The nuclear factor (erythroid-derived 2)-like 2 (NRF2) antioxidant response promotes melanocyte viability and reduces toxicity of the vitiligo-inducing phenol monobenzone

Aspirin induces Nrf2-mediated transcriptional activation of haem oxygenase-1 in protection of human melanocytes from H2O2-induced oxidative stress

(2016) Zhe Jian et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA)

(2016) John E. Harris et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Recent advances in the biomedical applications of fumaric acid and its ester derivatives: The multifaceted alternative therapeutics

(2016) Ratul Kumar Das et al.   Pharmacological Reports

NAD(P)H dehydrogenase, quinone 1 (NQO1), protects melanin-producing cells from cytotoxicity of rhododendrol

(2016) Ayaka Okubo et al.   Pigment Cell & Melanoma Research

Dimethyl fumarate in the treatment of relapsing–remitting multiple sclerosis: an overview

(2015) Roberto Bomprezzi   Therapeutic Advances in Neurological Disorders

Vitiligo

(2015) Mauro Picardo et al.   Nature Reviews Disease Primers

Immunology of Psoriasis

(2014) Michelle A. Lowes et al.   Annual Review of Immunology

Impaired Activation of the Nrf2-ARE Signaling Pathway Undermines H 2 O 2 -Induced Oxidative Stress Response: A Possible Mechanism for Melanocyte Degeneration in Vitiligo

(2014) Zhe Jian et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

A mouse model of vitiligo induced by monobenzone

(2013) Yiping Zhu et al.   EXPERIMENTAL DERMATOLOGY

Loss ofOca2disrupts the unfolded protein response and increases resistance to endoplasmic reticulum stress in melanocytes

(2013) Tsing Cheng et al.   Pigment Cell & Melanoma Research

Vitiligo: A Possible Model of Degenerative Diseases

(2013) Barbara Bellei et al.   PLoS One

Vitiligo-Inducing Phenols Activate the Unfolded Protein Response in Melanocytes Resulting in Upregulation of IL6 and IL8

(2012) Siavash Toosi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

NAD(P)H:quinone oxidoreductase 1 (NQO1) in the sensitivity and resistance to antitumor quinones

(2011) David Siegel et al.   BIOCHEMICAL PHARMACOLOGY

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

(2011) Ralf A. Linker et al.   BRAIN

NAD(P)H:Quinone Oxidoreductase 1 and its Potential Protective Role in Cardiovascular Diseases and Related Conditions

(2011) Hong Zhu et al.   Cardiovascular Toxicology

Heme oxygenase-1 expression protects melanocytes from stress-induced cell death: implications for vitiligo

(2011) Yasser E. Elassiuty et al.   EXPERIMENTAL DERMATOLOGY

Heme Oxygenase-1 Protects Human Melanocytes from H2O2-Induced Oxidative Stress via the Nrf2-ARE Pathway

(2011) Zhe Jian et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Topical application of bleaching phenols; in-vivo studies and mechanism of action relevant to melanoma treatment

(2011) Vidhya Hariharan et al.   MELANOMA RESEARCH

Monobenzone-induced depigmentation: from enzymatic blockade to autoimmunity

(2011) Jasper G. van den Boorn et al.   Pigment Cell & Melanoma Research

Peroxiredoxin 6: A Bifunctional Enzyme with Glutathione Peroxidase and Phospholipase A2 Activities

(2010) Aron B. Fisher   ANTIOXIDANTS & REDOX SIGNALING

Vitiligo, reactive oxygen species and T-cells

(2010) Steven J. Glassman   CLINICAL SCIENCE

Transcriptional Upregulation of Nrf2-Dependent Phase II Detoxification Genes in the Involved Epidermis of Vitiligo Vulgaris

(2010) Vivek T. Natarajan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Depigmentation therapies for normal skin in vitiligo universalis

(2010) K.M. AlGhamdi et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Monobenzyl Ether of Hydroquinone and 4-Tertiary Butyl Phenol Activate Markedly Different Physiological Responses in Melanocytes: Relevance to Skin Depigmentation

(2009) Vidhya Hariharan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY