Minocycline: far beyond an antibiotic

Increases in β-amyloid protein in the hippocampus caused by diabetic metabolic disorder are blocked by minocycline through inhibition of NF-κB pathway activation

(2014) Zhiyou Cai et al.   Pharmacological Reports

Minocycline reduces plaque size in diet induced atherosclerosis via p27Kip1

(2011) Khurrum Shahzad et al.   ATHEROSCLEROSIS

Minocycline inhibits the growth of glioma by inducing autophagy

(2011) Wei-Ting Liu et al.   Autophagy

The association of minocycline and the probiotic Escherichia coli Nissle 1917 results in an additive beneficial effect in a DSS model of reactivated colitis in mice

(2011) Natividad Garrido-Mesa et al.   BIOCHEMICAL PHARMACOLOGY

Minocycline reduces glioma expansion and invasion by attenuating microglial MT1-MMP expression

(2011) D.S. Markovic et al.   BRAIN BEHAVIOR AND IMMUNITY

Matrix metalloproteinases in tumorigenesis: an evolving paradigm

(2011) Hui Hua et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Neural circuit architecture defects in a Drosophila model of Fragile X syndrome are alleviated by minocycline treatment and genetic removal of matrix metalloproteinase

(2011) S. S. Siller et al.   Disease Models & Mechanisms

Minocycline attenuates ischemia-induced ventricular arrhythmias in rats

(2011) Xiaorong Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Minocycline attenuates the development of diabetic neuropathic pain: Possible anti-inflammatory and anti-oxidant mechanisms

(2011) Kavita Pabreja et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Matrix Metalloproteinase Inhibitors Attenuate Neuroinflammation Following Focal Cerebral Ischemia in Mice

(2011) Cheol Hong Park et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Minocycline treatment for HIV-associated cognitive impairment: Results from a randomized trial

(2011) N. Sacktor et al.   NEUROLOGY

Minocycline injection in the ventral posterolateral thalamus reverses microglial reactivity and thermal hyperalgesia secondary to sciatic neuropathy

(2011) Brian W. LeBlanc et al.   NEUROSCIENCE LETTERS

Post-injury administration of minocycline: An effective treatment for nerve-injury induced neuropathic pain

(2011) Xiao-Peng Mei et al.   NEUROSCIENCE RESEARCH

The road forward: The scientific basis for tetracycline treatment of arthritic disorders

(2011) Robert A. Greenwald   PHARMACOLOGICAL RESEARCH

Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs

(2011) Rauno Joks et al.   PHARMACOLOGICAL RESEARCH

Minocycline Inhibition of Monocyte Activation Correlates with Neuronal Protection in SIV NeuroAIDS

(2011) Jennifer H. Campbell et al.   PLoS One

Neuronal and microglial mechanisms of neuropathic pain

(2011) Min Zhuo et al.   Molecular Brain

Minocycline fails to modulate cerebrospinal fluid HIV infection or immune activation in chronic untreated HIV-1 infection: results of a pilot study

(2011) Emily L Ho et al.   AIDS Research and Therapy

Improving Outcomes of Neuroprotection by Minocycline

(2010) Mengzhou Xue et al.   AMERICAN JOURNAL OF PATHOLOGY

Tetracyclines: a pleitropic family of compounds with promising therapeutic properties. Review of the literature

(2010) Michael O. Griffin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Open-label add-on treatment trial of minocycline in fragile X syndrome

(2010) Carlo Paribello et al.   BMC Neurology

The influence of tetracyclines on T cell activation

(2010) M. KLOPPENBURG et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Minocycline protects against myocardial ischemia and reperfusion injury by inhibiting high mobility group box 1 protein in rats

(2010) Xiaorong Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Tetracycline-mediated IgE isotype-specific suppression of ongoing human and murine IgE responses in vivo and murine memory IgE responses induced in vitro

