Nuclear factor erythroid 2-related factor 2 (Nrf2) as a potential therapeutic target for vitiligo
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Title
Nuclear factor erythroid 2-related factor 2 (Nrf2) as a potential therapeutic target for vitiligo
Authors
Keywords
Vitiligo, Oxidative stress, Nuclear factor erythroid2-related factor, Kelch-like ECH-Associated protein 1, Antioxidant responsive element, Potential therapeutic target
Journal
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
Volume 696, Issue -, Pages 108670
Publisher
Elsevier BV
Online
2020-11-11
DOI
10.1016/j.abb.2020.108670
References
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Note: Only part of the references are listed.- Apigenin protects human melanocytes against oxidative damage by activation of the Nrf2 pathway
- (2020) Baoxiang Zhang et al. CELL STRESS & CHAPERONES
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- (2020) Shimaa Saad El-Din et al. STEROIDS
- Paeoniflorin Resists H2O2-Induced Oxidative Stress in Melanocytes by JNK/Nrf2/HO-1 Pathway
- (2020) Jinping Yuan et al. Frontiers in Pharmacology
- Flavolignans from Silymarin as Nrf2 Bioactivators and Their Therapeutic Applications
- (2020) Nancy Vargas-Mendoza et al. Biomedicines
- Berberine protects immortalized line of human melanocytes from H2O2-induced oxidative stress via activation of Nrf2 and Mitf signaling pathway
- (2019) Wei Jiang et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Can we consider silymarin as a treatment option for vitiligo? A double-blind controlled randomized clinical trial of phototherapy plus oral Silybum marianum product versus phototherapy alone
- (2019) Farideh Jowkar et al. JOURNAL OF DERMATOLOGICAL TREATMENT
- Ginkgo biloba extract protects human melanocytes from H 2 O 2 ‐induced oxidative stress by activating Nrf2
- (2019) Shaolong Zhang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development
- (2019) Natalia Robledinos-Antón et al. Oxidative Medicine and Cellular Longevity
- Evidence of a possible therapeutic role of vitamin D in a cohort of adult Caucasian vitiligo patients
- (2019) Roberta Colucci et al. INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH
- Nrf2–ARE signaling in cellular protection: Mechanism of action and the regulatory mechanisms
- (2019) Pallab Shaw et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Curcumin activates the Nrf2 pathway and induces cellular protection against oxidative injury
- (2019) Milad Ashrafizadeh et al. CURRENT MOLECULAR MEDICINE
- The convergence theory for vitiligo: A reappraisal
- (2018) Roopal V. Kundu et al. EXPERIMENTAL DERMATOLOGY
- Role of Vitamin D Beyond the Skeletal Function: A Review of the Molecular and Clinical Studies
- (2018) Meenakshi Umar et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Glycyrrhizin ameliorates high fat diet-induced obesity in rats by activating NrF2 pathway
- (2018) Nada F. Abo El-Magd et al. LIFE SCIENCES
- The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
- (2018) Masayuki Yamamoto et al. PHYSIOLOGICAL REVIEWS
- The effect of topical piperine combined with narrowband UVB on vitiligo treatment: A clinical trial study
- (2018) Anoosh Shafiee et al. PHYTOTHERAPY RESEARCH
- Role of ROS and Nutritional Antioxidants in Human Diseases
- (2018) Zewen Liu et al. Frontiers in Physiology
- Vitamin D protects human melanocytes against oxidative damage by activation of Wnt/β-catenin signaling
- (2018) Luyan Tang et al. LABORATORY INVESTIGATION
- Molecular and cellular basis of depigmentation in vitiligo patients
- (2018) Véronique Delmas et al. EXPERIMENTAL DERMATOLOGY
- Baicalein protects human vitiligo melanocytes from oxidative stress through activation of NF-E2-related factor2 (Nrf2) signaling pathway
- (2018) Jingjing Ma et al. FREE RADICAL BIOLOGY AND MEDICINE
- Melanocyte-protective effect of afzelin is mediated by the Nrf2-ARE signalling pathway via GSK-3β inactivation
- (2017) Eunsun Jung et al. EXPERIMENTAL DERMATOLOGY
- The nuclear factor (erythroid-derived 2)-like 2 (NRF2) antioxidant response promotes melanocyte viability and reduces toxicity of the vitiligo-inducing phenol monobenzone
- (2017) Omotayo A. Arowojolu et al. EXPERIMENTAL DERMATOLOGY
- Piperine attenuates lipopolysaccharide (LPS)-induced inflammatory responses in BV2 microglia
- (2017) Chen Wang-sheng et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Simvastatin Protects Human Melanocytes from H 2 O 2 -Induced Oxidative Stress by Activating Nrf2
- (2017) Yuqian Chang et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- SP600125 suppresses Keap1 expression and results in NRF2-mediated prevention of diabetic nephropathy
- (2017) Huan Zhang et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- NRF2 Plays a Critical Role in Both Self and EGCG Protection against Diabetic Testicular Damage
- (2017) Chenyu Pan et al. Oxidative Medicine and Cellular Longevity
- Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways
- (2017) Zorica Janjetovic et al. Scientific Reports
- Combination therapy of orally administered glycyrrhizin and UVB improved active-stage generalized vitiligo
- (2016) K.H. Mou et al. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
- The oxidative stress theory of disease: levels of evidence and epistemological aspects
- (2016) Pietro Ghezzi et al. BRITISH JOURNAL OF PHARMACOLOGY
- Aspirin induces Nrf2-mediated transcriptional activation of haem oxygenase-1 in protection of human melanocytes from H2O2-induced oxidative stress
- (2016) Zhe Jian et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Vitiligo: How do oxidative stress-induced autoantigens trigger autoimmunity?
- (2016) Heng Xie et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Tacalcitol: a useful adjunct to narrow-band ultraviolet-B phototherapy in vitiligo
- (2016) Priyadarshini Sahu et al. PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE
- Stabilization of endogenous Nrf2 by minocycline protects against Nlrp3-inflammasome induced diabetic nephropathy
- (2016) Khurrum Shahzad et al. Scientific Reports
- Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway
- (2015) B.G. Richardson et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Structural basis of Keap1 interactions with Nrf2
- (2015) Peter Canning et al. FREE RADICAL BIOLOGY AND MEDICINE
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- Histopathological characteristics of post kala-azar dermal leishmaniasis: A series of 88 patients
- (2015) Avninder Singh et al. Indian Journal of Dermatology Venereology & Leprology
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- (2015) Young Min Kim et al. INTERNATIONAL IMMUNOPHARMACOLOGY
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- (2015) Loretta O. Iniaghe et al. NEUROBIOLOGY OF DISEASE
- Afamelanotide and Narrowband UV-B Phototherapy for the Treatment of Vitiligo
- (2015) Henry W. Lim et al. JAMA Dermatology
- The therapeutic effects of EGCG on vitiligo
- (2014) Yiping Zhu et al. FITOTERAPIA
- Oxidative Stress and Vitiligo: The Nrf2–ARE Signaling Connection
- (2014) Lei Qiu et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Impaired Activation of the Nrf2-ARE Signaling Pathway Undermines H 2 O 2 -Induced Oxidative Stress Response: A Possible Mechanism for Melanocyte Degeneration in Vitiligo
- (2014) Zhe Jian et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Comparison of efficacy and safety profile of topical calcipotriol ointment in combination with NB-UVB vs. NB-UVB alone in the treatment of vitiligo: a 24-week prospective right-left comparative clinical trial
- (2014) G. Khullar et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- Vitamin D Activates the Nrf2-Keap1 Antioxidant Pathway and Ameliorates Nephropathy in Diabetic Rats
- (2013) K. Nakai et al. AMERICAN JOURNAL OF HYPERTENSION
- Minocycline: far beyond an antibiotic
- (2013) N Garrido-Mesa et al. BRITISH JOURNAL OF PHARMACOLOGY
- Antioxidant Therapy: Current Status and Future Prospects
- (2012) O. Firuzi et al. CURRENT MEDICINAL CHEMISTRY
- Minocycline-Preconditioned Neural Stem Cells Enhance Neuroprotection after Ischemic Stroke in Rats
- (2012) H. Sakata et al. JOURNAL OF NEUROSCIENCE
- The Efficacy of Afamelanotide and Narrowband UV-B Phototherapy for Repigmentation of Vitiligo
- (2012) Pearl E. Grimes et al. JAMA Dermatology
- Ginkgo biloba for the treatment of vitilgo vulgaris: an open label pilot clinical trial
- (2011) Orest Szczurko et al. BMC Complementary and Alternative Medicine
- Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
- (2011) Keiko Taguchi et al. GENES TO CELLS
- Heme Oxygenase-1 Protects Human Melanocytes from H2O2-Induced Oxidative Stress via the Nrf2-ARE Pathway
- (2011) Zhe Jian et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Oral minocycline in the treatment of vitiligo - A preliminary study
- (2010) Davinder Parsad et al. Dermatologic Therapy
- Tetrahydrocurcuminoid Cream Plus Targeted Narrowband UVB Phototherapy for Vitiligo: A Preliminary Randomized Controlled Study
- (2010) Pravit Asawanonda et al. PHOTOMEDICINE AND LASER SURGERY
- Randomized, double-blind clinical trial to evaluate the efficacy of topical tacalcitol and sunlight exposure in the treatment of adult nonsegmental vitiligo
- (2009) M. Rodríguez-Martín et al. BRITISH JOURNAL OF DERMATOLOGY
- α-Melanocyte-Stimulating Hormone Counteracts the Suppressive Effect of UVB on Nrf2 and Nrf-Dependent Gene Expression in Human Skin
- (2009) Agatha Kokot et al. ENDOCRINOLOGY
- The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress
- (2009) Truyen Nguyen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In vivo evaluation of piperine and synthetic analogues as potential treatments for vitiligo using a sparsely pigmented mouse model
- (2008) L. Faas et al. BRITISH JOURNAL OF DERMATOLOGY
- Cellular and Molecular Mechanisms Involved in the Action of Vitamin D Analogs Targeting Vitiligo Depigmentation
- (2008) S. Birlea et al. CURRENT DRUG TARGETS
- Presence of epidermal allantoin further supports oxidative stress in vitiligo
- (2008) Mohammad Shalbaf et al. EXPERIMENTAL DERMATOLOGY
- The susceptibility to vitiligo is associated with NF-E2-related factor2 (Nrf2) gene polymorphisms: a study on Chinese Han population
- (2008) Cui-Ping Guan et al. EXPERIMENTAL DERMATOLOGY
- Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG
- (2007) Hye-Kyung Na et al. FOOD AND CHEMICAL TOXICOLOGY
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