Acute and Chronic Impact of Bariatric Surgery on Plasma LDL Cholesterol and PCSK9 Levels in Patients With Severe Obesity

Changes in Lipid Profile of Obese Patients Following Contemporary Bariatric Surgery: A Meta-Analysis

(2016) Sean P. Heffron et al.   AMERICAN JOURNAL OF MEDICINE

Liver fat accumulation is associated with circulating PCSK9

(2016) Massimiliano Ruscica et al.   ANNALS OF MEDICINE

Bile Acids Increase Independently From Hypocaloric Restriction After Bariatric Surgery

(2016) Cyrus Jahansouz et al.   ANNALS OF SURGERY

Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Predicts Future Risk of Cardiovascular Events Independently of Established Risk FactorsCLINICAL PERSPECTIVE

(2016) Karin Leander et al.   CIRCULATION

Enhanced pro-protein convertase subtilisin/kexin type 9 expression by C-reactive protein through p38MAPK-HNF1α pathway in HepG2 cells

(2016) Chuan-Jue Cui et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Impact of a 1-year lifestyle modification program on plasma lipoprotein and PCSK9 concentrations in patients with coronary artery disease

(2016) Marjorie Boyer et al.   Journal of Clinical Lipidology

Leptin decreases the expression of low-density lipoprotein receptor via PCSK9 pathway: linking dyslipidemia with obesity

(2016) Ying Du et al.   Journal of Translational Medicine

Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

(2016)   LANCET

Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9Significance

(2015) Ji Miao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effect of statin therapy on plasma proprotein convertase subtilisin kexin 9 (PCSK9) concentrations: a systematic review and meta-analysis of clinical trials

(2015) A. Sahebkar et al.   DIABETES OBESITY & METABOLISM

Positive correlation of plasma PCSK9 levels with HbA1cin patients with type 2 diabetes

(2015) Sheng-Hua Yang et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

The loss-of-function PCSK9 p.R46L genetic variant does not alter glucose homeostasis

(2015) Amélie Bonnefond et al.   DIABETOLOGIA

Prognostic value of PCSK9 levels in patients with acute coronary syndromes

(2015) Baris Gencer et al.   EUROPEAN HEART JOURNAL

Familial hypercholesterolemia: PCSK9 InsLEU genetic variant and prediabetes/diabetes risk

(2015) Yascara G. Luna Saavedra et al.   Journal of Clinical Lipidology

A semi-automated mass spectrometric immunoassay coupled to selected reaction monitoring (MSIA–SRM) reveals novel relationships between circulating PCSK9 and metabolic phenotypes in patient cohorts

(2015) Marie-Soleil Gauthier et al.   METHODS

A Systematic Review and Meta-analysis of the Effect of Gastric Bypass Surgery on Plasma Lipid Levels

(2015) Kirstin A. Carswell et al.   OBESITY SURGERY

Proprotein convertase subtilisin/kexin type 9 expression is transiently up-regulated in the acute period of myocardial infarction in rat

(2015) Yan Zhang et al.   BMC Cardiovascular Disorders

Intestinal Lipid Handling

(2014) Alain Veilleux et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

PCSK9 levels in abdominally obese men: Association with cardiometabolic risk profile and effects of a one-year lifestyle modification program

(2014) Benoit J. Arsenault et al.   ATHEROSCLEROSIS

PCSK9

(2014) Nabil G. Seidah et al.   CIRCULATION RESEARCH

Biliopancreatic diversion with duodenal switch improves insulin sensitivity and secretion through caloric restriction

(2014) Charles-Étienne Plourde et al.   Obesity

PCSK9 plays a significant role in cholesterol homeostasis and lipid transport in intestinal epithelial cells

(2013) Emile Levy et al.   ATHEROSCLEROSIS

Changes in predicted cardiovascular disease risk after biliopancreatic diversion surgery in severely obese patients

(2013) Marie-Ève Piché et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Plasma PCSK9 concentrations during an oral fat load and after short term high-fat, high-fat high-protein and high-fructose diets

(2013) Bertrand Cariou et al.   Nutrition & Metabolism

Bariatric Surgery and Long-term Cardiovascular Events

(2012) Lars Sjöström et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Discovery of a New Role of Human Resistin in Hepatocyte Low-Density Lipoprotein Receptor Suppression Mediated in Part by Proprotein Convertase Subtilisin/Kexin Type 9

(2012) Michelle Melone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Plasma proprotein convertase subtilisin kexin type 9 is not altered in subjects with impaired glucose metabolism and type 2 diabetes mellitus, but its relationship with non-HDL cholesterol and apolipoprotein B may be modified by type 2 diabetes mellitus: The CODAM study

(2011) M.C.G.J. Brouwers et al.   ATHEROSCLEROSIS

Effect of the Mediterranean diet with and without weight loss on surrogate markers of cholesterol homeostasis in men with the metabolic syndrome

(2011) Caroline Richard et al.   BRITISH JOURNAL OF NUTRITION

Bariatric Surgery and Cardiovascular Risk Factors

(2011) Paul Poirier et al.   CIRCULATION

Fasting reduces plasma proprotein convertase, subtilisin/kexin type 9 and cholesterol biosynthesis in humans

(2010) Jeffrey D. Browning et al.   JOURNAL OF LIPID RESEARCH

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Weight and Type 2 Diabetes after Bariatric Surgery: Systematic Review and Meta-analysis

(2009) Henry Buchwald et al.   AMERICAN JOURNAL OF MEDICINE

Regulation of the proprotein convertase subtilisin/kexin type 9 in intestinal epithelial cells

(2009) François Leblond et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Genetic and Metabolic Determinants of Plasma PCSK9 Levels

(2009) Susan G. Lakoski et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM