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Title
PCSK9: Associated with cardiac diseases and their risk factors?
Authors
Keywords
PCSK9, Cardiac diseases, Risk factors, Cardiomyocyte, Inflammation
Journal
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Volume -, Issue -, Pages 108717
Publisher
Elsevier BV
Online
2020-12-09
DOI
10.1016/j.abb.2020.108717
References
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- (2019) Cory Trankle et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
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- (2018) Zufeng Ding et al. CARDIOVASCULAR RESEARCH
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- (2018) Johan Ljungberg et al. CIRCULATION
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- (2018) Lorenzo Da Dalt et al. EUROPEAN HEART JOURNAL
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- (2018) Shirley Dehn et al. FASEB JOURNAL
- A potential relationship between gut microbes and atrial fibrillation: Trimethylamine N-oxide, a gut microbe-derived metabolite, facilitates the progression of atrial fibrillation
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- (2018) Gard F.T. Svingen et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
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- (2018) Veronika A. Myasoedova et al. PHARMACOLOGICAL RESEARCH
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- (2018) Sung Woo Kim et al. Diabetes & Metabolism Journal
- PCSK9 Involvement in Aortic Valve Calcification
- (2018) Paolo Poggio et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Long-term exposure to air pollution raises circulating levels of proprotein convertase subtilisin/kexin type 9 in obese individuals
- (2018) Chiara Macchi et al. European Journal of Preventive Cardiology
- Pressure Overload Impairs Cardiac Function in Long-Chain Fatty Acid Transporter CD36-Knockout Mice
- (2018) Kazuhiro Nakatani et al. International Heart Journal
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- Acute and Chronic Impact of Bariatric Surgery on Plasma LDL Cholesterol and PCSK9 Levels in Patients With Severe Obesity
- (2017) Marjorie Boyer et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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- (2017) Daniele Pastori et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
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- (2017) Amy E. Levenson et al. PEDIATRIC DIABETES
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- (2015) Kristine Y. DeLeon-Pennell et al. Circulation-Cardiovascular Genetics
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- (2015) T.C. Ooi et al. CLINICA CHIMICA ACTA
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- (2015) Christel H. Kamani et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Lipoprotein(a) Catabolism Is Regulated by Proprotein Convertase Subtilisin/Kexin Type 9 through the Low Density Lipoprotein Receptor
- (2015) Rocco Romagnuolo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Understanding PCSK9 and anti-PCSK9 therapies
- (2015) James M. McKenney Journal of Clinical Lipidology
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- (2015) Vikram Ravindra Shende et al. JOURNAL OF LIPID RESEARCH
- Local effects of human PCSK9 on the atherosclerotic lesion
- (2015) Ilaria Giunzioni et al. JOURNAL OF PATHOLOGY
- The lipid theory in the pathogenesis of calcific aortic stenosis
- (2015) V. Parisi et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- CD36 Is a Matrix Metalloproteinase-9 Substrate That Stimulates Neutrophil Apoptosis and Removal During Cardiac RemodelingCLINICAL PERSPECTIVE
- (2015) Kristine Y. DeLeon-Pennell et al. Circulation-Cardiovascular Genetics
- PCSK9 variation and association with blood pressure in African Americans: preliminary findings from the HyperGEN and REGARDS studies
- (2015) Ngan T. Tran et al. Frontiers in Genetics
- Proprotein convertase subtilisin/kexin type 9 expression is transiently up-regulated in the acute period of myocardial infarction in rat
- (2015) Yan Zhang et al. BMC Cardiovascular Disorders
- Association of plasma PCSK9 levels with white blood cell count and its subsets in patients with stable coronary artery disease
- (2014) Sha Li et al. ATHEROSCLEROSIS
- The Sirt1 activator SRT3025 provides atheroprotection in Apoe−/− mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression
- (2014) Melroy X. Miranda et al. EUROPEAN HEART JOURNAL
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- (2014) J. Gustav Smith et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
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- (2014) Moumita Ghosh et al. JOURNAL OF LIPID RESEARCH
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- (2014) Victoria Ulrich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2013) Kyubok Jin et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- AMG145, a Monoclonal Antibody Against Proprotein Convertase Subtilisin Kexin Type 9, Significantly Reduces Lipoprotein(a) in Hypercholesterolemic Patients Receiving Statin Therapy
- (2013) Nihar R. Desai et al. CIRCULATION
