The inner workings of stress fibers − from contractile machinery to focal adhesions and back

Focal adhesions, stress fibers and mechanical tension

(2016) Keith Burridge et al.   EXPERIMENTAL CELL RESEARCH

A biomechanical perspective on stress fiber structure and function

(2015) Elena Kassianidou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structured illumination microscopy reveals focal adhesions are composed of linear subunits

(2015) Shiqiong Hu et al.   Cytoskeleton

Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions

(2015) Lindsay B. Case et al.   NATURE CELL BIOLOGY

Cellular chirality arising from the self-organization of the actin cytoskeleton

(2015) Yee Han Tee et al.   NATURE CELL BIOLOGY

Inverted formin 2 in focal adhesions promotes dorsal stress fiber and fibrillar adhesion formation to drive extracellular matrix assembly

(2015) Colleen T. Skau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Model-based Traction Force Microscopy Reveals Differential Tension in Cellular Actin Bundles

(2015) Jérôme R. D. Soiné et al.   PLoS Computational Biology

Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly

(2015) Sari Tojkander et al.   eLife

Geometry Regulates Traction Stresses in Adherent Cells

(2014) Patrick W. Oakes et al.   BIOPHYSICAL JOURNAL

Fascin Plays a Role in Stress Fiber Organization and Focal Adhesion Disassembly

(2014) Nadia Elkhatib et al.   CURRENT BIOLOGY

A contractile and counterbalancing adhesion system controls the 3D shape of crawling cells

(2014) Dylan T. Burnette et al.   JOURNAL OF CELL BIOLOGY

Palladin promotes assembly of non-contractile dorsal stress fibers through VASP recruitment

(2014) G. Gateva et al.   JOURNAL OF CELL SCIENCE

Tight coupling between nucleus and cell migration through the perinuclear actin cap

(2014) D.-H. Kim et al.   JOURNAL OF CELL SCIENCE

Forces driving epithelial wound healing

(2014) Agustí Brugués et al.   Nature Physics

The integrin adhesome: from genes and proteins to human disease

(2014) Sabina E. Winograd-Katz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A mechanical-biochemical feedback loop regulates remodeling in the actin cytoskeleton

(2014) Matthew R. Stachowiak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix

(2014) R. J. Petrie et al.   SCIENCE

LIM proteins in actin cytoskeleton mechanoresponse

(2014) M.A. Smith et al.   TRENDS IN CELL BIOLOGY

Cell reorientation under cyclic stretching

(2014) Ariel Livne et al.   Nature Communications

The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion

(2014) Or-Yam Revach et al.   Cell Adhesion & Migration

The tension mounts: Stress fibers as force-generating mechanotransducers

(2013) Keith Burridge et al.   JOURNAL OF CELL BIOLOGY

Differential Effect of Actomyosin Relaxation on the Dynamic Properties of Focal Adhesion Proteins

(2013) Irena Lavelin et al.   PLoS One

Actin stress fibre subtypes in mesenchymal-migrating cells

(2013) T. Vallenius   Open Biology

Myosin motors fragment and compact membrane-bound actin filaments

(2013) Sven K Vogel et al.   eLife

The constant beat: cardiomyocytes adapt their forces by equal contraction upon environmental stiffening

(2013) N. Hersch et al.   Biology Open

Lateral Communication between Stress Fiber Sarcomeres Facilitates a Local Remodeling Response

(2012) Laura M. Chapin et al.   BIOPHYSICAL JOURNAL

Actin Depolymerization Drives Actomyosin Ring Contraction during Budding Yeast Cytokinesis

(2012) Inês Mendes Pinto et al.   DEVELOPMENTAL CELL

Actin stress fibers - assembly, dynamics and biological roles

(2012) S. Tojkander et al.   JOURNAL OF CELL SCIENCE

Dual-objective STORM reveals three-dimensional filament organization in the actin cytoskeleton

(2012) Ke Xu et al.   NATURE METHODS

Cells test substrate rigidity by local contractions on submicrometer pillars

(2012) S. Ghassemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

(2012) L. Trichet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin cap associated focal adhesions and their distinct role in cellular mechanosensing

(2012) Dong-Hwee Kim et al.   Scientific Reports

Spatiotemporal Constraints on the Force-Dependent Growth of Focal Adhesions

(2011) Jonathan Stricker et al.   BIOPHYSICAL JOURNAL

A Novel Method for Measuring Tension Generated in Stress Fibers by Applying External Forces

