmine, Exerts Anti-Cancer Effects by Inducing G1 Arrest, Apoptosis, and p53-Independent Up-Regulation of p21
- (2012) Xinyi Yang et al. PLoS One
- Harmine and Harmaline Downregulate TCDD-Induced Cyp1a1 in the Livers and Lungs of C57BL/6 Mice
- (2012) Mohamed A. M. El Gendy et al. Biomed Research International
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- (2011) Yoshiaki Onishi et al. BIOSCIENCE REPORTS
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- (2011) Hiroshi Egusa et al. BONE
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- (2011) Gislaine Z. Réus et al. Oxidative Medicine and Cellular Longevity
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- (2011) G. K. Mukusheva et al. PHARMACEUTICAL CHEMISTRY JOURNAL
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- (2011) Ting Zhao et al. PHYTOTHERAPY RESEARCH
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- (2011) Danielle Frost et al. PLoS One
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- (2011) Mohamed A.M. El Gendy et al. TOXICOLOGY LETTERS
- Harmine activates intrinsic and extrinsic pathways of apoptosis in B16F-10 melanoma
- (2011) Thayele Hamsa et al. Chinese Medicine
- Harmine is an ATP-competitive inhibitor for dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A)
- (2010) Tatyana Adayev et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Synthesis and evaluation of β-carboline derivatives as potential monoamine oxidase inhibitors
- (2010) J. Reniers et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Harmine inhibits tumour specific neo-vessel formation by regulating VEGF, MMP, TIMP and pro-inflammatory mediators both in vivo and in vitro
- (2010) T.P. Hamsa et al. EUROPEAN JOURNAL OF PHARMACOLOGY
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- (2010) Takayuki Yonezawa et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Antibacterial and antifungal activities of (beta)-carboline alkaloids of Peganum harmala (L) seeds and their combination effects
- (2010) Gomah Nenaah FITOTERAPIA
- Chronic administration of harmine elicits antidepressant-like effects and increases BDNF levels in rat hippocampus
- (2010) Jucélia J. Fortunato et al. JOURNAL OF NEURAL TRANSMISSION
- β-Carboline alkaloids bind DNA
- (2010) Shohreh Nafisi et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
- Cytotoxic and Insecticidal Activities of Derivatives of Harmine, a Natural Insecticidal Component Isolated from Peganum harmala
- (2010) Yong Zeng et al. MOLECULES
- Harmine, a natural beta-carboline alkaloid, upregulates astroglial glutamate transporter expression
- (2010) Yun Li et al. NEUROPHARMACOLOGY
- Effects of β-carboline harmine on behavioral and physiological parameters observed in the chronic mild stress model: Further evidence of antidepressant properties
- (2009) Jucélia J. Fortunato et al. BRAIN RESEARCH BULLETIN
- Function and regulation of Dyrk1A: towards understanding Down syndrome
- (2009) Joongkyu Park et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation
- (2009) Nora Göckler et al. FEBS Journal
- The beta-carboline alkaloid harmine inhibits BCRP and can reverse resistance to the anticancer drugs mitoxantrone and camptothecin in breast cancer cells
- (2009) Yonggang Ma et al. PHYTOTHERAPY RESEARCH
- Acute harmine administration induces antidepressive-like effects and increases BDNF levels in the rat hippocampus
- (2009) Jucélia J. Fortunato et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Cytotoxicity of the β-carboline alkaloids harmine and harmaline in human cell assays in vitro
- (2008) Judith Jiménez et al. EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY
- DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine
- (2008) Anne Seifert et al. FEBS Journal
- Antiplatelet activity of β-carboline alkaloids from Perganum harmala: A possible mechanism through inhibiting PLCγ2 phosphorylation
- (2008) Ji-Hyun Im et al. VASCULAR PHARMACOLOGY
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