Eucalyptol Inhibits Amyloid-β-Induced Barrier Dysfunction in Glucose-Exposed Retinal Pigment Epithelial Cells and Diabetic Eyes

Effects of concentration of amyloid β (Aβ) on viability of cultured retinal pigment epithelial cells

(2019) Naonori Masuda et al.   BMC Ophthalmology

High-glucose induces retinal pigment epithelium mitochondrial pathways of apoptosis and inhibits mitophagy by regulating ROS/PINK1/Parkin signal pathway

(2019) Yuanping Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Protective effect of diphlorethohydroxycarmalol against oxidative stress-induced DNA damage and apoptosis in retinal pigment epithelial cells

(2019) Cheol Park et al.   Cutaneous and Ocular Toxicology

Hydrogen Sulfide Attenuates High Glucose-Induced Human Retinal Pigment Epithelial Cell Inflammation by Inhibiting ROS Formation and NLRP3 Inflammasome Activation

(2019) Peng Wang et al.   MEDIATORS OF INFLAMMATION

Metabolic Deregulation of the Blood-Outer Retinal Barrier in Retinitis Pigmentosa

(2019) Wei Wang et al.   Cell Reports

Insights into Eucalyptus genus chemical constituents, biological activities and health-promoting effects

(2019) Bahare Salehi et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Tight Junctions of the Outer Blood Retina Barrier

(2019) Aisling Naylor et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Eucalyptol Inhibits Advanced Glycation End Products-Induced Disruption of Podocyte Slit Junctions by Suppressing Rage-Erk-C-Myc Signaling Pathway

(2018) Dong Yeon Kim et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Targeted inhibition of RAGE reduces amyloid-β influx across the blood-brain barrier and improves cognitive deficits in db/db mice

(2018) Hao Wang et al.   NEUROPHARMACOLOGY

Autophagy Dysfunction and Oxidative Stress, Two Related Mechanisms Implicated in Retinitis Pigmentosa

(2018) Mari-Luz Moreno et al.   Frontiers in Physiology

NAP modulates hyperglycemic-inflammatory event of diabetic retina by counteracting outer blood retinal barrier damage

(2018) Agata Grazia D'Amico et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Protection of Kaempferol on Oxidative Stress-Induced Retinal Pigment Epithelial Cell Damage

(2018) Weiwei Du et al.   Oxidative Medicine and Cellular Longevity

Mechanism involved in insulin resistance via accumulation of β-amyloid and neurofibrillary tangles: link between type 2 diabetes and Alzheimer’s disease

(2018) Sima Kianpour Rad et al.   Drug Design Development and Therapy

Puerarin inhibits amyloid β-induced NLRP3 inflammasome activation in retinal pigment epithelial cells via suppressing ROS-dependent oxidative and endoplasmic reticulum stresses

(2017) Ke Wang et al.   EXPERIMENTAL CELL RESEARCH

The Link between Type 2 Diabetes and Neurodegeneration: Roles for Amyloid-β, Amylin, and Tau Proteins

(2017) Prashant Bharadwaj et al.   JOURNAL OF ALZHEIMERS DISEASE

Effects of diabetic retinopathy on the barrier functions of the retinal pigment epithelium

(2017) Tina Xia et al.   VISION RESEARCH

Eucalyptol ameliorates Snail1/β-catenin-dependent diabetic disjunction of renal tubular epithelial cells and tubulointerstitial fibrosis

(2017) Dong Yeon Kim et al.   Oncotarget

Risk of Incident Alzheimer's Disease in Diabetic Patients: A Systematic Review of Prospective Trials

(2017) Daniel Kopf et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice

(2017) Tuhina Prasad et al.   Scientific Reports

Retinitis pigmentosa-associated cystoid macular oedema: pathogenesis and avenues of intervention

(2016) S Strong et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Diabetes and Alzheimer’s disease crosstalk

(2016) David Baglietto-Vargas et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Recent Advances in Treatment of Retinitis Pigmentosa

(2015) Yuxi He et al.   Current Stem Cell Research & Therapy

Botanical Compounds: Effects on Major Eye Diseases

(2013) Tuan-Phat Huynh et al.   Evidence-based Complementary and Alternative Medicine

1,8-Cineole (Eucalyptol) Mitigates Inflammation in Amyloid Beta Toxicated PC12 Cells: Relevance to Alzheimer’s Disease

(2013) Andleeb Khan et al.   NEUROCHEMICAL RESEARCH

Molecular links between Alzheimer’s disease and diabetes mellitus

(2013) Y. Yang et al.   NEUROSCIENCE

High Glucose Promotes Aβ Production by Inhibiting APP Degradation

(2013) Yi Yang et al.   PLoS One

Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions

(2013) Ingeborg Klaassen et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Matrix Metalloproteinase-2-Mediated Occludin Degradation and Caveolin-1-Mediated Claudin-5 Redistribution Contribute to Blood-Brain Barrier Damage in Early Ischemic Stroke Stage

(2012) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Molecular mechanisms linking diabetes mellitus and Alzheimer disease: beta-amyloid peptide, insulin signaling, and neuronal function

(2011) Shuko Takeda et al.   Molecular BioSystems

Integration of tight junctions and claudins with the barrier functions of the retinal pigment epithelium

(2011) Lawrence J. Rizzolo et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Blood-Retinal Barrier

(2010) José Cunha-Vaz et al.   EUROPEAN JOURNAL OF OPHTHALMOLOGY

Agents that block advanced glycation end product (AGE)-RAGE (receptor for AGEs)-oxidative stress system: a novel therapeutic strategy for diabetic vascular complications

(2008) Sho-ichi Yamagishi et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS