Nuclear Envelope Proteins Modulating the Heterochromatin Formation and Functions in Fission Yeast

ESCRT-III/Vps4 Controls Heterochromatin-Nuclear Envelope Attachments

(2020) Gerard H. Pieper et al.   DEVELOPMENTAL CELL

LEM2 phase separation promotes ESCRT-mediated nuclear envelope reformation

(2020) Alexander von Appen et al.   NATURE

Lem2 and Lnp1 maintain the membrane boundary between the nuclear envelope and endoplasmic reticulum

(2020) Yasuhiro Hirano et al.   Communications Biology

The very-long-chain fatty acid elongase Elo2 rescues lethal defects associated with loss of the nuclear barrier function in fission yeast cells

(2019) Yasuha Kinugasa et al.   JOURNAL OF CELL SCIENCE

Nuclear membrane protein Lem2 regulates nuclear size through membrane flow

(2019) Kazunori Kume et al.   Nature Communications

ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage

(2019) Jessica Willan et al.   Oncogenesis

CPF Recruitment to Non-canonical Transcription Termination Sites Triggers Heterochromatin Assembly and Gene Silencing

(2019) Tommy V. Vo et al.   Cell Reports

Asymmetrical localization of Nup107-160 subcomplex components within the nuclear pore complex in fission yeast

(2019) Haruhiko Asakawa et al.   PLoS Genetics

H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly

(2019) Eriko Oya et al.   EMBO REPORTS

Core Components of the Nuclear Pore Bind Distinct States of Chromatin and Contribute to Polycomb Repression

(2019) Alejandro Gozalo et al.   MOLECULAR CELL

Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance

(2019) Nahid Iglesias et al.   MOLECULAR CELL

HP1 reshapes nucleosome core to promote phase separation of heterochromatin

(2019) S. Sanulli et al.   NATURE

Nuclear Mechanics in the Fission Yeast

(2019) Paola Gallardo et al.   Cells

Positioning Heterochromatin at the Nuclear Periphery Suppresses Histone Turnover to Promote Epigenetic Inheritance

(2019) Sahana Holla et al.   CELL

The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions

(2019) Magdalena Murawska et al.   MOLECULAR CELL

Polymerase pausing induced by sequence-specific RNA-binding protein drives heterochromatin assembly

(2018) Jahan-Yar Parsa et al.   GENES & DEVELOPMENT

Lem2 is retained at the nuclear envelope through its interaction with Bqt4 in fission yeast

(2018) Yasuhiro Hirano et al.   GENES TO CELLS

In situ architecture of the algal nuclear pore complex

(2018) Shyamal Mosalaganti et al.   Nature Communications

Distinct ‘safe zones’ at the nuclear envelope ensure robust replication of heterochromatic chromosome regions

(2018) Hani Ebrahimi et al.   eLife

Integrative structure and functional anatomy of a nuclear pore complex

(2018) Seung Joong Kim et al.   NATURE

Anti-silencing factor Epe1 associates with SAGA to regulate transcription within heterochromatin

(2018) Kehan Bao et al.   GENES & DEVELOPMENT

Structural insights into chromosome attachment to the nuclear envelope by an inner nuclear membrane protein Bqt4 in fission yeast

(2018) Chunyi Hu et al.   NUCLEIC ACIDS RESEARCH

The Inner Nuclear Membrane Protein Bqt4 in Fission Yeast Contains a DNA-Binding Domain Essential for Telomere Association with the Nuclear Envelope

(2018) Chunyi Hu et al.   STRUCTURE

Function of nuclear membrane proteins in shaping the nuclear envelope integrity during closed mitosis

(2017) Hui-Ju Yang et al.   JOURNAL OF BIOCHEMISTRY

Compositionally distinct nuclear pore complexes of functionally distinct dimorphic nuclei in the ciliateTetrahymena

(2017) Masaaki Iwamoto et al.   JOURNAL OF CELL SCIENCE

Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy

(2017) H. Diego Folco et al.   NATURE

LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells

(2017) Mingyu Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nuclear Pore Complex as a Flexible and Dynamic Gate

(2016) Kevin E. Knockenhauer et al.   CELL

Inner nuclear membrane protein Lem2 facilitates Rad3-mediated checkpoint signaling under replication stress induced by nucleotide depletion in fission yeast

(2016) Yong-jie Xu   CELLULAR SIGNALLING

Uniquely designed nuclear structures of lower eukaryotes

(2016) Masaaki Iwamoto et al.   CURRENT OPINION IN CELL BIOLOGY

Control of heterochromatin localization and silencing by the nuclear membrane protein Lem2

(2016) Ramón Ramos Barrales et al.   GENES & DEVELOPMENT

Inner nuclear membrane protein Lem2 augments heterochromatin formation in response to nutritional conditions

(2016) Yoshie Tange et al.   GENES TO CELLS

Role of Inner Nuclear Membrane Protein Complex Lem2-Nur1 in Heterochromatic Gene Silencing

