Computational simulation of formin-mediated actin polymerization predicts homologue-dependent mechanosensitivity

Multisite Phosphorylation Modulates the T Cell Receptor ζ -Chain Potency but not the Switchlike Response

(2016) Himadri Mukhopadhyay et al.   BIOPHYSICAL JOURNAL

The inner workings of stress fibers − from contractile machinery to focal adhesions and back

(2016) Ariel Livne et al.   JOURNAL OF CELL SCIENCE

Phase separation of signaling molecules promotes T cell receptor signal transduction

(2016) Xiaolei Su et al.   SCIENCE

Computational model of polarized actin cables and cytokinetic actin ring formation in budding yeast

(2015) Haosu Tang et al.   Cytoskeleton

An updated look at actin dynamics in filopodia

(2015) Natascha Leijnse et al.   Cytoskeleton

In vivo quantitative analysis of Talin turnover in response to force

(2015) Guðlaug Katrín Hákonardóttir et al.   MOLECULAR BIOLOGY OF THE CELL

Intrinsically disordered proteins in cellular signalling and regulation

(2015) Peter E. Wright et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim

(2015) Xiaowei Shao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Talin determines the nanoscale architecture of focal adhesions

(2015) Jaron Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Network Morphology and Tension Buildup in a 3D Model of Cytokinetic Ring Assembly

(2014) Tamara C. Bidone et al.   BIOPHYSICAL JOURNAL

A cooperative jack model of random coil-to-elongation transition of the FH1 domain by profilin binding explains formin motor behavior in actin polymerization

(2014) Chen Zhao et al.   FEBS LETTERS

Appreciating force and shape — the rise of mechanotransduction in cell biology

(2014) Thomas Iskratsch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Actin Dynamics, Architecture, and Mechanics in Cell Motility

(2014) Laurent Blanchoin et al.   PHYSIOLOGICAL REVIEWS

A tethered delivery mechanism explains the catalytic action of a microtubule polymerase

(2014) Pelin Ayaz et al.   eLife

Mechanochemitry: A Molecular Biomechanics View of Mechanosensing

(2013) Cheng Zhu   ANNALS OF BIOMEDICAL ENGINEERING

How filopodia pull: What we know about the mechanics and dynamics of filopodia

(2013) Thomas Bornschlögl   Cytoskeleton

FHOD1 Is Needed for Directed Forces and Adhesion Maturation during Cell Spreading and Migration

(2013) Thomas Iskratsch et al.   DEVELOPMENTAL CELL

Integrating actin dynamics, mechanotransduction and integrin activation: The multiple functions of actin binding proteins in focal adhesions

(2013) Corina Ciobanasu et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Mechanotransduction down to individual actin filaments

(2013) Guillaume Romet-Lemonne et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Analysis of the local organization and dynamics of cellular actin networks

(2013) Weiwei Luo et al.   JOURNAL OF CELL BIOLOGY

Formins at a glance

(2013) Dennis Breitsprecher et al.   JOURNAL OF CELL SCIENCE

Tension modulates actin filament polymerization mediated by formin and profilin

(2013) N. Courtemanche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formin mDia1 senses and generates mechanical forces on actin filaments

(2013) Antoine Jégou et al.   Nature Communications

How Random are Intrinsically Disordered Proteins? A Small Angle Scattering Perspective

(2012) Veronique Receveur-Brechot et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Determinants of Formin Homology 1 (FH1) Domain Function in Actin Filament Elongation by Formins

(2012) Naomi Courtemanche et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Actin cortex mechanics and cellular morphogenesis

(2012) Guillaume Salbreux et al.   TRENDS IN CELL BIOLOGY

Nucleation and Decay Initiation Are the Stiffness-Sensitive Phases of Focal Adhesion Maturation

(2011) Sam Walcott et al.   BIOPHYSICAL JOURNAL

Molecular mechanism of Ena/VASP-mediated actin-filament elongation

(2011) Dennis Breitsprecher et al.   EMBO JOURNAL

Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

(2011) Kimihide Hayakawa et al.   JOURNAL OF CELL BIOLOGY

Model of myosin node aggregation into a contractile ring: the effect of local alignment

(2011) Nikola Ojkic et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Regulation of biochemical reaction rates by flexible tethers

(2011) Daniel Reeves et al.   PHYSICAL REVIEW E

Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information

(2011) M. C. Good et al.   SCIENCE

Monte Carlo Analysis of Neck Linker Extension in Kinesin Molecular Motors

(2010) Matthew L. Kutys et al.   PLoS Computational Biology

Detailed Simulations of Cell Biology with Smoldyn 2.1

(2010) Steven S. Andrews et al.   PLoS Computational Biology

Biochemistry on a Leash: The Roles of Tether Length and Geometry in Signal Integration Proteins

(2009) David Van Valen et al.   BIOPHYSICAL JOURNAL

Energetic Requirements for Processive Elongation of Actin Filaments by FH1FH2-formins

(2009) Aditya S. Paul et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Origins and Evolution of the Formin Multigene Family That Is Involved in the Formation of Actin Filaments

(2008) D. Chalkia et al.   MOLECULAR BIOLOGY AND EVOLUTION

mDia2 Induces the Actin Scaffold for the Contractile Ring and Stabilizes Its Position during Cytokinesis in NIH 3T3 Cells

(2008) Sadanori Watanabe et al.   MOLECULAR BIOLOGY OF THE CELL

The Role of the FH1 Domain and Profilin in Formin-Mediated Actin-Filament Elongation and Nucleation

(2007) Aditya Paul et al.   CURRENT BIOLOGY