(2011) Shukei Sugita et al.   BIOPHYSICAL JOURNAL

A Molecular Pathway for Myosin II Recruitment to Stress Fibers

(2011) Sari Tojkander et al.   CURRENT BIOLOGY

Sarcomere length fluctuations and flow in capillary endothelial cells

(2011) Robert J. Russell et al.   Cytoskeleton

Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins

(2011) Herbert B Schiller et al.   EMBO REPORTS

Mechanism of Actin Filament Bundling by Fascin

(2011) Silvia Jansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heterogeneous response of traction force at focal adhesions of vascular smooth muscle cells subjected to macroscopic stretch on a micropillar substrate

(2011) Kazuaki Nagayama et al.   JOURNAL OF BIOMECHANICS

Automated segmentation of electron tomograms for a quantitative description of actin filament networks

(2011) Alexander Rigort et al.   JOURNAL OF STRUCTURAL BIOLOGY

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

(2011) Jean-Cheng Kuo et al.   NATURE CELL BIOLOGY

A role for actin arcs in the leading-edge advance of migrating cells

(2011) Dylan T. Burnette et al.   NATURE CELL BIOLOGY

Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing

(2011) Masha Prager-Khoutorsky et al.   NATURE CELL BIOLOGY

Proteomic Analysis of Integrin Adhesion Complexes

(2011) A. Byron et al.   Science Signaling

Molecular Architecture and Function of Matrix Adhesions

(2011) B. Geiger et al.   Cold Spring Harbor Perspectives in Biology

Cytoskeletal Cross-linking and Bundling in Motor-Independent Contraction

(2010) Sean X. Sun et al.   CURRENT BIOLOGY

Unconventional Processive Mechanics of Non-muscle Myosin IIB

(2010) Melanie F. Norstrom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estimation of single stress fiber stiffness in cultured aortic smooth muscle cells under relaxed and contracted states: Its relation to dynamic rearrangement of stress fibers

(2010) Kazuaki Nagayama et al.   JOURNAL OF BIOMECHANICS

The switchable integrin adhesome

(2010) R. Zaidel-Bar et al.   JOURNAL OF CELL SCIENCE

Platelet retraction force measurements using flexible post force sensors

(2010) Xin M. Liang et al.   LAB ON A CHIP

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography

(2010) Israel Patla et al.   NATURE CELL BIOLOGY

Optimal matrix rigidity for stress-fibre polarization in stem cells

(2010) A. Zemel et al.   Nature Physics

Sarcomere Mechanics in Capillary Endothelial Cells

(2009) Robert J. Russell et al.   BIOPHYSICAL JOURNAL

Live Cells Exert 3-Dimensional Traction Forces on Their Substrata

(2009) Sung Sik Hur et al.   Cellular and Molecular Bioengineering

The integrin adhesion complex changes its composition and function during morphogenesis of an epithelium

(2009) I. Delon et al.   JOURNAL OF CELL SCIENCE

Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization

(2009) J. Colombelli et al.   JOURNAL OF CELL SCIENCE

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanical Properties of Actin Stress Fibers in Living Cells

(2008) Lan Lu et al.   BIOPHYSICAL JOURNAL

Cell motility through plasma membrane blebbing

(2008) Oliver T. Fackler et al.   JOURNAL OF CELL BIOLOGY

Mechanical forces facilitate actin polymerization at focal adhesions in a zyxin-dependent manner

(2008) H. Hirata et al.   JOURNAL OF CELL SCIENCE

Mechanisms of actin stress fibre assembly

(2008) P. NAUMANEN et al.   JOURNAL OF MICROSCOPY

Mechanism of shape determination in motile cells

(2008) Kinneret Keren et al.   NATURE

Filopodia: molecular architecture and cellular functions

(2008) Pieta K. Mattila et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Environmental sensing through focal adhesions

(2008) Benjamin Geiger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Kinetics of stress fibers

(2008) Matthew R Stachowiak et al.   NEW JOURNAL OF PHYSICS

High Resolution Traction Force Microscopy Based on Experimental and Computational Advances

(2007) Benedikt Sabass et al.   BIOPHYSICAL JOURNAL