(2016) Shahid Banday et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lunapark Is a Component of a Ubiquitin Ligase Complex Localized to the Endoplasmic Reticulum Three-way Junctions

(2016) Yupeng Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis and degradation pathways, functions, and pathology of ceramides and epidermal acylceramides

(2016) Akio Kihara   PROGRESS IN LIPID RESEARCH

RNA interference is essential for cellular quiescence

(2016) B. Roche et al.   SCIENCE

Architecture of the symmetric core of the nuclear pore

(2016) D. H. Lin et al.   SCIENCE

Molecular architecture of the inner ring scaffold of the human nuclear pore complex

(2016) J. Kosinski et al.   SCIENCE

Spatial organization of theSchizosaccharomyces pombegenome within the nucleus

(2016) Atsushi Matsuda et al.   YEAST

Shugoshin forms a specialized chromatin domain at subtelomeres that regulates transcription and replication timing

(2016) Sanki Tashiro et al.   Nature Communications

Interactome Mapping Reveals the Evolutionary History of the Nuclear Pore Complex

(2016) Samson O. Obado et al.   PLOS BIOLOGY

A Novel Epigenetic Silencing Pathway Involving the Highly Conserved 5’-3’ Exoribonuclease Dhp1/Rat1/Xrn2 in Schizosaccharomyces pombe

(2016) James Franklin Tucker et al.   PLoS Genetics

Cooperation of the ER-shaping proteins atlastin, lunapark, and reticulons to generate a tubular membrane network

(2016) Songyu Wang et al.   eLife

Src1 is a Protein of the Inner Nuclear Membrane Interacting with the Dictyostelium Lamin NE81

(2016) Petros Batsios et al.   Cells

Making the LINC: SUN and KASH protein interactions

(2015) Dae In Kim et al.   BIOLOGICAL CHEMISTRY

ESCRT-III controls nuclear envelope reformation

(2015) Yolanda Olmos et al.   NATURE

Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing

(2015) Marina Vietri et al.   NATURE

In situ structural analysis of the human nuclear pore complex

(2015) Alexander von Appen et al.   NATURE

Conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing

(2015) Venkata R. Chalamcharla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Restricted epigenetic inheritance of H3K9 methylation

(2015) P. N. C. B. Audergon et al.   SCIENCE

Epigenetic Regulation of Chromatin States inSchizosaccharomyces pombe

(2015) Robin C. Allshire et al.   Cold Spring Harbor Perspectives in Biology

RNAi and Heterochromatin Assembly

(2015) Robert Martienssen et al.   Cold Spring Harbor Perspectives in Biology

Highly condensed chromatins are formed adjacent to subtelomeric and decondensed silent chromatin in fission yeast

(2015) Atsushi Matsuda et al.   Nature Communications

Intrinsic Toxicity of Unchecked Heterochromatin Spread Is Suppressed by Redundant Chromatin Boundary Functions in Schizosacchromyces pombe

(2015) Jennifer F. Garcia et al.   G3-Genes Genomes Genetics

The Fun30 Chromatin Remodeler Fft3 Controls Nuclear Organization and Chromatin Structure of Insulators and Subtelomeres in Fission Yeast

(2015) Babett Steglich et al.   PLoS Genetics

A method of correlative light and electron microscopy for yeast cells

(2014) Haruhiko Asakawa et al.   MICRON

Lunapark stabilizes nascent three-way junctions in the endoplasmic reticulum

(2014) Shuliang Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic inheritance uncoupled from sequence-specific recruitment

(2014) K. Ragunathan et al.   SCIENCE

Integrated Structural Analysis of the Human Nuclear Pore Complex Scaffold

(2013) Khanh Huy Bui et al.   CELL

LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

(2013) Irina Solovei et al.   CELL

A conserved ncRNA-binding protein recruits silencing factors to heterochromatin through an RNAi-independent mechanism

(2013) D. B. Marina et al.   GENES & DEVELOPMENT

Interaction of Nup53 with Ndc1 and Nup155 is required for nuclear pore complex assembly

(2013) Nathalie Eisenhardt et al.   JOURNAL OF CELL SCIENCE

Csi1 illuminates the mechanism and function of Rabl configuration

(2013) Haitong Hou et al.   Nucleus

Retrotransposons

(2012) David J. Finnegan   CURRENT BIOLOGY

Connecting the nucleus to the cytoskeleton by SUN–KASH bridges across the nuclear envelope

(2012) Erin C Tapley et al.   CURRENT OPINION IN CELL BIOLOGY

RNAi keeps Atf1-bound stress response genes in check at nuclear pores

(2012) K. J. Woolcock et al.   GENES & DEVELOPMENT

Lamin B Receptor Recognizes Specific Modifications of Histone H4 in Heterochromatin Formation

(2012) Yasuhiro Hirano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Csi1 links centromeres to the nuclear envelope for centromere clustering

(2012) Haitong Hou et al.   JOURNAL OF CELL BIOLOGY

ER network formation requires a balance of the dynamin-like GTPase Sey1p and the Lunapark family member Lnp1p

