- Home
- Publications
- Publication Search
- Publication Details
Title
tRNAs as Antibiotic Targets
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 16, Issue 1, Pages 321-349
Publisher
MDPI AG
Online
2014-12-26
DOI
10.3390/ijms16010321
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Antibiotics that affect the ribosome
- (2016) T. LAMBERT REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES
- The unique chemistry of benzoxaboroles: Current and emerging applications in biotechnology and therapeutic treatments
- (2014) C. Tony Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Tavaborole (AN-2690) for the treatment of onychomycosis of the toenail in adults
- (2014) Aditya K Gupta et al. Expert Review of Anti-Infective Therapy
- tRNA Modification Enzymes GidA and MnmE: Potential Role in Virulence of Bacterial Pathogens
- (2014) Daniel Shippy et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A real-time fluorescence polarization activity assay to screen for inhibitors of bacterial ribonuclease P
- (2014) Xin Liu et al. NUCLEIC ACIDS RESEARCH
- The general mode of translation inhibition by macrolide antibiotics
- (2014) Krishna Kannan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- tRNA gene diversity in the three domains of life
- (2014) Kosuke Fujishima et al. Frontiers in Genetics
- tRNAs as regulators of biological processes
- (2014) Medha Raina et al. Frontiers in Genetics
- ComparativeIn VitroActivities of GSK2251052, a Novel Boron-Containing Leucyl-tRNA Synthetase Inhibitor, against 916 Anaerobic Organisms
- (2013) Ellie J. C. Goldstein et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Phosphorylation of chloramphenicol by a recombinant protein Yhr2 from Streptomyces avermitilis MA4680
- (2013) Thangamani Rajesh et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Amythiamicin D and Related Thiopeptides as Inhibitors of the Bacterial Elongation Factor EF-Tu: Modification of the Amino Acid at Carbon Atom C2 of Ring C Dramatically Influences Activity
- (2013) Stefan Gross et al. ChemMedChem
- Aminoacyl-tRNA synthetases in medicine and disease
- (2013) Peng Yao et al. EMBO Molecular Medicine
- The Temperature Sensitivity of a Mutation in the Essential tRNA Modification Enzyme tRNA Methyltransferase D (TrmD)
- (2013) Isao Masuda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Magic Spot: A ppGpp Binding Site on E. coli RNA Polymerase Responsible for Regulation of Transcription Initiation
- (2013) Wilma Ross et al. MOLECULAR CELL
- Structural basis for the drug extrusion mechanism by a MATE multidrug transporter
- (2013) Yoshiki Tanaka et al. NATURE
- Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome
- (2013) E. Svidritskiy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Plant tumour biocontrol agent employs a tRNA-dependent mechanism to inhibit leucyl-tRNA synthetase
- (2013) Shaileja Chopra et al. Nature Communications
- Mechanism of tetracycline resistance by ribosomal protection protein Tet(O)
- (2013) Wen Li et al. Nature Communications
- Biosynthesis and Function of Posttranscriptional Modifications of Transfer RNAs
- (2012) Basma El Yacoubi et al. Annual Review of Genetics
- The Genetic Environment of thecfrGene and the Presence of Other Mechanisms Account for the Very High Linezolid Resistance of Staphylococcus epidermidis Isolate 426-3147L
- (2012) Jacqueline LaMarre et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Aminoacyl-tRNA Synthetase Inhibitors As Potent Antibacterials
- (2012) P.-C Lv et al. CURRENT MEDICINAL CHEMISTRY
- Structural insights into eukaryotic ribosomes and the initiation of translation
- (2012) Felix Voigts-Hoffmann et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- New therapeutic options for onychomycosis
- (2012) Aditya K Gupta et al. EXPERT OPINION ON PHARMACOTHERAPY
- Biosynthesis of Threonylcarbamoyl Adenosine (t6A), a Universal tRNA Nucleoside
- (2012) Christopher Deutsch et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chalcone–Benzoxaborole Hybrid Molecules as Potent Antitrypanosomal Agents
- (2012) Zhitao Qiao et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Antibiotic Thermorubin Inhibits Protein Synthesis by Binding to Inter-Subunit Bridge B2a of the Ribosome
- (2012) David Bulkley et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural basis for TetM-mediated tetracycline resistance
