Role of the Adjacent Stroma Cells in Prostate Cancer Development and Progression: Synergy between TGF-βand IGF Signaling

Stromal-epithelial interactions in early neoplasia

(2017) Alvin Y. Liu et al.   Cancer Biomarkers

High circulating estrogens and selective expression of ERβ in prostate tumors of Americans: implications for racial disparity of prostate cancer

(2013) Zakaria Y. Abd Elmageed et al.   CARCINOGENESIS

Targeting the Insulin Growth Factor Receptor 1

(2012) Fernanda I. Arnaldez et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Loss of TGF-  Responsiveness in Prostate Stromal Cells Alters Chemokine Levels and Facilitates the Development of Mixed Osteoblastic/Osteolytic Bone Lesions

(2012) X. Li et al.   MOLECULAR CANCER RESEARCH

Human Epithelial Basal Cells Are Cells of Origin of Prostate Cancer, Independent of CD133 Status

(2012) Renea A. Taylor et al.   STEM CELLS

Understanding the role of stromal fibroblasts in cancer progression

(2012) Manisha Tripathi et al.   Cell Adhesion & Migration

Diagnosis of Prostate Cancer Using Differentially Expressed Genes in Stroma

(2011) Z. Jia et al.   CANCER RESEARCH

Role for Stromal Heterogeneity in Prostate Tumorigenesis

(2011) M. A. Kiskowski et al.   CANCER RESEARCH

Altered TGF-β Signaling in a Subpopulation of Human Stromal Cells Promotes Prostatic Carcinogenesis

(2011) Omar E. Franco et al.   CANCER RESEARCH

Non-Smad signaling pathways

(2011) Yabing Mu et al.   CELL AND TISSUE RESEARCH

Antibody Targeting of TGF-β in Cancer Patients

(2011) Scott Lonning et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The functional role of reactive stroma in benign prostatic hyperplasia

(2011) Isaiah G. Schauer et al.   DIFFERENTIATION

Estrogens Promote Invasion of Prostate Cancer Cells in a Paracrine Manner through Up-Regulation of Matrix Metalloproteinase 2 in Prostatic Stromal Cells

(2011) Lin Yu et al.   ENDOCRINOLOGY

Advanced-glycation-end-product-cholesterol-aggregated-protein accelerates the proliferation of mesangial cells mediated by transforming-growth-factor-beta 1 receptors and the ERK-MAPK pathway

(2011) Yasushi Hirasawa et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Negative Androgen-Response Elements Mediate Androgen-Dependent Transcriptional Inhibition of TGF- 1 and CDK2 Promoters in the Prostate Gland

(2011) W. Qi et al.   JOURNAL OF ANDROLOGY

Non-Smad Transforming Growth Factor-β Signaling Regulated by Focal Adhesion Kinase Binding the p85 Subunit of Phosphatidylinositol 3-Kinase

(2011) Min Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin-like growth factor 1 stimulation of androgen receptor activity requires β1A integrins

(2011) Aejaz Sayeed et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Unbalanced metabolism of endogenous estrogens in the etiology and prevention of human cancer

(2011) Ercole L. Cavalieri et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Transcription Factors Snail and Slug Activate the Transforming Growth Factor-Beta Signaling Pathway in Breast Cancer

(2011) Archana Dhasarathy et al.   PLoS One

Emergence of the Phosphoinositide 3-Kinase-Akt- Mammalian Target of Rapamycin Axis in Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition

(2010) Samy Lamouille et al.   CELLS TISSUES ORGANS

Role of SMAD and Non-SMAD Signals in the Development of Th17 and Regulatory T Cells

(2010) L. Lu et al.   JOURNAL OF IMMUNOLOGY

Overexpression of Transforming Growth Factor β1 in Malignant Prostate Cells is Partly Caused by a Runaway of TGF-β1 Auto-induction Mediated Through a Defective Recruitment of Protein Phosphatase 2A by TGF-β Type I Receptor

(2010) Nengwang Yu et al.   UROLOGY

Phthoxazolin A inhibits prostate cancer growth by modulating tumor-stromal cell interactions

(2009) Manabu Kawada et al.   CANCER SCIENCE

17β-Estradiol at Low Concentrations Acts through Distinct Pathways in Normal Versus Benign Prostatic Hyperplasia-Derived Prostate Stromal Cells

(2009) Irwin I. Park et al.   ENDOCRINOLOGY

The Sonic Hedgehog pathway stimulates prostate tumor growth by paracrine signaling and recapitulates embryonic gene expression in tumor myofibroblasts

(2009) A Shaw et al.   ONCOGENE

Transforming growth factor-β signaling in epithelial-mesenchymal transition and progression of cancer

(2009) Kohei MIYAZONO   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

New regulatory mechanisms of TGF-β receptor function

(2009) Jong Seok Kang et al.   TRENDS IN CELL BIOLOGY

Stroma–epithelium crosstalk in prostate cancer

(2008) Yi-Nong Niu et al.   ASIAN JOURNAL OF ANDROLOGY

Stromal myofibroblasts are drivers of invasive cancer growth

(2008) Olivier De Wever et al.   INTERNATIONAL JOURNAL OF CANCER

Implications of insulin-like growth factor-I for prostate cancer therapies

(2008) Satoko Kojima et al.   INTERNATIONAL JOURNAL OF UROLOGY

Biological functions and clinical implications of oestrogen receptors alfa and beta in epithelial tissues

(2008) A. Morani et al.   JOURNAL OF INTERNAL MEDICINE

TGF-β1 targets the GSK-3β/β-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts

(2008) F CARACI et al.   PHARMACOLOGICAL RESEARCH

TGF-β signaling and androgen receptor status determine apoptotic cross-talk in human prostate cancer cells

(2007) Meng-Lei Zhu et al.   PROSTATE