(2010) R. Joks et al.   INTERNATIONAL IMMUNOLOGY

Minocycline Protects Cardiac Myocytes Against Simulated Ischemia–Reperfusion Injury by Inhibiting Poly(ADP-ribose) Polymerase-1

(2010) Rong Tao et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Clinical and Biochemical Efficacy of Minocycline in Nonsurgical Periodontal Therapy: A Randomized Controlled Pilot Study

(2010) Cansu Basegmez et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Minocycline Attenuates HIV Infection and Reactivation by Suppressing Cellular Activation in Human CD4+T Cells

(2010) Gregory L. Szeto et al.   JOURNAL OF INFECTIOUS DISEASES

Early-Stage Inflammation and Experimental Therapy in Transgenic Models of the Alzheimer-Like Amyloid Pathology

(2010) A.C. Cuello et al.   Neurodegenerative Diseases

The intestinal anti-inflammatory effect of minocycline in experimental colitis involves both its immunomodulatory and antimicrobial properties

(2010) Natividad Garrido-Mesa et al.   PHARMACOLOGICAL RESEARCH

Chemically modified non-antimicrobial tetracyclines are multifunctional drugs against advanced cancers☆

(2010) Bal L. Lokeshwar   PHARMACOLOGICAL RESEARCH

Proton Magnetic Resonance Spectroscopy Reveals Neuroprotection by Oral Minocycline in a Nonhuman Primate Model of Accelerated NeuroAIDS

(2010) Eva-Maria Ratai et al.   PLoS One

Tetracyclines Modulate Protease-Activated Receptor 2-Mediated Proinflammatory Reactions in Epidermal Keratinocytes

(2009) C. Ishikawa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Minocycline attenuates 5-fluorouracil-induced small intestinal mucositis in mouse model

(2009) Tien-Yu Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Microglia and neuropathic pain

(2009) Kazuhide Inoue et al.   GLIA

Current topical and systemic approaches to treatment of rosacea

(2009) HC Korting et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Glatiramer acetate in combination with minocycline in patients with relapsing—remitting multiple sclerosis: results of a Canadian, multicenter, double-blind, placebo-controlled trial

(2009) LM Metz et al.   Multiple Sclerosis Journal

Minocycline attenuates experimental colitis in mice by blocking expression of inducible nitric oxide synthase and matrix metalloproteinases

(2009) Tien-Yu Huang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Minocycline treatment results in reduced oral steroid requirements in adult asthma

(2008) Ammar Daoud et al.   ALLERGY AND ASTHMA PROCEEDINGS

The Combined Effects of Celecoxib and Minocycline Hydrochloride on Inhibiting the Osseous Metastasis of Breast Cancer in Nude Mice

(2008) Guangfeng Niu et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

(2008) Martin Andrassy et al.   CIRCULATION

Drugs Used to Treat Parkinsons Disease, Present Status and Future Directions

(2008) Omar Abdel-Salam   CNS & Neurological Disorders-Drug Targets

Combined treatment with atorvastatin and minocycline suppresses severity of EAE

(2008) Ilaria Luccarini et al.   EXPERIMENTAL NEUROLOGY

Clinical use of E. coli Nissle 1917 in inflammatory bowel disease

(2008) Michael Schultz   INFLAMMATORY BOWEL DISEASES

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia

(2008) Christopher J Henry et al.   Journal of Neuroinflammation

Mechanisms of minocycline-induced suppression of simian immunodeficiency virus encephalitis: inhibition of apoptosis signal-regulating kinase 1

(2008) Susan C Follstaedt et al.   JOURNAL OF NEUROVIROLOGY

Cardiac Uptake of Minocycline and Mechanisms for In Vivo Cardioprotection

(2008) Diego Romero-Perez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

Limited minocycline neuroprotection after balloon-compression spinal cord injury in the rat

(2008) Kamila Saganová et al.   NEUROSCIENCE LETTERS

Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases

(2007) Kristina Stefansson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes

(2005) Scott R Macfarlane et al.   BRITISH JOURNAL OF PHARMACOLOGY