Hydrogel-based colorectal cancer organoid co-culture models

Brain Organoids: A Promising Living Biobank Resource for Neuroscience Research

(2020) Shuang Li et al.   BIOPRESERVATION AND BIOBANKING

Efficacy of primary liver organoid culture from different stages of non-alcoholic steatohepatitis (NASH) mouse model

(2020) Mohamed Elbadawy et al.   BIOMATERIALS

Cancer-associated fibroblasts in gastrointestinal cancer

(2019) Hiroki Kobayashi et al.   Nature Reviews Gastroenterology & Hepatology

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

(2019) Oded Kopper et al.   NATURE MEDICINE

Oral mucosal organoids as a potential platform for personalized cancer therapy

(2019) Else Driehuis et al.   Cancer Discovery

Integrins, CAFs and Mechanical Forces in the Progression of Cancer

(2019) Imjoo Jang et al.   Cancers

Mechanically and chemically defined hydrogel matrices for patient-derived colorectal tumor organoid culture

(2019) Shengyong Ng et al.   BIOMATERIALS

Establishment of a novel experimental model for muscle‐invasive bladder cancer using a dog bladder cancer organoid culture

(2019) Mohamed Elbadawy et al.   CANCER SCIENCE

Cancer modeling meets human organoid technology

(2019) David Tuveson et al.   SCIENCE

Colorectal cancer

(2019) Evelien Dekker et al.   LANCET

Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression

(2018) Takashi Seino et al.   Cell Stem Cell

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

HGF-mediated crosstalk between cancer-associated fibroblasts and MET-unamplified gastric cancer cells activates coordinated tumorigenesis and metastasis

(2018) Xusheng Ding et al.   Cell Death & Disease

A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening

(2018) Helen H.N. Yan et al.   Cell Stem Cell

Constructing and Deconstructing Cancers using Human Pluripotent Stem Cells and Organoids

(2018) Ryan C. Smith et al.   Cell Stem Cell

Mesenchymal Cells in Colon Cancer

(2017) Vasiliki Koliaraki et al.   GASTROENTEROLOGY

Human colorectal cancer progression correlates with LOX-induced ECM stiffening

(2017) Bo Wei et al.   International Journal of Biological Sciences

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

(2017) Daniel Öhlund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cancer-associated fibroblasts enhance metastatic potential of lung cancer cells through IL-6/STAT3 signaling pathway

(2017) Limin Wang et al.   Oncotarget

A 3D in vitro model of patient-derived prostate cancer xenograft for controlled interrogation of in vivo tumor-stromal interactions

(2016) Eliza L.S. Fong et al.   BIOMATERIALS

Designer matrices for intestinal stem cell and organoid culture

(2016) Nikolce Gjorevski et al.   NATURE

Carcinoma-associated fibroblasts affect sensitivity to oxaliplatin and 5FU in colorectal cancer cells

(2016) Samuel Gonçalves-Ribeiro et al.   Oncotarget

Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling

(2016) Eunice Yuen Ting Lau et al.   Cell Reports

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Impact of the spheroid model complexity on drug response

(2015) Oliver Ingo Hoffmann et al.   JOURNAL OF BIOTECHNOLOGY

Stromal gene expression defines poor-prognosis subtypes in colorectal cancer

(2015) Alexandre Calon et al.   NATURE GENETICS

Stromal contribution to the colorectal cancer transcriptome

(2015) Claudio Isella et al.   NATURE GENETICS

Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling

(2015) E Sanchez-Lopez et al.   ONCOGENE

Multilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures

(2015) Brian J. Engel et al.   Advanced Healthcare Materials

Bioengineered 3D Brain Tumor Model To Elucidate the Effects of Matrix Stiffness on Glioblastoma Cell Behavior Using PEG-Based Hydrogels

(2014) Christine Wang et al.   MOLECULAR PHARMACEUTICS

TGF-beta in CAF-mediated tumor growth and metastasis

(2014) A. Calon et al.   SEMINARS IN CANCER BIOLOGY

Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling

(2014) Wan-Jiun Chen et al.   Nature Communications

Role of the Adjacent Stroma Cells in Prostate Cancer Development and Progression: Synergy between TGF-βand IGF Signaling

(2014) Chung Lee et al.   Biomed Research International

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Hyaluronan in intestinal homeostasis and inflammation: implications for fibrosis

(2011) Carol A. de la Motte   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The variant call format and VCFtools

(2011) P. Danecek et al.   BIOINFORMATICS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine

(2011) Glenn D. Prestwich   JOURNAL OF CONTROLLED RELEASE

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Cancer-Associated Fibroblasts Derived from EGFR-TKI-Resistant Tumors Reverse EGFR Pathway Inhibition by EGFR-TKIs

(2010) S. R. Mink et al.   MOLECULAR CANCER RESEARCH

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Effect of Gentamicin on Growth and Differentiation of Human Mesenchymal Stem Cells

(2008) Harumi Kagiwada et al.   Journal of Toxicologic Pathology