- (2012) A. Donhofer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recognition of guanosine by dissimilar tRNA methyltransferases
- (2012) R. Sakaguchi et al. RNA
- Relacin, a Novel Antibacterial Agent Targeting the Stringent Response
- (2012) Ezequiel Wexselblatt et al. PLoS Pathogens
- Molecular Basis for the Selectivity of Antituberculosis Compounds Capreomycin and Viomycin
- (2011) Rashid Akbergenov et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Synthesis and SAR of novel benzoxaboroles as a new class of β-lactamase inhibitors
- (2011) Yi Xia et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles
- (2011) Yong-Kang Zhang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Aminoacyl-tRNA synthetase inhibitors as potential antibiotics
- (2011) Gaston H.M. Vondenhoff et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Characterization of benzoxaborole-based antifungal resistance mutations demonstrates that editing depends on electrostatic stabilization of the leucyl-tRNA synthetase editing cap
- (2011) Jaya Sarkar et al. FEBS LETTERS
- Structural basis for a new tetracycline resistance mechanism relying on the TetX monooxygenase
- (2011) Gesa Volkers et al. FEBS LETTERS
- Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis
- (2011) Robert T Jacobs et al. Future Medicinal Chemistry
- Design, Synthesis, and Structure−Activity Relationship ofTrypanosoma bruceiLeucyl-tRNA Synthetase Inhibitors as Antitrypanosomal Agents
- (2011) Dazhong Ding et al. JOURNAL OF MEDICINAL CHEMISTRY
- Active Starvation Responses Mediate Antibiotic Tolerance in Biofilms and Nutrient-Limited Bacteria
- (2011) D. Nguyen et al. SCIENCE
- SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis
- (2011) Robert T. Jacobs et al. PLoS Neglected Tropical Diseases
- Transfer RNA-derived fragments: origins, processing, and functions
- (2011) Andrew Sobala et al. Wiley Interdisciplinary Reviews-RNA
- Synthesis and structure–activity relationships of novel benzoxaboroles as a new class of antimalarial agents
- (2010) Yong-Kang Zhang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Aminoglycoside modifying enzymes
- (2010) Maria S. Ramirez et al. DRUG RESISTANCE UPDATES
- Enzymatic Hydrolysis of Trehalose Dimycolate Releases Free Mycolic Acids during Mycobacterial Growth in Biofilms
- (2010) Anil K. Ojha et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Influence of the Substituents on the Structure and Properties of Benzoxaboroles
- (2010) Agnieszka Adamczyk-Woźniak et al. JOURNAL OF PHYSICAL CHEMISTRY A
- The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome
- (2010) Robin E Stanley et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Discovery of Novel Benzoxaborole-Based Potent Antitrypanosomal Agents
- (2010) Dazhong Ding et al. ACS Medicinal Chemistry Letters
- Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors
- (2009) Elena Cressina et al. BIOORGANIC & MEDICINAL CHEMISTRY
- The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA
- (2009) B. El Yacoubi et al. NUCLEIC ACIDS RESEARCH
- An O-Phosphotransferase Catalyzes Phosphorylation of Hygromycin A in the Antibiotic-Producing Organism Streptomyces hygroscopicus
- (2008) V. Dhote et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Complex Ligand-Induced Conformational Changes in tRNAAspRevealed by Single-Nucleotide Resolution SHAPE Chemistry†
- (2008) Bin Wang et al. BIOCHEMISTRY
- Bacterial RNase P RNA Is a Drug Target for Aminoglycoside−Arginine Conjugates
- (2008) Alexander Berchanski et al. BIOCONJUGATE CHEMISTRY
- Mistranslation of Membrane Proteins and Two-Component System Activation Trigger Antibiotic-Mediated Cell Death
- (2008) Michael A. Kohanski et al. CELL
- Inhibition ofHelicobacter pyloriAminoacyl-tRNA Amidotransferase by Puromycin Analogues
- (2008) Christian Balg et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Growth ofMycobacterium tuberculosisbiofilms containing free mycolic acids and harbouring drug-tolerant bacteria
- (2008) Anil K. Ojha et al. MOLECULAR MICROBIOLOGY
- Toward a more complete view of tRNA biology
- (2008) Richard Giegé NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Pentamidine binds to tRNA through non-specific hydrophobic interactions and inhibits aminoacylation and translation
- (2008) Tao Sun et al. NUCLEIC ACIDS RESEARCH
- The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
- (2008) D. N. Wilson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation