Engineering disease resistant plants through CRISPR-Cas9 technology

Integrated Transcriptomic and Un-Targeted Metabolomics Analysis Reveals Mulberry Fruit (Morus atropurpurea) in Response to Sclerotiniose Pathogen Ciboria shiraiana Infection

(2020) Lijun Bao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metabolomics as an Emerging Tool for the Study of Plant–Pathogen Interactions

(2020) Fernanda R. Castro-Moretti et al.   Metabolites

Precision genome editing in plants: state-of-the-art in CRISPR/Cas9-based genome engineering

(2020) Naoki Wada et al.   BMC PLANT BIOLOGY

Broadening the GMO risk assessment in the EU for genome editing technologies in agriculture

(2020) Katharina Kawall et al.   Environmental Sciences Europe

Creating highly efficient resistance against Wheat dwarf virus in barley by employing CRISPR/Cas9 system

(2019) András Kis et al.   PLANT BIOTECHNOLOGY JOURNAL

CRISPR/Cas9: A Novel Weapon in the Arsenal to Combat Plant Diseases

(2019) Ayan Das et al.   Frontiers in Plant Science

Methodologies for Improving HDR Efficiency

(2019) Mingjie Liu et al.   Frontiers in Genetics

Genetic Engineering for Disease Resistance in Plants: Recent Progress and Future Perspectives

(2019) Oliver Xiaoou Dong et al.   PLANT PHYSIOLOGY

Mimicking natural polymorphism in eIF4E by CRISPR-Cas9 base editing is associated with resistance to potyviruses

(2019) Anna Bastet et al.   PLANT BIOTECHNOLOGY JOURNAL

Genome editing for plant disease resistance: applications and perspectives

(2019) Kangquan Yin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Applications of the CRISPR/Cas9 System for Rice Grain Quality Improvement: Perspectives and Opportunities

(2019) Sajid Fiaz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antibiotics bioremediation: Perspectives on its ecotoxicity and resistance

(2019) Mohit Kumar et al.   ENVIRONMENT INTERNATIONAL

CRISPR/Cas Genome Editing and Precision Plant Breeding in Agriculture

(2019) Kunling Chen et al.   Annual Review of Plant Biology

The next generation of CRISPR–Cas technologies and applications

(2019) Adrian Pickar-Oliver et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biosynthesis and secretion of the microbial sulfated peptide RaxX and binding to the rice XA21 immune receptor

(2019) Dee Dee Luu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Harnessing Genome Editing Techniques to Engineer Disease Resistance in Plants

(2019) Muntazir Mushtaq et al.   Frontiers in Plant Science

Microbiota-mediated disease resistance in plants

(2019) Nathan Vannier et al.   PLoS Pathogens

CRISPR technology is revolutionizing the improvement of tomato and other fruit crops

(2019) Tian Wang et al.   Horticulture Research

Exploration of Plant-Microbe Interactions for Sustainable Agriculture in CRISPR Era

(2019) Rahul Mahadev Shelake et al.   Microorganisms

Engineering Abiotic Stress Tolerance via CRISPR-Cas mediated genome editing

(2019) Syed Adeel Zafar et al.   JOURNAL OF EXPERIMENTAL BOTANY

CRISPR Crops: Plant Genome Editing Toward Disease Resistance

(2018) Thorsten Langner et al.   Annual Review of Phytopathology

Using Metagenomics to Characterize an Expanding Virosphere

(2018) Yong-Zhen Zhang et al.   CELL

VOCs-mediated hormonal signaling and crosstalk with plant growth promoting microbes

(2018) Swati Tyagi et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Efficient genome editing in Fusarium oxysporum based on CRISPR/Cas9 ribonucleoprotein complexes

(2018) Qiang Wang et al.   FUNGAL GENETICS AND BIOLOGY

With a free pass, CRISPR-edited plants reach market in record time

(2018) Emily Waltz   NATURE BIOTECHNOLOGY

A plant pathogen modulates the effects of secondary metabolites on the performance and immune function of an insect herbivore

(2018) Elena Rosa et al.   OIKOS

Trans-species synthetic gene design allows resistance pyramiding and broad-spectrum engineering of virus resistance in plants

(2018) Anna Bastet et al.   PLANT BIOTECHNOLOGY JOURNAL

Establishing RNA virus resistance in plants by harnessing CRISPR immune system

(2018) Tong Zhang et al.   PLANT BIOTECHNOLOGY JOURNAL

Novel alleles of rice eIF4G generated by CRISPR/Cas9-targeted mutagenesis confer resistance to Rice tungro spherical virus

(2018) Anca Macovei et al.   PLANT BIOTECHNOLOGY JOURNAL

Simultaneous CRISPR/Cas9-mediated editing of cassava eIF4E isoforms nCBP-1 and nCBP-2 reduces cassava brown streak disease symptom severity and incidence

(2018) Michael A Gomez et al.   PLANT BIOTECHNOLOGY JOURNAL

Review: Potential biotechnological assets related to plant immunity modulation applicable in engineering disease-resistant crops

(2018) Marilia Santos Silva et al.   PLANT SCIENCE

A Novel Tomato Fusarium Wilt Tolerance Gene

(2018) Cahya Prihatna et al.   Frontiers in Microbiology

Targeted Deletion of the USTA and UvSLT2 Genes Efficiently in Ustilaginoidea virens With the CRISPR-Cas9 System

(2018) Yafeng Liang et al.   Frontiers in Plant Science

Transient Expression of CRISPR/Cas9 Machinery Targeting TcNPR3 Enhances Defense Response in Theobroma cacao

(2018) Andrew S. Fister et al.   Frontiers in Plant Science

Disease Resistance Mechanisms in Plants

(2018) Ethan Andersen et al.   Genes

Knockout of SlMAPK3 Reduced Disease Resistance to Botrytis cinerea in Tomato Plants

(2018) Shujuan Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window

(2018) Shakked O. Halperin et al.   NATURE

EvolvR-ing to targeted mutagenesis

(2018) Saheli Sadanand   NATURE BIOTECHNOLOGY

Design of a bacterial speck resistant tomato by CRISPR/Cas9-mediated editing of SlJAZ2

(2018) Andrés Ortigosa et al.   PLANT BIOTECHNOLOGY JOURNAL

CRISPR-Cas9 ribonucleoprotein-mediated co-editing and counterselection in the rice blast fungus

(2018) Andrew J. Foster et al.   Scientific Reports

The Enhancement of Plant Disease Resistance Using CRISPR/Cas9 Technology

(2018) Virginia M. G. Borrelli et al.   Frontiers in Plant Science

CRISPR/Cas precision: do we need to worry about off-targeting in plants?

(2018) Florian Hahn et al.   PLANT CELL REPORTS

Metabolomics Analysis of Soybean Hypocotyls in Response to Phytophthora sojae Infection

(2018) Longming Zhu et al.   Frontiers in Plant Science

Rapid and user-friendly open-source CRISPR/Cas9 system for single- or multi-site editing of tomato genome

(2018) Nan Hu et al.   Horticulture Research

A technological and regulatory outlook on CRISPR crop editing

(2017) Rea Globus et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Disruption of OsSEC3A increases the content of salicylic acid and induces plant defense responses in rice

(2017) Jin Ma et al.   JOURNAL OF EXPERIMENTAL BOTANY

Signaling Mechanisms Underlying Resistance Responses: What Have We Learned, and How Is It Being Applied?

(2017) Aardra Kachroo et al.   PHYTOPATHOLOGY

CRISPR/Cas9-mediated efficient targeted mutagenesis in grape in the first generation

(2017) Xianhang Wang et al.   PLANT BIOTECHNOLOGY JOURNAL

Engineering canker-resistant plants through CRISPR/Cas9-targeted editing of the susceptibility gene CsLOB1 promoter in citrus

(2017) Aihong Peng et al.   PLANT BIOTECHNOLOGY JOURNAL

Simultaneous modification of three homoeologs of TaEDR1 by genome editing enhances powdery mildew resistance in wheat

(2017) Yunwei Zhang et al.   PLANT JOURNAL

In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni

(2017) Eunji Kim et al.   Nature Communications

Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes

(2017) Zhen Liang et al.   Nature Communications

Genome Editing in Cotton with the CRISPR/Cas9 System

(2017) Wei Gao et al.   Frontiers in Plant Science

A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans

(2017) Rebecca S. Shapiro et al.   Nature Microbiology

Rapid generation of a transgene-free powdery mildew resistant tomato by genome deletion

(2017) Vladimir Nekrasov et al.   Scientific Reports

Multiple Disease Resistance in Plants

(2016) Tyr Wiesner-Hanks et al.   Annual Review of Phytopathology

Structure and Engineering of Francisella novicida Cas9

(2016) Hisato Hirano et al.   CELL

Advances and perspectives on the use of CRISPR/Cas9 systems in plant genomics research

(2016) Degao Liu et al.   CURRENT OPINION IN PLANT BIOLOGY

Genome editing in Ustilago maydis using the CRISPR–Cas system

(2016) Mariana Schuster et al.   FUNGAL GENETICS AND BIOLOGY

Engineering of CRISPR/Cas9-mediated potyvirus resistance in transgene-freeArabidopsisplants

(2016) Douglas E. Pyott et al.   MOLECULAR PLANT PATHOLOGY

Development of broad virus resistance in non-transgenic cucumber using CRISPR/Cas9 technology

(2016) Jeyabharathy Chandrasekaran et al.   MOLECULAR PLANT PATHOLOGY

Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome

(2016) Maximilian Müller et al.   MOLECULAR THERAPY

JAZ2 controls stomata dynamics during bacterial invasion

(2016) Selena Gimenez-Ibanez et al.   NEW PHYTOLOGIST

Plant Microbe Interactions in Post Genomic Era: Perspectives and Applications

(2016) Jahangir Imam et al.   Frontiers in Microbiology

CRISPR/Cas9: A Tool to Circumscribe Cotton Leaf Curl Disease

(2016) Zafar Iqbal et al.   Frontiers in Plant Science

DNA-Free Genetically Edited Grapevine and Apple Protoplast Using CRISPR/Cas9 Ribonucleoproteins

(2016) Mickael Malnoy et al.   Frontiers in Plant Science

Enhanced Rice Blast Resistance by CRISPR/Cas9-Targeted Mutagenesis of the ERF Transcription Factor Gene OsERF922

(2016) Fujun Wang et al.   PLoS One

Genome-Wide Assessment of Efficiency and Specificity in CRISPR/Cas9 Mediated Multiple Site Targeting in Arabidopsis

(2016) Brenda A. Peterson et al.   PLoS One

CRISPR/Cas9-Mediated Immunity to Geminiviruses: Differential Interference and Evasion

(2016) Zahir Ali et al.   Scientific Reports

Efficient disruption and replacement of an effector gene in the oomycetePhytophthora sojaeusing CRISPR/Cas9

(2015) Yufeng Fang et al.   MOLECULAR PLANT PATHOLOGY

In vivo genome editing using Staphylococcus aureus Cas9

(2015) F. Ann Ran et al.   NATURE

An updated evolutionary classification of CRISPR–Cas systems

(2015) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Beyond editing: repurposing CRISPR–Cas9 for precision genome regulation and interrogation

(2015) Antonia A. Dominguez et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Modification of the PthA4 effector binding elements in Type I CsLOB1 promoter using Cas9/sgRNA to produce transgenic Duncan grapefruit alleviating XccΔpthA4:dCsLOB1.3 infection

(2015) Hongge Jia et al.   PLANT BIOTECHNOLOGY JOURNAL

Gene targeting by the TAL effector PthXo2 reveals cryptic resistance gene for bacterial blight of rice

(2015) Junhui Zhou et al.   PLANT JOURNAL

Phylogenomics of Xanthomonas field strains infecting pepper and tomato reveals diversity in effector repertoires and identifies determinants of host specificity

(2015) Allison R. Schwartz et al.   Frontiers in Microbiology

Establishing a CRISPR–Cas-like immune system conferring DNA virus resistance in plants

(2015) Xiang Ji et al.   Nature Plants

Conferring resistance to geminiviruses with the CRISPR–Cas prokaryotic immune system

(2015) Nicholas J. Baltes et al.   Nature Plants

Efficient CRISPR/Cas9-mediated Targeted Mutagenesis in Populus in the First Generation

(2015) Di Fan et al.   Scientific Reports

Plant Cell Wall–Degrading Enzymes and Their Secretion in Plant-Pathogenic Fungi

(2014) Christian P. Kubicek et al.   Annual Review of Phytopathology

Systems biology as an approach for deciphering microbial interactions

(2014) P. Kumar Singh et al.   Briefings in Functional Genomics

A trade off between mlo resistance to powdery mildew and increased susceptibility of barley to a newly important disease, Ramularia leaf spot

(2014) Graham R. D. McGrann et al.   JOURNAL OF EXPERIMENTAL BOTANY

The zigzag model of plant-microbe interactions: is it time to move on?

(2014) Leighton Pritchard et al.   MOLECULAR PLANT PATHOLOGY

Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew

(2014) Yanpeng Wang et al.   NATURE BIOTECHNOLOGY

Genome editing in rice and wheat using the CRISPR/Cas system

(2014) Qiwei Shan et al.   Nature Protocols

Large chromosomal deletions and heritable small genetic changes induced by CRISPR/Cas9 in rice

(2014) Huanbin Zhou et al.   NUCLEIC ACIDS RESEARCH

DOWNY MILDEW RESISTANT 6 and DMR6-LIKE OXYGENASE 1 are partially redundant but distinct suppressors of immunity in Arabidopsis

(2014) Tieme Zeilmaker et al.   PLANT JOURNAL

Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering inArabidopsis thaliana

(2014) Friedrich Fauser et al.   PLANT JOURNAL

Efficient Gene Editing in Tomato in the First Generation Using the Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-Associated9 System

(2014) C. Brooks et al.   PLANT PHYSIOLOGY

RNA-Guided Genome Editing in Plants Using a CRISPR–Cas System

(2013) Kabin Xie et al.   Molecular Plant

Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease

(2013) Vladimir Nekrasov et al.   NATURE BIOTECHNOLOGY

Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice

(2013) Wenzhi Jiang et al.   NUCLEIC ACIDS RESEARCH

Powdery Mildew Resistance in Tomato by Impairment of SlPMR4 and SlDMR1

(2013) Robin P. Huibers et al.   PLoS One

Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

(2013) Z. Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo genome editing using a high-efficiency TALEN system

(2012) Victoria M. Bedell et al.   NATURE

Tricking the Guard: Exploiting Plant Defense for Disease Susceptibility

(2012) J. Lorang et al.   SCIENCE

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

CRISPR-Cas Systems in Bacteria and Archaea: Versatile Small RNAs for Adaptive Defense and Regulation

(2011) Devaki Bhaya et al.   Annual Review of Genetics

Plant stomata: a checkpoint of host immunity and pathogen virulence

(2010) Weiqing Zeng et al.   CURRENT OPINION IN BIOTECHNOLOGY

Loss of susceptibility as a novel breeding strategy for durable and broad-spectrum resistance

(2009) Stefano Pavan et al.   MOLECULAR BREEDING

From bacterial avirulence genes to effector functions via thehrpdelivery system: an overview of 25 years of progress in our understanding of plant innate immunity

(2009) JOHN W. MANSFIELD   MOLECULAR PLANT PATHOLOGY

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

(2009) Vipula K. Shukla et al.   NATURE

Naturally Occurring Broad-Spectrum Powdery Mildew Resistance in a Central American Tomato Accession Is Caused by Loss of Mlo Function

(2007) Yuling Bai et al.   MOLECULAR PLANT-MICROBE INTERACTIONS