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- (2013) Rongya Tao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2013) Rongya Tao et al. JOURNAL OF LIPID RESEARCH
- Elevated Expression of Lipoprotein-Associated Phospholipase A2 in Calcific Aortic Valve Disease
- (2013) Ablajan Mahmut et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Antithrombin is protective against myocardial ischemia and reperfusion injury
- (2013) J. Wang et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- Cholesteryl Esters Accumulate in the Heart in a Porcine Model of Ischemia and Reperfusion
- (2013) Christina Drevinge et al. PLoS One
- Plasma Lipoprotein-associated Phospholipase A2 Is Inversely Correlated with Proprotein Convertase Subtilisin-kexin Type 9
- (2012) Alexander Constantinides et al. ARCHIVES OF MEDICAL RESEARCH
- The novel function of HINFP as a co-activator in sterol-regulated transcription ofPCSK9in HepG2 cells
- (2012) Hai Li et al. BIOCHEMICAL JOURNAL
- Low-density lipoprotein receptor-related protein 1 mediates hypoxia-induced very low density lipoprotein-cholesteryl ester uptake and accumulation in cardiomyocytes
- (2012) Roi Cal et al. CARDIOVASCULAR RESEARCH
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- (2012) Arjan J. Kwakernaak et al. CLINICAL BIOCHEMISTRY
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- (2012) Rui-Xing Yin et al. International Journal of Biological Sciences
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- (2012) Terri A. Pietka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Vikas Sharotri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Yajun Duan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Michelle Melone et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Low density lipoprotein receptor-related protein 1 expression correlates with cholesteryl ester accumulation in the myocardium of ischemic cardiomyopathy patients
- (2012) Roi Cal et al. Journal of Translational Medicine
- Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
- (2012) Benjamin F Voight et al. LANCET
- Adiposity Blunts the Positive Relationship of Thyrotropin with Proprotein Convertase Subtilisin-Kexin Type 9 Levels in Euthyroid Subjects
- (2012) Arjan J. Kwakernaak et al. THYROID
- Induction of brain natriuretic peptide and monocyte chemotactic protein-1 gene expression by oxidized low-density lipoprotein: relevance to ischemic heart failure
- (2011) Aluganti N. Chandrakala et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Plasma proprotein convertase subtilisin kexin type 9 is not altered in subjects with impaired glucose metabolism and type 2 diabetes mellitus, but its relationship with non-HDL cholesterol and apolipoprotein B may be modified by type 2 diabetes mellitus: The CODAM study
- (2011) M.C.G.J. Brouwers et al. ATHEROSCLEROSIS
- Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia–reperfusion injury
- (2011) Stefano Toldo et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
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- (2010) Bertrand Cariou et al. ATHEROSCLEROSIS
- Serum PCSK9 is associated with multiple metabolic factors in a large Han Chinese population
- (2010) Qin Cui et al. ATHEROSCLEROSIS
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- (2010) Kwan Leung Chan et al. CIRCULATION
- Strong induction of PCSK9 gene expression through HNF1α and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters
- (2010) Bin Dong et al. JOURNAL OF LIPID RESEARCH
- Plasma PCSK9 Is Associated with Age, Sex, and Multiple Metabolic Markers in a Population-Based Sample of Children and Adolescents
- (2009) A. Baass et al. CLINICAL CHEMISTRY
- Hepatocyte Nuclear Factor 1α Plays a Critical Role inPCSK9Gene Transcription and Regulation by the Natural Hypocholesterolemic Compound Berberine
- (2009) Hai Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genetic and Metabolic Determinants of Plasma PCSK9 Levels
- (2009) Susan G. Lakoski et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Prognosis and Risk Factors in Patients With Asymptomatic Aortic Stenosis and Their Modulation by Atorvastatin (20 mg)
- (2008) Wolfgang Dichtl et al. AMERICAN JOURNAL OF CARDIOLOGY
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- (2008) Kenneth R. Feingold et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Angiotensin-Receptor Blockade Reduces Border Zone Myocardial Monocyte Chemoattractant Protein-1 Expression and Macrophage Infiltration in Post-Infarction Ventricular Remodeling
- (2008) Takashi Kohno et al. CIRCULATION JOURNAL
- Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes
- (2008) Cédric Langhi et al. FEBS LETTERS
- Intensive Lipid Lowering with Simvastatin and Ezetimibe in Aortic Stenosis
- (2008) Anne B. Rossebø et al. NEW ENGLAND JOURNAL OF MEDICINE
- APCSK9Missense Variant Associated with a Reduced Risk of Early-Onset Myocardial Infarction
- (2008) Sekar Kathiresan NEW ENGLAND JOURNAL OF MEDICINE
- Diabetes alters LDL receptor and PCSK9 expression in rat liver
- (2007) Melissa Niesen et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
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