(2012) Shuliang Chen et al.   NATURE CELL BIOLOGY

Raf1 Is a DCAF for the Rik1 DDB1-Like Protein and Has Separable Roles in siRNA Generation and Chromatin Modification

(2012) Alessia Buscaino et al.   PLoS Genetics

Fission yeast Lem2 and Man1 perform fundamental functions of the animal cell nuclear lamina

(2012) Yanira Gonzalez et al.   Nucleus

The nuclear envelope proteome differs notably between tissues

(2012) Nadia Korfali et al.   Nucleus

Evolvement of LEM proteins as chromatin tethers at the nuclear periphery

(2011) Andreas Brachner et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The Cul4-Ddb1Cdt2 Ubiquitin Ligase Inhibits Invasion of a Boundary-Associated Antisilencing Factor into Heterochromatin

(2011) Sigurd Braun et al.   CELL

Insight into Structure and Assembly of the Nuclear Pore Complex by Utilizing the Genome of a Eukaryotic Thermophile

(2011) Stefan Amlacher et al.   CELL

KASH and SUN proteins

(2011) Daniel A. Starr   CURRENT BIOLOGY

RNA and epigenetic silencing: Insight from fission yeast

(2011) Derek B. Goto et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Inner nuclear membrane protein Ima1 is dispensable for intranuclear positioning of centromeres

(2011) Yasushi Hiraoka et al.   GENES TO CELLS

Defects in RNA quality control factors reveal RNAi-independent nucleation of heterochromatin

(2011) Francisca E Reyes-Turcu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Primal RNAs: The End of the Beginning?

(2010) Darryl Conte et al.   CELL

Stc1: A Critical Link between RNAi and Chromatin Modification Required for Heterochromatin Integrity

(2010) Elizabeth H. Bayne et al.   CELL

RNAi-dependent formation of heterochromatin and its diverse functions

(2010) Shiv IS Grewal   CURRENT OPINION IN GENETICS & DEVELOPMENT

Nuclear Retention of Fission Yeast Dicer Is a Prerequisite for RNAi-Mediated Heterochromatin Assembly

(2010) Stephan Emmerth et al.   DEVELOPMENTAL CELL

CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR

(2010) Mikel Zaratiegui et al.   NATURE

Identification and Characterization of Nuclear Pore Complex Components inArabidopsis thaliana

(2010) Kentaro Tamura et al.   PLANT CELL

Ceramide biosynthesis in keratinocyte and its role in skin function

(2009) Yukiko Mizutani et al.   BIOCHIMIE

Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

(2009) Irina Solovei et al.   CELL

The SUN Rises on Meiotic Chromosome Dynamics

(2009) Yasushi Hiraoka et al.   DEVELOPMENTAL CELL

Phosphorylation of Swi6/HP1 regulates transcriptional gene silencing at heterochromatin

(2009) A. Shimada et al.   GENES & DEVELOPMENT

Adult Ceramide Synthase 2 (CERS2)-deficient Mice Exhibit Myelin Sheath Defects, Cerebellar Degeneration, and Hepatocarcinomas

(2009) Silke Imgrund et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane proteins Bqt3 and -4 anchor telomeres to the nuclear envelope to ensure chromosomal bouquet formation

(2009) Yuji Chikashige et al.   JOURNAL OF CELL BIOLOGY

Role of the Ndc1 interaction network in yeast nuclear pore complex assembly and maintenance

(2009) Evgeny Onischenko et al.   JOURNAL OF CELL BIOLOGY

Evidence for a Shared Nuclear Pore Complex Architecture That Is Conserved from the Last Common Eukaryotic Ancestor

(2009) Jeffrey A. DeGrasse et al.   MOLECULAR & CELLULAR PROTEOMICS

CRL4s: the CUL4-RING E3 ubiquitin ligases

(2009) Sarah Jackson et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Schizosaccharomyces pombe JmjC-Protein, Msc1, Prevents H2A.Z Localization in Centromeric and Subtelomeric Chromatin Domains

(2009) Luke Buchanan et al.   PLoS Genetics

Nuclear architecture and gene regulation

(2008) Elena Fedorova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The fission yeast homologue of CENP-B, Abp1, regulates directionality of mating-type switching

(2008) Lorena Aguilar-Arnal et al.   EMBO JOURNAL

siRNA-Mediated Heterochromatin Establishment Requires HP1 and Is Associated with Antisense Transcription

(2008) Tetsushi Iida et al.   MOLECULAR CELL

HP1 Proteins Form Distinct Complexes and Mediate Heterochromatic Gene Silencing by Nonoverlapping Mechanisms

(2008) Mohammad R. Motamedi et al.   MOLECULAR CELL

TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway

(2008) Marc Bühler et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Roles of the Clr4 methyltransferase complex in nucleation, spreading and maintenance of heterochromatin

(2008) Ke Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Heterochromatin Integrity Affects Chromosome Reorganization After Centromere Dysfunction

(2008) K. Ishii et al.   SCIENCE