Skewed CD39/CD73/adenosine pathway contributes to B-cell hyperactivation and disease progression in patients with chronic hepatitis B

Phenotypic and functional differences of HBV core-specific versus HBV polymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load

(2019) Anita Schuch et al.   GUT

Immunological cure of HBV infection

(2019) Julia Lang et al.   Hepatology International

PD-1 blockade partially recovers dysfunctional virus–specific B cells in chronic hepatitis B infection

(2018) Loghman Salimzadeh et al.   JOURNAL OF CLINICAL INVESTIGATION

Circulating and intrahepatic antiviral B cells are defective in hepatitis B

(2018) Alice R. Burton et al.   JOURNAL OF CLINICAL INVESTIGATION

Fine needle aspirates comprehensively sample intrahepatic immunity

(2018) Upkar S Gill et al.   GUT

IL-2hightissue-resident T cells in the human liver: Sentinels for hepatotropic infection

(2017) Laura J. Pallett et al.   JOURNAL OF EXPERIMENTAL MEDICINE

EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection

(2017) Pietro Lampertico et al.   JOURNAL OF HEPATOLOGY

Down-regulation of CD73 on B cells of patients with viremic HIV correlates with B cell activation and disease progression

(2017) Eun-Seong Kim et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Protective role of hypoxia-inducible factor-1α-dependent CD39 and CD73 in fulminant acute liver failure

(2017) Eunyoung Tak et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Adaptive immunity in HBV infection

(2016) Antonio Bertoletti et al.   JOURNAL OF HEPATOLOGY

Reversal of B-cell hyperactivation and functional impairment is associated with HBsAg seroconversion in chronic hepatitis B patients

(2015) Xiangsheng Xu et al.   Cellular & Molecular Immunology

CD73 and CD39 ectonucleotidases in T cell differentiation: Beyond immunosuppression

(2015) María Rosa Bono et al.   FEBS LETTERS

AASLD guidelines for treatment of chronic hepatitis B

(2015) Norah A. Terrault et al.   HEPATOLOGY

Hepatitis B Virus (HBV) Core-Related Antigen During Nucleos(t)ide Analog Therapy Is Related to Intra-hepatic HBV Replication and Development of Hepatocellular Carcinoma

(2015) Masao Honda et al.   JOURNAL OF INFECTIOUS DISEASES

The global burden of liver disease: The major impact of China

(2014) Fu-Sheng Wang et al.   HEPATOLOGY

Nutrient Sensing via mTOR in T Cells Maintains a Tolerogenic Microenvironment

(2014) Duncan Howie et al.   Frontiers in Immunology

Adenosine production by human B cells and B cell-mediated suppression of activated T cells

(2013) Z. Saze et al.   BLOOD

Decreased Vδ2 γδ T Cells Associated With Liver Damage by Regulation of Th17 Response in Patients With Chronic Hepatitis B

(2013) Xiaoli Wu et al.   JOURNAL OF INFECTIOUS DISEASES

Adenosine signaling during acute and chronic disease states

(2013) Harry Karmouty-Quintana et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Metformin inhibits hepatitis B virus protein production and replication in human hepatoma cells

(2013) Y.-H. Xun et al.   JOURNAL OF VIRAL HEPATITIS

Dependence of Immunoglobulin Class Switch Recombination in B Cells on Vesicular Release of ATP and CD73 Ectonucleotidase Activity

(2013) Francesca Schena et al.   Cell Reports

Liver grafts from CD39-overexpressing rodents are protected from ischemia reperfusion injury due to reduced numbers of resident CD4+T cells

(2012) Sandra Pommey et al.   HEPATOLOGY

Liver damage and systemic inflammatory responses are exacerbated by the genetic deletion of CD39 in total hepatic ischemia

(2011) Xiaofeng Sun et al.   Purinergic Signalling

Enhanced B-cell differentiation and reduced proliferative capacity in chronic hepatitis C and chronic hepatitis B virus infections

(2010) Barbara Oliviero et al.   JOURNAL OF HEPATOLOGY

SP1-Dependent Induction of CD39 Facilitates Hepatic Ischemic Preconditioning

(2010) M. L. Hart et al.   JOURNAL OF IMMUNOLOGY

Adenosine signaling contributes to ethanol-induced fatty liver in mice

(2009) Zhongsheng Peng et al.   JOURNAL OF CLINICAL INVESTIGATION

Host immunity influences disease progression and antiviral efficacy in humans infected with hepatitis B virus

(2009) Fu-Sheng Wang et al.   Expert Review of Gastroenterology & Hepatology

Ecto-5′-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis

(2008) Zhongsheng Peng et al.   FASEB JOURNAL

Extracellular Adenosine Production by Ecto-5′-Nucleotidase Protects During Murine Hepatic Ischemic Preconditioning

(2008) Melanie L. Hart et al.   GASTROENTEROLOGY