Identification of Potential Drug Targets in Helicobacter pylori Using In Silico Subtractive Proteomics Approaches and Their Possible Inhibition through Drug Repurposing

Novel and potent inhibitors for dihydropteroate synthase of Helicobacter pylori

(2020) Sri Harsha Satuluri et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Helicobacter pylori: A Review of Current Diagnostic and Management Strategies

(2020) Bernardo Guevara et al.   DIGESTIVE DISEASES AND SCIENCES

In Silico Subtractive Proteomics Approach for Identification of Potential Drug Targets in Staphylococcus saprophyticus

(2020) Farah Shahid et al.   International Journal of Environmental Research and Public Health

Genome Subtraction and Comparison for the Identification of Novel Drug Targets against Mycobacterium avium subsp. hominissuis

(2020) Reaz Uddin et al.   Pathogens

Drug Repurposing for the Treatment of Bacterial and Fungal Infections

(2019) Andrea Miró-Canturri et al.   Frontiers in Microbiology

Eradication rate of Helicobacter pylori reinfection in Korea: A retrospective study

(2019) Young Kwon Choi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Characterization of antimicrobial activity of three Lactobacillus plantarum strains isolated from Chinese traditional dairy food

(2019) Chang‐Hui Hu et al.   Food Science & Nutrition

Cefuroxime, levofloxacin, esomeprazole, and bismuth as first-line therapy for eradicating Helicobacter pylori in patients allergic to penicillin

(2019) Zhiqiang Song et al.   BMC GASTROENTEROLOGY

Review: Treatment of Helicobacter pylori Infection 2019

(2019) Anthony O'Connor et al.   HELICOBACTER

KEGG Mapper for inferring cellular functions from protein sequences

(2019) Minoru Kanehisa et al.   PROTEIN SCIENCE

Organic acids as antimicrobial food agents: applications and microbial productions

(2019) Hasan Bugra Coban   BIOPROCESS AND BIOSYSTEMS ENGINEERING

The global preclinical antibacterial pipeline

(2019) Ursula Theuretzbacher et al.   NATURE REVIEWS MICROBIOLOGY

Antibacterial Activity of Some Flavonoids and Organic Acids Widely Distributed in Plants

(2019) Artur Adamczak et al.   Journal of Clinical Medicine

Prioritization of potential drug targets against P. aeruginosa by core proteomic analysis using computational subtractive genomics and Protein-Protein interaction network

(2018) Reaz Uddin et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Prevalence of antibiotic resistance in Helicobacter pylori : a systematic review and meta-analysis in World Health Organization regions

(2018) Alessia Savoldi et al.   GASTROENTEROLOGY

A Comparative Study on the Effects of Quinic Acid and Shikimic Acid on Cellular Functions of Staphylococcus aureus

(2018) JINRONG BAI et al.   JOURNAL OF FOOD PROTECTION

Subtractive genome analysis for in silico identification and characterization of novel drug targets in Streptococcus pneumonia strain JJA

(2018) Abdul Wadood et al.   MICROBIAL PATHOGENESIS

An in silico study: Novel targets for potential drug and vaccine design against drug resistant H. pylori

(2018) Chiranjeevi Pasala et al.   MICROBIAL PATHOGENESIS

In Vitro Inhibition of Helicobacter pylori Growth by Redox Cycling Phenylaminojuglones

(2018) Julio Benites et al.   Oxidative Medicine and Cellular Longevity

Subtractive proteomics to identify novel drug targets and reverse vaccinology for the development of chimeric vaccine against Acinetobacter baumannii

(2018) Vandana Solanki et al.   Scientific Reports

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

An integrative, multi-omics approach towards the prioritization of Klebsiella pneumoniae drug targets

(2018) Pablo Ivan Pereira Ramos et al.   Scientific Reports

New approach for understanding genome variations in KEGG

(2018) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

PubChem 2019 update: improved access to chemical data

(2018) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

In vitro and in vivo Inhibitory Activity of NADPH Against the AmpC BER Class C β-Lactamase

(2018) Jung-Hyun Na et al.   Frontiers in Cellular and Infection Microbiology

Targeting the β-clamp in Helicobacter pylori with FDA-approved drugs reveals micromolar inhibition by diflunisal

(2017) Preeti Pandey et al.   FEBS LETTERS

Survival of Helicobacter pylori in gastric acidic territory

(2017) Shamshul Ansari et al.   HELICOBACTER

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

An in silico strategy for identification of novel drug targets against Plasmodium falciparum

(2017) Subhashree Rout et al.   PARASITOLOGY RESEARCH

Helicobacter pylori: past, current and future treatment strategies with gastroretentive drug delivery systems

(2016) Anurag Verma et al.   JOURNAL OF DRUG TARGETING

Composition, structure and function of theHelicobacter pylori cagpathogenicity island encoded type IV secretion system

(2015) Steffen Backert et al.   Future Microbiology

Novel Drug Targets for Food-Borne PathogenCampylobacter jejuni: An Integrated Subtractive Genomics and Comparative Metabolic Pathway Study

(2015) Kusum Mehla et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Targeting DnaN for tuberculosis therapy using novel griselimycins

(2015) A. Kling et al.   SCIENCE

Unraveling novel broad-spectrum antibacterial targets in food and waterborne pathogens using comparative genomics and protein interaction network analysis

(2014) Ankush Jadhav et al.   INFECTION GENETICS AND EVOLUTION

tRNAs as Antibiotic Targets

(2014) Shaileja Chopra et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antibiotics induce redox-related physiological alterations as part of their lethality

(2014) D. J. Dwyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibiotic drugs targeting bacterial RNAs

(2014) Weiling Hong et al.   Acta Pharmaceutica Sinica B

Identification of Novel Drug Targets in HpB38, HpP12, HpG27, Hpshi470, HpSJM180 Strains of Helicobacter pylori : An In Silico Approach for Therapeutic Intervention

(2013) Nageswara Rao Reddy Neelapu et al.   CURRENT DRUG TARGETS

Putative drug and vaccine target protein identification using comparative genomic analysis of KEGG annotated metabolic pathways of Mycoplasma hyopneumoniae

(2013) Dereje Damte et al.   GENOMICS

Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function

(2013) Jungwook Kim et al.   NATURE

DEG 10, an update of the database of essential genes that includes both protein-coding genes and noncoding genomic elements: Table 1.

(2013) Hao Luo et al.   NUCLEIC ACIDS RESEARCH

Recent research on 3-phenyllactic acid, a broad-spectrum antimicrobial compound

(2012) Wanmeng Mu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

targetTB: A target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis

(2012) Karthik Raman et al.   BMC Systems Biology

Mycoplasma genitalium: A comparative genomics study of metabolic pathways for the identification of drug and vaccine targets

(2011) Azeem Mehmood Butt et al.   INFECTION GENETICS AND EVOLUTION

Antagonistic Activities of Lactobacilli against Helicobacter pylori Growth and Infection in Human Gastric Epithelial Cells

(2011) Xiaohua Chen et al.   JOURNAL OF FOOD SCIENCE

In silico quest for putative drug targets in Helicobacter pylori HPAG1: molecular modeling of candidate enzymes from lipopolysaccharide biosynthesis pathway

(2011) Munmun Sarkar et al.   JOURNAL OF MOLECULAR MODELING

Citric acid inhibits growth of Helicobacter pylori in vitro: a new strategy for eradication

(2011) Jan Zazgornik et al.   WIENER KLINISCHE WOCHENSCHRIFT

PSORTb 3.0: improved protein subcellular localization prediction with refined localization subcategories and predictive capabilities for all prokaryotes

(2010) Nancy Y. Yu et al.   BIOINFORMATICS

In silico subtractive genomics for target identification in human bacterial pathogens

(2010) Debmalya Barh et al.   DRUG DEVELOPMENT RESEARCH

Antibacterial activity of organic acids in aqueous extracts from pine needles (Pinus massoniana Lamb.)

(2010) Su Feng et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Antagonistic Activity of Spent Culture Supernatants of Lactic Acid Bacteria against Helicobacter Pylori Growth and Infection in Human Gastric Epithelial AGS Cells

(2009) Wen-Hsin Lin et al.   JOURNAL OF FOOD SCIENCE

The Role of UPF0157 in the Folding of M. tuberculosis Dephosphocoenzyme A Kinase and the Regulation of the Latter by CTP

(2009) Guneet Walia et al.   PLoS One

Growth inhibitory action of cranberry onHelicobacter pylori

(2008) Masashi Matsushima et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

DEG 5.0, a database of essential genes in both prokaryotes and eukaryotes

(2008) R. Zhang et al.   NUCLEIC ACIDS RESEARCH