Long-term exposure to air pollution raises circulating levels of proprotein convertase subtilisin/kexin type 9 in obese individuals

Self-initiated physical activity is associated with high sensitivity C-reactive protein: A longitudinal study in 5,030 adults

(2018) Rômulo Araújo Fernandes et al.   ATHEROSCLEROSIS

Plasma PCSK9 levels and lipoprotein distribution are preserved in carriers of genetic HDL disorders

(2018) Massimiliano Ruscica et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Developing a Clinical Approach to Air Pollution and Cardiovascular Health

(2018) Michael B. Hadley et al.   CIRCULATION

Impact of Particulate Air Pollution on Cardiovascular Health

(2018) Zhen An et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Acute particulate matter affects cardiovascular autonomic modulation and IFN-γ methylation in healthy volunteers

(2018) Eleonora Tobaldini et al.   ENVIRONMENTAL RESEARCH

Serum PCSK9 levels predict the occurrence of acute coronary syndromes in patients with severe carotid artery stenosis

(2018) Luca Liberale et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

PCSK9 as a Positive Modulator of Platelet Activation

(2018) Marina Camera et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Lancet Commission on pollution and health

(2018) Philip J Landrigan et al.   LANCET

Beyond LDL: What Role for PCSK9 in Triglyceride-Rich Lipoprotein Metabolism?

(2018) Wieneke Dijk et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

PCSK9 induces a pro-inflammatory response in macrophages

(2018) Chiara Ricci et al.   Scientific Reports

Ambient air pollution and cardiovascular diseases: From bench to bedside

(2018) Simone Vidale et al.   European Journal of Preventive Cardiology

Ambient air pollution as a new risk factor for cardiovascular diseases: Time to take action

(2018) Mariantonietta Cicoira   European Journal of Preventive Cardiology

Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice

(2018) José Tuñón et al.   European Journal of Preventive Cardiology

High circulating proprotein convertase subtilisin/Kexin type 9 concentration associates with cardiovascular risk

(2017) Chengfeng Qiu et al.   MEDICINE

Extracellular vesicle-packaged miRNA release after short-term exposure to particulate matter is associated with increased coagulation

(2017) Laura Pergoli et al.   Particle and Fibre Toxicology

Air pollution levels and cardiovascular health: Low is not enough

(2017) Pier Mannuccio Mannucci   European Journal of Preventive Cardiology

Circulating Levels of Proprotein Convertase Subtilisin/Kexin Type 9 and Arterial Stiffness in a Large Population Sample: Data From the Brisighella Heart Study

(2017) Massimiliano Ruscica et al.   Journal of the American Heart Association

Proprotein Convertase Subtilisin/Kexin 9 Levels in Relation to Systemic Immune Activation and Subclinical Coronary Plaque in HIV

(2017) Markella V Zanni et al.   Open Forum Infectious Diseases

PCSK9 knock-out mice are protected from neointimal formation in response to perivascular carotid collar placement

(2016) Nicola Ferri et al.   ATHEROSCLEROSIS

Prediction of cardiovascular events with levels of proprotein convertase subtilisin/kexin type 9: A systematic review and meta-analysis

(2016) Charalambos Vlachopoulos et al.   ATHEROSCLEROSIS

Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Predicts Future Risk of Cardiovascular Events Independently of Established Risk FactorsCLINICAL PERSPECTIVE

(2016) Karin Leander et al.   CIRCULATION

Reducing burden of disease from residential indoor air exposures in Europe (HEALTHVENT project)

(2016) Arja Asikainen et al.   Environmental Health

Association of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) With Cardiovascular Risk in Primary PreventionSignificance

(2015) Yiming M. Zhu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ambient Air Pollution Exposure Estimation for the Global Burden of Disease 2013

(2015) Michael Brauer et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Prognostic value of PCSK9 levels in patients with acute coronary syndromes

(2015) Baris Gencer et al.   EUROPEAN HEART JOURNAL

Plasma proprotein convertase subtilisin/kexin type 9 levels and the risk of first cardiovascular events

(2015) Paul M. Ridker et al.   EUROPEAN HEART JOURNAL

Suppressor of Cytokine Signaling-3 (SOCS-3) Induces Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Expression in Hepatic HepG2 Cell Line

(2015) Massimiliano Ruscica et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Susceptibility to particle health effects, miRNA and exosomes: rationale and study protocol of the SPHERE study

(2014) Valentina Bollati et al.   BMC PUBLIC HEALTH

Cardiovascular effects of environmental noise exposure

(2014) T. Munzel et al.   EUROPEAN HEART JOURNAL

Expert position paper on air pollution and cardiovascular disease

(2014) David E. Newby et al.   EUROPEAN HEART JOURNAL

Obesity and the cardiovascular health effects of fine particulate air pollution

(2014) Scott Weichenthal et al.   Obesity

Risk prediction with proprotein convertase subtilisin/kexin type 9 (PCSK9) in patients with stable coronary disease on statin treatment

(2014) Christian Werner et al.   VASCULAR PHARMACOLOGY

Overview of Epidemiology and Contribution of Obesity to Cardiovascular Disease

(2013) Marjorie Bastien et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels

(2011) Nicola Ferri et al.   ATHEROSCLEROSIS

Circulating Proprotein Convertase Subtilisin Kexin Type 9 Has a Diurnal Rhythm Synchronous With Cholesterol Synthesis and Is Reduced by Fasting in Humans

(2010) Lena Persson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Particulate Matter Air Pollution and Cardiovascular Disease

(2010) Robert D. Brook et al.   CIRCULATION

Plasma PCSK9 Is Associated with Age, Sex, and Multiple Metabolic Markers in a Population-Based Sample of Children and Adolescents

(2009) A. Baass et al.   CLINICAL CHEMISTRY

Epigenetics and environmental chemicals

(2009) Andrea Baccarelli et al.   CURRENT OPINION IN PEDIATRICS

Genetic and Metabolic Determinants of Plasma PCSK9 Levels

(2009) Susan G. Lakoski et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Differences in cytotoxicity versus pro-inflammatory potency of different PM fractions in human epithelial lung cells

(2009) Maurizio Gualtieri et al.   TOXICOLOGY IN VITRO

General Cardiovascular Risk Profile for Use in Primary Care

(2008) Ralph B. D’Agostino et al.   CIRCULATION